... Poly( ester urethane)urea PGA : Poly( glycolic acid) PLGA : Poly( lactic- co-glycolic acid) PLLA : Poly( L- lactic acid) PMMA : Poly( methylmethacrylate) pNIPAM : Poly( N-isopropylacrylamide) PVA : Poly( vinyl ... on the PLLA/Col, the PLLA/Col+MSC and the Col membrane implants 168 Figure 5.9 The volume of bone matrix produced by the PLLA/Col/HA, the PLLA/Col/HA+MSC and the Col membrane/BMP-2 implants ... mineralization of PLLA (PLLA/HA); (C) nanofibrous PLLA/Col (80:20); (D) mineralization of PLLA/Col (PLLA/Col/HA); and their 154 Figure 5.2 Changes in the number of viable cells during culture in...
... blocks the loss of PGs from the cartilage matrix into the synovial space, maintaining the normal cartilage matrix [3] Similarly, HA may also help prevent invasion of inflammatory cells into the ... calcification or extracellular matrix degradation [43] Role of hyaluronan in the synovial fluid HA is responsible forthe viscoelastic quality of synovial fluid that acts as both a lubricant and shock ... Moreland Cartilage effects of hyaluronan and hylans The effects of HA and hylans on cartilage histology are well documented in experimental animal studies, but strong clinical trial data is lacking...
... and capsular tissue Limitations ofthe current study include a lack of comparison group and lack of blinding A randomized, controlled clinical trial would be ideal to further verify the efficacy ... have limited follow-up Because ofthe capacity for peripheral nerves to regenerate, long term outcome following ablation ofthe dorsal nerve root or its branches should be evaluated Cho et al reported ... following dorsal root rhizotomy We speculate that the direct visualization ofthe joint allows better de-innervation ofthe joint and removal ofthe entire end-plate receptors that adhere to the...
... central or foraminal stenosis treated with endoscopic laminoforaminoplasty via a small incision, of less than one inch Materials and Methods Twelve patients were treated with endoscopic laminoforaminoplasty ... endoscopic laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the ... cervical laminoforaminotomy for unilateral radiculopathy: results of a new technique in 100 cases J Neurosurg 2001; 95: 51-57 Khoo LT, Fessler RG Microendoscopic decompressive laminotomy forthe treatment...
... general, the higher concentration of primers can lead to the formation of primer dimers Also, the cost ofthe chemicals should be minimized if the same quantitativeness can be achieved The results ... took the role of full nitrification in Run REFERENCES Amann, R.I., Ludwig, W and Schleifer, K H 1995 Phylogenetic identification and in situ detection of individual microbial cells without cultivation, ... MLVSS, DO, ORP, water temperature Microbial analyses Activated sludge samples were added with ethanol at a final concentration of 10%, then transported to the laboratory of UT at 4oCstored Then,...
... HRT led to a slight increase in the PO43 P removal These results revealed that the selection ofthe operational parameters ofthe CARS process had a great influence on the overall system performance ... experimental results well The obtained values ofthe constant characteristics forthe two models are listed in Table CONCLUSIONS In this study, technical feasibility of this process was demonstrated The ... were L, 12 L and 10 L, respectively The adsorption tank had an inflow of 10 L/ h Domestic wastewater was collected with a central sewerage network forthe preparation ofthe influent wastewater The...
... Royal College of Physicians’ Medical Oncology Joint Special Committee Royal College of Radiologists Royal College of Surgeons NICE technology appraisal guidance 118 32 Royal Pharmaceutical Society ... Mental Health Consultant, National Institute for Mental Health in England Professor Jonathan Michaels Professor of Vascular Surgery, University of Sheffield Dr Neil Milner General Medical Practitioner, ... Economist, London School of Hygiene Dr Fergus Gleeson Consultant Radiologist, The Churchill Hospital, Oxford Ms Sally Gooch Former Director of Nursing & Workplace Development, Mid Essex Hospital Services...
... the result of an exchange ofthe amino acid valine for glutamine in the β-globin chain ofthe hemoglobin molecule This abnormal hemoglobin becomes polymerized, causing the red blood cell to assume ... effectively lower the concentration of Hb S within a cell, resulting in less polymerization ofthe abnormal hemoglobin Hydroxyurea’s efficacy in sickle cell disease is generally attributed to its ability ... sickle shape and making the cell both rigid and fragile These distorted cells obstruct the blood vessels and may disrupt endothelial cell function, leading to tissue hypoxia and clinical complications...
... in the cell culture medium Metal-CQ treatment decreased the levels of extracellular Ab not by preventing an Ab–metal interaction outside the cell, but by facilitating the delivery of metals into ... substantially decreased the levels FEBS Journal 274 (2007) 3775–3783 ª 2007 The Authors Journal compilation ª 2007 FEBS 3777 Modulation of metal availability for treating AD P J Crouch et al of soluble ... makes them potentially toxic to the cell Under conditions where they are allowed to accumulate freely, redox active metals contribute directly to cellular oxidative damage by generating the highly...
... completed; superseded by moxetumomab pasudotox Clinical trials Clinical trials Clinical trials Clinical trials T and B cell malignancies Mesothelioma, lung cancer Brain tumors Clinical trials ... although the order of events in vivo has not been established experimentally The subcellular location ofthe reduction event is difficult to pinpoint The general redox state ofthe extracellular ... molecule of PE in the cytosol may be sufficient to kill a cell Typically, cells in culture require treatment with concentrations of PE greater than 1000 molecules per cell (approximately 10)16 gÆcell)1)...
... adjunctive therapy or the actual exercise dosage is the critical factor is unclear The optimal length oftreatment and the number oftreatment episodes could be useful information forthe marketing of ... the quality of life Yonsei Medical Journal 2000, 41(2):237-251 Bo K, Talseth T, Holme I: Single blind, randomised controlled trial of pelvic floor exercises, electrical stimulation, vaginal cones ... additional file 5] is provided The methodological quality ofthe RCTs varied from 23/23 (100%) [34] to 9/23 (39%) [36] The methodological quality ofthe level III and IV studies was also variable with...
... causes water to leave the cell, followed by cell shrinkage and damage to the intracellular matrix (especially protein) due to high-salt content (NOTE: The extracellular osmolality ofthe prostatic ... similar to the tip ofthe cryoneedles, especially in the transverse view Placing the needles in the sagittal plane can overcome this difficulty, since the length ofthe cryoneedles can be easily ... understanding ofthe principles and strategies forthe cryosurgical treatmentof localized prostate cancer The report is based on review of available professional literature, as well as clinical experience...
... wall quenching effects ofthe colder cylinder walls The NOx is formed during the very high temperatures (>1500 ◦C) ofthe combustion process resulting in thermal fixation ofthe nitrogen in the ... a collection of smaller carbonaceous spherules The terms agglomerate (100 mm typical size), particle (0.1–1 mm) and spherule (10–50 nm) will be used for these three scales of particulate The ... attached at the position ofthe catalyst bed inside an electric furnace The temperature ofthe catalytic bed was directly controlled by the proportional_integral_derivative (PID) controller ofthe furnace...
... of VLC, ascites associated cells were concentrated by centrifugation and then red blood cells were lysed using ACK buffer (lonza, Walkersville, MD Host cells were then isolated using a Ficoll ... cells were lysed using ACK buffer, and whole ascites cell samples were analyzed for VLC by FACS Treatmentof Flank Tumors 20 × 106 ID8-VEGF cells were injected subcutaneously into the flanks of ... Alemtuzumab killing is complementmediated rather that cell-mediated, Alemtuzumab killing is less likely to be negatively impacted by dysfunctional cellular immunity This is consistent with the...
... significantly less acidotic than the intracellular lysosomal compartments of cells[124,126] Furthermore, there would be rapid doxorubicin release following particle endocytosis into tumor cell lysosomal ... in the Microvessel Endothelial Glycocalyx: A Possible Explanation for Molecular Filtering? Journal of Structural Biology 2001, 136:239-255 Curry FE, Michel CC: A fiber matrix model of capillary ... positively charged small molecules are attached to the exterior of nanoparticles with long blood half-lives, the prolonged exposure ofthe cationic particle surface to the glycocalyx can result in...
... perturbations Clinical testing included the evaluation ofthe following clinical scales: EDSS and Functional Systems Score [31], Scripps’ NRS [32], Ashworth scale [38], the Ataxia Vergaro et al Journal of ... position ofthe hand was also continuously displayed, as a yellow circle (diameter 0.5 cm) The nominal amplitude ofthe movements (distance ofthe targets from the center position) was 10 cm The sequence ... separately forthe two arms The same neurologist examined all the subjects Detailed demographic information is reported in Table The research conforms to the ethical standards laid down in the 1964...
... fixation for isolated olecranon fractures leads to good elbow function and minimal loss of physical capacity The technique remains the "gold standard" forthetreatmentof displaced and minimally comminuted ... detected Finally, all the patients were recalled to attend a specially set up clinic forthe final assessment with respect to the purpose ofthe study Ethics Committee approval was obtained Flexion-extension ... direct injury to the posterior part ofthe elbow joint or indirectly by forces generated within the triceps muscle during a fall on a partially flexed elbow [15] The clinical picture is obvious...
... and contralateral VFG was applied in cases, in which one was forthe initial trial of VFG, and the other was forthe second trial of VFG after failure of bone consolidation in ipsilateral VFG Patients ... old, and casting healed the fracture Conclusion In conclusion, the overall long-term follow-up results of VFG were excellent However, residual limb-length discrepancy and ankle pain were prominent ... reported in half the patients with intramedullary nails [7] Such surgical procedures with a potential danger of damaging the growth plate may result in limb-length discrepancy Therefore, the deformity...
... spinal instability results, and the spinal segment will eventually fail with weight-bearing Biomechanical studies have also shown that spinal instability results when there is a failure of at least ... 37 42 L1 T11 T12 L1 T12 T12 T12 T11 T12 T12 L1 L1 T12 L1 T12 L1 T12 T11 T12 T11 L1 T12 T12 L1 L1 T11 T11 T11 L1 L1 T12 MVA MVA MVA MVA MVA MVA MVA MVA MVA Fall Fall MVA Fall MVA MVA Fall MVA ... level arm ofthe construct would probably not only enhance the stability but also allow effective reduction of kyphotic deformity SSPF alone can give good clinical and radiological outcomes for...
... on leg length and the ability ofthe femur to deformity remodeling at this level Thetreatmentof displaced supracondylar fractures ofthe femur depends on the age and size ofthe child, the ... size was too large forthe child’s femur Forthe LISS tibial plate, the size was quite a good fit and was well-contoured over the distal femoral condyle and the multiple distal locking screws ... by the Editor-in-Chief of this journal Conclusion In the literature, there is no report ofthe use of LISS tibial plates forthetreatmentof paediatric supracondylar fractures ofthe femur They...