... Similarly, the e-amino group of K387 couldform a salt bridge with the close carboxyl group of E395 andfurther stabilize the peptide structure within the complexwith the antibody.In the virus, the ... In some ofthe conformers a hydrogen bondwas predicted between the carbonyl atom ofthe Cys386residue and the main chain nitrogen atom of residue Ile390. The total contact surface ofthe epitope ... exception) the reactivity of all peptides exhibiting the binding motif.More than 90% ofthe MV-HNE sequences found in the databases were recognized by the neutralizing antibodies. In the absence of...
... hold the b-sandwich in position. With the exception offour a-helices and t wo pairs of short b-strands, the rest ofthe protein consists almost entirely of loopsconnecting the b-strands. The ... is the predominant product of hydrolysis and increases inconcentration as the reaction proceeds [21]. The exo-loop of 1CEL (amino acids 243–256) forms the roof ofthe active sitetunnel at the ... confirmed the identity ofthe T. emersonii cel7 gene/gene product; the location of these peptides in the deduced polypeptidesequence is given in the legend to F ig. 1. Comparison of the d educed...
... amino acids. The amino acid sequence of the L. australasiae ecdysone receptor was similar to that ofthe ecdysonereceptor-A ofthe soft tick, Ornithodoros moubata (68%) and to that of the ecdysone ... regions. The C-regions of EcRs andUSPs are highly conserved. However, other regions,particularly the N-terminal parts of USP ⁄ RXR, vary. The alignments of amino acid sequences ofthe A ⁄ B ... with the phylogenetic relationship. The E region of LaEcR-A is most similar to that of OmEcR (86%). Although the E region of LaEcR-A isvery similar to those of insect EcR-As, the similarityof...
... amount of gas ?kTktr23Now we consider an ideal gas in aspects of energy3.1 Internal energy ofideal gas: The kinetic- molecular model states that The internal energy of an ideal gas is ofthe ... average"One ofthe keys ofthe kinetic- molecular model is to relate pressureto collisions of molecules with any wall: 4/22/2008 4Đ1. Kineticmolecular model of an ideal gas:1.1 Equations of state of ... capacity ofideal gases: We have had before the result:Molecules in their motion have a kinetic energy Themolecularkinetic energy is proportional to the absolute temperatureWhat is the energy of...
... those ofthe parent protein, andinvestigated the exchange kinetics ofthe correspondingdimers. The P19A mutation slightly increases the thermalstability ofthe monomer, but it does not alter the ... evaluation ofthe effect of singlepoint mutations on the solution structure of monomericderivatives, we analysed the 2D NMR spectra of the different variants of mBS. Figure 3 shows the expandedregions ... our results provide furtherevidence ofthe evolutionary significance ofthe A19P andQ28L substitutions in the path leading from RNase A toFig. 6. Kinetic analysis ofthe MxM to M=M conversion...
... the locations ofthe sensors. The numerical simulation is applied to a base excited cantilever beam to illustrate the algorithm. The effects ofthe time delay and the location of sensor are ... Acknowledgements. The paper is based on the talk given at the Conference on Mathematics, Mechanics, and Informatics, Hanoi, 7/10/2006, on the occasion of 50th Anniversary of Department of Mathematics, ... shapes ofthe beam. To see more clearly, we plot the history ofthe error term. Since the measurement matrix C has 2 rows, the error term E(t) in (12) is a 2-dimensional vector. The histories of...
... term. The magnitude ofthe error term depends on the number and the locations ofthe sensors. The numerical simulation is applied to a base excited cantilever beam to illustrate the algorithm. The ... algorithm is the requirement ofthe knowledge of entire state vector x(t). 4. Combination ofthe identification algorithm and the modal superposition method The incomplete measurement leads to the incomplete ... Journal of Science, Mathematics - Physics 23 (2007) 131-138 136 Fig. 3. The 1st, 3rd and 5th mode shapes ofthe beam. To see more clearly, we plot the history ofthe error term. Since the measurement...
... have identified interaction(s) ofthe CIDD domain of ERM with the C-terminal domain of CHD3. The ABFig. 7. Effect of C-terminal deletions of CHD3 on the inhibition of transcription by CHD3 and ... sequence with the centralconsensus 5Â-GGAA T-3 (Fig. 1A) [18,20]. Based on the sequence homology ofthe ETS domain, and the conservation of other functional domains, a phylogenictree ofthe ETS ... activity,indicating the crucial importance of these two Etsmotifs [15]. In addition to controlling the level of geneexpression, Ets factors may direct the choice of the promoter elements in play, and therefore,...
... in the regulation of these genes. It should be noted that,although the exact positions ofthe AREs are not con-served between different mammalian species, at least50% of all AREs in all of these ... 6C).Therefore, knockdown ofthe PRDX5 gene stimulatedtranscription of some families of human satellite DNA,which may be caused by direct involvement of PRDX5in silencing ofthe transcription of ... bars)shows the results of analysis of 8-oxoG in the controland KD-1 cells. In the KD-1 cells, the concentration of endogenous 8-oxoG was significantly increased,indicating that PRDX5 contributed to the...
... submitfor the consideration of the Government of the UnitedStates the followingstatement of facts and of the at-titude of myGovernment and itspeopleconcerning the decision of the Alliedand ... therecanbepeace."II. The settlement of everyquestion,whether of territory, of sovereignty, of economicarrange-ment,or of political relationship, upon the basis of the freeacceptance of that settlementby the peopleimmediatelyconcerned,andnotupon the basis of ... seventies of the lastcentury, bywhichthey pledgedpermanent sup-portto the dynastyinitspolicies of suppression of the othernationalities of Austria-Hungaryand receivedfullcontrol of the provincial...
... studiesreliably.Another relevant issue regarding the findings ofthe AAQvalidation is the construct similarity between the interna-tional sample and the Brazilian one. The three factors pro-posed by the ... indicate that the per-ception of aging did not differ significantly between the two samples and raises the question of whether these sim-ilarities remain or not in other different cultures. The demonstration ... original form. Asmentioned above, the Chi-Square (both for the modeland for items separately) has the purpose of assessingwhether the data collected fits the expected theoreticalmodel. Thus, p values...
... osteoar-thritis of 1 grade in 52% ofthe patients, 35% of the patients had an increase of 2 grades and 3% ofthe patientshad an increase of 3 grades. (Table 4, 5 and 6) 10 % of the patients had ... per-formance, the score may appear too high, and will reflect the actual function ofthe knee as well as the satisfaction of the patient. The Lysholm score has never been validatedfor the purpose of following ... test). Thesepatients were considered at high risk of further knee injurydue to the degree of laxity and the desired level of activity[27]. In order to minimise the development of arthrofi-brosis,...
... psychometric theory and Rasch Analy-sis in the validation ofthe AAQ instrument in a Braziliansample of older adults.MethodsPilot study The pilot study followed the methodology applied by the WHOQOL ... studiesreliably.Another relevant issue regarding the findings ofthe AAQvalidation is the construct similarity between the interna-tional sample and the Brazilian one. The three factors pro-posed by the ... indicate that the per-ception of aging did not differ significantly between the two samples and raises the question of whether these sim-ilarities remain or not in other different cultures. The demonstration...