therapeutic implication for parkinson s disease and other motor disorders
Tài liệu THERAPEUTICS of PARKINSON’S DISEASE and OTHER MOVEMENT DISORDERS docx
... THERAPEUTICS of PARKINSON S DISEASE and OTHER MOVEMENT DISORDERS Therapeutics of Parkinson s Disease and Other Movement Disorders Edited by Mark Hallett and Werner Poewe © 2008 John Wiley & Sons, ... degradation and PARKINSON S DISEASE AND PARKINSONISM PARKINSON S DISESASE Sporadic Autosomal Dominant SYN LRRK2 UCH-L1 GENES TOXIN Autosomal Recessive AGING PARKIN DJ-1 Protein O abnormal autophagy UPS ... Therapeutics of Parkinson s Disease and Other Movement Disorders Edited by Mark Hallett and Werner Poewe © 2008 John Wiley & Sons, Ltd ISBN: 978-0-470-06648-5 The Etiopathogenesis of Parkinson s Disease: ...
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Surgical Treatment of Parkinson’s Disease and Other Movement Disorders pot
... neurons Reports of movement disorders secondary to extrastriatal pathology should therefore come as no surprise 3.1 Parkinson s Disease Early idiopathic Parkinson s disease (PD) is a well-circumscribed ... interpretations of the different movement disorders, because of the existence of movement disorders such as Huntington s disease (HD) or dystonia, which seem to cross the boundary between these diseases ... Richard Scott, and Tipu Z Aziz Subthalamotomy for Parkinson s Disease 145 Steven S Gill, Nikunj K Patel, and Peter Heywood Thalamic Deep Brain Stimulation for Parkinson s Disease and Essential...
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PARKINSON''''S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN potx
... PARKINSON' S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN CURRENT CLINICAL PRACTICE Parkinson s Disease and Movement Disorders: Diagnosis and ... patients with movement disorders The text is organized into five sections: basic diagnostic principles, Parkinson s disease, other parkinsonian disorders, hyperkinetic movement disorders, and other ... disorder is associated with other signs, such as parkinsonism or ataxia Most hyperkinetic disorders arise outside conscious awareness and are entirely involuntary Some, however, are responses...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx
... nervous system neurons A recent study analyzed the enteric nervous system in PD and found that both Meissner s and Auerbach s plexuses were affected already in early stages of disease and terminal ... in human tissues, and that this has implications for how to interpret the role of the studied enzymes in health and disease Results The distribution and relative intensity of expression of the ... components Signal intensities were scored using a semiquantitative scale with five steps (–,+),+,++ and +++) Scores were based on several sections ⁄ animal and several animals ⁄ observation and confirmed...
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Báo cáo y học: "Cardiac surgery in a patient with retroperitoneal fibrosis and heart valvulopathy, both due to pergolide medication for Parkinson''''s disease" pps
... in Parkinson' s disease: a case-control study Neurology 2006, 67:1225-29 Camp GV, Flamez A, Cosyns B, Goldstein J, Perdaens C, Schoors D: Heart valvular disease in patients with Parkinson' s disease ... dopamine agonists (0%) or controls (5.6%) New evidence from population studies comparing patients with Parkinson' s disease and non-parkinsonian controls suggests that the risk of substantial valve ... the past months His symptoms included exerciseinduced dyspnea and paroxysmal nocturnal dyspea (NYHA III) From his past medical history we noted Parkinson' s disease diagnosed three years ago Pergolide...
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Tài liệu Parkinson’s Disease and Related Disorders docx
... L.: Sleep disturbances and excessive daytime sleepiness in Parkinson disease: an overview Arnulf, I.: Sleep and wakefulness disturbances in Parkinson s disease ... outstanding scientists and clinicians, Toshiharu Nagatsu, Yoshikuni Mizuno, Japan (Award of the WFN Research Group on Parkinsonism and Related Disorders) , Saskia Biskup, Germany and Andrew B Singleton, ... Disease and Parkinsonism seen at the Columbia-Presbyterian Medical Center from 1949 to 1964 Nearly 85% had classic Parkinson s Disease and 13% had post-encephalitic associated Parkinsonism This...
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Tài liệu Alzheimer’s Disease and Other Dementias doc
... Psychological Disorders Alzheimer s Disease and Other Dementias Psychological Disorders Addiction Alzheimer s Disease and Other Dementias Anxiety Disorders Child Abuse and Stress Disorders Depression ... feelings, vision problems, etc Degenerative diseases like Huntington s disease or other rare, usually genetically transmitted diseases may also cause dementia in adolescents This illness destroys ... blood vessels that supply the heart muscle with oxygen and nutrients narrow These diseases can cause strokes and heart disease (heart attacks) in the elderly The most common causes of illness and...
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The Handbook of Alzheimer’s Disease and Other Dementias doc
... Medical School Massachusetts Alzheimer s Disease Research Center Massachusetts General Hospital, Boston, MA USA Preface This book provides a comprehensive review of Alzheimer s disease and other ... lipofuscinosis Multiple infarct dementia “Binswanger s disease “Small vessel ischemic disease CADASIL Schizophrenia Dementia syndrome of depression Bipolar disorder Malingering Obsessive compulsive ... dementias Vascular dementias Psychiatric disorders Important examples Prion diseases, syphilis, Lyme disease, chronic meningidites, PML, HIV, Whipple s disease, hydrocephalus Primary or metastatic...
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An Atlas of PARKINSON’S DISEASE AND RELATED DISORDERS pdf
... ISBN 1-85070-943-2 Extrapyramidal disorders Atlases Parkinsonism Atlases Movement disorders Atlases I Title II Series [DNLM: Parkinson Disease atlases Basal Ganglia Diseases atlases Movement Disorders ... Parkinson s disease ©2004 CRC Press LLC Figure 11 Posture in later-stage Parkinson s disease Figure 12 Parkinson s disease: Impaired fist clenching Figure 13 Parkinson s disease: Tremor illustrated ... in Spain by T.G Hostench, S. A Contents Foreword Preface Acknowledgements Section A Review of Parkinson s Disease and Related Disorders Section Parkinson s Disease and Related Disorders Illustrated...
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An Illustrated Pocketbook of Parkinson''''s Disease and Related Disorders pot
... Parkinson s disease AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 12 Parkinson s disease: impaired fist clenching 11 12 AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 13 Parkinson s ... PARKINSON S DISEASE Figure 16 Parkinson s disease: dystonic posturing of the big toe secondary to dopa therapy 15 16 AN ILLUSTRATED POCKETBOOK OF PARKINSON S DISEASE Figure 17 Parkinson s disease: ... RD, Bakay RA Neurosurgical horizons in Parkinson s disease Neurology 1993;43:l–7 Parkinson' s disease Any discussion of the clinical characteristics of Parkinson s disease must take into account...
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báo cáo hóa học: " Gait dynamics in mouse models of Parkinson''''s disease and Huntington''''s disease" doc
... used for image analyses The treadmill belt was wiped clean between studies if necessary Statistics Data are presented as means ± SE ANOVA was used to test for statistical differences among saline-treated, ... SOD1 G93A and wild-type control mice at age ~8 weeks, ~10 weeks, ~12 weeks, and ~13 weeks Discussion Gait disturbances are characteristic of Parkinson' s disease, Huntington 's disease, and amyotrophic ... neurons [63] Dengler et al surmised that new motor unit sprouting and resulting increases of twitch force could compensate for the loss of motor neurons in patients with early stages of ALS [64]...
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TOWARDS NEW THERAPIES FOR PARKINSON''''S DISEASE doc
... Previous models have dealt with disease progression in different ways: some have used UPDRS scores as the basis for measuring disease progression, whilst others have used the Hoehn and Yahr scale ... care costs Relationship between increasing cost of care and severity of the disease as measured by Hoehn and Yahr stage was proven to be 24 Towards New Therapies for Parkinson' s Disease statistically ... outcome was not correlated with H&Y staging or disease duration [18] Controversial Issues in Deep Brain Stimulation in Parkinson' s Disease Levodopa (LD) responsiveness LD responsiveness, as measured...
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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 5 pot
... Figure 14 Positive glabellar tap Persistent blinking is a feature of Parkinson s disease, but is also seen in Alzheimer s disease Figure 15 6-[18F]-fluorodopa–PET scan appearance in a normal subject ... cells (astrocytes and macrophages) Debris and a few vascular channels can be seen (Luxol fast blue–H & E) Figure 24 CT of a patient with a Parkinsonian syndrome shows multiple lacunar infarcts ... Histological sections from Parkinson' s disease with dementia showing cortical Lewy bodies stained with ubiquitin (immunochemistry preparation, left; silver impregnation, right) Figure 28 Histology...
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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 6 ppt
... normal subject (left) compared with that in Parkinson' s disease (middle) and in progressive supranuclear palsy (right) (11C-raclopride is a selective reversible antagonist of D2 receptors) Figure ... degeneration shows atrophy of the putamen with rarefaction and gliosis (H & E) Figure 35 Transverse section of midbrain in striatonigral degeneration shows pallor of the substantia nigra ©2004 CRC Press ... (lower) basis pontis secondary to olivopontocerebellar atrophy in multiple system atrophy Figure 38 Histological sections of basis pontis (arrowed) show the normal complement of pontine neurons in...
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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 7 pot
... 45 Histological section of cerebral cortex in corticobasal degeneration shows severe gliosis and an achromatic neuron (H & E) Figure 46 Histological sections of cerebral cortex showing swollen ... proved responsive to botulinum toxin ©2004 CRC Press LLC Figure 55 Abnormal neck posture in a patient with spasmodic torticollis Figure 56 Mechanisms of actions of various botulinum toxins (BTX) ... the wrist and the abducted posture of the little finger ©2004 CRC Press LLC A B C Figure 49 This patient with corticobasal degeneration shows ideomotor apraxia of the left hand When asked to...
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PARKINSON’S DISEASE AND RELATED DISORDERS - PART 8 ppt
... Histology in Wilson 's disease shows atrophy and rarefaction of the putamen (black arrows) Loss of myelin bundles in the putamen contrasts with the more normal appearances in the globus pallidus ... Huntington 's disease is accompanied by DNA gels (lower) which indicate trinucleotide repeats of between 40 and 52 ©2004 CRC Press LLC Figure 68 Coronal section of brain in Huntington 's disease shows symmetrical ... fast blue) Figure 63 Histology of brain in Wilson 's disease shows a Bergmann type astrocyte within an atrophic putamen (H & E) ©2004 CRC Press LLC Figure 64 Histology of brain in Wilson 's disease...
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