m looking right at the other half of me

Tài liệu New York Times - Looking Back At The Crash Of 1929Pdf doc

... conferred with members of the board relative to the government's position. Late in the day the board was reported to be awaiting a report from a meeting of the directorate of the New York ... ``Playing the stock market has become a major American pastime,'' reported The Times in a magazine article published on March 24, 1929. The article noted that the number of brokerage ... steadied momentarily. Steel common was then selling on the floor of the Exchange at 193 1/2. A Morgan broker on the floor of the Stock Exchange started bidding for Steel, and the market leader immediately...

Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"

Danh mục: Y học thưởng thức

... lumens were smaller in the high fat diet group than in the normal group. Vessel wall is in the condition of rugosity and the yellow athero-matous plaques were found in the lumens of high fat ... for ho-mogeneity of variances. If the data failed to meet the requirements for the parametric t test, a Mann-Whitney U test was performed. A value of P<0 .05 was considered statistically ... statin Introduction Atherosclerosis is a slow and complicated pa-thological process. Vascular smooth muscle cell (VSMC) proliferation is one of the important features of atherosclerosis. The...

LECTURE SLIDES ON NONLINEAR PROGRAMMING BASED ON LECTURES GIVEN AT THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MASS DIMITRI P. BERTSEKAS

Danh mục: Tin học văn phòng

... problemOPTIMAL CONVERGENCE RATE• The value of αkthat minimizes the bound isα∗=2/ (M + m) , in which casexk+1xk≤ M − m M + m 0α1|1 - M ||1 - m |max {|1 - m| , |1 - M| } M - m M ... M| } M - m M + m 2 M + m 1 M 1 m 2 M Stepsizes thatGuarantee Convergence• Conv. rate for minimization stepsize (see text)f(xk+1)f(xk)≤ M − m M + m 2• The ratio M/ m is called the condition ... Computation by iterative algorithms− Iterative descent− Approximation methods− Dual and primal-dual methodsLOCAL AND GLOBAL MINIMAf(x)xStrict LocalMinimumLocal Minima Strict GlobalMinimumUnconstrained...

Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

Danh mục: Báo cáo khoa học

... multienzyme complex;thiamin diphosphate; limited proteolysis; enzyme mecha-nism. The family of 2-oxo acid dehydrogenase (2-OADH) multi-enzyme complexes contains three members: the pyruvatedehydrogenase ... group of the substrate [for a detailed formulation of the mechanism to date, see [44]). The importance of this region is emphasized by the reports of clinically deleterious mutations in the human ... (Fig. 3). The reaction mixture with E1 was incubatedfor exactly 10 min at the relevant temperature and the catalytic activity at that temperature was then determined. The inactivation temperatures...

Tài liệu The Proof is in the Pudding - A Look at the Changing Nature of Mathematical Proof doc

Danh mục: Cao đẳng - Đại học

... speculation.Saunders Mac Lane0.1 What is a Mathematician?A well-meaning mother was once heard to tell her child that a mathematicianis someone who does “scientiﬁc arithmetic”. Others think that a mathemati-cian ... convincing another mathe-matician that a given statement (the theorem) is true. Thus a proof can takemany diﬀerent forms. The most traditional form of mathematical proof isthat it is a tightly ... someone that something is true.”But it is not a mathematical proof.0.2. THE CONCEPT OF PROOF 9As a result of these questions, ancient mathematicians had to think hardabout the nature of mathematical...

Báo cáo " Sequence stratigraphy of Quatemary depositions on the land and at the continental shelf of Vietnam " pot

Danh mục: Báo cáo khoa học

...

Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc

Danh mục: Báo cáo khoa học

... part of the initial time-course.GST–hGK ﬂuorescence measurementsITF measurements were performed on a Perkin-Elmer LS-50B spectrometer (1-cm pathlength) at 25 °C in a buffercontaining 20 mm Hepes, ... Moates M, Magnuson MA & MatschinskyFM (1999) Mutants of glucokinase cause hypoglyca-emia- and hyperglycaemia syndromes and their analysisilluminates fundamental quantitative concepts of ... aggregation of the protein (data not shown). This instability of the pro-tein precluded an estimate of equilibrium thermody-namic parameters, and thus also measurement of the effect of ligands...

RESULTS BRIEFING SESSION: THE FIRST-HALF OF THE FISCAL YEAR ENDING MARCH 31,2009 pptx

Danh mục: Tài chính doanh nghiệp

... forward -looking statements about the future performance of SQUARE ENIX GROUP. These statements are based on management's assumptions and beliefs in light of information available to it at the ... the time these material were drafted and, therefore, the reader should not place undue reliance on them. ,, pAlso, the reader should not assume that statements made in this document will ... EUR1=JPY150*Average rates for the first -half period ended Sep. 30, 2008: USD1=JPY106.23, EUR1=JPY162.12Implementation of Holding Company SystemImplementation of Holding Company SystemCurrent Structure(from October...

Báo cáo khoa học: Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme pot

Danh mục: Báo cáo khoa học

... spectral properties of the Phe501 variants suggested thatthis residue could affect the FAD environment, modulating the catalyticrate of the enzyme. Finaly, L315 affects the enzyme kcat, although ... conﬁrm the purity of the enzyme.AAO activity and kineticsAAO activity was measured spectrophotometrically bymonitoring the oxidation of veratryl alcohol to veratralde-hyde [9]. The reaction mixture ... contained 8 mm veratrylalcohol in air-saturated 100 mm sodium phosphate, pH 6.0.One activity unit is deﬁned as the amount of enzyme con-verting 1 lmol of alcohol to aldehyde per minute at 24 °C.Steady-state...

Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx

Danh mục: Quỹ đầu tư

... percent of the fund market at end June 2011, with the remaining 27 percent composed of non-UCITS. Table 7. Net Assets of the European Investment Fund IndustryMembers EUR m Shar e EUR m % chg ... DDoo m miicciilliiaattiioonn The combined assets of the investment fund market in Europe, i.e. the market for UCITS and non-UCITS, edged slightly lower in the second ... amounted to EUR 48 billion during the first half of 2011, slightly behind the EUR 55 billion recorded in the first half of 2010. Long-term UCITS attracted EUR 87 billion during the first half...

Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf

Danh mục: Quỹ đầu tư

... the other hand, money market funds in both countries recorded negative flows. Luxembourg also suffered from significant net outflows from equity funds. Of the other large domiciles, the UK attracted ... UCITS, this segment of the business accounted for almost 71 percent of the fund market at end June 2012, with the remaining 29 percent composed of non-UCITS. Table 7. Net Assets of the European ... assets of 1.7 percent during the quarter. Over the first half of 2012, total net assets of UCITS have increased by 5.6 percent. The number of UCITS at end June 2012 stood at 35,766, compared...

Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot

Danh mục: Báo cáo khoa học

... mediators of the hormone were performed on the same cell sam-ple from the same individual. Responses for the differ-ent signal mediators are therefore directly comparable. The results demonstrate ... incubations were terminated by separating cells frommedium by centrifugation10through dinonylphtalate (5000 gfor 3 s at room temperature). The cells were dissolvedimmediately in SDS and 2-mercaptoethanol ... FEBScell volume (mean ± SE, n ¼ 5), varied (118 to255 nmolÆmin)1ÆL)1) from individual to individual. The maximal rate of glucose uptake in the fat cells from the group of male patients with...

Báo cáo khoa học: Do N-terminal nucleophile hydrolases indeed have a single amino acid catalytic center? Supporting amino acid residues at the active site of penicillin G acylase pptx

Danh mục: Báo cáo khoa học

... penicillin G amidase –a member of the Ntn (N terminal nucleophile) hydro-lase family. Croatica Chim Acta 73, 901–908.3 Perakyla M & Kollman PA (1997) A simulation of the catalytic mechanism of aspartylglucosaminidase ... of the catalytic mechanismKeywordscatalytic mechanism; Hammett plot;N-terminal nucleophile (Ntn) hydrolase;penicillin G acylase; quantum mechanical(QM) and molecular mechanical (MM)modelingCorrespondenceD. ... 380 nm). The decrease of PGAactivity as a function of the amount of the inhibitorwas used to calculate the molar concentration of the enzyme [24].Synthesis of substrates for PGAN-(4-methoxyphenyl)-2-phenylacetamide,...

Báo cáo khoa học: Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase pptx

Danh mục: Báo cáo khoa học

... 10 m Mmagnesium acetate, 60 l M [c-32P]-ATP (Amersham, UK), 25 n M of the catalyticsubunit of PKA and 4 l M of hPAH. The reaction wasperformed at 30 °C, and at timed intervals, aliquots of ... (full-length form) and dimeric form (the trun-cated catalytic core enzyme) were isolated by size-exclusionchromatography [23].Protein measurements The concentration of puriﬁed enzyme forms was measuredby ... ngÆmm)2(0.48 pmolsubunitÆmm)2) of tetrameric wt-hPAH was immobilized to the dextran matrix of the sample surface, and a slightlylower amount of the dimeric catalytic core enzymehPAH(Gly103–Gln428)...