... to the summit ofthe wall Hence the contrast between the shadows ofthe peaks ofthe western wall on the floor at sunrise, andofthe same peaks on the region west ofthe border at sunset is very ... Somewhat less than half of what we see of it consists of comparatively level dark tracts, some of them very many thousands of square miles in extent, the monotony of whose dusky superficies is often ... following some particular line of research, is shown by the great success in recent years of societies, such as the British Astronomical Association withits several branches, the Astronomical Society...
... expression and purification was carried out using the GST expression system The GST expression system is based on the inducible, high level expression of genes/fragments of genes as fusions of GST ... mediating the switch between these two modes in response to the presence of various attractants/ repellents in the medium The chemotaxis system consists of a system of sensory receptors in conjunction ... were named as dgc1-3 and pde 1-3 They studied the activities of DGC and PDE from the cellular extracts of mutants and confirmed the association of these genes with products possessing the above...
... applicants address the potential ethical issues of their proposals, both in the proposed methodology andthe possible implications oftheresultsThe specific requirements for addressing ethical issues13 ... this call topic, neglected parasitic diseases include the kinetoplastid diseases (sleeping sickness, leishmaniasis, Chagas disease) and helminth diseases [lymphatic filariasis, onchocerciasis, schistosomiasis ... (borreliosis and other tick-borne bacterial diseases), protozoan (babesiosis, giardiasis), and/ or helminthic (trichinellosis, taeniasis and human echinococcosis) human diseases Proposals must provide...
... (F and inter- (F popu) IS ) ST lation components Estimates ofthe Fstatistics were made according to the method of Weir and Cockerham (1984) They were weighted by the stand sample size andits ... to associations The originality of Croatian beechwood associations is mostly related to the existence of rather dry stands This ecological character has induced the settlement of a special association, ... stands seems to be higher in the south where ecological conditions are more heterogeneous, the stands are older and their sources more numerous (Comps et al, 1989) Our purpose was to examine the...
... and his drama consists almost entirely ofthe speeches ofthe accused, witnesses, prosecutors, defence attorneys and judges There are almost no stage directions, and Weiss provides only a short ... liberal account, which considers Jews individuals and not different from other peoples, does not recognise the exigencies of power, and in this sense the fascist perspective on the Jews is just as true ... committed in its name and how to deal withthe pressing issues of guilt, responsibility and expiation But they were also confronted with a series of practical and theoretical issues arising from the Holocaust...
... became less discoloured, andthe hardness about his stomach seemed to yield; but the ascites and anasarcous symptoms increased so as to oppress his breathing exceedingly Alkaline salts, and other ... from the cases I now present to him These cases must be considered as the most hopeless and deplorable that exist; for physicians are seldom consulted in chronic diseases, till the usual remedies ... distressing sense of tightness across his stomach, his urine was little, and high coloured, and his legs began to swell; his pulse slender and feeble From the 20th of September I frequently saw...
... studies to support the policy rationale and types and quantifications ofthe costs and benefits f The sources relied upon in determining and calculating the costs and benefits 3) The Notice of ... non-compliance penalties; v Performance standards rather than design standards Performance standards express requirements in terms of desired outcomes Design standards express requirements in ... description ofthe agency s methodology used in making the above determinations b Evaluation of Costs and Benefits The agency shall provide a comprehensive enumeration ofthe costs and benefits of the...
... complex, rapid dissociation was observed, reaching the basal levels of resonance units (GlnK free surface) within seconds To test the effects of various molecules on the interaction of TnrA with GlnK, ... truncations Fig S3 Crosslinking analysis of truncated TnrA proteins Doc S1 Purification of His6-tagged TnrA proteins, purification of GlnK-ST and GS-ST, and glutaraldehyde crosslinking assays This supplementary ... according to the three sequential binding sites model BIAcore analysis ofthe GS–TnrA interaction Theresultsofthe immunoprecipitation experiments revealed a constitutively present GS–TnrA complex...
... loading ofthe gel and integrity ofthe RNA (lower panel) The positions ofthe 2 8S and 1 8S rRNAs are indicated on the left be responsible for constitutive stabilization ofthe MARCKS mRNA Discussion ... pBS-DC5 and pBS-MARCKS-52nt) are schematically presented (sequence according to [38]) These constructs were used to synthesize truncated RNA segments ofthe MARCKS 3¢-UTR The 3¢ termini of pBS-DC4 ... Ó FEBS 2003 Fig Formation of two major complexes between Swiss 3T3 proteins andthe 3¢-UTR ofthe MARCKS mRNA (A) The MARCKS 3¢-UTR, the stop codon UAA ofthe coding sequence (CDS) andthe poly(A)...
... transformed withthe combination of plasmids shown The growth of single yeast colonies containing these plasmids are shown in (B) and (E) on SD plus L-histidine and adenine and (C) and (F) on SD ... transformed withthe combination of plasmids shown The growth of single yeast colonies containing these plasmids are shown in (B) and (E) on SD lacking L-histidine and adenine and (C) on SD plus ... selected andthe production of macroscopic colonies in soft agar assessed Theresults show that transformation is suppressed by 50% in cells containing Evi1D706–707 and UXT (Fig 6C) The empty...
... abolished its interaction with eIF4E, and this correlated with a defect in infectivity in Brassica perviridis [11] The simplest hypothesis is that VPg recruits eIF4E to initiate the translation of ... the complex formation using the cap analogue m7GDP There are considerable discrepancies between the affinities ofthe cap analogue published so far In the absence of VPg, the value ofthe dissociation ... ([V]free) is assumed to be close to [V]total The same saturation behaviour was observed as for lower concentrations of VPg (Fig 3A) In the case of strict competition, the Fig (A) Binding isotherms of...
... leads to accumulation ofthe pre-rRNAs 3 5S, 2 7S and 7S [13–16] The exosome is also involved in processing of snoRNAs and degradation of defective rRNAs and cytoplasmic mRNAs [17,18] These results ... interact withthe proteins in the pre-6 0S complex, but is less concentrated in the nucleolus These results raised the question of whether any ofthe truncated mutants of Nop53p, when under control of ... does not degrade RNA by itself, its presence stimulates the RNase activity ofthe exosome It is possible that the stimulation ofthe exosome activity is due to recruitment ofthe complex to the...
... much they use the prosthesis and in the type of activities they can perform with their prosthesis [7] Procedure of translation The procedure of cross-cultural adaptation ofthe English version of ... supervision) and (yes, independently) The total LCI score is the sum ofthe item scores and can range from (worst) to 42 (best) Similarly, subscale scores for basic and advanced capabilities withthe ... lowest possible score [21,23] Statistical analysis The LCI scores (total, basic and advanced) were calculated and presented as means, medians and standard deviations All statistical tests were...
... overall summary scores (PCS and MCS) are obtained from the SF-36 Norm-based scoring algorithms were used for the scales and for the PCS and MCS scores, which are normed to a mean of 50 and standard ... to severe plaque psoriasis (Table 1) Assessing the burden of psoriasis on health-related quality of life SF-36 summary scores Based on the 2002 MEPS data, baseline PCS scores for patients in the ... psoriasis SF-36 scale score norms for men and women 45 to 54 years of age from the NSFHS were compared with SF-36 scale scores by treatment group at Week 16 [24] To compare PCS and MCS scores...
... operation, andthe patient died months after the operation Discussion Since Posen et al reported the first case of an UC with OGCs ofthe pancreas associated with a mucussecreting cystadenocarcinoma ... neoplasms ofthe pancreas, in which an ovarian-type stroma is a histological requirement for the diagnosis of a MCN [13] Based on these findings, this case was diagnosed as an UC with OGCs originating ... rarely combined with MCNs Since the first description of UC with OGCs by Rosai, the origin ofthe tumor has been controversial In our case, OGCs were positive for the histiocytic marker CD68 and...
... predict the biological behaviour of these neoplasms [30-35] Among them the Weiss system has the most important position and is widely used This system supports that the presence of four or more ofthe ... Histological classification of adrenocortical oncocytic tumours has been so far a matter of debate There is no officially established histological scoring system regarding these rare neoplasms and therefore ... past years Some authors have suggested that these markers could be used as potential indicators ofthe benign or malignant nature of ACs [37-39] Bisceglia et al results concerning Ki-67 expression...
... responsibility for the manuscript, and reviewed the draft extensively DK was the assistant surgeon and composed the first drafts ofthe manuscript PA performed the histological examination ofthe ... breast has an excellent prognosis, as the incidence of lymph node metastasis is lower and distant metastases uncommon [1] Even rarer are the cases of ACC intermingled with other types of breast cancer ... Discussion ACC ofthe breast is a rare histopathologic type of slow progression and represents only 0.1% of breast cancer cases In sharp contrast to the extra-mammary counterpart, ACC ofthe breast...
... transaminase levels had a strong inverse correlation with our patient s consciousness These results strongly suggest that the pathogenesis of coma in classic hepatic encephalopathy differs from ... liver biopsy Again, this is compatible with our finding of numerous hepatocytes with signs of ballooning (Figure 1), which is a hallmark of oxidative stress andof hepatocyte apoptosis and autophagy ... elevated transaminases, whereas liver steatosis was diagnosed in ultrasound imaging, as was found in our patient In addition, these authors detected increased markers of oxidative stress in the liver...
... capecitabine and gemcitabine therapy and had stable disease as assessed by CT scans However, in early 2003 she was found to have declining renal function and was forced to stop chemotherapy She was observed ... mitoses The amount of fibrosis present can be variable and psammoma bodies can also be found [4,8] Areas of invasion are typically not seen [4,5,8] Microscopic analysis of cytology from ascites ... months later, and still had gross disease visible in the peritoneum Post-operatively she received three additional cycles of intraperitoneal cisplatin and intravenous sodium thiosulfate She subsequently...
... increases to as high as 1% with assisted reproductive techniques [1] This is because of transfer of embryos by ART techniques into affected tubes and peristaltic movements not expel these embryos The ... clinical symptoms Reece et al [1] defined abdominal pain, adnexal mass, peritoneal irritation and an enlarged uterus as signs and symptoms suspicious of HP Transvaginal ultrasound and assessment ofthe ... department with symptoms of a rupture of ectopic component Thus, a preoperative diagnosis of HP is still a challenge Serial b-HCG levels are not of much significance in the diagnosis of HP as subnormal...