... case, we asked the PWGSC contracting officer why the 10% profit invoiced bythe subcontractor had been approved when there was no mention of it in the basis of payment The contracting officer told ... that despite the fact that no mention of profit was made in the basis of payment, it was the intention ofthe contracting authority to authorize such a profit The PWGSC contracting officer told ... conditions ofthe contract When we examined the 27 contracts, we compared the request for payment with the contract’s basis of payment to see if the two matched The audit showed that for 23 ofthe 27...
... amounts of SE (A) Quantification of SE in cell polarity mutants Cells ofthe indicated strains were grown to stationary phase and then lipids were extracted and separated by TLC The amount of SE ofthe ... affect sterol biosynthesis during the formation of a mating projection Nevertheless, the phenotypes of mutants defective in ergosterol synthesis clearly demonstrate the importance of sterols for polarization ... of protein from the homogenate of cells grown to logarithmic phase [69] This method relies on the measurement ofthe amount of radiolabeled steryl esters formed during the assay relative to the...
... for the indicated times in buffer F (DAPA was included to inhibit the feedback proteolysis of prothrombin bythe generated thrombin) The reaction was stopped bythe addition of an equal volume of ... activation of human prothrombin was determined by measuring the generation of thrombin using the chromogenic substrate Spectrozyme TH, in the presence ofthe indicated concentrations of plactin ... conversion of scu-PA to the two-chain form The apparent molecular masses ofthe resulting polypeptide chains were comparable with those ofthe A- and B-chains of tcu-PA (an A-chain doublet was caused by...
... suggested that the N-terminal a-helix of CB1 is located on the surface ofthe lipid bilayers, whereas the C-terminal a-helix of CB1 is embedded below the surface ofthe lipid bilayers These conclusions ... DSC analysis ofthe effect of peptides on PtdEtn/PA LUV thermotrophic phase behaviour The effect of CB, CB1 and CB3 on the thermotrophic phase behaviour of LUVs is shown in Fig The phase-transition ... sample loss caused bythe adsorption of hydrophobic molecules to the surfaces ofthe flow system ofthe BIAcore instrument Peptides dissolved in HBS-EP buffer are not lysed bythe liposomes Avidin...
... structures ofthe b-amino acids that best fit are shown in Fig They all correspond to gauche(+) values ofthe h angle The methyl group of b2-HAla occupies a position close to that of CH2b of Pro or the ... the expense of a minimal decrease in its activity HGly (named bythe authors b-alanine) has been previously introduced in the sequence ofthe C-terminal heptapeptide of NKA, another peptide of ... w) values ofthe selected Pro conformer are ()72°, 153°) The low-energy conformers of b-HAla generated in the grid calculation have been selected on the basis ofthe best fit with Pro They correspond...
... instead of lowering the interest rate according to the policy adopted bythe Conference of Bankers at the beginning ofthe year, the State Bank preserved the status quo on the grounds that the inflation ... determined bythe central bank and announced on the basis of real situation and targets ofthe national monetary policy The point 12, Article ofthe Law on the State Bank of Vietnam stipulates: " The ... among the banks Deposit side vs Lending side: The utility package offered bythe banks to the depositors mainly includes the interest rate, the quality of service, and the credibility If the banks...
... periods of great anxiety about the terminal illness of a loved one or the health of a young child In one case, the decision to remove the patient was made bythe member of staff involved in the altercation ... with national leaders, from the Chief Executive ofthe NHS to the leaders ofthe professional bodies and regulators Our report was quickly followed bythe CQC’s programme of unannounced inspection ... consider other courses of action the response They asked theThe Practice also took Miss F’s Ombudsman for help Miss F said mother off their list even though 18 she had not been involved in the disagreement...
... width of 1.0 mm The wavelength range ofthe spectrometer was 370– 820 nm Experimental conditions are described in the legend of each figure R E S U LT S Formation of glyoxal in the reaction of linoleic ... linoleic acid by MnP in any ofthe buffer systems (Fig 1) Syn and q FEBS 2001 anti-isomers of these PFBO derivatives were separated on the GC/MS column The mass spectrum of PFBO derivatives of glyoxal ... PFBO derivatives of glyoxal formed bythe oxidation of linoleic acid with MnP (A) and authentic standard (B) (A) Glyoxal formed bythe oxidation of linoleic acid with MnP for 19 h The reaction system...
... indicating that these RNAs are not efficiently processed or degraded bythe exosome in the absence of Nop53p In order to determine whether the effect of Nop53p depletion on 5.8S processing bythe exosome ... degrade RNA by itself, its presence stimulates the RNase activity ofthe exosome It is possible that the stimulation ofthe exosome activity is due to recruitment ofthe complex to the substrate ... extension ofthe 7S pre-rRNA and formation ofthe mature 5.8S rRNA [13] Interestingly, despite being directly involved in the late steps of processing, depletion of essential subunits ofthe exosome...
... expression of type I collagen (Col1a1) in the condensed mesenchyme ofthe membranous skeleton and the periosteum and mesenchyme ofthe endochondral skeleton is severely reduced Expressions ofthe osteoblast-specific ... regulator of postnatal bone mass 11 Dlx5 delayed ossification ofthe roof ofthe skull and abnormal osteogenesis positive regulator in OB differentiation 12 reading frame (ORF) and 3-prime UTR The ... Osx-null embryos the number of TRAP-positive cells appear to be reduced compared to wild-type embryos In long bones of Osxnull embryos cells from the periosteum invade the zone ofthe hypertrophy...
... Values ofthe optical band gap for the samples were obtained bythe extrapolation ofthe linear region ofthe plot of (ahv)1/2 against photon energy (hv) as shown in Fig 4(c) Clearly, the absorption ... to be dependent on the nature ofthe stabilizing agents used in addition to the thermal conditions ofthe preparation Isotropic and anisotropic growth of SnS NCs is achieved by use different capping ... the synthesis of high quality semiconductor SnS NCs due to its low cost and low toxicity As indicated bythe thermoanalytical data [13, 14], the substantially complete thermal decomposition of...
... Values ofthe optical band gap for the samples were obtained bythe extrapolation ofthe linear region ofthe plot of (ahv)1/2 against photon energy (hv) as shown in Fig 4(c) Clearly, the absorption ... to be dependent on the nature ofthe stabilizing agents used in addition to the thermal conditions ofthe preparation Isotropic and anisotropic growth of SnS NCs is achieved by use different capping ... the synthesis of high quality semiconductor SnS NCs due to its low cost and low toxicity As indicated bythe thermoanalytical data [13, 14], the substantially complete thermal decomposition of...
... The zero ofthe scale shall indicate that position at which the center lines ofthe slots for the light beam are at the same elevation as the surface ofthe liquid in the tank when filled to the ... adjusted so that the turbidity ofthe suspension may be determined at any desired depth The center ofthe light source, the heat absorbing device, the photocell, the center ofthe slots ofthe metal ... past the corresponding mark on the buret 8.3.8 Lower the shelf to the 30–50 µm position Replace the filter in the path ofthe light beam, remove the tank, and check the intensity ofthe lamp If the...
... and the beads lodged in the meshes are difficult to remove Tapping the frame ofthe sieve and gentle brushing ofthe cloth from the underside will aid in recovering all the beads and keep the ... important that the sample for calibration be ofthe same typical fineness as the range at which the sieve is to be used Determine the percent residue ofthe test material on each ofthe three sieves, ... through the center If one ofthe lines is marked with an arrowhead and the habit of starting with this point under the right hand has been formed, one can easily follow the progress ofthe 1-min...
... at the rate of one motion per second in the spray The bottom ofthe spray nozzle should extend below the top ofthe sieve frame about 12 mm (0.5 in.) Immediately upon removing the sieve from the ... determination ofthe validity of any such patent rights, and the risk of infringement of such rights, are entirely their own responsibility This standard is subject to revision at any time bythe responsible ... (0.51-mm) Holes Calculation 7.1 Calculate the fineness ofthe cement to the nearest 0.1 % as follows: proportional to the amount of residue Example of Determination of Sieve Correction Factor: Residue...
... Inspectorate in the implementation of social policies Determining the content of inspection Approving the content of inspection bythe leaders ofthe Government Inspectorate Approvalbythe Prime Minister ... Apart from the effect of reorganizing the operation, compliance with the laws, the policies ofthe Communist Party of Vietnam and the State of Vietnam, large-scaled inspection bythe Government ... agencies, one of three to-do works ofthe leadership ofthe Communist Party of Vietnam and governments at various levels, an integral part ofthe leadership ofthe Communist Party of Vietnam and the State...
... thioester bond between the active-site cysteine ofthe E1 and the carboxyl terminus of ubiquitin The E1 then transfers the activated ubiquitin to the active-site cysteine of an E2, or ubiquitin-conjugating ... Finally, the E3, or ubiquitin-protein ligase (green), facilitates the transfer ofthe ubiquitin from the E2 to a lysine on the target protein (substrate, magenta) In the case ofthe APC and many other ... member ofthe RING-domain family of E3s These proteins facilitate the final step in ubiquitination by positioning the E2-ubiquitin conjugate next to the substrate, allowing the ε-amino group of a...
... [15] and the lab of Susan Golden [21], in addition to the study of Nakahira and coworkers [16], are consistent with this hypothesis, namely that the condensation or supercoiling status ofthe cyanobacterial ... the only target of KaiC, however; the recent paper by Nakahira and coworkers [16] reports the unexpected result that KaiC overexpression represses the rhythms of all promoters in the S elongatus ... identified two classes of response to KaiC repression The first class, termed ‘high amplitude’ by Nakahira and coworkers [16], was exhibited by 5-10 % ofthe promoters, including kaiBCp; these promoters...
... Kampung Bawong (Table 1) Most of these species grow in the wild naturally and their medicinal properties are crucial in traditional medicine ofthe Orang Asli Majority ofthe species reported in this ... for a large number of medical conditions The plants were often used by most ofthe informants more or less for the same purpose, and with only slight variations in recipes The plants are usually ... Rhizomes Juice ofthe rhizomes is used for the treatment of stomach pains and coughs Zingiber ottensii Valeton Kunyit Terus Hitam Rhizomes The juice ofthe rhizomes is used to cure all types of bacterial...
... inhibitor of NFκB activity [12,13] The overall goal of this study was to characterize the effect of this compound on NFκB in cellular models of CFrelated inflammation In our studies, filtrates of PA ... mutation and the CF 14 clinically isolated mucoid strain of PA (originally from the laboratory of Dr M.C Wolfgang, University of North Carolina) were donated by Dr S Randell (University of North ... fluorescence in nuclei of KKLEB cells as demonstrated in the bottom row fashion by ~70% in the KKLEB cells Inflammation in CF is regulated largely by activation of NFκB and transcription of pro-inflammatory...