90 s dawn of the human web
Báo cáo Y học: S-Decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1) ppt
... allocrites or inhibitors, as described in the legends Substrates and inhibitors were added to the reaction mixtures or inorganic phosphate standards prior to the addition of ATP The transfer of the ... with the reconstituted MRP1, isolated from insect cells [37] or human tumour cells [38] The similarity of the basal ATPase activities of the two isolated domains does not seem to correlate to the ... encouraged us to measure the effects of MRP-specific allocrites on the ATPase activity of the isolated NBDs We have tested several MRP-specific allocrites in their ability to stimulate the ATPase activity...
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Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
... knowledge of whether the samples were control or experimental The total number of basal and suprabasal epithelial cells along the six microscopic fields and the number of basal and suprabasal cells stained ... [5] The possible malignant transformation of OLP is a subject of controversial discussion in the literature While some studies support a premalignant nature of OLP [6,7], others argue against the ... diagnostic errors, the inclusion of cases that had a known history of exposure to recognized carcinogens, and the report of cases of lichenoid dysplasia as malignant transformation of lichen planus...
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Contrastive analysis on english and vietnames proverbs referring to parts of the human body
... human body VI Design of the study Part A Introduction Rationale for choosing the subject Aims of the study Objects of the study Methods of the study Scope of the study Design of the study Part B ... form) The classification of parts of the human body according to the position In the system of the proverbs, the system of words referring to parts of the human body is divided into details according ... process The proverbs referring to parts of the human body contribute to expression of peoples thoughts, feelings etc Parts of the human body The parts of the human body used in proverbs are diversified...
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The transference of meaning through class of words denoting parts of the human body in english and vietnames
... Analytical result of the definitions in dictionary of these words allows us to define 17 forms of the types of semantic transference that are used in this class of words ( this classification is based ... Objectives of the study Methods of the study Design of the study Part B Contents Chapter Theoretical preliminaries Chapter The contrastive analysis of class of words denoting parts of human body ... have the tables sum up the percentage of the forms of each types of semantic transference and the percentage of the types of semantic transference used in these classes Table 2: The percentage of...
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Tài liệu Overview of the XML web Services intracstructure pptx
... find the Web Service solution in a separate location called SecurityWebServices on the Web site The Chapter 13 solution will contain the sample forms that are created to call methods from the Web ... Chapter 13 solution will contain the sample forms that are created to call methods from the Web Service ...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... ligands for enzymes in the human nucleotide metabolism These were selected as substrates, intermediates and products of other enzymes in the human nucleotide metabolism The library was screened ... measurements based on four time samples using the DE-81 (DEAE-cellulose) filter paper assay adopted from the deoxynucleoside kinase assay method [44] with tritium-labeled bases as substrates The ... phosphoribosyltransferase where the conformation is also stabilized by crystal contacts [24] The bound phosphate ion superposes well with one of the phosphates of pyrophosphate in the transition state analog...
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Tài liệu Metropolitan Community College’s Administration of the Title IV Programs doc
... COMPASS, COMPASS English as a Second Language (ESL), ASSET, and “Combined English Language Skills Assessment” (CELSA).4 The COMPASS ESL and CELSA tests were used only for ESL students The CELSA ... under this subpart of (1) The test taken by the student; (2) The date of the test; and (3) The student 's scores as reported by the test publisher, assessment center, or State Students Ineligible ... 16 students, the assessment center manually scored the tests For five of those eight students, the assessment center did not ensure that the tests were administered by certified test administrators...
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Tài liệu AUDIT OF THE DEPARTMENT OF JUSTICE’S IMPLEMENTATION OF THE INTEGRATED WIRELESS NETWORK ppt
... required the USMS to ask permission each day the USMS needed to use the system Ultimately, the FBI disabled five USMS radios because it said there was too much traffic The USMS Chief Inspector for the ... status of these components' LMRs follows 19 For purposes of this audit, obsolete systems are systems that are no longer supported by the manufacturer or the manufacturer is unable to supply spare ... that they can be received by the other systems This allows the agencies to continue using their existing systems but requires twice as much spectrum because each system occupies separate channels...
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Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc
... mutagenesis across the HsRad51-L1 loop and measured the fluorescence changes of the tryptophan residues upon DNA binding Results Strategy of mutational analysis In order to study the functions of the ... salt-induced ATPase activity very similar to that of HsRad51 in the absence of DNA (Figs 2D,E) These results suggest that the Tyr232 residue is within neither the subunit–subunit interface nor the ATP-binding ... Trp, can stack with the base moieties of ssDNA for the interaction Such contacts have been observed in the interactions of the SSB and RPA proteins with ssDNA [23,24] The Rad51-Tyr232 side chain...
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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt
... initiation sites at +1 Black arrowheads show the transcription initiation sites of the human and a white arrowhead shows the transcription initiation site of the mouse Dashes show gaps and asterisks show ... promoter use seems to be conserved in the mouse KLK11 gene Mouse brain expresses only isoform mRNA, whereas mouse prostate expresses both isoforms and [9] The transcription initiation sites on human ... KLK11 isoforms is conserved in mouse tissues [9] Interestingly, prostate cancer cells express only isoform 1, whereas tissue from normal prostate and benign prostate hypertrophy express both isoforms...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... [21,23] Such an increase in the number of TFs is associated with higher control of gene regulation [24] Interestingly, such an increase is based on the use of the same structural types of proteins Human ... complexes Thus, the final effect of one of these complexes is determined by its TF composition The number of TFs varies among organisms, although it appears to be linked to the organism s complexity ... it is connected with the presence of modular organization (see below) Because hubs are linked to many other elements but tend not to link themselves, disassortativeness allows large parts of the...
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Tài liệu Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity docx
... to those disease processes in human subjects is currently unknown but in view of the extensive differences between the TP isoforms in terms of their mechanisms of signaling [18,19], modes of regulation ... underlined sequence corresponds to the Mlu1 cloning site) in combination with specific sense primers designed to amplify progressively shorter regions of Prm3 The following lists the identities of the ... luciferase assays as described above HEK293 and HEL cell supernatants were assayed for both firefly and renilla luciferase activity using the Dual Luciferase Assay SystemTM, essentially as previously...
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Tài liệu Commodore Barney''''s Young Spies A Boy''''s Story of the Burning of the City of Washington docx
... instant the canoe glided into the obscurity of the shadows cast by the overhanging trees With the disappearance of Darius there came upon me the full sense of my responsibility, for I was the ... Yankees, an' the other is sneakin' in some corner!" There came the sound of hurried footsteps, and then the light of the lantern so far illumined the head of the stairway that I could see Darius, ... it as tough as is deserved These others are prisoners of war; but you two are traitors and spies, therefore must expect to fare according to your deserts." "That 's about the size of it, Amos,"...
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Báo cáo khoa học: Novel repressor of the human FMR1 gene ) identification ¨ of p56 human (GCC)n-binding protein as a Kruppel-like transcription factor ZF5 ppt
... promoter regions of human genes revealed the presence of ZF5 consensus sites within approximately 60% of human gene core promoters [31] In spite of significant over-representation of these sites in promoter ... Germany) The mass spectrometer was operated in the reflector mode using previously described settings [39] Mass spectra were calibrated using known masses of internal standards [40] Peptide peak lists ... Southwestern assay The results of the MALDI-TOF analysis indicated that one of these, p56, is a Kruppel-like transcription factor ZF5 Although all ¨ ZF5-binding sites found previously by CAST assay are...
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Báo cáo khoa học: Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin potx
... successive chromatography steps on Sepharose 6B and 2B The supernatants of the hybridomas were screened, and the clones were selected by their strong reaction against the gastric surface epithelium ... against mucin is used, whether it shows cross-reactivity towards other mucins Among the gel-forming mucins, the MUC5AC C-terminus shows the highest similarities with the MUC2 C-terminus To analyze ... to direct the protein synthesis into the secretory pathway L31 [21], the cDNA clone used in previous studies aimed at mapping the epitopes of the mAbs against M1 to the C-terminal part of MUC5AC...
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Báo cáo khoa học: The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin pot
... was YPD without the yeast nitrogen base S cerevisiae cells were grown at 28 °C unless otherwise stated To analyse the response to different media and sensitivity to various compounds, S cerevisiae ... Immunochemicals, Inc., Gilbertsville, PA, USA) followed by analysis of the immunoblots with the Li-Cor Odyssey system Ppp4 antibodies were raised against the N-terminal 57 amino acids of human Ppp4 as described ... tag, respectively) elutes from Superose at the same anomalous position of 450 kDa as Drosophila His6–R2 (Fig 3) and human His6–R2 [16] Examination of the phenotype of S cerevisiae strains carrying...
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Báo cáo khoa học: Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor jB1 and mitogen-activated protein kinase pathways doc
... primers specific for the human isoforms There was evidence for the expression of mRNA for the P2Y receptor subtypes P2Y2, P2Y6, P2Y11 and P2Y13 and for the P2X4 receptor, whereas expression of the ... translocation of the transcription factors NF-jB1 (p50) and RelA (p65) was also involved These pathways lead to a massive arrest of the cells in the S phase Activation of NF-jB by P2Y receptors ... added to the class of the critical regulators of cell cycle progression, so far consisting of hormones, growth factors, and cytokines Further detailed investigations are needed to unravel the subtype...
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Báo cáo khoa học: The protein shuffle Sequential interactions among components of the human nucleotide excision repair pathway pdf
... binding to these lesions [15] This hypothesis was supported by the results of an NMR structural study of DNA decamers that was designed to elucidate the influence of mismatched bases on the DNA structures ... FEBS 1603 The protein shuffle in NER pathway C.-J Park & B. -S Choi the Ssl1 subunit of yeast TFIIH are responsible for the observed Ub ligase activity [23] (Ssl is a homolog of the p44 subunit of ... nucleases As is the case with other members of the FEN-1 family, XPG has two highly conserved nuclease motifs known as the N- and I regions [38] Although these regions are separated by only a short...
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Báo cáo khoa học: Identification of NF1 as a silencer protein of the human adenine nucleotide translocase-2 gene pptx
... monitored using the DNase I assay As seen in Fig 2, proteins that protect Sites Fig Summary of the human ANT2 promoter region (A) Repressor elements in the Sp1 C box, the silencer region (Site-2/Site-3), ... to repression of the ANT promoter Deleting the Site-2/Site-3 silencer elements eliminates repression of the HSVtk promoter in transfected HeLa cells [14] To study the roles of Site-2 and Site-3 ... serum was used as a control for supershift experiments The major shifted complex is marked by an arrow Free probe is seen near the bottom of the gel Repression of the HSVtk promoter via the silencer...
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