... depicted in Fig The meaning of the abbreviations used inthe scheme, andthe numerical Ó FEBS 2004 values of the equilibrium constants of the reactions, are depicted in Table The scheme takes into ... phosphate pathway had to be reversed to maintain the target fluxes Then, the NADPH needed to drive the reactions of the oxidative pathway into a backwards direction andto form hexose phosphates ... solutions of the kinetic model, setting the maximal activities to 100%, 50% and 200% of the original value remain with respect tothe reactions connecting phosphoenolpyruvate with malate The flux-minimized...
... efforts [8] In addition to evaluating the concept of markedly abbreviating the time taken to provide effective training for the masses [13], recent investigations using sophisticated (but easy to apply) ... dramatic, in terms of both life-saving and ICU resources In summary, the use of AEDs by the average person may be considered one of the greatest advances in critical care medicine during the past ... ventilation, therapeutic hypothermia, and various intravenous pharmacological infusions [10,11] Therefore, with the rapid use of AEDs by random bystanders, the usual scenario of aggressive ICU care, invasive...
... positions and resulting in an unconscionable bargain The legal meaning want the auditor have to understanding the lawful meaning of the terms inthe definition The meaning of “misrepresentation” includes ... auditing suggest the following activities for internal auditors in order to enhance their active roleinthe financial reporting process and thus, their rolein prevention and detection financial ... willing to accept and are capable of doing to discover fraud according to their standards of auditing andthe fees collected for their services However, the auditors are to focus on fraud in the...
... fasciclin I domains in CLAP with selected proteins inthe protein database The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone of CLAP andthe Fas I domains ... C-terminus in an internal position, we infer that the other candidate, D306, is the target for GPI modification and site of C-terminus truncation In some systems, the addition of GPI tothe C-terminus ... inthe ER, although the bonds or motifs linking the two subunits have not been determined Modifications tothe predicted amino acid sequence of prepro-CLAP, including removal of N- and C-terminal...
... resolution After the peaks are identified, all data points can be assigned into these peaks according to their local maximum points inthe way that a data point belongs tothe same peak as its local ... by searching for the peaks inthe distribution, and all data points can be clustered into these peaks according tothe local maximums of each data point Assume that r1 , r3 , and r4 are the distances ... say b is the local maximum point of a Point a will belong tothe same peak as point b Similarly, point b belongs tothe same peak as its local maximum point c and point c belongs to peak Therefore,...
... sensitive and rapid tool for its quantification in activated sludge It would be suitable for routine monitoring or measurement of a large number of samples, and lead to better understanding of the ... logarithm of their starting copy number was constructed A typical linear regression line is shown in Figure The averages of R2 value andthe slope of the calibration line were 0.9998 and 3.3955, ... evaluated based on the melting curve andthe sequencing analysis Melting peaks of the PCR product from activated sludge and that from negative control are shown in Figure Inthe activated sludge...
... categorized into the correct domain was 47.9% (156/326) However, since all the test terms are inherently related tothe IT field, we focused solely on descriptions categorized into the computer domain In ... contents of the top 1,000 pages, the remaining pages were not used in our experiments Inthe following two sections, we explain the first and second experiments, respectively 5.2 Evaluating Encyclopedia ... and Development in Information Retrieval, pages 184–191 Philip Resnik 1999 Mining the Web for bilingual texts In Proceedings of the 37th Annual Meeting of the Association for Computational Linguistics,...
... hanashi-nandesu-kedo” are less likely to be the beginning of the inserted clause because inthe three cases the bunsetsu tothe immediate left depends on the target bunsetsu On the other hand, the ... bunsetsu “父から, chichi-kara” is the most likely to be the beginning since the bunsetsu toits immediate left “辺りは, atari-wa” depends on the bunsetsu tothe right of the inserted clause “田んぼだったんです, ... information Therefore, the global information is also used to detect the beginning of the clauses If the end of a clause is given, the bunsetsus tothe left of the clause should satisfy the two conditions...
... five Mandarin vowels [a], [i](yi), [u](wu), [e], and [o](wo) with four tones: the flat tone (tone 1), the rising tone (tone 2), the falling and rising tone (tone 3), andthe falling tone (tone ... that contains speech in one channel and noise inthe other channel Each of the test sets contains 16 instances of each of the 24 consonants, giving a total of 2688 tokens inthe combined test ... 5.93 The training material comes from male and female speakers and consists of 6664 clean tokens, after removing unusable tokens identified during postprocessing The tokens from the remaining speakers...
... construct the suitable Poincar´ operator P and give the e relation between T0 -periodic P C-mild solution andthe fixed point of P After showing the compactness of the Poincar´ operator P and obtaining ... fixed point theorem or Banach fixed point theorem However, the conditions for Horn fixed point theorem are not easy to be verified sometimes andthe conditions for Banach fixed point theorem are too ... result, P is a compact operator In order to use Leray-Schauder fixed pointed theorem to examine whether the operator P has a fixed point, we have to make assumptions H2.2 and H2.5 a little stronger...
... denoting the sample index corresponding tothe estimate of the preamble boundary Here, is the fractional part and m is the integer part such that their sum is the actual offset m + δ m is an even integer ... corresponding tothe sum inthe first term andthe inner sum inthe second term represent cyclic autocorrelation of the sequence a(i) for zero and (τ p) lags, respectively, for 2l = m Since a(i), ... quantity equal tothe delay of the dominant path We presented a method to estimate the shift inthe frame boundary caused by the dominant path We also examined the quality of the frequency offset...
... the proposed channel estimator allows to reduce the necessary length of the training sequence from 26 bits inthe GSM standard up to only bits, while performance is maintained very close tothe ... the results obtained with the proposed estimator using a training sequence of M = bits and those obtained with classical LS using a training sequence of M = 26 bits (the length standardized in ... the ML estimation problem that takes into account the deterministic symbols corresponding tothe training sequence andthe statistics of the unknown symbols These statistics can be obtained and...
... proteins are shared; and 9, whether there is a textmined interaction between the human proteins An NBC must be trained using positive and negative training data sets in order to determine the ... more of the proteins inthe hand-curated GBM pathway In this way we were able to extend the hand-curated pathway from 73 proteins and 187 interactions to 181 proteins and 768 interactions A total ... pathway using our FIs, projecting cancer candidate genes onto the FI network to reveal the patterns of the distribution of these genes inthe network, and utilizing network clustering results on cancer...
... SalI, and inserted into the EcoRI and XhoI sites of pVAX1 (Invitrogen) The cytomegalovirus (CMV) promoter was amplified by PCR using pCEP4 as the template The CMV promoter was inserted into the HindIII ... of the U6 promoter tothe BamHI site downstream of the terminating sequence, were sequenced and then inserted into the cloning site of the baculovirus transfer vectors pVL1392 and pVL1393 (BD Biosciences, ... in mammalian cells makes them attractive candidate vectors for in vitro gene therapy studies [14,15] These recombinant vectors contain compatible promoters and are highly effective in infecting...
... (Approx 55 h) in simulation time A B Figure The GSH/GSSG ratio of the prototype and expanded models The GSH/GSSG ratio of the prototype and expanded models The prototype model (A) andthe expanded model ... enzymes in glycolysis bind tothe Band III protein, an abundant membrane protein inthe human RBC [38-40] The interaction between glycolytic enzymes and Band III varies depending on the ratio ... of these enzymes was allowed to change according tothe ratio of GSH and GSSG The equations and parameters used are derived from the literature [17] The parameters and kinetic equations in the...
... inhibitor The points to note in this strategy are: (i) a competitive inhibitor of ICLs can serve the purpose; and (ii) the percentage inhibition of the ICDkinase and/ or proposed inactivator of ... binds only tothe enzyme-substrate complex, a decrease in enzyme-substrate complex concentration leads to a decrease in inhibitor binding, resulting in less inhibition The increase in efficiency ... appropriate for eliminating the pathogen The study highlights the difference between the inhibitor concentrations required in vitro andin vivo to inhibit the glyoxylate bypass pathway enzymes The advantage...
... of the total) were included inthe testing set, whereas the remaining 333 sires were inthe training set Predictions were calculated from the training set, andthe accuracy of predicting the ... Sires inthe training and testing sets had an average of 33 and 44 progeny, respectively Family size (half sibs) inthe training set ranged between and 284, with the mean and median being 32 and 17, ... assess the reliability of genome-assisted evaluation, two data sets (training and testing) were constructed The testing set included offspring from sires with records inthe training set Sires included...
... and Instance Extraction After gathering the formatted information inthe preprocessing step, we use an instance extractor together with a list of feature extractors to generate the instances and ... Preprocessing Preprocessing is the step to convert input texts into formatted information Users can integrate different tools in this step These tools are applied on the input texts to extract ... nouns in WordNet Their retrieval method maintained the stem-based index and adjusted the term weight in a document according toits sense matching result with the query They attributed the improvement...
... brain injuries to be expected in various types of facial trauma andto help in improved and better diagnosis of unsuspected xi brain injury, thereby resulting in decreasing the morbidity and ... costs Therefore, there is a need for biomechanical studies of head injury, its mechanisms andits tolerance to external loading To assess the biomechanics of head injury mechanisms, many finite ... of the helmet-strap-netting-FEHM assembly on the top while the preformed strap-netting system on the bottom; (B) The helmet, the strap-netting system andthe OA foam padding system before the...
... leading to increased transcription of inflammatory genes Activated GRs can then translocate tothe nucleus and interfere the binding between NF kappa B andits coactivators, resulting inthe inhibition ... swelling that arises from the middle meatus and ethmoid sinus and prolepses into the nasal cavityIn some cases, polyps also arise from the maxillary sinuses and from the middle and superior turbinates ... contact, preventing or slowing drainage, predisposing the patient to infection and leading to inflammation and edema [Messerklinger, 1978] From the ultrastructure view: (i) the nasal lining consists...