0

φ29 dna packaging motor and its potential applications in gene therapy and nanotechnology

A study on bottom spray granulation and its potential applications

A study on bottom spray granulation and its potential applications

Cao đẳng - Đại học

... film surrounding the granule and into the neighbouring fluidizing air - the rate-limiting step in the drying phase Based on the findings that an increase in inlet air humidity resulted in higher ... different influences on granule growth Binder concentration and viscosity: In general, increasing the concentration and viscosity of the liquid binder increased mean granule size and increased ... PAT initiative by the United States Food and Drug Administration, an increased interest in process understanding is seen in the pharmaceutical industry PAT is defined as “a system for designing,...
  • 234
  • 335
  • 0
Báo cáo y học:

Báo cáo y học: "Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production" ppt

Báo cáo khoa học

... remaining in the upper compartment were completely removed with gentle swabbing The filter was fixed and stained with haematoxylin and eosin The cells invading the lower surface of the filter in ... than in OA and AS synovium CD147 was expressed predominantly on the macrophage-like cells and fibroblast-like synovial cells in the lining and sublining layers (Fig 2) MMP-1 was expressed predominantly ... CD147), matrix metalloproteinase-1 (RA MMP-1), tissue inhibitor of metalloproteinases-1 (RA TIMP-1) and blank contrast (RA blank) in the lining and sublining layers in RA synovium (× 400) The...
  • 11
  • 459
  • 0
Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis pdf

Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis pdf

Báo cáo khoa học

... 2005:870-874 36 Etrych T, Jelinkova M, Rihova B, Ulbrich K: New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties ... citation purposes) retention, and release of drugs in the treatment of RA and related forms of inflammatory arthritis Competing interests DW and SCM are inventors named in a patent application partially ... solid tumors in many ways, including the leaky nature of the associated blood capillaries This leads to abnormal serum protein infiltration into the synovium and higher protein content in synovial...
  • 9
  • 311
  • 0
Báo cáo y học:

Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx

Báo cáo khoa học

... domain FL: Follistatin-like domain NtA: amino-terminal agrin domain LE: Laminin d id LE L i i and epidermal growth f t lik d l th factor-like domain i EL LGL B/z S/T: Serine/Threonine rich domain ... Agrin in motor neurons [23] These mice exhibit a reduced number of presynaptic and postsynaptic specializations in the brain, indicating that Agrin has a role, at least in part, in maintaining ... tissue remains unresolved Potential Agrin receptors in the immune system Agrin is a large HSPG containing many distinct structural domains (Figure  1), and to date several Agrin binding partners...
  • 7
  • 357
  • 0
Studies of quantum spin chain dynamics and their potential applications in quantum information

Studies of quantum spin chain dynamics and their potential applications in quantum information

Y - Dược

... spins i and j Depending upon the directions of spin-spin interaction, spin chains can be classified into three types: Heisenberg spin chain, XY spin chain and Ising spin chain In the following, ... Publications Vinitha Balachandran, and Jiangbin Gong, Adiabatic quantum transport in a spin chain with a moving potential, Phys Rev A 77, 012303 (2008) Vinitha Balachandran, and Jiangbin Gong, Controlled ... STUDIES OF QUANTUM SPIN CHAIN DYNAMICS AND THEIR POTENTIAL APPLICATIONS IN QUANTUM INFORMATION VINITHA BALACHANDRAN (M Sc., Cochin University of Science And Technology, India) A THESIS SUBMITTED...
  • 156
  • 278
  • 0
Báo cáo y học:

Báo cáo y học: " Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy" pps

Báo cáo khoa học

... emphasis on brain, prostate, pancreatic and colorectal cancers were included in the review Potential applications of curcumin in cancer prevention and therapy Curcumin exhibits in vitro and in vivo ... cancer cells and antitumoral effect on MDA-MB-231 cell xenografts in vivo by inhibiting p21WAP1, survivin and NF-B and its downstream effectors, including cyclin D1 and Bcl-2, and activating caspase ... curcumin inhibited the growth and triggered the apoptosis of AD LNCaP and AI PC3 cells in vitro by down-regulating the expression levels and intrinsic activities of EGFR and its downstream signaling...
  • 19
  • 434
  • 0
Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering

Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering

Thạc sĩ - Cao học

... depth-averaged model in a nonorthogonal curvilinear coordinates for prediction of flow pattern in meandering channel with 60o and 90o bend, and also with compound meandering channel In this study, ... in the past, including studies on depth-averaged models in Cartesian coordinates, generalized curvilinear coordinates and studies on the effect of bottom curvature It analyzes these methods and ... coordinates for predicting sea level, currents in estuarine and shelf water (Muin and Spaulding 1996) Ye and McCorquodale (1997) developed a depth-averaged model in a non-orthogonal curvilinear system...
  • 127
  • 595
  • 0
HOW TO VALUE YOUR BUSINESS AND INCREASE ITS POTENTIAL doc

HOW TO VALUE YOUR BUSINESS AND INCREASE ITS POTENTIAL doc

Kế hoạch kinh doanh

... business damages, etc.); initiating and maintaining an Employee Stock Option Plan; spinning off a portion of your business; entity restructuring; and other reasons The term “value” in and of itself ... equation, and go into the elements you can manage and the tradeoffs you face in increasing the value of your business Creating and realizing value is the long-term bottom line of owning a business.1 ... Your Business and Increase Its Potential will teach you just that: How to value your business “quick and dirty,” and how to manage it to increase its worth I have written it primarily for business...
  • 320
  • 477
  • 0
Báo cáo khoa học: Characterization of HbpR binding by site-directed mutagenesis of its DNA-binding site and by deletion of the effector domain pot

Báo cáo khoa học: Characterization of HbpR binding by site-directed mutagenesis of its DNA-binding site and by deletion of the effector domain pot

Báo cáo khoa học

... determined whether the A-domain of HbpR is important in forming the oligomeric structure and for DNA binding, by cloning an hbpR gene devoid of the A-domain, purifying this protein, and analyzing its ... the DNA The objectives of this work were to identify critical motifs in the binding site for HbpR and to examine the necessity of the sensing A-domain of HbpR for DNA binding The role of individual ... protein was correctly expressed in E coli DNA- binding characteristics of the DA-HbpR protein EMSA performed on the wild-type HbpR-binding site and increasing amounts of DA-HbpR or HbpR in fusion...
  • 11
  • 468
  • 0
DNA Sequencing – Methods and Applications Edited by Anjana Munshi pptx

DNA Sequencing – Methods and Applications Edited by Anjana Munshi pptx

Sức khỏe giới tính

... Uttarakhand, India Introduction The term DNA sequencing refers to methods for determining the order of the nucleotides bases adenine,guanine,cytosine and thymine in a molecule of DNA The first DNA sequence ... fluorescence and emission Owing to its greater expediency and speed,dye terminator sequencing is now the mainstay in automated sequencing Its limitation include dye effects due to differences in the incorporation ... Ashrafi and Natasha Paul Section Applications of DNA Sequencing 33 Chapter Sequencing Technologies and Their Use in Plant Biotechnology and Breeding Victor Llaca Chapter DNA Sequencing and Crop...
  • 184
  • 928
  • 0
Báo cáo khoa học: Ubiquitination of E3 ubiquitin ligase TRIM5a and its potential role pdf

Báo cáo khoa học: Ubiquitination of E3 ubiquitin ligase TRIM5a and its potential role pdf

Báo cáo khoa học

... proteins possess RING-finger and B-box domains in the N-terminal region In the central region, Ro52 contains two separated coiled-coil domains, whereas TRIM5a contains a fused coiled-coil domain In ... the function of its RINGfinger domain in HEK293T cells Ro52 strongly ubiquitinates itself and TRIM5a in HEK293T cells Fig E3 activity of wild-type TRIM5a and its RING mutant C15A in HEK293T cells ... func- Ubiquitination of TRIM5a and its role A B tions as an E3 enzyme in human cells To determine this, we performed an in vivo ubiquitination assay using the wild-type TRIM5a and its RING-finger...
  • 16
  • 461
  • 0
Gene Therapy - Tools and Potential Applications by Francisco Martin Molina Contributors ppt

Gene Therapy - Tools and Potential Applications by Francisco Martin Molina Contributors ppt

Sức khỏe giới tính

... vascular bed and migrate into the tumoral mass The most common entities used for tumor targeting include transferrin, epidermal growth factor, and the integrin-binding tripeptide arginine-glycine-aspartic ... to mutagenesis, with subsequent alteration in the patients protein expression profile and potentially carcinogenesis With this in mind, methods of prolonging and/ or controlling episomal gene expression ... after administration, and it was maintained for at least week In a later study [109], we incorporated dextran and protamine in the SLN and the transfection was im proved, being detected also in lung...
  • 754
  • 589
  • 0
nanostructured materials. processing, properties and potential applications, 2002, p.625

nanostructured materials. processing, properties and potential applications, 2002, p.625

Vật lý

... extensively used as main-shaft bearings in aircraft gas turbine engines because of its good resistance to wear and tempering, and rolling contact fatigue The large carbide particles in these materials ... of research and emerging applications in recent years It is one of the most visible and growing research areas in materials science in its broadest sense Nanostructured materials include atomic ... Mazdiyasni FRICTION AND WEAR TRANSITIONS OF MATERIALS: by Peter J Blau HANDBOOK OF CERAMIC GRINDING AND POLISHING: edited by Ioan D Marinescu, Hans K Tonshoff, and Ichiro Inasaki HANDBOOK OF HYDROTHERMAL...
  • 625
  • 397
  • 0
Báo cáo hóa học:

Báo cáo hóa học: " Research Article Parametric Time-Frequency Analysis and Its Applications in Music Classification" pdf

Hóa học - Dầu khí

... classification accuracy rate Since each sample is excluded from the training set in turn, the independence between the test set and the training set is maintained In a database with N examples, ... [3] S Krishnan and R M Rangayyan, “Automatic de-noising of knee-joint vibration signals using adaptive time-frequency representations,” Medical and Biological Engineering and Computing, vol 38, ... Inc., “SPSS advanced statistics user’s guide,” in User Manual, SPSS Inc., Chicago, Ill, USA, 1990 [12] M Shan, F Kuo, and M Chen, “Music style mining and classification by melody,” in Proceedings...
  • 9
  • 444
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "Capsular polysaccharide typing of domestic mastitis-causing Staphylococcus aureus strains and its potential exploration of bovine mastitis vaccine developmen" docx

Báo cáo khoa học

... shown to bind to specific epithelial cell surface receptors, the binding being defined as lectinligand interaction [5] Studies on S aureus suggested that these interactions may be involved in the ... cultures of CP8 and 0.7ß² from the same amount of cultures of CP5 The protein content in the finally obtained CP was 1.2% in CP8 and 2.3% in CP5, respectively To determine CP concentration in the culture ... serotyping and its detection in culture supernatant Cells were suspended in PBS containing lysostaphin (100 µg/ml), and then incubated at 37oC overnight The suspension was autoclaved at 121oC for 60 min,...
  • 8
  • 273
  • 1
báo cáo khoa học:

báo cáo khoa học: " Epiglottis reshaping using CO2 laser: a minimally invasive technique and its potent applications" doc

Báo cáo khoa học

... alignment and drafted the manuscript GV participated in the sequence alignment EH conceived of the study, and participated in its design and coordination All authors read and approved the final manuscript ... preliminary and further research in vivo is required Currently a series of experiments is being conducted on animals (canines) in an effort to determine the efficacy of this method on living specimens ... using different types of laser (CO2, Er: glass) as well as the healing process and possible complications The next step is to design a clinical trial in selected patients suffering of OSAS and...
  • 4
  • 297
  • 0
ITERATIVE VISUAL ANALYTICS AND ITS APPLICATIONS IN BIOINFORMATICS

ITERATIVE VISUAL ANALYTICS AND ITS APPLICATIONS IN BIOINFORMATICS

Xã hội học

... networks, including genome-scale integrated works of protein-protein, protein -DNA and genetic interactions; the VisANT project [125] dose not only support simultaneously visualizing and overlaying ... relating unfamiliar or new phenomenon to something in the existed knowledge schema And human beings master a compendium of reasoning and problem solving heuristics, e.g eliminating pertinent information ... perception, intelligence and reasoning capability, and cooperates with the automatic computing in solving complex real-world problems Earlier research in VA and its relevant applications set the stepping...
  • 116
  • 285
  • 0

Xem thêm