duoc ung dung lam thuoc co h6i va earn mau til cung sau khi sinh. Khac vdi oxytoxin, alcaloid cua loa mach gay co til cung khong phu thuoc VaG
trang thai cua til cung va co bop khong co tinh chat sinh ly nen khong
dung lam thuoc kich thich de.
- 'I'ren cac co tron khac: thuoc gay co nhe co tron khi phe' quan va co tron
tieu hoa, Vivay, khi dung lieu cao co th~ gay buon non, non va tieu chay.
Co che' tac dung: thuoc vua uc che vira kich thich receptor a- adrenergic (chat doi khang va chu van tung phan tren receptor a- adrenergic), khang serotoninergic va kich thich dopaminergic.
Chi dinh.
Dau nua dftu (migrain) va dau dftu do cac roi loan van mach khac. Co h6i til cung sau de.
Phong va dieu tri chay mau til cung sau khi sinh hoac sau khi nao thai.
Ttic dung hhong mong muon
Thuong g?P la roi lo~n tieu hoa (nhu bu6n non, non, tieu chay), roi lo~n cam giac va v~n dQng (nhu ao giac, gi~t cd, te dftu chi). Lieu cao, gay co m~ch m~nh, keo dai lam thieu mau cvc bQ,tl'ic m~ch ngo~i vi, ho~i til.
Chong chi dinh
Suy tuftn hoan ngo~i bien. Tang huyet ap.
Thieu mau cvc bQcd tim. Loet d~ day - ta trang. B~nh gan, th~n n~ng. PhV nu co thai, cho con bu.
Che'phiim va lieu dung
Ergotamin: thudng dieu tri dau nila dftu.
Dong 1- 2 mg/ Iftn, 1- 31ftnl 24h, tang lieu khong qua 6mg. Vien 1mg, 2mg.
Dihydroergotamin: dieu tri dau nila dftu va h~ huyet ap the dung
Tiem 1mg/ Iftn, tang lieu toi da 6mg/tuftn. Dong 3mg/ Iftn, 3lftnl 24h. Nen uang ngay truoc bua an.
Ergometrin (Ergonovin): thudng dung co h6i til cung: O,2mg/Iftn.
Tuong tcic thuoc
- Khong dung d6ng thdi cac alcaloid clja loa m~ch voi cac thuoc gay co m~ch va thuoc cudng giao cam vi gay co m~ch, tang huyet ap m~nh.
- Voi cac khang sinh macrolid (erythromycin) va cac thuOc uc che' enzym chuyenhoadgan lam tang d9<;tinh cua ergotaminva cac alcaloidcua loa mach.