3 quality control and quality issues in the staging of esophageal cancer
the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer
... phosphorylated and processed into p52 The processing of p100 to p52 results in the loss of the ankyrin repeats in the C-terminus and allows translocation of the RelB/p52 dimers into the nucleus ... Binding of the p65/p50 dimer results in IκBα resynthesis and IκBα is then exported back to the cytoplasm, binding NF-κB and inactivating the pathway Protein phosphatase 2A is a key regulator of ... been added with the division of the luminal subtype into luminal A and B, and the inclusion of the claudin-low subtype [50-51] Both the luminal A and B subtypes show expression of ER, PgR or ER...
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Tài liệu ISSUES IN THE INTEGRATION OF RESEARCH AND OPERATIONAL SATELLITE SYSTEMS FOR CLIMATE RESEARCH pdf
... from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine The members of the committee responsible for the report were chosen for their ... services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the National ... agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities The Council...
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Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx
... degenerate case of the NSI action In the case of the NSI action, the speaker and hearer mutually know of a plan that will result in identification of the intended referent, and in the case of the S[ action, ... along the horizontal axis of Figure There are really' two kinds of definite referring actions: one is that in which the precondition is mutual knowledge of a description and the other in which there ... possible There are several ways to measure the complexity of a description, including the number of descriptors involved and the ease with which these descriptors can be incorporated into the utterance...
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Postal Savings and the Provision of Financial Services: Policy Issues and Asian Experiences in the Use of the Postal Infrastructure for Savings Mobilization pdf
... Postal savings for the people The introduction of savings accounts at post offices followed the rise of the savings bank movement in Scotland and thrift movements elsewhere in the beginning of the ... of home Internet and telephone banking services in place of postal counter services in Finland and other countries invite further scrutiny Although Internet usage in Finland is 43 per cent, the ... network In 1987, in addition to the post offices, it had 50 branch offices in 33 cities and towns, 13 of them in the Helsinki area alone Following Finland’s commercial banking crisis in the early...
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Báo cáo y học: "Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia" ppt
... guide the choice of antibiotic therapy and confirm the diagnosis of VAP What is clear is that avoiding delay in sampling and initiating therapy quickly are more important than the type of quantitative ... ventilated patients, the clinical diagnosis was correct in 62% of cases and therapeutic treatment plan was appropriate in only 33% of cases Given the difficulty in diagnosing pneumonia in the ventilated ... pneumoniae infections; cystic fibrosis increases the risk of P aeruginosa and S aureus infections; and trauma and neurologic patients are at increased risk for S aureus infection [16,22] The time of...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... partitioning of the protein into an aggregated state The effect of copper binding on the secondary structure was determined using CD in the far UV To prepare proteins without Cu2+, part of each protein ... copper binding could still allow domain swapping to occur It is of interest that a N-terminally truncated prion protein, lacking the copper binding domain is capable of domain swapping and forms ... understanding what causes the loss of appropriate metal binding might be crucial for the understanding of the role of amyloidogenic proteins in a number of neurodegenerative disorders Copper binds...
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Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx
... application of SH2 domain binding peptides, which results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain For ... C-terminus Kinase domain and C-terminus SH3 domain and C-terminus SH2 domain and C-terminus SH3, SH2 domain and C-terminus N-terminal, SH3, SH2 domain and C-terminus N-terminal, SH3, SH2, kinase ... found in neurons n-Src contains a six amino acid insertion in the SH3 domain, and is only expressed in neurons [3] The SH3 and SH2 domains in Src have been recognized to be involved in the negative...
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AN ACCOUNT OF TIMBUCTOO AND HOUSA, TERRITORIES IN THE INTERIOR OF Africa docx
... and if no person of the royal line be the object of their choice, they may elect one of their own body The members of the council are appointed by the king; he chooses them for their wisdom and ... goods brought in by the gate of the Nile, (which is the gate of the Negroes,) pay a tax: another part of the revenue is two per cent, in kind on the produce of the land; but the people of Barbary ... made of the finest Tedla wool, which is equal to the Spanish, and is the produce of the province of that name, (for the situation of which see the map of the empire of Marocco, facing page 55.) The...
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... [21–25], and DGD° values in the presence of these osmolytes are given in Table However, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethylglycine have ... efficiency in the presence of this group of osmolytes Interestingly, there is a linear relationship between DDGD° and Dlog(kcat ⁄ Km) in the presence of methylamines and sugar However, the slopes of the ... (a) the main driving force for the folding is the unfavourable interaction between the osmolyte and the peptide backbone, and (b) the total contribution of side chains to the stability of the...
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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... ATP into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting ... 3A) and ATP (Fig 3B) in the absence and presence of curcumin, using the coupled enzyme assay In Fig 3A, the half-maximal activation of the ATPase by Ca2þ was measured in the absence of and in the ... within the ATP binding pocket of the nucleotide binding domain, also precluding ATP binding [15,43] Therefore if curcumin affects this conformationally induced fluorescence change, it must be binding...
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corporate social responsibility strategies for sustainable development for small and medium enterprises in the village of bac ninh province, vietnam
... represents a unique Kinh Bac region (Northern of Vietnam) The businesses in the village have been promoting their intellectual inheritance of the essence of his father left, forming the well-known ... contribution to the growth of local economy, the business types in the village of Bac Ninh is the team unity called "the small and medium enterprises in the village of Bac Ninh" Types include: Company, ... clarify the strength of the enterprise, the weaknesses of the business 21 The specific target for analysing of the inside and outside factorsin the enterprises from which we form strategic business...
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Surfing the waves of globalization - Asia and financial lobalization in the context of the trilemma
... kinh tế mức độ lạm phát trung hạn câu hỏi cho nhà phân tích kinh tế vĩ mô chuyên gia tài Bài nghiên cứu ‘’Surfing the Waves of Globalization: Asia and Financial Globalization in the Context of ... kinh tế tư nhân ( B ) kinh tế châu ( C) nến kinh tá châu mỹ la tinh ( d) khác Mặc dầu dự án tóm tắt bảng không khớp với thực tế cảu kinh tế tư nhân, tìm vài trường hợp khớp với lập bên Braxin ... hội nhập tài tiền tệ độc lập xu hướng đặc sắc minh chứng kinh nghiệm kinh tế euro Mặt khác, kinh tế thị trường xuất hội tụ theo hướng áp dụng với linh hoạt quản lý tỷ giá hối đoái, trì mức độ trung...
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Water pollution and habitat degradation in the Gulf of Thailand ppt
... Heavy metals in seawater and sediments of the eastern coast of the Inner Gulf of Thailand In: Proceedings the 5th Seminar on Research in Water Quality and Quality of Living Resources in Thai Waters, ... especially in the inner Gulf of Thailand It is evident that the increasingly deteriorating conditions in the marine environment of the inner Gulf of Thailand have threatened the existence of several ... 1984 Total mercury in bivalves of the east coast of the inner Gulf of Thailand In: Proceedings the 3rd Seminar on Research in Water Quality and Quality of Living Resources in Thai Waters, 26–28...
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Báo cáo khoa học: Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice doc
... extinction coefficient of the protein, and thus the increase in absorbance in the aromatic region Shortly thereafter, a gradual unfolding of the protein occurs that results in the increase of ... After the initial dilution caused by binding and retaining in the tissues, the blood level of these proteins stabilized within h, and then remained nearly unchanged for up to 24 h after injection ... constant, and the spectra were taken in several time intervals (indicated on the right) (D) FTIR spectrum of CD69 protein in the region of the amide I and II bands (the full line) The dash–dot line...
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Making the Poor Pay for Public Goods via Microfinance Economic and Political Pitfalls in the Case of Water and Sanitation docx
... explaining the concept of microfinance in the context of neoliberal restructuring and the rise of the vision of fragmented entrepreneurial development Section discusses the characteristics of the ... been growing in popularity approximately since the beginning of the millennium As one recent online microfinance publication observed, The latest craze in the creative use of microfinance as ... disbursement of the 50 percent subsidy; the household must complete a certain part of the construction before one half of the subsidy is disbursed and finish the sanitary works and the roof before the other...
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Policy Issues in the Development of Personalized Medicine in Oncology doc
... 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute ... become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, � and the scientific and ... the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers It is autonomous in its administration and in the selection of its members, sharing with the...
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Consumer market study on the functioning of e-commerce and Internet marketing and selling techniques in the retail of goods potx
... on the functioning of e-commerce and Internet marketing and selling techniques in the retail of goods • Many consumers research information on products and prices offline and then buy them online: ... online prices were lower than offline prices in 13 of the 15 Civic Consulting Consumer market study on the functioning of e-commerce and Internet marketing and selling techniques in the retail of ... the functioning of e-commerce and Internet marketing and selling techniques in the retail of goods Table 12: Consumer survey – Perceived savings while buying online or offline28 Online shopping...
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Policy Issues In The Development Of Personalized Medicine in Oncology docx
... 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute ... become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, � and the scientific and ... the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers It is autonomous in its administration and in the selection of its members, sharing with the...
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Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
... mislocalization of all three enzymes in these cells clearly shows the involvement of PEX14 in the targeting of PTS-1, PTS-2 and I-PTS proteins to the glycosome To further analyse the effect of the destruction ... N-terminal domain of the polypeptide of each of these organisms is followed by a stretch of hydrophobic amino acids that is presumably involved in the protein’s anchoring to the membrane Also in ... was located in the band This may be due to diffusion of some complexed protein as the band migrates in the native gel Band contains the excess of TbPEX14-N,H In a second experiment, the same two...
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Báo cáo khoa học: Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth* potx
... transporters and are involved in Na+ binding [19] Also present are conserved residues D32 in the rst TMD and S321 and S324 in TMD7, thought to be involved in catecholamine binding [20] There are ... Dopamine-like immunoreactivity ă in the brain and suboesophageal ganglion of the honeybee J Comp Neurol 280, 4358 Wendt, B & Homberg, U (1992) Immunocytochemistry of dopamine in the brain of the ... for both dopamine and octopamine [12] This raises several issues: does the moth OAT substitute for DAT in dopaminergic signaling pathways in the moth CNS, and what is the nature of the mechanism...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25