design development and synthesis of novel cephalosporin group of antibiotics
Design, development and study of optimal parameters of a micro wire electrical discharge machining (WEDM) device
... 6.12 WEDM Surface and Surface profile at Ton of 12 and Toff of 36 µs 110 WEDM Surface and Surface profile at Ton = 30 and Toff = 36 µs 111 Example of buildup of recast layer and HAZ on workpiece ... 3: DESIGN AND DEVELOPMENT 36 3.1 Introduction 36 3.2 Development of the micro WEDM Device 36 3.2.1 Identification of the need 36 3.2.2 Design considerations 37 3.2.3 Computer Aided Drawings of ... development is presented Parameter study and machining characteristics are also reported Chapter describes the design and development of the WEDM device The factors considered in the design of...
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Design and synthesis of novel metal complex protein conjugation agents for applications in bio imaging
... diacetate (10) 40 4.7 Synthesis of Folate-NHS (11) 41 4.8 Synthesis of Folate-DOTA (13) 42 4.9 Synthesis of Folate-DO3tBu (12) 43 4.10 Synthesis of Mannich Salt (14) 46 4.11 Synthesis of Bis-disulfide ... source of image contrast, and offers the opportunity for an improved understanding of integrative biology, earlier detection and characterization of diseases, and facilitates a better evaluation of ... Bis-disulfide (15) 47 4.12 Synthesis of Bis-sulfone (16) 48 4.13 Synthesis of Bromoethyl-bis-sulfide (18) 50 4.14 Synthesis of Piperazine-bis-sulfide (23) 52 4.15 Synthesis of Tert-butyl 4-(2-aminoethyl)...
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Design and Synthesis of Novel Benzodiazepines
... Design and Synthesis of Novel Benzodiazepines Stephanie Lee MacQuarrie ABSTRACT Bivalent drug design is an efficient strategy for increasing potency and selectivity of many drugs ... Ellman’s synthesis of 1,4-benzodiazepines[31] 13 Scheme 1.9 Ellman’s synthesis of BZDs using Stille coupling[31] 14 Scheme 3.1 Synthesis of linker 56 Scheme 3.2 Synthesis of diazepam ... channel 2.3 Agonist and modulators of the GABAAR It is possible to group GABA receptor ligands according to their structure and function Two important classes of ligands are agonist and agonistic modulators,...
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DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC INSTRUMENTATION A Practical Perspective of the Design, Construction, and Test of Medical Devices docx
... DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC INSTRUMENTATION DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC INSTRUMENTATION A Practical Perspective of the Design, Construction, and Test of Medical ... issue of safety in the development of electronic medical devices, bypassing the difficult math and providing lots of insider advice In Chapter we present the development of amplifiers designed ... responsibility for the use of these circuits and/ or software or of systems incorporating these circuits and/ or software lies with the reader, who must apply for any and all approvals and certifications...
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Báo cáo khoa học: Kinetic studies on endo-b-galactosidase by a novel colorimetric assay and synthesis of N -acetyllactosamine-repeating oligosaccharide b-glycosides using its transglycosylation activity pptx
... and keratan sulfate (B) Arrows show the cleavage site of the glycosidic linkages of each substrate linkages of blood group A and B antigens, Gala1-4Galb14GlcNAc and GlcNAca1-4Galb1-4GalNAc, and ... concentrated, and lyophilized to produce (5.5 mg) and (7.2 mg) in 5.2 and 6.8% yields based on the acceptor added, respectively 1H- and 13C-NMR data of and are summarized in Table Preparation of GlcNAcb1-3Galb1-4GlcNAcb-pNP ... analysis of the reaction mixture obtained by endo-bgalactosidase-mediated transglycosylation and time courses of the production of transglycosylation products and 10 from and degradation of (A)...
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báo cáo hóa học: "Initial development and testing of a novel foam-based pressure sensor for wearable sensing" doc
... courtesy of the University of Bath, England, showed that the stress-strain profile of the unadulterated PU foam sample and that of the PPy-coated PU foams sample were similar showing regions of elastic ... durable and washable over an indefinite period of time In a garment-integrated context, washability of components is important to the preservation of normal user patterns of care and maintenance of ... variety of body shapes and sizes would be hard to predict Similar issues would arise with sizing, fit, and sensor locations on the foot Because of the increased number of sensors and precision of...
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identification, design and synthesis of oxygenated hydrocarbon-based carbon dioxide-soluble polymers for chemical and petroleum engineering applications
... self-interactions, and multidentate interaction between CO2 and solute functional groups v TABLE OF CONTENTS TABLE OF CONTENTS VI LIST OF TABLES X LIST OF FIGURES ... falling distance of 0.05 m 159 xi LIST OF FIGURES Figure 1.1 Phase behavior of supercritical CO2 and H2O Figure 1.2 Viscosity of CO2 as a function of temperature and pressure ... the thickener in CO2, and associative groups (usually being CO2phobic, e.g styrene) which can improve CO2 solution viscosity Of these two segments, design and synthesis of CO2-philic polymers...
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Design and synthesis of stimuli responsive polymer based nanoparticles
... Photographs of PBS solutions of Fe3O4-g-G4-mannose MNPs (a) before and (b) after addition of 0.1 µM of ConA in the presence of a permanent magnet (c) Schematic illustration of the binding and aggregation ... KVDA3 and (4) KVDA4 of Table 3.1 at (a) pH and (b) pH The concentration of each copolymer solution was 0.1 wt% Figure 3.8 TEM images of the self-assembled vesicles of the KVDA3 copolymer of Table ... (Dh) of the cross-linked hybrid hollow nanospheres prepared from KVDM1 copolymer of Table 3.2 and their size distribution in aqueous media of 25 oC and 40 oC at pH 7, and (b) the effect of temperature...
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Design and synthesis of functional graphene composites and their applications
... of PNP+GO-, GO and PNPB solutions at laser pulses of 532(c and e) and 1064 nm (d and f), where c) and d) show intensity-dependent scattering signals at 532 and 1064 nm, respectively, and e) and ... formation of bond between the free radicals of organic molecule and C=C 6|Page Chapter 1: Introduction bond of graphene and (b) formation of bond between organic functional groups and oxygenated-groups ... DESIGN AND SYNTHESIS OF FUNCTIONAL GRAPHENE COMPOSITES AND THEIR APPLICATIONS JANARDHAN BALAPANURU M.Sc., University of Pune, India A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY...
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Design, optimization and applications of novel electrochemical sensors based on prussian blue
... dependences of Epc towards (a) the logarithm of K+ concentration in (i) absence of Na+ with slope of ca 60 mV (ii) presence of 50 mM Na+ with slope of ca 120 mV; and (b) the logarithm of Na+ concentration ... crosssectional views of (a) a PB-PGE based on the design of encasing the pencil lead with an insulating layer and (b) a PB-PGE based on the design of direct immersion of a fixed length of the pencil ... voltammograms of the PB-ME showing the response of Epc1 (brown) and Epc2 (green) towards increasing concentrations of (a) K+ and (b) Na+ Graphs showing the dependences of (c) Epc1 and (d) Epc2...
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Design and synthesis of donor acceptor hybridized small molecules and graphene derivatives for photovoltaic and optical studies
... pyrazines and thiadiazoles, in addition cyano and nitro groups also reduced band gap when they are attached to conjugated units Using combinations of these donor and acceptor groups, a variety of low ... semiconductor and the basic working principle of organic solar cell will be discussed In the next three chapter of this thesis, the design, synthesis and photovoltaic device testing of new photoactive ... delocalization of these states along the conjugated backbone creates two continuous bands of filled, and empty, states (Figure 1.2) The energy gap between the top level of the filled (i.e HOMO) band and...
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Development and implementation of efficient segmentation algorithm for the design of antennas and arrays
... gives the best performance with an impedance bandwidth of 68.3%, a dB gain bandwidth of 45.5% and a broadside gain of 7.07 dBi at 5.4 GHz viii List of Figures FIG 2.1: AN ARBITRARY SHAPED SCATTERER ... 69 FIG 3.8: PHOTOGRAPH OF THE FABRICATED CHEBYSHEV BANDPASS FILTER 71 FIG.3.9: CHEBYSHEV BANDPASS FILTER (A) LAYOUT OF THE BANDPASS FILTER (B) SMALL DOMAIN OF THE BANDPASS FILTER L=22.45, ... applications and this could save a lot of space in product design [3] Antennas should be relatively cheap and easy to manufacture They should be lightweight, low-profile and robust One type of antenna...
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Development and evaluation of a novel nanoparticulate delivery system of arsenic sulfides
... suspension with particle size of 100 and 150 nm and induction of apoptosis Ye HQ et al., College of Life Science and Technology, Huazhong University of Science and Technology, PRC Myeloid leukemia ... JZ and Ho PC, 2006] Inhibition of growth and promotion of apoptosis Observations of the clinical utility of realgar in the treatment of APL have triggered investigations into the mechanisms of ... pathway by up-regulation of surface expression of TRAIL and TRAIL receptors and activation of BID in cells expressing mutant p53 [Akay C et al., 2004] Induction of the release of mitochondrial AIF...
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Design and synthesis of cysmethynil and analogues as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)
... .57 3.4.2 Synthesis of Series and compounds .58 3.4.3 Synthesis of Series compounds 63 3.4.4 Synthesis of Series compounds (4-1 and 4-3) 67 3.4.5 Synthesis of Series compounds ... LIST OF SCHEMES Scheme 3-1 Synthesis of Series and compounds 48 Scheme 3-2 Synthesis of Series compounds 52 Scheme 3-3 Synthesis of Series compounds 52 Scheme 3-4 Synthesis of ... QSAR of indoloacetamides 160 Appendix Synthesis and Characterization of Cysmethynil Analogues by Dr Suresh Kumar Gorla 163 A2.1 Synthesis of 1-8 (Series 1) 163 A2.2 Synthesis of...
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Development and application of novel capillary electrophoresis techniques for analysis of DNA fragments and organic pollutants
... Department of Chemistry, Ms Gek Luan Loy in Department of Biological Science and Ms Agnes Lim in Department of Material Science I would like to thank all of my colleagues in Prof Li’ group, who ... Electrophoresis of ΦX174 DNA under Different Applied Voltage 66 XX List of Figures Figure 2.8 Demonstration of Separation of ΦX174 DNA by CE-PGD and CE-UV 67 Figure 3.1 Design of CCD ... Instrumentation and Modes Since the introduction of commercial CE instrumentation from late 1988, the speed of development and application of this technique was enhanced Requirement of only simple...
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Development and applications of novel solvent minimized techniques in the determination of chemical warfare agents and their degradation products
... had the privilege of working under the expert guidance of Prof Lee Hian Kee and Dr Chanbasha Basheer of the Department of Chemistry at the National University of Singapore and would like to thank ... contains analytical proof of the presence of chemicals reported and provides high certainty of the absence of other chemicals relevant for the implementation of the CWC and does not contain information ... in any proficiency test Since 1996 to 2007, a total of twenty two official OPCW proficiency tests have been conducted As of the 23rd Official OPCW Proficiency Test, there are twenty designated...
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Development and applications of novel liquid phase microextraction techniques
... 1.1 Historical Development of Microextraction Techniques 1.2 Principles and Applications of SME and Membrane-Based LPME Techniques 1.3 Hyphenation and Automation 15 1.4 Comparison of SME, Membrane-Based ... Materials and Chemicals 87 4.1.2.2 GC/MS Analysis 88 4.1.3 Results and Discussion 93 4.1.3.1 Procedure of HFP-LPME 93 4.1.3.2 HFP-LPME of Pesticides and PAHs 97 4.1.3.3 Evaluation and Recoveries of ... recoveries and precision of HFP-LPME Table 4-3 Recoveries, precision, linearity and LODs for water and urine samples Table 5-1 The effect of various concentrations of the donor phase and the acceptor...
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Knowledge discovery in biomedical research and drug design the development and application of biological databases
... areas of biomedical science The relevant technologies of database development and knowledge discovery are discussed as well 1.2 Development and Categories of Biological Databases 1.2.1 History of ... way, which offers a platform for further analysis and knowledge discovery from these data Development and application of biological databases have pushed and accelerated the development of Bioinformatics ... academic and company scientists And because of the efforts of these scientists and funding agencies such as NIH in USA and EMBL in Europe, Bioinformatics became more and more prominent and diverse...
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Design, fabrication, and characterization of a solenoidsystem to generate magnetic field for an ECR proton source
... is capable of producing off-resonance, mirror, and flat magnetic field configurations A mirror ratio of 1·1 and a maximum flat field of 1400 G has been obtained The measured values and the design values ... varying the size of the solenoid coils, thickness of iron jacket, and amp-turns (NI) The optimum values of NI for the side and middle solenoid coils were obtained to be 12950 and 8250 respectively ... Make:Megger, Biddle, England) Magnetic field mapping The performance of an electromagnet gets influenced by the design and material limitations, errors in construction, and the stability of the power supply...
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Tài liệu Study on the Development and Marketing of Non-Market Forest Products and Services ppt
... hydrological cycle Regulation and redistribution of surface and below-ground run off Increasing of the total annual river run off Flood protection Maintenance of arable land Wind and shoreline erosion ... 8.4: Area of forests important for the provision of different groups of forest goods and services 26 | P a g e Study on the Development and Marketing of Non-Market Forest Products and Services ... Siltation prevention Maintenance of productivity on arable land Maintenance of natural productive soils Maintenance of soil vitality and ecosystem productivity Land and landscape conservation Flood...
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