the thumb was not amputated the fingers are replantable the small and long fingers are easy to identify but the index and ring fingers are difficult to tell apart because they ar
Báo cáo y học: "HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex" pdf
... for others such as V19M and C23W, that are strong NF-κB activators, the senescence phenotype was significantly attenuated These results support the notion that the Tax-induced cell cycle arrest/rapid ... (Tax-IRS) and increase in p21CIP1/WAF 1and p27KIP 1levels are causally related and not involve directly either the CREB/CBP/p300 or the IKK/NF-κB pathway Whether the IKK/NF-κB pathway may share a ... assays and the extent of I-κB degradation and p100 processing These mutants are nevertheless impaired in elevating p21CIP1/WAF 1and p27KIP 1levels These results support the notion that the NF-κB...
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Báo cáo y học: "otspots of homologous recombination in the human genome: not all homologous sequences are equal" ppsx
... primate species [11], and in some cases hotspots are characterized by signatures of concerted evolution [7], whereby duplicated sequences are more similar to one another than to their orthologs in ... normal distribution within the narrow hotspot; they have no obvious sequence similarities with one another, and coincide with gene-conversion hotspots [4] The location of AHR hotspots is not conserved ... hotspots, common features shared among NAHR hotspots include clustering within small regions (under kb), no obvious sequence similarities with one another, and coincidence with apparent gene conversion...
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Tài liệu The Internal Revenue Service Is Not Adequately Protecting Taxpayer Data on Laptop Computers and Other Portable Electronic Media Devices docx
... authentic, but the accuracy of the information could not be independently verified Area Offices are located throughout the United States; they serve as the coordination point for and assist the ... account names and passwords to the computer and various systems to which the employee has access on a piece of paper that was taped to the laptop computer The IRS requires employees to safeguard passwords ... personal information belonging to as many as 17,000 current and former employees of the Long Island Railroad The IRS uses the same storage company to store backup data for some Area Offices.1 • Also...
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Báo cáo khoa học: The activation of gelsolin by low pH The calcium latch is sensitive to calcium but not pH docx
... compares to calcium-induced conformational change and if there are differences in the properties of pH and calcium activated gelsolin Also it is necessary to determine if low pH affects the various ... )15% and )17% were calculated for 159–193 and 203–225 peptides, respectively The apparent Kd (Table 1) are similar to those obtained at pH 7.5 It appears that the interaction between G2 and G4–6 ... 405 nm and L the ligand concentration, by using the CURVE FIT software developed by K Raner, Mt Waverley, Victoria, Australia Details on the different experimental conditions are given in the figure...
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Báo cáo y học: " A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus" pptx
... gel and wet gel was exposed to autoradiograph (Figure 5) We compared the length of the largest fragment obtained during single cycle of processive cDNA synthesis by three RTs The largest cDNA band ... a-phosphate and the ε-amino group of Lys65 donates hydrogen bonds to the g-phosphate These events lead to the finger closure and trapping of the template strand due to the interaction of L74 with the ... K65R and L74V and the rare occurrence of K65R+L74V on the same HIV genome [6,27] may be related to the observed attenuation of the virus in the presence of these mutations [5,7,12,15] Comparison...
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Báo cáo y học: " The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro" doc
... cells was reported to greatly impair both the early and late steps of viral reverse transcription To further define the structural determinants of the HIV-1 RTHuR interaction at the atomic level and ... scattering (Fig 2B) Both proteins were found to exist as monomers in solution and the molecular masses of NusA-HuR and NusARRM were determined as 82.2 and 68.9 kDa, respectively These values are ... lane shows the flowthrough fraction of the glutathione sepharose column, lane contains molecular weight markers and lane is the eluate during the column wash Purified GST-HuR eluted from the glutathione...
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Are difficult experiences valuable lessons for the futur1
... has discussed above, I agree with the title statement not only because the seemingly difficult experience can make us adapt to the future but also because it can bring us health ... www.word-reader.com interesting program on the TV, so I did not prepare for it When I know that I failed in the test, I could not believe that From then on, I know that what you get depend on...
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Tài liệu The Invariance of the Index of Elliptic Operators, elliptic operators pdf
... = H0 , then they are bounded in Hk for any k ∈ N, and in particular they are bounded in Hs for some s > But then by the Rellich Lemma, the infinite sequence is compact in L2 , and therefore contains ... Ordway, and Benjamin Stephens for the help and support, mathematical or other, that they have provided during my tenure at Harvard in general, and during the researching and writing of this thesis ... close to the old, then the index of any given elliptic operator is preserved 3.3 Proof of the Invariance of the Index We have finally developed the machinery necessary to prove the main Theorem Theorem...
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Tài liệu Impact Evaluation Of Small And Medium Enterprise Programs In Latin America And The Caribbean pptx
... whether they had participated in it in the past and, if so, in what year; (iv) the monetary value of the incentive; and (v) how they rated the importance of the program for their business.18 The ... Evaluation Chile – Small and Medium Enterprise – Monitoring and Evaluation Colombia – Small and Medium Enterprise – Monitoring and Evaluation Peru – Small and Medium Enterprise – Monitoring and Evaluation ... Chile Small and Medium Enterprise - Monitoring and Evaluation – Colombia Small and Medium Enterprise - Monitoring and Evaluation – Peru Mexico – Small and Medium Enterprise – Monitoring and Evaluation...
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Tài liệu Effect modification of air pollution on Urinary 8-Hydroxy-2’-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions ppt
... Deletion 145 (48.82) *The sum of the subjects in each genotype may not add up to the total number of subjects due to missing genotyping data Missing genotyping is due to a variable number of samples ... distribution samples and the data generating distribution P Samples are drawn at random with replacement from the observed data The program generates B bootstrap samples from hypotheses M and obtains ... Affairs Boston Healthcare System and the Department of Medicine, Boston University School of Medicine, Boston, MA, USA Environmental and Occupational Medicine and Epidemiology Program, Department...
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Tài liệu EFFECTIVE POLICIES FOR SMALL BUSINESS: A GUIDE FOR THE POLICY REVIEW PROCESS AND STRATEGIC PLANS FOR MICRO, SMALL AND MEDIUM ENTERPRISE DEVELOPMENT pptx
... country to country Definitions are useful: • • • • In the preparation of statistics and the monitoring of the health of the sector over time; In benchmarking against other economies and between ... necessary, fair and affordable and simple to understand and administer taking particular account of the needs of small businesses and ordinary people’ Specific issues are studied by sub-groups of the ... that the benefits of moving into the formal sector are clearly identified and promoted Examples of this include legislation regarding the security and transfer of land and property and measures to...
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Tài liệu Guide to Using International Standards on Auditing in the Audits of Small- and Medium- sized Entities pptx
... transactions are downloaded daily from the website and sales orders are prepared and forwarded to the production department Human Resources All hiring decisions are made by Dameer and Suraj Like his father, ... downloaded from the website Details of the items ordered are prepared and given to the production department An invoice is prepared at the same time and recorded into revenue since the item has ... Suraj and Dameer are never too far away from the production process and so they share the task of supervising the staff Jawad Kassab (a cousin of Suraj) is in charge of the finance function and...
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Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... in the cytoplasm Precedents exist for all three possibilities The ICDs of proteins such as Notch and APP are notoriously difficult to detect in nuclei, as they represent a small percentage of the ... form a complex with the nuclear adaptor Fe65 and the histone acetyltransferase Tip60 in order to target to the nucleus [61,62] Other ICDs function exclusively in the cytoplasm The adhesion protein ... the whole protein and they are very labile, so it remains possible that we are simply unable to detect the small amount of ICD that might localize to the nucleus constitutively The APP ICD must...
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Tài liệu Báo cáo khoa học: "Using adaptor grammars to identify synergies in the unsupervised acquisition of linguistic structure" docx
... symbol are shown tor grammars using regular expressions for clarity, but since our implementation does not handle regular expressions in rules, in the grammars actually used by the program they are ... “show” and tell ), but they lower the word f-score considerably 3.6 Collocation syllable adaptor grammar The collocation syllable adaptor grammar is the same as the unigram syllable adaptor grammar ... subtree in the parses of the other strings in the training corpus A final accept-reject step corrects for the difference in the probability of the sampled tree under the adaptor grammar and the PCFG...
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Tài liệu Báo cáo Y học: The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B ppt
... activity as compared to GS itself and thus a much lower therapeutic index [5] These results are important because they establish that it is possible to dissociate the antimicrobial and hemolytic ... of the (Lb¢) to the (Pb¢) phase and the main transition from the conversion of the Pb¢ to the La phase For a more detailed discussion of the thermotropic phase behavior of Myr2Gro-PGro and other ... inhibit the growth of A laidlawii B These are the phospholipid bilayer/water partition coefficient, the localization and orientation of the peptide within the phospholipid bilayer, and the degree to...
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The Role of Small and Large Businesses in Economic Development doc
... Small businesses are potent job creators, but so are large businesses The attribution of the bulk of net job creation to small businesses arises largely from relatively large job losses at large ... wisdom— that small businesses are the cornerstone of innovative activity and that large firms are too big and bureaucratic to make significant innovations— is false Both small and large firms make ... dominate the market For the most part, these firms not compete with one another on the basis of price, but rather on the basis of quality and product differentiation Given this market structure, large...
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The importance of project management in small- and medium-sized enterprises (SMEs) for the development of new products through E-collaboration docx
... each area, the interaction of the areas with the key project management processes described earlier, available management tools and techniques for each area, and input and outputs of each area ... of these interviews was to understand the companies’ process for collaboration among four departments into product and process development and to elicit insights into how they had overcome barriers ... 50 to h The participants were given an explanation regarding the purpose of the feedback, the purpose of the conceptual model, some background of the research that lead to the development of the...
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corporate social responsibility strategies for sustainable development for small and medium enterprises in the village of bac ninh province, vietnam
... unit to be effective The mission of the enterprises in the villages: - To maintain the traditional products in the marketplace - To maintain the prestige of the business to the customer - To develop ... (payment arrears extended), the closed status less objective and responsibility of the investors are not regulated clear, in fact the advantage is always in favor of the customers, investors, causing ... synthesis of theory, strategy and business development at the small and medium enterprises in the village of BacNinh province, Vietnam The research applied the theories and models to analyze and...
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A Complete Guide for All Ages: Easy to understand information from the nation’s leaders in women’s health doc
... nutrients to all the cells It also picks up carbon dioxide and waste products from the cells Arteries are the blood vessels that carry oxygen-rich blood away from the heart to all the parts of the ... l are too high are borderline high have been steadily increasing for the last several years but are still in the normal range Cigarette smoking The more you smoke, the higher your risk of heart ... minutes if not treated quickly Cardiac Arrest A sudden cardiac arrest is not the same as a heart attack In a heart attack, the heart usually does not suddenly stop beating But sudden cardiac arrest...
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