anti inflammatory agents for the treatment of ra
Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf
... before and after the clinical improvement This leaves us to the discussion of the anti- inflammatory effects of antipsychotic medication on CRP levels and a patient’s clinical symptoms The literature ... Baune and Eyre: Anti- inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report Journal of Medical Case ... informed consent was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of...
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Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"
... Conclusions Thoracic radiculopathy is rare, as evidenced by the paucity of literature regarding the appropriate management of these patients In our experience, patients with thoracic central and foraminal ... group Conflict of Interest The authors have declared that no conflict of interest exists References Kunogi J, Hasue M Diagnosis and operative treatment of intraforaminal and extraforaminal nerve ... tend to be of older age than patients with cervical or lumbar disease Also, the stenosis tends to be foraminal and not central since 66% of patients had foraminal stenosis The lower thoracic spine...
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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf
... collected at the University of Pennsylvania or the University of Michigan After obtaining informed patient consent, ascites was collected either intraoperatively or at the time of therapeutic paracentesis ... density [15,19] However, these antibodies were against murine antigens, and therefore not directly translatable to humans The therapeutic effect seen with anti- CD52 therapy of ovarian tumors in mice ... immunotherapeutic target antigen In fact, an anti- human CD52 antibody therapy, Alemtuzumab (Campath) has been developed and is FDA approved for the treatment of CD52 expressing leukemia Taken together,...
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Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx
... returned in 32 out of the 40 patients (80%) The median age at the time of radiotherapy was 44 years (range 17-83 years) The tumor manifestation was on the right eye in 16 patients and on the left eye ... symptoms Several groups have reported their clinical results of precision radiotherapy for the treatment of ONSM Figure Correlation of PTV-size and visual outcome Patients with smaller treatment ... mask allows an overall positioning accuracy of 1-2 mm With the mask fixed to the stereotactic base frame, contrast-enhanced CT and MRI scans were performed for treatment planning For patients without...
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Báo cáo khoa học: " Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans" ppsx
... M, Pierart M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a Page 10 of 11 (page number not for citation ... V20 of 59% and V10 of 73% It is possible that sparing of the femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of our study reinforce the ... combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup...
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Báo cáo y học: " Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Canada" ppt
... manuscript KC was the information specialist for the manuscript NA assisted with the overall design of the study and preparation of the manuscript JET assisted with the preparation of the manuscript ... and the uncertainty of a therapeutic advantage over alternative therapy The objective of this study is to evaluate the cost-utility of IVIG compared to corticosteroids for the treatment of CIDP ... expertise in the development of the economic model and helped write the manuscript RG assisted with the overall design of the study and preparation of the manuscript All authors read and approved the...
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Báo cáo y học: "The effectiveness of ENAR® for the treatment of chronic neck pain in Australian adults: a preliminary single-blind, randomised controlled trial" potx
... they may not feel the electrotherapy during the trial, thereby minimising any perception of a treatment either occurring or not Each of the groups received 10 minutes of their respective therapy, ... to the ENAR therapy group except that the unit was turned on and then immediately off before being applied to the skin Prior to commencement of the study all participants were advised of the ... reported in the literature this study formed a foundation for knowledge relating to the use of this type of therapy A methodology was developed which allowed the assessment of both the short and...
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Báo cáo y học: " A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults" pdf
... proportional for the 200 mg and 400 mg dose levels of IV Ibuprofen, see Table Figure demonstrates the mean plasma concentrations of ibuprofen for each of the three drug dosage arms in both the critically ... using the linear-log trapezoidal rule: linear trapezoidal rule up to time to maximum concentration, and then a log trapezoidal rule for the remainder of the curve, where the last measurable time ... before dosing and for all temperature measurements during the treatment period Treatment consisted of one dose of study drug every four hours, for a total of six doses Assessments of temperature,...
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design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas
... analogues 115 4.15 Methology suitable for the radiosynthesis of the E isomer of CA-1 121 4.16 Radiosynthesis of the E isomer of CA-1 123 4.17 Scale-up synthesis of OXi8007 124 4.18 Proposed nitrogen ... antineoplastic agents is based on their mode of action and the phase of the cell cycle in which the drug acts If the action of the drug is most effective at any particular phase of the cell cycle, the drug ... Although chemotherapy is used as a primary treatment or as an adjuvant to the other therapies, it often has unpleasant side effects because of the limited selectivity that these drugs have for cancer...
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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique
... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... improvement from the radiofrequency procedure, the length of improvement varied from months to 16 months Again, no one in the radiofrequency group developed permanent relief of their pain Thus, the endoscopic...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... evaluate the inhibitory effect of some thioglycosides synthesized in our laboratory on human hSGLT1 and hSGLT2 –as a potential therapeutic alternative for the control of hyperglycemia, particularly for ... 21-26] Among these, thioglycosides are important to consider because they are not hydrolysed by β-glucosidases in the intestine and can be administered orally [27] Therefore, the aim of the present...
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Behavior of Nitrite Oxidizers in the Nitrification/Denitrification Process for the Treatment of Simulated Coke-Oven Wastewater
... In general, the higher concentration of primers can lead to the formation of primer dimers Also, the cost of the chemicals should be minimized if the same quantitativeness can be achieved The results ... water temperature Microbial analyses Activated sludge samples were added with ethanol at a final concentration of 10%, then transported to the laboratory of UT at 4oCstored Then, each of the samples ... two One of them was for DNA extraction and was washed with TE buffer at pH8.0, and stored at -20oC Another was for FISH analysis and was stored at -80oC The extraction of DNA was performed with...
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Contact-Adsorption-Regeneration-Stabilization Process for the Treatment of Municipal Wastewater
... with the increased HRT of the adsorption tank From an engineering application point of view, the appropriate operational parameters of the recycle ratio, HRT of the regeneration tank, HRT of the ... of the regeneration tank Fig illustrates the effect of HRT of the regeneration tank on the CARS system performance The COD removal increased with an increase in HRT of the regeneration tank from ... different HRTs of the regeneration tank Effect of recycle ratio (R) The recycle ratio of the CARS process played an important role in the substrate removal They had a significant influence on the output...
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Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx
... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival of the patients in the cetuximab monotherapy arm of the RCT The data from the monotherapy arm NICE ... with a grade rash, 6.2 months for NICE technology appraisal guidance 118 12 those with a grade rash and 4.3 months for those with no rash (p = 0.0008, grade vs grade 1−3) 4.1.13 In the RCT the incidence ... fitness, rather than age, is the primary factor when considering whether chemotherapy is appropriate The Committee therefore agreed that the patients included in the NICE technology appraisal guidance...
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Hydroxyurea for the Treatment of Sickle Cell Disease docx
... reviewers; for the other study designs, the results of the two reviewers were averaged The overall score was the percentage of the maximum possible score, ranging from to 100 percent The results for RCTs ... 1967 for the treatment of neoplastic diseases 14 In subsequent years, clinical trials demonstrated the efficacy of this drug for the treatment of CML, psoriasis, and polycythemia vera Although there ... use of this drug for sickle cell disease Therefore, we sought information on barriers to the use of other therapies for treatment of sickle cell disease, including the receipt of routine, scheduled...
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Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx
... central to all of these AD-related neurodegenerative mechanisms, the modulation of metal bio-availability has strong potential in the therapeutic treatment of AD References Goedert M & Spillantini ... responsible for the deficit in energy metabolism characteristic of AD brain [21] There are conflicting reports in the literature about levels of the cuproprotein ceruloplasmin (Cp) in AD brain [22,23], ... Ab forms amyloid plaques As amyloid plaques are prominent in the postmortem AD brain, early research theories placed the accumulation of extracellular, insoluble forms of Ab as central to the...
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Báo cáo khoa học: A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer ppt
... the inclusion of lysine residues in the protein sequence of the A fragment but not the B fragment of PE Because only the A fragment must traffic to the cytosol for activity, the lack of lysine residues ... the presence of a misfolded protein in the ER to exploit the ERAD system for transport across the ER membrane to the cytosol [91,92] To date, we are unaware of direct evidence for transport of ... and the two fragments separate (7) The A fragment is subsequently transported into the cytosol (8), possibly by exploiting the ERAD pathway through the Sec61 translocon In the cytosol, PE transfers...
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Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc
... evidence for the optimal period of treatment and number of treatments? We found evidence for the efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis of the ... exercise dosage is the critical factor is unclear The optimal length of treatment and the number of treatment episodes could be useful information for the marketing of physical therapy for SUI Some ... can be drawn Physiotherapists were the only health professionals stated to be performing the treatment (in 83% studies), and while continence training can be assumed for the therapists in these...
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Best Practice Policy Statement on Cryosurgery for the Treatment of Localized Prostate Cancer pptx
... Board of Directors of the AUA Funding of the Panel and of the PGC was provided by the AUA, although Panel members received no remuneration for their work Each member of the PGC and of the Panel ... of slow freezing by losing water to the extracellular milieux, thereby reducing the probability of intracellular ice formation Temperature Monitoring – The Panel strongly advises the use of thermocouples ... persisting for one or two weeks postoperatively is treated with either a suprapubic or Foley catheter After the freeze, the gland swells for a variable time, and the use of anti- inflammatory agents...
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SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE
... choice and loading of the NM is a compromise between the required efficiency of the converter and the market price of the NM However, the application of noble metals for the treatment of exhaust gas ... full integration of the catalyst into the emission control system The catalyst has become integral in the design strategy for vehicle operation [43] 1.3 Catalyts for the exhaust gas treatment ... continuous regeneration of the trap A major drawback of these systems is related to the capability of Pt catalysts to promote SO2 oxidation as well The sulphate thus formed is then deposited on the particulate...
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