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Ngày tải lên: 12/08/2014, 18:20

... cultured on polyacrylamide gels with similar chemical properties but different stiffness generated stronger traction forces on the stiffer gels than on the softer ones [Lo, 2000] A significant finding ... contractile than on stiff gels, and if they are less contractile, then their adhesions need not be as strong This is consistent with a reduced adhesion strength as measured by reduced forces to peel...

Ngày tải lên: 28/09/2015, 13:28

... CD8+ T cell proliferation (Fig 1d) Interestingly, when adding 3a-G1, CFSE diluted events were strongly reduced within both T cell subsets indicating that although CD8+ T cells are not a major ... purified CD4+ T cells stimulated by anti-CD3/CD28 micro-beads revealed that proliferation was still strongly inhibited 3.6% ± 0.2% compared to 67.5% ± 5.9% in the control conditions (Fig 4) Performing...

Ngày tải lên: 18/06/2014, 15:20

... NIEHS/NTP (NTP-90-105/NTP-90-105A) (and report supplement), Order No.PB91-137570 1990 Price CJ, Strong PL, Marr MC, Myers CB and Murray FJ: Developmental toxicity NOAEL and postnatal recovery in...

Ngày tải lên: 20/06/2014, 00:20

... between donors Although on average Dexamethasone increased cell proliferation, its effect varied strongly between donors to the extent that it significantly decreased osteoblast proliferation in ... Although our average findings concur with this general picture, we also found the effects were strongly donor-dependent Most in vitro studies would see donordependency as a "nuisance factor" and ... Dexamethasone on cell proliferation of normal human trabecular bone-derived cells (NHBCs) also found strongly donor-dependent effect of this agent [33] Genetic polymorphism has been reported as a cause...

Ngày tải lên: 20/06/2014, 01:20

... shown in Fig 9, if there was only daunorubicin in the cell system, the excited fluorescence was not strong However, when the combination of daunorubicin and ZnO nanoparticles was injected into the...

Ngày tải lên: 21/06/2014, 18:20

Ngày tải lên: 11/08/2014, 03:20

Ngày tải lên: 11/08/2014, 06:23

Ngày tải lên: 12/08/2014, 11:23

Ngày tải lên: 12/08/2014, 15:21

... Allergy 2010, 8:11 http://www.clinicalmolecularallergy.com/content/8/1/11 14 Prescott SL, King B, Strong TL, Holt PG: The value of perinatal immune responses in predicting allergic disease at years...

Ngày tải lên: 13/08/2014, 13:22

... all, genes by Myc, and abolish transformation by Myc (Nikiforov et al 2002) Together, the data strongly support the view that TRRAP-dependent stimulation of local histone acetylation is a key ... a K63-linked poly-ubiquitin chain required for transcriptional activation by Myc Both findings strongly suggest that ubiquitination of Myc is not solely used to control Myc levels, but to control ... stimulation of proliferation by Myc in keratinocytes (Gebhardt et al 2005) Taken together, the data strongly suggest that regulation of Cdk4 function is a critical function of Myc in tumorigenesis...

Ngày tải lên: 25/10/2013, 21:20

Ngày tải lên: 19/02/2014, 13:20

... MAPK/ERK cascade, including ERK1/2, normally promotes cell proliferation, as indicated by the strong correlation between ERK1/2 activation and both DNA synthesis and PCNA expression [22,23] Here, ... addition, the finding that PMA-induced MEK1/2 activation was completely prevented by the drug treatment strongly suggests that NAMIA-mediated inhibition of ERK1/2 phosphorylation may be lying upstream ... finding that, in serum-free cells PD98059 completely suppressed PMA-induced c-myc mRNA expression, strongly indicates a crucial role of the Ras/Raf/MEK/ ERK pathway in modulating phorbol ester-activated...

Ngày tải lên: 21/02/2014, 01:21

Ngày tải lên: 07/03/2014, 00:20

... cell types compared to vehicle-treated cells (Fig 1B) However, the mitotic arrest was found to be stronger in HeLa cells than in MCF-7 cells (Fig 1B) After 24 h of incubation with 0.2 lm and 0.5 ... concentrations (1 lm and lm) of rotenone, the interphase microtubule network of the MCF-7 cells was strongly depolymerized (Fig 3A) In HeLa cells, the interphase microtubules remained mostly unaffected ... assembly occurred in the presence of 20 ± 3.4 lm rotenone (data not shown) Furthermore, rotenone strongly suppressed the GTP hydrolysis rate of tubulin assembly (Fig 8) Binding of rotenone to tubulin...

Ngày tải lên: 07/03/2014, 05:20

... organogenesis, hibernation and insulin-resistant obesity More recently, we found that cartducin is strongly expressed in both the chondrogenic cell lineage in the sclerotome and proliferating chondrocytes...

Ngày tải lên: 16/03/2014, 13:20

... This novel observation is clearly inconsistent with a general effect on mitochondrial activity Strong support for this view is also provided by the fact that growth inhibition is dissociated from...

Ngày tải lên: 17/03/2014, 09:20

Ngày tải lên: 22/03/2014, 17:20

Ngày tải lên: 30/03/2014, 13:20