other reasons for heart failuresymptoms in patients with normalejection

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography

... shortens Ͼ 50 ms in patients with a marked elevation of ﬁlling pressures In cardiac patients, mitral E velocity increases with exertion and stays increased for a few minutes after the termination of ... function should be an integral part of a routine examination, particularly in patients presenting with dyspnea or heart failure About half of patients with new diagnoses of heart failure have normal ... Recommendations for Clinical Laboratories 127 A Estimation of LV Filling Pressures in Patients With Depressed EFs 127 B Estimation of LV Filling Pressures in Patients With Normal EFs 127 C Grading Diastolic...

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Báo cáo y học: "A neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report" pps

Danh mục: Báo cáo khoa học

... screening evaluation for a possible inherited thrombophilia disorder was completed in this baby Blood levels for protein C, protein S, antithrombin activity, concentrations of clottable fibrinogen, ... a lobar segment indicates that an intrauterine insult had occurred between weeks five and eight of gestation [13] We postulate that a vascular injury occurring within this timeline caused an LPA ... underlying etiology for such clinical presentation Consent Written informed consent was obtained from the parents of this patient for publication of this case report and any accompanying images...

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Báo cáo y học: " A neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report" pot

Danh mục: Báo cáo khoa học

... screening evaluation for a possible inherited thrombophilia disorder was completed in this baby Blood levels for protein C, protein S, antithrombin activity, concentrations of clottable fibrinogen, ... a lobar segment indicates that an intrauterine insult had occurred between weeks five and eight of gestation [13] We postulate that a vascular injury occurring within this timeline caused an LPA ... underlying etiology for such clinical presentation Consent Written informed consent was obtained from the parents of this patient for publication of this case report and any accompanying images...

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Báo cáo y học: "Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters" doc

Danh mục: Báo cáo khoa học

... the bicinchoninic acid (BCA) assay (Pierce, Rockford, IL, USA) The serine protease inhibitor aprotinin (Sigma) and the ACE inhibitor lisinopril (Sigma) were used to inhibit proteases other than ... Chengdu, China) in ventilated whole body exposure chambers (70 × 50 × 50 cm; with a small electric fan inside for chamber mixing) for 30 each time, twice per day for up to four months with minor modifications ... chymostatin administration significantly reduced the smokeinduced increase in chymase activity but had no effect on ACE activity, suggesting that chymostatin was mainly acting through the inhibition...

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Báo cáo y học: "Acute pressure overload of the right ventricle. Comparison of two models of right-left shunt. Pulmonary artery to left atrium and right atrium to left atrium: experimental study" doc

Danh mục: Báo cáo khoa học

... variable at baseline was 95.5 ± 10.45 pulses/min, at 10 minutes interval with PA - LA shunt was 112.80 ± 9.71 pulses/min and at 20 minutes interval 105.20 ± 16.90 pulses/min, whereas with the RA - ... transplantation in patients with severe rightheart failure refractory to conventional therapy [2-5] BAS aims at creating a “safety valve” by unloading the right heart and increasing left ventricular ... favor of PA-LA shunt insinuate easier manipulation of heart function in order to optimize heart performance by simple maneuvers like volume infusion or medical intervention in cases of real conditions...

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báo cáo khoa học: "Anomalous origin of the left coronary artery from the pulmonary artery associated with an accessory atrioventricular pathway and managed successfully with surgical and interventional electrophysiological treatment: a case report" docx

Danh mục: Báo cáo khoa học

... pharmacological therapy and in patients with life-threatening arrhythmias The main reasons for this approach are the natural history of SVT with resolution of episodes in infancy [3-6], the risk ... doses without success An electrophysiological study was performed in the fourth post-operative week using a 5-French decapolar catheter placed into the left subclavian vein in the coronary sinus ... converted to sinus rhythm with adenosine or rapid atrial pacing, thus ruling out junctional ectopic tachycardia Despite treatment with amiodarone, the episodes continued Propranolol, digoxin, and propafenone...

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Báo cáo y học: " Response of pulmonary artery intimal sarcoma to surgery, radiotherapy and chemotherapy: a case report" docx

Danh mục: Báo cáo khoa học

... abundant Pathological findings of surgical specimen show abundant spindle cells Hematoxylin and eosin stain ×100 Thirteen days after radiotherapy, the patient complained of pain in the right upper ... and seeding of emboli [1,2] Intimal sarcoma is a rare tumor, and the incidence of PA intimal sarcoma is almost twice that of sarcomas of aortic origin It mainly occurs in adults within the age ... journal Competing interests Patients with intimal sarcoma present with various symptoms The most common initial symptoms are dyspnea, hemoptysis and chest pain [1] Due to the rarity and insidious...

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Báo cáo y học: " Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery" pps

Danh mục: Báo cáo khoa học

... Hoechst staining (Sigma, Saint-Quentin Fallavier, France) Then, ECs in the proximal and distal PA were counted in a blinded fashion by two investigators working independently from each other, and ... added for hour at 37°C Sections were washed in working strength Stop/ Wash buffer for 10 minutes Pre-warmed working strength anti-digoxigenin conjugate (rhodamine) was added to the sections and incubated ... Pentoxifylline administration to patients with ischemic cardiomyopathy inhibited proinflammatory cytokines and reduced apoptosis by decreasing TNF-α and Fas concentrations in plasma [15] Pentoxifylline probably...

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Báo cáo y học: " Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells" docx

Danh mục: Báo cáo khoa học

... production Cells, seeded in 24-well plates (2 × 104 cells/well), were cultured in medium containing 10% FBS for at least days before being serum-deprived for 24 h Cells were incubated in fresh serum-free ... 0.1% Triton X-100 After fixation in 25% isopropanol and 10% acetic acid for 10 min, gels were stained in 0.25% Coomassie blue for 1–2 h and destained in fixing/destain solution until bands of activity ... subsequently incubated in fresh medium containing 0.25 µCi/well [3H-methyl]thymidine, in the presence of PDGF-BB (5–10 ng/ml) PDE inhibitors and/or prostacyclin analogues were added 30–45 before the...

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Báo cáo y học: " Pro/con clinical debate: Pulmonary artery catheters increase the morbidity and mortality of intensive care unit patients" potx

Danh mục: Báo cáo khoa học

... hemodynamic finding would, in fact, change treatment Summary Invasive hemodynamic monitoring may have a role in the management of a select group of ICU patients, if done by properly trained physicians ... ones likely to show benefit In conclusion, in the present scenario a PAC inserted by an intensivist trained in its use and utilizing protocol-directed responses would not increase mortality and morbidity, ... Stephen E Lapinsky As Guy Richards points out, both clinical assessment and PAC measurement are associated with errors in evaluation and management Clinical assessment is sometimes inaccurate in the...

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Báo cáo khoa học: "The concentration of oxygen, lactate and glucose in the central veins, right heart, and pulmonary artery: a study in patients with pulmonary hypertension" ppt

Danh mục: Báo cáo khoa học

... respectively, in five patients with cardiogenic shock (cardiac index 1.7 l/min per m2) Pulmonary arterial SO2 was nearly equal to the computed mean SO2, indicating a predominant role for IVC SO2 in the formation ... taken to verify with fluoroscopy the position of the catheter at each sampling site and the blood sampling procedure was performed within a span of min, with no changes noted in heart rate or blood ... reported in published studies measuring SO2 in the central veins, the right heart, and pulmonary artery in humans [27-31] With the exception of a subset of eight patients who were 'not in shock',...

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Báo cáo y học: " Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study" ppt

Danh mục: Báo cáo khoa học

... decreased in none of the fluid challenges resulting in increased SV, and in 44% of those in which SV did not increase (P = 0.0003) EDV increased in 28% of fluid challenges resulting in increased ... any acute increase in central venous pressure in response to volume loading suggests an increase in preload and should result in an increase in stroke volume if the heart is operating in the volume-responsive ... predict which patients will respond to fluid administration [12,14] We tested this in a clinical context in which fluid infusion is unavoidable (that is, in patients with septic shock and in patients...

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Báo cáo y học: "Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study" doc

Danh mục: Báo cáo khoa học

... challenges with concomitant increase in central venous pressure; thin solid line, line of identity during an endotoxemia-induced acute increase in pulmonary artery pressure In hemorrhage-induced ... compared with baseline †P < 0.05 compared with endotoxin plus bleeding ‡ P < 0.05 compared with bleeding §P < 0.05 compared with endotoxin (paired t test) ¶P < 0.05 compared with baseline Table ... showing fluid challenges in endotoxemia preceding hemorrhage Solid line, all fluid challenges; dashed line, fluid challenges with concomitant increase in central venous pressure; thin solid line,...

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Báo cáo y học: "Cross-comparison of cardiac output trending accuracy of LiDCO, PiCCO, FloTrac and pulmonary artery catheters" docx

Danh mục: Báo cáo khoa học

... platelets or 0.9% saline given over < 30 min) Inotrope (any Δ > 0.01 μg/kg/min in epinephrine or > μg/kg/min in dopamine or dobutamine infusion) 10 Combination of any two or more interventions simultaneously ... L/min 0.04 L/min -0.87 L/min 2.11 L/min 0.27 L/min -1.57 L/min 1.46 L/min -0.10 L/min -1.65 L/min 1.30 L/min 0.30 L/min -0.70 L/min 1.59 L/min -0.27 L/min -2.13 L/min Figure Bland-Altman analysis ... http://ccforum.com/content/14/6/R212 2.67 L/min C O td-LiD C O C O (L/m in) 0.09 L/min -2 -2.49 L/min -4 -6 COtd 1.54 L/min -0.10 L/min -2 -1.75 L/min -4 10 12 CCO 1.80 L/min 0.49 L/min -0.81 L/min...

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Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf

Danh mục: Sức khỏe người cao tuổi

... of aging and remained unexplained; the role of an increase in closing volume with aging was not supported by these data This elegant study included, unfortunately, a small number of older patients ... maximal inspiratory flow values decrease with aging Because lung deposition of inhaled drugs is flow dependent with available powder-inhaling devices, determination of maximal inspiratory flow in ... may not be attained in very elderly patients With the Turbuhaler, for instance, lung deposition at an inspirator flow of 30 L Á minÀ1 is approximately half that obtained at 60 L Á minÀ1, although...

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Sputum smear negative pulmonary tuberculosis: sensitivity and specificity of diagnostic algorithm docx

Danh mục: Sức khỏe giới tính

... smear-negative for AFBs (ZN stain); and who gave a written informed consent to participate in the study and for HIV testing were included into the study Patients with known tuberculosis or who had PTB in ... atypical due to other infections in HIV positive patients [4] In fact, substantial numbers of patients are treated for tuberculosis without definitive diagnostic criteria [5] With the advent ... and physical examination was done by a study clinician and the findings were recorded on a clinical record form The investigators did not interfere in the treatment of these patients The treatment...

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Báo cáo khoa học: Heme oxygenase-1 ⁄p21WAF1 mediates peroxisome proliferator-activated receptor-c signaling inhibition of proliferation of rat pulmonary artery smooth muscle cells pot

Danh mục: Báo cáo khoa học

... [27,28] The CDK inhibitor protein ⁄ kinase inhibitor protein family includes p21WAF1, p27Kip1, and p57Kip2 They halt the cell cycle in the G1 phase by binding to, and inactivating, cyclin–CDK complexes ... [26] In addition, CDK activity is modulated by a group of CDK inhibitors comprising two families of proteins: inhibitor of kinase ⁄ alternative reading frame and CDK inhibitor protein ⁄ kinase inhibitor ... Golovina et al [41] Isolated arterial rings were incubated in Hanks’ balanced salt solution containing 1.5 mgÆmL)1 collagenase II (Worthington, Lakewood, NJ, USA) for 20 After incubation, a thin...

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Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery ﬁbroblasts A role for phosphoinositide 3-kinase pot

Danh mục: Báo cáo khoa học

... whereas trypsin and tryptase activate PAR2 [12] Certain other proteases, including chymotrypsin and cathepsin G, appear to ÔdisarmÕ PAR1 by cleaving the exodomain of the receptor without inducing activation ... surrounding crypts in the jejunal mucosa are toluidine blue (pH 0.5)-positive (counterstained with eosin) Antiduodenase Ig staining is shown at low magniﬁcation in panel (b), with abundant staining ... duodenase-induced [3H]thymidine incorporation, suggesting a key role for PtdIns 3-kinase in this response (Fig 5) In contrast, PD98059, a MEK1 inhibitor, caused only a partial Ó FEBS 2002 Duodenase induces...

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LABORATORY DIAGNOSIS OF PULMONARY TUBERCULOSIS : CONVENTIONAL AND NEWER APPROACHES+ pdf

Danh mục: Sức khỏe giới tính

... (Adenosine Deaminase) important limiting factors in determining the directly in clinical samples TSA is present not sensitivity of PCR assays for M.tuberculosis in only in M.tuberculosis, but also in ... whereby certain repetitively occurring DNA sequences (insertion sequences) are identified by specific probes This results in a fingerprint highly specific for each individual mycobacteral strain This ... Isoniazid and Rifampicin with or without resistance against any other drugs” 110 N.K JAIN two days The method is still in its developmental Three widely used methods for testing stage sensitivity...

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Pulmonary Tuberculosis - Evolution and Clinical picture doc

Danh mục: Sức khỏe giới tính

... Mode of infection The disease is transmitted through inhalation of infected sputum droplets or ingestion of infected milk Primary Tuberculosis Occurs in the body when it is infected for the ... and giant cells with bacilli in the center The primary tuberculous infection usually occurs in the lung but occasionally in the tonsils or in the alimentary tract Lung 80% Intestine (enteritis ... intima , with subsequent discharge of bacilli into the blood stream leading to miliary spread Usually solitary, caseating and liquefying but can later heal by endothelial covering Can occur in...

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other reasons for heart failuresymptoms in patients with normalejection fractions