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Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf

Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf

Báo cáo khoa học

... purified catalytic subunit, 25 mM Tris/HCl (pH 7.4), mM magnesium acetate, mM dithiothreitol, 20 lM Kemptide and 0.1 mM [c32P]ATP (200 cpmÆpmol)1) [13] Reactions were incubated for 20 at 30 °C and ... essentially as described by Thomas et al [13] except that the reactions contain 20 lm, 10 lm, lm, 2.5 lm Kemptide The Ki value determined from the repots was 0.173 nm absorption peaks at 1683, 1669, 1653, ... K.L., Van Patten, S.M., Glass, D.B & Garetto, L.P (1990) Peptides and Protein Phosphorylation (Kemp, B.E., ed.), pp 43–84 CRC Press, Inc, Boca Raton Wen, W., Harootunian, A.T., Adams, S.R., Feramisco,...
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báo cáo khoa học:

báo cáo khoa học: "ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside" doc

Báo cáo khoa học

... duplication of the flt3 gene found in acute myeloid leukemia Leukemia 1996, 10:1911-8 Gilliland DG, Griffin JD: The roles of FLT3 in hematopoiesis and leukemia Blood 2002, 100:1532-42 Stirewalt DL, Radich ... 3:650-65 Levis M, Small D: FLT3: IT Does matter in leukemia Leukemia 2003, 17:1738-52 Sternberg DW, Licht JD: Therapeutic intervention in leukemias that express the activated fms-like tyrosine ... WD, Quentmeier H, Drexler HG: Effects of FLT3 ligand on human leukemia cells I Proliferative response of myeloid leukemia cells Leukemia 1996, 10:261-70 Zheng R, Levis M, Piloto O, Brown P, Baldwin...
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Báo cáo y học:

Báo cáo y học: "Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice" pot

Báo cáo khoa học

... http://arthritis-research.com/content/12/3/R92 23 Munugalavadla V, Vemula S, Sims E, Krishnan S, Chen S, Yan J, Li H, Niziolek P, Takemoto C, Robling A, Yang F, Kapur R: The p85alpha subunit of class IA phosphatidylinositol 3-kinase...
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Báo cáo sinh học:

Báo cáo sinh học: "Characteristics of predictor sets found using differential prioritization" docx

Báo cáo khoa học

... normal samples The MLL dataset [22] contains subtypes of leukemia: ALL, MLL, and AML The AML/ALL dataset [23] also contains subtypes of leukemia: AML, B-cell, and T-cell ALL Except for the BRN and ... PDL dataset [19] consists of classes, each class representing a diagnostic group of childhood leukemia The SRBC dataset [20] consists of subtypes of small, round, blue cell tumors (SRBCTs) In the ... JR: Classification, subtype discovery, and prediction of outcome in pediatric lymphoblastic leukemia by gene expression profiling Cancer Cell 2002, 1(2):133-143 Khan J, Wei JS, Ringner M, Saal...
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Báo cáo y học:

Báo cáo y học: "The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells" ppsx

Báo cáo khoa học

... possessing a higher expression of surface FcgRs (> 10 fold) compared with monocytes or monocytic leukemic cell lines rather than levels of Btk protein expression which are comparable (data not shown)...
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