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maintenance regeneration and renewal development of a t cell based vaccination against neurodegeneration

Báo cáo hóa học:

Báo cáo hóa học: " Research Article Design and Experimental Evaluation of a Vehicular Network Based on NEMO and MANET" pdf

Hóa học - Dầu khí

... are then postprocessed by the AnaVANET software AnaVANET is a Java application which traces all data packets transmitted or forwarded by mobile routers It thus detects packet losses and can generate ... generate both end-to-end and per-hop statistics, as well as join these measurements with transport level statistics from the traffic generation tool AnaVANET generates XML files with statistics at a ... to the latter mark to either the NEMO or MANET routing tables Packets matched with a NEMO routing table are transmitted to the tunnel bound to the HA, while packets matched with the MANET table...
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Báo cáo khoa học:

Báo cáo khoa học: "Development of a monoclonal antibody-based co-agglutination test to detect enterotoxigenic Escherichia coli isolated from diarrheic neonatal calves" pptx

Báo cáo khoa học

... seidobitna eseht ,seititnauq etauqeda ni ytilibaliava raluger eht dna snoitaredisnoc cimonoce morf trapA negitna 99K ot seidobitna lanolconom gniraperp ot segatnavda ynam era erehT noitavresbo siht ... gnitset ni desu saw tset noitanitulgga-oc ehT Co4 ta derots nehw shtnom naht erom rof dna )Co93 ot Co02( erutarepmet tneibma ta derots nehw shtnom rof elbats erew suerua S detaoc-ydobitnA yassa ... etahpsohp tsniaga dezylaid dna )noitarutas %54( etaflus muinomma htiw detatipicerp ,g × 000,5 ta noitagufirtnec yb detsevrah erew seidobitna deterces ehT sksalf erutluc-eussit egral ni detagaporp...
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báo cáo khoa học:

báo cáo khoa học: "Development of a primary care-based complex care management intervention for chronically ill patients at high risk for hospitalization: a study protocol" potx

Báo cáo khoa học

... conditions We have to understand how professional and patient behaviour as well as care organization contributes to avoidable hospitalizations and to what extent care management may be able to ... Patients] patient chart Ejection fraction [CHF Patients] patient chart Current Medication patient chart Page of discussing a detailed description of the planned care management intervention (i.e., paper ... and treatment patterns (analysis of claims data) as well as healthcare needs and resources (patient survey and chart review) This comparison may help us to develop an optimal approach to identify...
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Báo cáo y học:

Báo cáo y học: " Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein" ppsx

Báo cáo khoa học

... 5'-ggatggcgagctttaggttggGTGTGCTGTCCccaatctgaagcttgccatccTTTTT-3' for Dlg1-1, 5'ggatgtttaggagtataagttGTGTGCTGTCCaacttatgctcctgaatatccTTTTT-3' for Dlg1-3, 5'-gaaagaacgagcccgattaTTCAAGAGAtaatcgggctcgttctttcTTTTT-3' for hDlg1-1, 5'gtgttcagtctgtacgagaTTCAAGAGAtctcgtacagactgaacacTTTTT-3' ... 5'gtgttcagtctgtacgagaTTCAAGAGAtctcgtacagactgaacacTTTTT-3' for hDlg1-3, 5'gagtggatgccacgacggtttGTGTGCTGTCCaaatcgtcgtggtattcactcTTTTT-3' for CAT, 5'-ggcctttcactgctcctgcgaGTGTGCTGTCCtcgtaggagtagtgaaaggccTTTTT-3' ... suggested that inactivation of Dlg1 is a critical step for the transforming activity of Tax1, and Tax1 through PBM inactivates inhibitory activity of Dlg1 to induce transformation of CTLL-2 cells...
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Báo cáo y học:

Báo cáo y học: "Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)" pps

Báo cáo khoa học

... Nevertheless, these data suggest that potentiation of the immune response against viral proteins such as Tax may be an attractive way to treat ATL patients [94] Such strategies may enable preventive treatment ... I tax Int J Cancer 2005 Yamaoka S, Inoue H, Sakurai M, Sugiyama T, Hazama M, Yamada T, Hatanaka M: Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the ... Kawakami H, Tomita M, Matsuda T, Ohta T, Tanaka Y, Fujii M, Hatano M, Tokuhisa T, Mori N: Transcriptional activation of survivin through the NF-kappaB pathway by human T- cell leukemia virus type...
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Báo cáo y học:

Báo cáo y học: " PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line" ppsx

Báo cáo khoa học

... http://www.retrovirology.com/content/2/1/46 PBM ETEV Tax1 Tax Tax2B C Tax2B+C ETEV PBM: PDZ Domain Binding Motif Tax35 1A EAEV Tax35 3A ETEA Figure Structure of Tax1, Tax2B and their mutant proteins Structure of Tax1, Tax2B and ... Tax2B plasmid and the antibody against Tax2B We thank the Takeda pharmaceutical company for providing recombinant human IL-2 We also thank Sayoko Takizawa and Chika Yamamoto for the excellent ... characterized (Figure and Table 1) [33] The Tax∆C gene contains a C-terminal four-amino acid deletion abrogating PBM in Tax1 Tax35 1A and Tax35 3A are substitution mutants of Tax1 PBM, at amino acids...
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Development of a virtual reality based microsurgery trainer

Development of a virtual reality based microsurgery trainer

Tổng hợp

... such that the adaptor can be bolted onto the needleholder adaptor The DVRT adaptor is made up of a pair of swiveling holders with a through-bore The core and shaft of the DVRT are tightened to the ... nature, thus the adaptors 21 must be able to rotate to maintain a smooth sliding motion between the shaft and the core of the DVRT Similar to the stylus adaptor, the holders are pivoted onto the ... reference to a the center of mass of the body), R (t) is a 3x3 Rotation matrix defining the total rotation (about the center of mass) experienced by the object in world space at time t, And x (t) is the...
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Design improvements and performance testing of a biomass gasifier based electric power generation system

Design improvements and performance testing of a biomass gasifier based electric power generation system

Báo cáo khoa học

... rate Quantity and calorific value of fuel Quantity and calorific value of producer gas Ultimate and proximate analysis of fuel Gas analysis Gas temperature at various points Air temperature at ... inlet Gas temperature at the outlet Air temperature at the inlet Air temperature at the outlet Tube bank arrangement Number of passes Flow direction of air and gas Vibrator motor specification ... gas The amount of the energy recycled into the reactor and the heat loss are estimated by measuring the temperature of air and gas, at the inlet and the outlet of the heat exchanger 5.1 Estimation...
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báo cáo hóa học:

báo cáo hóa học:" Use of a novel cell-based fusion reporter assay to explore the host range of human respiratory syncytial virus F protein" ppt

Hóa học - Dầu khí

... insoluble material and immunoprecipitated by incubation with a saturating amount (as determined by prior titration) of a cocktail containing 1.5 µgs of anti-F mAbs and protein -A agarose beads (Invitrogen, ... propose that this assay also has utility in the identification and characterization of inhibitors of HRSV entry for the development of specific agents to prevent and treat HRSV infections We have ... early promoter (pGL3-control), and relative luciferase activity was measured To account for potential differences in host cell transcription factors that mediate activation of the reporter plasmid,...
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Development of human stem cell based model for developmental toxicity testing

Development of human stem cell based model for developmental toxicity testing

Y - Dược

... is activated, it can autoregulate itself and activate BMP in the extraembryonic ectoderm The activated BMP will then induce Wnt in the adjacent epiblast [30] Wnt signals can concentrate Nodal to ... concentration is higher than the human therapeutic Cmax (A) A test compound was predicted as a teratogen when the teratogenicity potential concentration is lower than the human therapeutic Cmax ... mechanical polarization by micropatterning alternating strips of MatrigelTM (MG) and Ecadherin tagged with human Fc fragments (EcadFc) on substrate (a) Schematic illustrating asymmetry in cell adhesion...
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Báo cáo y học:

Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"

Y học thưởng thức

... Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: longterm results from the Diabetes and ... according to the ACC/AHA criteria [26,27] Statistical analyses MedCalc™ v 9.6.2.0 (MedCalc Software, Mariakerke, Belgium) statistical software was used for all statistical analyses Categorical ... metabolism and to timely start treatment Abbreviations ADA: American Diabetes Association; DM: diabetes mellitus; GD: gestational diabetes; IFG: impaired fasting glucose; IGT: impaired glucose tolerance;...
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Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Báo cáo khoa học

... Marine Pests Priorities and hazards for Economies  Variable levels of activity and management capability  Ships’ ballast water and hull fouling are the most important vectors  International shipping, ... shipping, aquaculture and biodiversity are most threatened values  Amount of commercial shipping and number of trading partners affecting pathway strength  A limited number of IMP have been identified ... MRCWG have a role in liaising with IMO, FAO, NACA to enhance the effectiveness of existing instruments within APEC  Institutional arrangements for managing the marine environment is fragmented...
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Tài liệu Báo cáo khoa học: Development of a new method for isolation and long-term culture of organ-specific blood vascular and lymphatic endothelial cells of the mouse pdf

Tài liệu Báo cáo khoa học: Development of a new method for isolation and long-term culture of organ-specific blood vascular and lymphatic endothelial cells of the mouse pdf

Báo cáo khoa học

... former, and LTA–M2F, 5¢-CAGCTGTTTTGCTTGAATTATG-3¢ and LTA–2R, 5¢-GAATTCATTATGTTTCAGGTTCA GGGG-3¢ for the latter The PCR products were cloned into the EcoRV site of pZErO-2 (Invitrogen) A XhoI–PvuIIdigested ... tsA5 8T Ag cDNA carrying the A4 38V mutation were PCR-amplified from COS-7 cDNAs using the following primers: LTA-1F, 5¢-CTC GAGATGGATAAAGTTTTAAACAGAG-3¢ and LTA1R, 5¢-TGAAGGCAAATCTCTGGAC-3¢ for the ... plated onto gelatin-coated plastic dishes and cultured at 33 °C (day in Fig 1) For the initial weeks, primary cells, including both tsA5 8T Ag-negative cells (primarily fibroblasts) and tsA5 8T Ag-positive...
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Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

Báo cáo khoa học

... AAAAAATGGAGCGAAGGAACCACAG-3¢) and (5¢-AG CTGCCTGCAGGTCGACTCTAGAGGATCCTAACCAA TTTTGCTGCC-3¢); for OR17-40 (5¢-CGTCAAGGAG AAAAAACCCCGGATCTAAAAAATGGAGCAGAAAC TCATCTCTGAAGAGGATCTG-3¢) and (5¢-GCATG ... CCTGCAGGTCGACTCTAGAGGATCTCAAGCCAGT GACCGCCTCCC-3¢); for Golf (5¢-GGTACCGCTGCAA TGGGGTGTTTGGGCAAC-3¢) and (5¢-GCGGCCGCCT CAGATCACAAGAGTTCGTACTGC-3¢); for Ga15 (5¢-AT GGCCCGGTCCCTGACTTGG-3¢) and ... yeast expressing SSTR2 as a control activity By taking advantage of structural and functional similarities between yeast and mammalian GPCR signaling pathways, this assay enables the quantitative...
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A STUDY OF THE EFFECTS OF CORRUPTION ON ECONOMIC AND POLITICAL DEVELOPMENT OF ARMENIA doc

A STUDY OF THE EFFECTS OF CORRUPTION ON ECONOMIC AND POLITICAL DEVELOPMENT OF ARMENIA doc

Cao đẳng - Đại học

... motivation, namely that of private gain at public expense." So he stated the concept of corruption in a way that constitutes a break of law or of standards of high moral conduct Jacob Van Klavaren ... evasion and poor tax administration In many cases tax collections is much lower than estimated tax 31 bases Tax evasion takes place when taxpayers manipulate their accounts or their declarations to ... most important input in the process of production and transformation that is called economic development First corruption weakens tax administration and can lead to tax evasion and improper tax...
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Báo cáo khoa học: Cleavage site analysis of a serralysin-like protease, PrtA, from an insect pathogen Photorhabdus luminescens and development of a highly sensitive and specific substrate pdf

Báo cáo khoa học: Cleavage site analysis of a serralysin-like protease, PrtA, from an insect pathogen Photorhabdus luminescens and development of a highly sensitive and specific substrate pdf

Báo cáo khoa học

... of PrtA cleavage site specificity, and kinetic characterization of PrtA activity on the new substrate Results and Discussion Identification of PrtA cleavage sites in biological peptides To obtain ... PrtA Peak areas were normalized with the internal standard, and the degree of cleavage was calculated from the reduction in the normalized area of the substrate peaks For the identification of ... substrate and the activity of PrtA After determining the optimal excitation and emission wavelengths, the molar fluorescence value and the calibration of the inner filter effect (see Experimental...
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Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Báo cáo khoa học

... cytokines, as well as alternative modes of development The data that are accumulating suggest that the role of Itk in the development and function of iNKT cells and cd T cells seems to be quite ... development at the initial stages of maturation [28], and both mice deficient in Itk and those that express a transgene for PLZF have a developmental block in stage of iNKT cell maturation, all of which ... cells share portions of their developmental program with conventional T cells iNKT are a subset of NKT cells Itk and i NKT and cd T cells that largely express an invariant ab TCR Both iNKT and conventional...
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Báo cáo sinh học:

Báo cáo sinh học: " Development of a real-time RT-PCR and Reverse Line probe Hybridisation assay for the routine detection and genotyping of Noroviruses in Ireland" pdf

Hóa học - Dầu khí

... GTG AGT TCT TGC TYG A TTC CCC TGG AGA AGT ACT CCT CGA ACT AAA TCC ATA CCT AGC ACAC CAG TGG CGG GAC AAA CCA AC CTC TCC TGG AGA ACT CCT ACT TGA T GAA GTC TTG CCT TTA GAG CCC GTC CAG TTG CGG GAG ... GI/8 TCT TGC AAT GGA TCC TGT RGC RG GAA CCC GTG GCY GGG CCA AC CCA GAG GCA AAY ACA GCT GAG TGA CCC TGT GGC TGG CTC CTC ATG CTG AAC CAC TGC CWC TTG AT CAA ATT TCA ATG GAY CCT GTT GCG GGT AGT GGG ... GAT TAG AGC A CAA TGG CGC TAG ABC CAG TGG CG GAC GCC AAC CCA TCT GAT GGG TC GGT GGG GGC GTC TTT AGC C CTC AAT CGC AGC TCC TGT YGT GCA TCG CTG GCG ACA CCA GTT G TCA ACC ATG AGG TCA TGG CCA TA CCC...
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báo cáo hóa học:

báo cáo hóa học: " Development and preliminary evaluation of a quality of life measure targeted at dementia caregivers" doc

Hóa học - Dầu khí

... marital status, ethnicity, education) than were available for the initial 51 subjects Selected patient variables (age, marital status, ethnicity, and education) for the initial set of 51 caregivers ... ethnicity and education and patient age, gender, marital status, ethnicity and education where these data were unavailable or missing Page of 12 (page number not for citation purposes) Health ... the estimates were wide, and while we attempted to identify a subset less likely to have actually had change in quality of life by setting a cap on the testretest interval and restricting to those...
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