... setting of more routine decompensated heart failure, and the effect milrinone in ischemic subset ofpatients deserves further investigation Conclusion Initiation of milrinone therapy inpatients ... conclusion of study participation all patients care continued to be at the discretion of the attending physician, including inotrope administration and dosing It is well recognized that heartfailure ... Mabuchi N, Sawaki M, Kinoshita M: Interleukin-6 spillover in the peripheral circulation increases with the severity ofheart failure, and the high plasma level of interleukin-6 is an important...
... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis ofheart failure, in the ... circulating levels of tumor necrosis factor in severe chronic heartfailure N Engl J Med 1990, 323:236-236 Mann DL, Young JB: Basic mechanisms incongestiveheartfailure Recognizing the role of proinflammatory ... Iwasaki T: Increased circulating interleukin-18 inpatientswithcongestiveheartfailureHeart 2002, 88:296-7 Boerrigter G, Costello-Boerrigter LC, Burnett JC Jr: Natriuretic peptides in the diagnosis...
... interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin, galectin-3 [16-18], some of which are also important tools in the diagnosis and pathogenesis ofheart failure, in the ... circulating levels of tumor necrosis factor in severe chronic heartfailure N Engl J Med 1990, 323:236-236 Mann DL, Young JB: Basic mechanisms incongestiveheartfailure Recognizing the role of proinflammatory ... Iwasaki T: Increased circulating interleukin-18 inpatientswithcongestiveheartfailureHeart 2002, 88:296-7 Boerrigter G, Costello-Boerrigter LC, Burnett JC Jr: Natriuretic peptides in the diagnosis...
... for its usein a population of early arthritis patientsIn addition, we studied the impact of different factors on the evolution of mineral bone content in these patients, including GC use Materials ... most intriguing finding in our study was that the useof GCs has no relevant impact on bone mass inpatientswith early arthritis Earlier studies that focused on the effect of GCs on bone mass in ... Baseline 12 24 Time (months) (b) Percentage ofpatients 20 15 10 0 100 200 300 mg of prednisone/month Figure Useof glucocorticoids (GCs) inpatientswith early arthritis (a) Percentage of patients...
... patientswith acute respiratory failure Physician belief in the utility of tracheostomy, patient selection and the lack of blinding may introduce bias, leading to difficulties in comparing patients ... (63%) of the 48 trauma patients had a traumatic brain injury (TBI) as their sole injury or in addition to torso and extremity injuries The remaining patients had various surgical problems including ... number of end-points in order to minimize falsely positive associations with tracheostomy We were primarily interested in the potential influence of tracheostomy on the duration of weaning and of...
... twenty (77.9%) patients were males In terms of the clinical data, over two thirds of subjects were angina The finding of high proportions of Chinese CHD patients screening positive with anxiety ... Xi'an province of China Mandarin is spoken Due to the pictorial nature of Chinese writing, both Cantonese and Mandarin-speaking Chinese would be able to read the Chinese version of the HADS In Europe, ... artifactual of the original translation process, which may also explain inconsistencies between the underlying factor structure of the instrument between Mandarin-speaking Chinese CHD patientsin the...
... number of missing scores in the SF-6D; imputing a value for missing items in a SF-36 domain using the mean value for that domain This way, the amount of missing scores in the SF-6D due to incomplete ... domain scores of the SF-36 allows a certain amount of missing scores, which are imputed with the mean value of the completed items of that domain [5] We used that technique to reduce the number of ... number of missing baseline and change scores Normality of distributions was tested with Shapiro-Wilk's W test [18] The ceiling effect of each domain was assessed by computing the percentage of patients...
... measures in combination in a single model to predict the EQ-5D index In this case, disease severity was taken into account using a single variable, and more implicitly from the point of view of stage ... where a model mapping clinical measures on to the EQ-5D index explained 37% of the variability in the EQ-5D index and also performed poorly in individuals with EQ-5D index values of about 0.4 or ... Page of 13 other using clinical measures to map to the EQ-5D index [13,15] This study aimed to use individual patient data to derive mapping models for the EQ-5D index in cardiac patients with...
... hundred forty-nine (94%) patients were intubated within six hours of ICU admission and eight others were intubated within 24 hours of admission All 159 patients were intubated because of septic shock; ... ketamine (1), and fentanyl (1) Two patients had inhalational induction of anaesthesia with sevoflurane because of coexisting acute upper airway obstruction Sixteen patients received no agent to induce ... (96%) were intubated within 24 hours of the onset of shock, an additional five were intubated within 48 hours, and in one patient tracheal intubation occurred 78 hours after the onset of sepsis...
... Only initial TOI was a clinically meaningful predictor of follow-up TOI, with a SD increase (12.7 points) in initial TOI scores corresponding to a 6.4 point increase in follow-up TOI scores Initial ... HRQL The percent ofpatientswith a clinically meaningful decline in EWB scores from the initial to follow-up survey was exactly the same as the percent with a clinically meaningful improvement ... more patients had a meaningful improvement than decline in TOI scores, but fewer patients had a meaningful improvement than decline in SWB scores EWB scores were the most stable, with 47.6% of patients...
... symptomatology, including pain and itching, combined with concerns about the appearance of one's skin can substantially affect a patient's psychological well-being and can result in emotional distress, ... race in the data analyses Instruments used for assessment of health-related quality of life The SF-36 Health Survey (Version 1) is a 36-item general health status instrument often used in clinical ... (Version 1), which was used in the MEPS survey included in this analysis, contains 12 items from the SF-36 Health Survey, with or items measuring each of the concepts included in the SF-36 SF-12...
... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... validated in samples combining patientswith a range of eye conditions including cataracts, macular degeneration, diabetic retinopathy, glaucoma, or low vision from any cause [25,35] In the current ... indication of the precise areas of HRQL and functioning that may tend to change along with visual acuity inpatientswith diabetic retinopathy SAS statistical software version 8.2 was used for...
... quality of life ofpatients participating in the current study seem to be in accordance with scores ofpatientswith fibromyalgia participating in other studies For patientswith fibromyalgia in the ... decreased pain tolerance and a higher level of disability Although the construct of fear of injury is also applicable inpatientswith fibromyalgia, the mean score on fear of injury ofpatientswith ... hyperactivity can eventually cause chronic pain and long term false straining of the muscles eventually can result in chronification of pain In accordance with the hypothesis of Hasenbring, Van Houdenhoven...
... underpin balance impairment in persons with PD That is, combining an extended battery of clinical performance tests, subjective ratings of fear of falling and laboratory assessments that investigate ... assessments of fear of falling have not previously been included in studies when investigating the effect of STN stimulation In the present study, the patients rated their fear of falling as less ... extended with three additional activities: getting in and out of bed, grooming and toileting [38] The FES(S) was originally tested in stroke patients, but the 13 item version has been used when investigating...
... psoriasis patients Various factors may be attributed to the lower QoL in psoriasis patients The chronic and recurring nature of this disease often brings about a feeling of hopelessness in terms of ... "Infliximab treatment results in significant improvement in the quality of life ofpatientswith severe psoriasis: a double-blind placebo-controlled trial" (2005) [43] Intravenous infusions of ... a valid instrument for examination of social and psychic burdens of psoriasis The recording of stigmatization feeling and of quality of life determines different supplementary aspects of the illness-related...
... and inform clinical decision making Utility assessment is a particularly appealing quality of life measure because it incorporates all aspect of health into a single number (between and 1) with ... perfect health is determined and used to derive the utility of the health state in question [22] The SG instrument was originally administered faceto-face with trained interviewers, but the more ... making them an informed and realistic patient population facing these decisions Although patientswith HGD or prior HGD were excluded, patientswith prior LGD were included The description of...
... prognosis in seriously ill patients admitted to intensive care units or survival inpatientswith terminal illness, usually cancer [14-19] A better understanding of physicians' prognostic estimates in ... the physician's views of disease severity as part of a longitudinal study of HRQoL in a large cohort ofpatientswith chronic cardiac or pulmonary disease Using these data, in this paper we address ... subjective income reports are consistent with more objective measures, including the fact that 43.6% of the patients reported having annual incomes below $15,000 Nearly 84% of the patients reported...
... presented in Table The results of the scales of SF-36 between the two time intervals inpatientswith anogenital warts and in the control group are presented in Table In this Table, the scores of the ... participated in generating and gathering the data the data and in writing the manuscript EN participated in generating the data and in writing the manuscript MH participated in the design of the study ... participated in generating and in gathering the data of the study HP participated in generating and gathering the data of the study AK participated in the design and coordination of the study All authors...
... (worse) scores in all domains of the SGRQ, than the men There were no differences in any domain for Stage III and IV patients This is an interesting finding considering that female with FEV1%
... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... validated in samples combining patientswith a range of eye conditions including cataracts, macular degeneration, diabetic retinopathy, glaucoma, or low vision from any cause [25,35] In the current ... indication of the precise areas of HRQL and functioning that may tend to change along with visual acuity inpatientswith diabetic retinopathy SAS statistical software version 8.2 was used for...