signaling molecules ros and hormones
Environmental Adaptations and Stress Tolerance of Plants in the Era of Climate Change pptx
... Parvaiz Ahmad, and Nicole Geissler Prospects of Halophytes in Understanding and Managing Abiotic Stress Tolerance Vinayak H Lokhande and Penna Suprasanna UV-B Radiation, Its Effects and Defense ... photosynthesis, hormones and antioxidant system J Plant Physiol 164:709–717 Prospects of Halophytes in Understanding and Managing Abiotic Stress Tolerance Vinayak H Lokhande and Penna Suprasanna ... production of ROS ROS are very toxic for the organism as they affect the structure and function of the biomolecules The main source of ROS production in plants is chloroplasts, mitochondria, and peroxisomes...
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Báo cáo khoa học: Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway potx
... downstream signaling molecules was positively correlated with the intensity of tyrosine phosphorylation in InR and IRS-1, and tyrosine phosphorylation was proportional to the SLex content of InR-a and ... p42 ⁄ 44 MAPK and MEK were analyzed as the signaling molecules involved in InR signaling [19,23] Expression of b catenin and its downstream transcription factor TCF in the Wnt signaling pathway ... °C, 61.5 °C and 72 °C, for each) of PCR, and incubated at 72 °C for 10 and °C for Then 10 lL products were applied to agarose gel electrophoresis The amplified DNA bands were scanned and analyzed...
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Báo cáo hóa học: " Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)" potx
... intracellular IFNα, IFNβ and SOCS1 and SOCS3 protein levels were determined at 24 h and 48 h pi by flow cytometry (Figure 2) At 24 h or 48 h pi, IFNα and IFNβ protein expression in RSV and RSV mutant virus ... been shown to activate TLRs and retinoic acid inducible gene I (RIG-I) signaling pathways leading to phosphorylation of interferon regulatory factor3 (IRF3) and IRF7 and stimulation of type I interferon ... negative feedback loop that is time-dependent [24], thus RSV and RSV mutant virus infection of MLE-15 cells and IFNα, IFNβ and SOCS1 and SOCS3 mRNA expression was examined at 48 h pi At 48 h pi,...
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Báo cáo sinh học: "Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance" ppt
... at multiple levels, both extracellularly and intracellularly: the production and release of the ligands is regulated, and normally IGFs are also bound and transported by IGFBPs in extracellular ... homologous to vertebrate insulin and IGF-I have been identified as putative ligands of the Drosophila insulin receptor (dInR) [17] These Dilps are expressed in a spatially and temporally controlled ... to analyze the composition and bioactivities of Dilp2/Imp-L2/ALS complexes in Drosophila IIS coordinates nutritional status with growth and metabolism in developing Drosophila It has been shown...
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Báo cáo khoa học: "The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer" doc
... related cachexia and changes in the concentrations of APRPs, cytokines and hormones More studies should be performed to confirm this association between cachexia and APRP, cytokines, and hormones in ... loss and adiponectin levels (p < 0.01, r = 0.74) Also, we found positive correlation between midkine and albumin; similarly between both BMI loss and plasma leptin levels; and BMI loss and midkine ... anorexia nervosa and severe congestive heart failure [25] Elevated levels were recently reported in lung cancerinduced cachexia [26], and in a cohort of male patients with mainly lung and prostate cancer...
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báo cáo khoa học: " Cellular localization of ROS and NO in olive reproductive tissues during flower development" doc
... identical distribution of the labelling by TMB and DCFH2-DA), and the relative low presence of other ROS and NO in these stages (as showed by the DHE and DAF-2 DA fluorophores) (Figure 9) The average ... Confocal Laser Scanning Microscopy detection of ROS The DCFH2-DA (2’,7’-dichlorodihydrofluorescein diacetate) fluorochrome was used to detect ROS by Confocal Laser Scanning Microscopy (CLSM) Low magnification ... flower A and B: projections of section stacks of the stigma surface at stages and 3, respectively The fluorescence localizes in association with the stigmatic papillae C and D: optical section -and...
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Protein turnover in tissues effects of food and hormones
... image features Non-negative matrix factorizations Các bước băm ảnh số Feature Extraction Randomization Quantization Encoding 10 Các bước băm ảnh số Feature Extraction Lấy nét đặc ... cho băm ảnh số Đây bước có nhiều báo, nghiên cứu đề xuất phương pháp để lấy nét đặc trừng ảnh Randomization Trong bước liệu vector lấy từ bước Freature Extraction tạo băm việc sử dụng khóa...
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Contributions of Various Noncovalent Bonds to the Interaction between an Amide and S-Containing Molecules
... and angles in degrees 3536 www.chemphyschem.org 2012 Wiley-VCH Verlag GmbH & Co KGaA, Weinheim ChemPhysChem 2012, 13, 3535 3541 Interaction between an Amide and S-Containing Molecules b and ... of this entire problem, the global minithe literature is understandable as it occurs only in tandem mum of the complex between NMA and CH3SH is a product of with other, stronger noncovalent bonds, ... mol1, even though the H and S atoms are separated Each of the three S-containing molecules was paired with by 3.02 The last component with an E(2) above the 0.5 kcal NMA, and the potential energy...
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WCDMA UTRAN Interface and Signaling Procedure ISSUE 1.1
... this course, you will be able to: Understand UTRAN interface and structure Understand the definitions about UTRAN network elements Understand UTRAN signaling procedure Copyright © 2008 Huawei ... UTRAN Signaling Procedure Copyright © 2008 Huawei Technologies Co., Ltd All rights reserved Page18 SRNC/DRNC CN Iu SRNC Iur DRNC SRNC and DRNC are on a per connection basis between a UE and the ... reduce the resource occupancy and signaling transmission Copyright © 2008 Huawei Technologies Co., Ltd All rights reserved Page29 UE States - Reduce action ， DTX ， and save power RRC connection...
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Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... the (A) MAPK signaling pathway, (B) Notch signaling pathway, (C) EcR signaling pathway, (D) Hippo signaling pathway, (E) TGF-b signaling pathway, (F) Hh signaling pathway, and (G) Wnt signaling ... vertebrates The Drosophila miRNA bantam is a direct transcriptional target of the Hippo signaling pathway, and it has been shown to promote growth and inhibit apoptosis [28,29] The Drosophila miR-278 ... bound to the Drosha–DiGeorge syndrome critical region gene miRNAs and cell signaling complex and RNA helicase p68 The recruitment of the R-smads stimulates the production of these miRNAs and thus...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx
... Although, steroid hormones are critical players in sexual differentiation and both HOXC13 and steroid hormones are linked with hair follicle growth and difference in hair patterning in males and females, ... DNA-binding domain, a ligand-binding domain and a transactivation domain The DNA-binding domain is responsible for DNA binding specificity and dimerization, and the ligand-binding domain is responsible ... and E2F6, MLL2 interacts with E2F2, E2F3, E2F5 and E2F6 [34] Similar to E2Fs, the G1-phase regulator HCF-1 recruits MLL1 and Set1 to E2F-responsive promoters and induces histone methylation and...
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Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf
... protein tyrosine phosphatase (PTP) superfamily, PTP1B, acts as a positive mediator of the ErbB2-induced signaling pathways that trigger mammary tumorigenesis and metastasis [12,13], and the tyrosine ... ⁄ Thr and Tyr residues [18] Several DSPs have been established as MAPK phosphatases that dephosphorylate the Tyr and Thr residues in the activation loop of MAPKs and thereby attenuate signaling ... with endosomal and Golgi structures using specific markers (EEA1, TfnR for endosomes and GM130, TGN46 for Golgi) and found that JSP1-wt partially colocalized with the Golgi apparatus and showed minimal...
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Tài liệu Báo cáo khoa học: a-Defensins increase lung fibroblast proliferation and collagen synthesis via the b-catenin signaling pathway doc
... kinase and PI3K ⁄ Akt and increase phosphorylation of GSK3b on Thr390 and Ser9 SB203580 and LY294002 prevented a-defensin-induced increases in the protein contents of Thr390-phosphorylated and Ser9-phosphorylated ... a-defensin-1 and a-defensin-2 induced increases in the phosphorylation of GSK3b and b-catenin activation and that inhibition of b-catenin activation prevented a-defensin-induced proliferation and collagen ... a-defensin-1 and a-defensin-2 increases collagen synthesis, HFL-1 lung fibroblasts were incubated with a-defensin-1 and a-defensin-2 (0.5–6 lm) for 24 h and then collagen protein content and the collagen-I...
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Tài liệu Báo cáo khoa học: DNA methylation-mediated nucleosome dynamics and oncogenic Ras signaling pptx
... genetics and epigenetics in Ras oncogenic signaling There is a bilateral relationship between genetic and epigenetic mechanisms in the activation of oncogenic Ras signaling Activation of K-Ras and ... H-Ras and K-Ras signaling that is facilitated by lipid rafts, on the one hand [98,144] (Fig 3A), and radiation ⁄ chemotherapy can cause demethylation-induced FAS expression, on the other hand (Fig ... serine 10 and 28 phosphorylation in an acetylation-dependent and -independent fashion [55] In summary, activation of the Ras -signaling pathway would trigger the methylation aberrations and histone...
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Tài liệu Báo cáo khoa học: Osmotic stress sensing and signaling in fishes doc
... sense and quantify changes in environmental salinity and to activate appropriate compensatory responses Thus, euryhaline fishes represent excellent models to identify and understand elements and ... is sufficient for moving ions across membranes at a rate that offsets water movement across membranes This is only possible for small and slow osmolality changes and it depends on cell type-specific ... stress sensing and signaling in fishes D F Fiol and D Kultz ¨ composition of the cell membrane, including the abundance of particular ion channels, ion transport proteins, aquaporins and membrane...
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Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... phosphorylation and ROS [15] The findings localize endosomal acidification most upstream in the signaling cascade underlying hyperosmotic ROS production Osmosignaling in proliferation and apoptosis ... interrelation between osmotic shrinkage and ROS production has been established On the one hand, hyperosmotic shrinkage induces ROS production (see above) and, on the other, ROS mediate cell shrinkage Thus, ... shrinkage and ROS production are connected in an autoamplificatory signaling loop Mutual amplification of shrinkage and ROS triggers apoptosis, which could be prevented by NAPDH oxidase inhibitors and...
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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf
... Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets Blood 104, 1745–1752 26 Cavallini L, Coassin M, Borean A & Alexandre A (1996) Prostacyclin and ... Farndale RW & Sage SO (1993) ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate ... P2Y12 signaling is conserved in mouse and human platelets, but also highlight the importance of the PI3-Kb isoform PI3-Kb and not PI3-Kc mediates P2Y12-dependent procoagulant activity of mouse and...
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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... both aA- and aB-crystallin possess at least two binding modes, and that these are influenced by both external factors (e.g changes in temperature and pH) and intrinsic factors (e.g mutation and phosphorylation) ... formed by the ordered aggregation of RCMj-CN and a-synucleinA53T Electron micrographs of RCMj-CN (0.5 mgÆmL)1, A and B) and a-synculeinA53T (2.0 mgÆmL)1, C and D) 500 lgÆmL)1) following incubation ... formation of fibrils, which were long (between and nm), straight and unbranched (Fig 6C,D) Addition of Gly and Lys-HCl at 250 mm increased both the rate and magnitude of the change in ThT fluorescence...
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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx
... Inc (Rockford, IL, USA) WGA–Sepharose 6MB (WGA– Sepharose), protein G–Sepharose, protein A–Sepharose and other chemicals were purchased from Sigma-Aldrich Animals and injections Animal studies were ... the light mitochondrial–microsomal and cytosolic fractions than in the nuclear and mitochondrial fractions (P < 0.001) Analysis of separate light mitochondrial and microsomal fractions showed that ... internalization and phosphorylation of the IR [17–19], IR content decreased in the plasma membrane fraction and reciprocally increased in the light mitochondrial–microsomal and Golgi ⁄ endosome fractions, and...
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Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf
... disorders, cancer, fibrosis and autoimmune disorders Signaling is initiated by binding of the cytokine to a homodimeric complex of cytokine receptor type II, which recruits type I receptor and activates ... with cell type and signal-specific transcription activators or repressors There are three classes of Smads: regulatory Smads (BMP-responsive R-Smads 1, and and TGFb-responsive R-Smads and 3), the ... and 3), the coSmad Smad4 and the inhibitory Smads and All R-Smads and the co-Smad consist of three domains: the N-terminal MH1 domain, the variable proline-rich linker, and the C-terminal Mad homology...
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