the index model and the single factor apt
Chapter 6 The Single Index Model and Bivariate Regression
... well diversi& portfolio ed The single index model can be expanded to capture multiple factors The single index model then takes the form a k−variable linear regression model Rit = αi + β i,1 F1t ... 2,M and εpt = x1 ε1t + x2 ε2t Hence, the single index model will hold for the return on the portfolio where the parameters of the single index model are weighted averages of the parameters of the ... denotes the j th systematic factorm, β i,j denotes asset i0 s loading on the j th factor and εit denotes the random component independent of all of the systematic factors The single index model...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... localized in the UTRs of the transcript and the trans-acting factors (RNA-binding proteins and noncoding regulatory RNAs) that bind to these sequences Among the best studied regulatory sequences, the ... formation and ⁄ or remodelling: the heterogenous nuclear ribonucleoprotein (hnRNP) family, the DEAD ⁄ H box RNA helicases and the serine-arginine (SR) proteins We then investigated the subcellular ... proteins corresponding to the transcription factor UBF1, the ribonucleoprotein hnRNP M, the RNA helicases RHII ⁄ Gu ⁄ DDX21 and p68 ⁄ DDX5, and the SR protein ASF ⁄ SF2 (Fig 1C) The interactions of...
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Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx
... where the authors have identified the reverse products and shown that the CMP activation of the reverse of synthesis is by a different mechanism from base exchange [20] Further analysis of the products ... ACKNOWLEDGEMENTS The authors thank A Zachowski, E Ruelland and A Jolliot-Croquin for helpful discussions and advice This project was funded by the French Ministries of Research and Education via CNRS and the ... obtained at mM EDTA and plotted as a function of the free Mn2+ concentration (Fig 2B) The data show that synthesis and exchange with or without CMP behave in the same way according to the concentration...
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Operation of the Air Pollution Index (API), the Air Quality Index (AQI) and the Air Quality Advisory pdf
... taken as the Air Quality Index One of the AQI sub -index values may be the API sub -index If the API sub -index is the highest of the sub-indices, then the API is the basis of the AQI Adverse Meteorological ... Ontario the Air Pollution Index and the Air Quality Index This guideline outlines the objectives of these two indices and describes actions the Ministry shall take in connection with them to ... objectives and enforcement mechanisms Authority for the Air Pollution Index, and for the control measures associated with it, is contained in O.Reg 346, S.4 The Air Quality Index is produced and disseminated...
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Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt
... vitro and in silico analysis of the data The plot shows nuclear NF-jB oscillation in the original model and in the updated model with newly measured kr1, ka1 and kd1 for IKKIjBa complex (D) In the ... original model kr1 (kcat) for IKKIjBa was 4.07 ã 10)3 s)1 In the updated model, the original values are replaced with 1.13 ã 10)2 s)1 (D) (E) shows a plot of the original and the updated model with the ... binding GST-IjBa in the presence and absence of ATP, and the value of a indicates whether the binding of one substrate (ATP) affects the afnity of the enzyme for the other substrate (GST-IjBa) [59]...
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Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
... d), for h, and then washed and probed with biotin-curdlan (cur), as described in the Materials and methods (1fi3)-b-D-glucan-binding proteins and was therefore termed GLUBPp_SUBDO The protein ... within the middle segment of the a-, b- and c-chains Hence, no further classification of the sponge protein to any of the three vertebrate chains can be made In the sponge sequence, besides the first ... together with the techylectins from the horseshoe crab, Tachypleus tridentatus [20] (AB024737.1 and AB024738.1), and the angiopoietins from mammals, e.g humans (O15123), form the second branch The...
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Báo cáo khoa học: Identification and characterization of four novel peptide motifs that recognize distinct regions of the transcription factor CP2 doc
... whether PKC-d and CKII-a can also alter the effect of YY1 on CP2 We also demonstrated that, unlike the HXPR and ASR motifs, PHL and PXHXH motifs bind to the N- and C-terminal parts of the Elf-1 domain ... and ETS-1 have two motifs The two protein kinases, PKC-d and CKII-a, have both PHL and ASR motifs, whereas ETS-1 has PHL and HXPR TFIIE-a contains a PXHXH motif Among these proteins, YY1 is the ... whether these two motifs recognize the same sequences in CP2, and thus further study is required to dissect this region If the two motifs bind to overlapping, or the same, residues, the question...
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Báo cáo khoa học: Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor doc
... recruits the histone acetyltransferase p300 to the b-globin promoter and this activity increases the accessibility for transcription factors TFII-I recruits HDAC3 and the PRC2 complex, which render the ... LCR element HS2 and to the b-globin gene promoter [20] At the same time, we observed a reduction in the recruitment of CBP and p300 to these sites To examine in more detail whether USF recruits ... between USF and p300 This suggests that the recruitment of CBP ⁄ p300 to the LCR, at least in K562 cells, is mediated by proteins other than USF, and potential candidates are GATA-1 and NF-E2,...
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Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot
... p65 are found in the oocyte, pre-implantation embryos and in the testis On the other hand, p50 ⁄ Nf-jb1 EST sequences are found in the oocyte and in the testis but not in any of the pre-implantation ... be the major NF-jB proteins expressed specifically in the testis [21–23] Expression of p50 and p65 was confirmed in the testis and established in the TM3 and TM4 testicular cell lines by RT-PCR and ... of the p65 and p50 NF-jB subunit proteins in testicular cells (A) RT-PCR detection of p50 and p65 transcripts in the testis (Te) and in TM3 and TM4 cells (B) Western blot analysis of the p50 and...
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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf
... the sequence The consensus site for calpain cleavage and the positions of the three imperfect cleavage sequences identified in CARP are shown at the bottom The truncated constructs (DNter1-4 and ... and 71 Considering the location of the N-terminal extremity of DNter2 on the structure of CARP and the presence of the potential cleavage sites, we identified the localization of the cleavage site ... in the subcellular compartments Regulation of CARP by calpain obtained from the muscle of the mice injected with pYFP-CARP-CFP-HIS confirms the presence of the protein in the nucleus and on the...
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Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf
... platelets, namely the mAb to GPIb, 6D1, and the mAb to aIIbb3, LJ-CP8 Taken together, these data are reflective of the ability of saratin to both block VWF–collagen binding and to inhibit a2b1–collagen ... Importantly, the presence of saratin reduced both the percentage of surface coverage and the amount of thrombi formed to a similar level as observed in the presence of the GPIb and a2b1 antagonists ... Structural studies on the VWF A3 domain showed that it assumes the same fold as the binding site for collagen on the a2b1 integrin, namely the homologous integrin a2 I domain [26] The present study...
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Generations Model and the Pension System
... arranging that the young care for the old, and transfer part of their labor income to the retired generation The transfers which the young have to pay are then more than offset by the fact that they don’t ... to the number of young individuals) A is the technology Download free eBooks at bookboon.com The overlapping generations model Generations Model and the Pension System parameter and grows at the ... at bookboon.com The overlapping generations model Generations Model and the Pension System The overlapping generations model The households Individuals live for two periods In the beginning of...
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The Qverlapping Generations Model and Pension
... Introduction The overlapping generations model The Overlapping Generations Model and the Pension System The overlapping generations model The households Individuals live for two periods In the beginning ... t is their consumption minus their income Their consumption is equal to their financial wealth, which is equal to the value of the firms Their income is the capital income on the shares of the firms ... arranging that the young care for the old, and transfer part of their labor income to the retired generation The transfers which the young have to pay are then more than offset by the fact that they don’t...
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The Relational Data Model and Relational Database Constraints
... management comes from the formal foundation provided by the theory of relations We review the essentials of the relational approach in this chapter Relational Model Concepts The model was first ... Relational Model Concepts The relational Model of Data is based on the concept of a Relation A Relation is a mathematical concept based on the ideas of sets The strength of the relational approach ... Statement of the constraint The value in the foreign key column (or columns) FK of the the referencing relation R1 can be either: (1) a value of an existing primary key value of the corresponding...
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báo cáo hóa học: " The Locomotor Capabilities Index; validity and reliability of the Swedish version in adults with lower limb amputation" ppt
... differ in their locomotor capabilities and high correlations between the LCI and the TUG test and between the LCI and the EQ-5D The reliability tests showed good internal consistency and the test-retest ... 0.66 and for the advanced was 0.92 (Table 4) For the bilateral amputees the ICC for the total LCI was 0.90, for the basic 0.93 and for the advanced 0.59 and the mean score difference between the ... prosthesis may differ in how much they use the prosthesis and in the type of activities they can perform with their prosthesis [7] Procedure of translation The procedure of cross-cultural adaptation...
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báo cáo hóa học:" Japanese version of the Dermatology Life Quality Index: validity and reliability in patients with acne" potx
... focus on the burden of a specific disease The questionnaire together with the changes described above was then submitted to the authors of the original questionnaire, and they approved the Japanese ... interpreted the data, edited this article for language and commented on the paper Finlay AY and Fukuhara S contributed in the concept and design of this study, interpretation of the data, and revising the ... was provided to the subject during the outpatient examination After the study was explained, the consent of the subject to participate in the study was obtained The subjects were then asked to...
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Báo cáo hóa học: " Research Article Effects of Carrier Frequency Offset, Timing Offset, and Channel Spread Factor on the Performance of Hexagonal Multicarrier Modulation Systems" doc
... Vz) is the modulation pulse associated with cz and z = [m, n]T , m ∈ M, n ∈ N , while m and n can be regarded as the generalized time index and subcarrier index, respectively Moreover, M and N ... on the channel spread factor of DD channel The maximum SINR timing decreases with the product τrms fd increasing, and the timing offset Δt increases as the product τrms fd increases, that is, there ... combating the DD channel, and there is an SINR gap between HMM and CP-OFDM about ∼ dB at SNR = 30 dB In Figure 3, we fixed Δt to the maximum SINR timing and the product τrms fd to 0.02, 0.01, and 0.005...
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Báo cáo hóa học: " Characterization and Optical Properties of the Single Crystalline SnS Nanowire Arrays" pot
... that the SnS nanowires have high absorption in the range of ultraviolet, and the absorption coefficient is above the 70% The absorption reduces rapidly with the increase in the wavelength, and the ... determine the energy band gap, Eg, and the type of optical transition responsible for this intense optical absorption, and the absorption spectrum was analyzed using the equation for the near-edge ... that the alumina matrix is dissolved completely The nanostructure of the SnS nanowires was further investigated with SAED The SAED pattern (Fig 3c) taken from a single nanowire, indicates that the...
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Báo cáo hóa học: " Stretching and immobilization of DNA for studies of protein–DNA interactions at the single-molecule level" ppt
... of the DNA; then the DNA molecule is stretched out by the force exerted on the rest of the DNA by the receding meniscus; and finally the other end also sticks to the substrate as it dries The ... between ssDNA and dsDNA The stretching force is increased to 50 pN to separate the newly synthesized strand from the template strand by destabilizing the DNA (B) Comparison of the elasticity ... during the synthesis and show a decrease in the replication rate when the force exceeds pN The decrease in the replication rate is attributed to the work that DNAP has to perform against the external...
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Báo cáo hóa học: " Review Article Bit and Power Allocation in Constrained Multicarrier Systems: The Single-User Case" potx
... the channel frequency response, Ni is the noise power, and Γ is the SNR gap expressing the loss, in terms of SNR, between the actual rate bi conveyed by the used transmission scheme and the theoretical ... survey on the bit and power loading in constrained multicarrier systems and at reviewing the most popular results on the loading algorithms for the RM and MM problems We examine the singleuser ... and therefore OFDM systems usually employ the same constellation in all carriers On the other hand, the wireline channel is treated either as almost constant or as slow time-varying, and therefore...
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