epidermidis and staphylococcus aureus
Báo cáo y học: "The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics" ppt
... drugs labeled as high and low, and the denominator is simply the difference between the standard error for high and low Welch’s t-statistic was used to compute P values, and proteins with P < ... transcription factors and their associated targets in the yeast regulatory network, relationships between gene properties such as expression and binding status and breast cancer type, and finally using ... for both AR and ABsensitive proteins and in DNA binding for AR and hydrophilicity-sensitive proteins In addition, charge-sensitive proteins showed an enrichment in transferase activity and MlogP...
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Tài liệu Báo cáo khoa học: Molecular characterization of Arabidopsis thaliana PUF proteins – binding specificity and target candidates doc
... NRE(A+B)); and in both Box A and B, NRE(A–B–) (C) Qualitative analysis of LacZ reporter activation in the interaction of APUM-2 and APUM-7 with NRE WT and NRE mutants The iron responsive element RNA and ... human and mouse possess two; and Drosophila and Dyctiostelium have only one member [5] Recently, new studies have revealed the presence of ten, two and one homologs in Trypanosome, Plasmodium and ... positions 12, 13 and 16, similar to human and Drosophila Pumilio On the other hand, the amino acids in these positions in APUM-7 to APUM-12 are more similar to those found in yeast Puf4 and Puf5 proteins...
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Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx
... existence of SMO5 in human normal and tumor cell lines SMO5 cDNA was subcloned and sequenced, and active protein was produced, purified and assayed for kinetic properties and substrate specificities NCI-H157 ... to inclusion bodies, and therefore was denatured and refolded prior to analysis All SMO5 protein production and purification steps were performed in parallel with SMO ⁄ PAOh1 and PAOh4 proteins ... decreases in intracellular spermine pools and increased spermidine levels in SMO1 and SMO5 cells These changes in spermine and spermidine levels in both SMO1 and SMO5 overexpressing cell lines were...
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Báo cáo khoa học: "Learning to Translate with Source and Target Syntax" pot
... bitexts, and one on two billion words of English These were smoothed using modified Kneser-Ney (Chen and Goodman, 1998) and stored using randomized data structures similar to those of Talbot and Brants ... source and target side, which reduces the number of eligible phrases Table shows an analysis of phrases extracted from human word-aligned and parsed data and automatically word-aligned and parsed ... similar to the expanded set recently used for Hiero (Chiang et al., 2009), but with bigram features (source and target word) instead of trigram features (source and target word and neighboring...
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ECONOMIC AND SOCIAL CONSEQUENCES OF DRUG ABUSE AND ILLICIT TRAFFICKING doc
... iron and steel and motor vehicles (2.8 per cent and 5.3 per cent respectively) and approximately the same size as the international trade in textiles (7.5 per cent), oil and gas (8.6 per cent) and ... Europe: Belgium, Denmark, Finland, France, Germany, Italy, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland and the United Kingdom of Great Britain and Northern Ireland Sources: UNDCP country ... specific dates and magnitudes), cases of SARM increased by a factor of in Germany and Spain, and a factor of approximately in Austria, Belgium, Italy and Switzerland In France and the United...
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Báo cáo khoa học: "Bridging Morpho-Syntactic Gap between Source and Target Sentences for English-Korean Statistical Machine Translation" pot
... particle and an objective particle , and insert them after the corresponding dependents Eugene and guitar respectively on content-words, which can deteriorate the performance of candidate ... any English words, and can simply and easily be removed by referring to their POS information The unaligned words are case particles, final endings, and auxiliary particles, and they call these ... 2005; Xia and McCord, 2004; Zwarts and Dras, 2007) Some reordering approaches have given significant improvements in performance for translation from French to English (Xia and McCord, 2004) and from...
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Báo cáo khoa học: "Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval" potx
... and Polysemy Resolution Models In the recent works, Ballesteros and Croft (1998), and Bian and Chen (1998) employ dictionaries and co-occurrence statistics trained from target language documents ... these words be CW~, CW2, , and C W m Assume the corresponding English translations of C, CW~, CW2, , and CWm are E, EW,, E W , , and EWm, respectively EWe, EW2, , and EWm form an augmented translation ... work (Bian and Chen, 1998), which combines the dictionary-based and corpus-based approaches for CEIR A bilingual dictionary provides the translation equivalents of each query term, and the word...
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the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin films
... patterns of Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti and (b) the expanded XRD patterns of (a) (2u = 5–158) Fig XPS spectra of the Ti 2p (right) and Na 1s (left) peaks of the Vis-TiO2/Ti and NaOH(X)-Vis-TiO2/Ti ... (Laforet Engineering, XD50D) and the evolved H2 and O2 were analyzed by a gas chromatograph (GC, G2800-T, Yanaco) with a thermal conductivity detector (TCD) Results and discussion Photoelectrochemical ... titanates such as A2Ti3O7 or A2Ti2O5 H2O, where A represents Na and/ or H [17] Fig shows the Ti 2p and Na 1s XPS spectra of the VisTiO2/Ti before and after hydrothermal treatment The intensity of the Ti...
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financial statement analysis Abbott Laboratories and Target
... 23.83% Property and equipment Land Buildings and improvements Fixtures and equipment Computer hardware and software Construction-inprogress Accumulated depreciation Property and equipment, net ... business are retail and credit card Target is well known for their operations in general merchandise and food items They owe their success to positive perceptions of the Target brand and they have ... retail and credit card Target is known for their operations in general merchandise and food items Their general merchandise segment includes household essentials, electronics, apparel and accessories,...
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MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION docx
... hydroxylamines and oximes and secondary amines to N-hydroxy and nitrone products Aromatic amines and amides are not substrates Thioethers can be oxidized to sulfoxides; and thiols, thioamides, and thiocarbamates ... be used as a teaching and/ or reference tool to delineate and understand the “why” and “how” with regard to the many creative uses of mass spectrometry in drug metabolism and disposition studies ... Lee, and Guodong Chen Characterization of Impurities and Degradants Using Mass Spectrometry Mike S Lee and Mingshe Zhu Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and...
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Báo cáo khoa học: Role of the plasma membrane leaflets in drug uptake and multidrug resistance ppt
... well as anionic drugs and dyes, but also neutral ⁄ basic amphipathic drugs and even oxyanions Previously, it has been assumed that the oxyanions arsenite and antimonite and the neutral ⁄ basic ... membrane is unstirred and dense with proteins Moreover, TMRM and anticancer drugs, such as anthracyclines, are positively charged and therefore bind to acidic groups in proteins and membranes Thus, ... lines MRP1 transports, on the one hand, organic anions, such as glutathione conjugates, and, on the other hand, basic hydrophobic drugs, such as daunorubicin and vincristine [14] It has been suggested...
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For Medicare Advantage Plans, Medicare Advantage Prescription Drug Plans, Prescription Drug Plans, and 1876 Cost Plans ppt
... name(s) or brand(s) of the co-branding entity or entities on its marketing materials to signify a business arrangement Co-branding arrangements allow a plan sponsor and its co-branding partner(s) ... Drug Program’s (NCPDP’s) “Pharmacy and/ or Combination ID Card” standard This standard is based on the American National Standards Institute ANSI INCITS 284-1997 standard titled Identification Card ... Formulary and Utilization Management (UM) Requirements 81 110 - Reserved 83 120 - Marketing and Sales Oversight and Responsibilities 83 120.1 - Compliance with State Licensure and...
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Báo cáo khoa học: "Combining Source and Target Language Information for Name Tagging of Machine Translation Output" ppt
... previous token F4 and F5 are used to help resolve the type conflicts, and F6 and F7 to resolve boundary conflicts When there is a conflict, we need the confidence information from both ET and English ... and William J 2005 HMM Word and Phrase Alignment for Statistical Machine Translation Proc Human Language Technology Conference and Empirical Methods in Natural Language Processing Fei Huang and ... which addresses some of the tag conflict situations and gets additional gains Results from English NER and ET First, we analyzed the English NER and ET output to see the named entity distribution...
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fragment based drug discovery and x-ray crystallography
... Davies and Ian J Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening 61 Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey, and Roderick E Hubbard Combining NMR and ... Potent and Selective BACE-1 Inhibitors Daniel F Wyss, Yu-Sen Wang, Hugh L Eaton, Corey Strickland, Johannes H Voigt, Zhaoning Zhu, and Andrew W Stamford 83 Combining Biophysical Screening and X-Ray ... Marsh, Sandra Greive, and Marko Hyvonen Fragment Screening and HIV Therapeutics 181 Joseph D Bauman, Disha Patel, and Eddy Arnold Fragment-Based Approaches and Computer-Aided...
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báo cáo hóa học: " Simultaneous buried object detection and imaging technique utilizing fuzzy weighted background calculation and target energy moments on ground penetrating radar data" potx
... Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, USA (13-17 April 2009) DJ Daniels, P Curtis, O Lockwood, Classification of landmines ... Development of dual sensor hand-held detector, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets, Orlando, ABD, (5-9 April 2010) M ... 25 26 using GPR B-scan data, in SPIE Defense and Security Symposium, Detection and Remediation Technologies for Mines and Mine like Targets IX Orlando (2004), 905–912 TG Savelyev, LV Kampen,...
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Báo cáo hóa học: " Target estimation algorithm design using quantity data and target feature" pptx
... multiple-model estimator and neural algorithm for radar system Int J Innov Comput Inform Control 31(2):4809–4817 (2009) B Sugandi, H Kim, JK Tan, S Ishikawa, Real time tracking and identification of ... processing is adopted to identify the target feature And then the computation algorithm will calculate the similarity between the image of measurement and image of existing targets The process of main ... main works for conducting image processing is shown in Figure 1, and the descriptions are given as follows (1) Gray transformation and spatial filtering: In order to effectively determine the attribute...
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DRUG DISCOVERY AND DEVELOPMENT – PRESENT AND FUTURE pptx
... drugs and nanoparticles to tumors and sites of inflammation It is our hope that the readers find the book informative and that it stimulates new and innovative ideas to apply to drug discovery and ... and efficient means of bringing safe and effective products to the market Success along the development path hinges on using appropriate and robust models and biomarkers, which are relevant and ... improving the predictivity of efficacy and toxicity, which in turn depends on innovations and having reliable and robust biomarkers and using appropriate tools and methodologies References [1] Azmi...
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Báo cáo khoa học: "SemiFDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma" potx
... (66.7%) cases and disease-free and overall survival (DFS and OS) rates were 66.7% and 77.8% respectively Acute and late toxicity higher than grade (RTOG/EORTC) was observed in 7/27 (25.9%) and 1/27 ... study and drafted the manuscript MEM, LT, CB and LD were involved in data collection and review EM, BC and MC worked on analysis of data EI and MB participated in the design of the study and contributed ... was given by cisplatin and 5-fluorouracil in 15 cases and mytomicin and 5-fluorouracil in cases Statistical analysis PET-GTV and PET-CTV were respectively compared to CT-GTV and CT-CTV by Wilcoxon...
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Báo cáo y học: " Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohort" ppt
... one NRTI and at least one PI and at least one NNRTI, 3) an abacavir- or tenofovir-containing regimen with at least NRTIs, 4) a regimen containing ritonavir and saquinavir and one NRTI, and no NNRTIs ... contributions to conception and design, acquisition of data, and analysis and interpretation of data; 2) have been involved in drafting the manuscript; and 3) have read and given approval of the ... recruited in 1987–1991, and 1350 recruited in 2001–03 in Baltimore, Chicago, Los Angeles, and Pittsburgh The WIHS is also a multicenter study, with 2,623 women recruited in 1994–95 and 1,143 recruited...
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