MỘT SỐ ĐẶC ĐIỂM DỊCH TỄ, LÂM SÀNG, CẬN LÂM SÀNG CỦA VIÊM THẬN DO LUPUS

MỘT SỐ ĐẶC ĐIỂM DỊCH TỄ, LÂM SÀNG, CẬN LÂM SÀNG CỦA VIÊM THẬN DO LUPUS Phạm Văn Bùi*, Nguyễn Thanh Hiệp** T MT T Đặt vấn đề: SLE - BN VTL Đ it ng v ph ng ph p nghi n ứu: 2/2007 t u : 3 t u n: Từ khóa: ABSTRACT SOME EPIDEMIOLOGIC, CLINICAL, SUBCLINICAL FEATURES AND RENAL HISTOLOGICAL LESIONS OF LUPUS NEPHRITIS Pham Van Bui, Nguyen Thanh Hiep * Y Hoc TP Ho Chi Minh * Vol 14 - Supplement of No - 2010: 111 - 117 Background: Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organs The kidney appears to be the most commonly affected, occurring in 60-75% of cases with SLE The presence and extent of kidney involvement greatly influence the long-term outcome of the disease WHO classifications of glomerular lesions tend to correlate with several clinical, subclinical features, and provide guidelines for treatment The aim of this study was to review several epidemiologic, clinical and subclinical features, renal histological lesions, as well as to evaluate the correlation between those features and WHO classifications of lupus nephritis (LN) in patients managed and followed at the Department of Nephrology and Urology, Patients and Method: w ’ - f patients from 02/2004 to 02/2007 Results: Of 40 LN studied, 87.5% were women In the majority of cases (70%), LN developed within year of SLE diagnosis The three most common clinical manifestations were edema (92.5%), hypertension (47.5%) and pallor (55%) There were 85% patients having Hb[...]... th n upus Lu n v n th c s chu n ng nh n i h a ng bệnh ng c p HCM Uthman IW, Muffarij AA, et al (2001), Lupus nephritis in Lebanon Occasional series: Lupus around the world Lupus, 10: 378-381 24 Williams et al (2004), The clinical and epidemiologic features in 140 patients with lupus nephritis in a predominantly black population from one center in Kington, Jamaica Am J Med Sci 327 (6):324-329 ... pathological findings in patients with Lupus nephritis: a five year experience in Iran Saudi J Kidney Dis Transpl 19(1):32-40 19 Nguyễn Thị Ng h c 20 M (2002 i gi ng: ệnh da i u Nh u tb nY : 353-366 Shayakul C, Parichatikanond P et al (1995), Lupus nephrits in Thailand: Clinicopathologic findings and outcome in 569 patients Am J Kidney Dis 26 (2):300–307 21 Shur P.H (2000 “ ste ic Lupus E uthe at sus” Ceci ’s... patients with systemic lupus erythematosus Journal of the Nephrology Society of Thailand 12:178–187 Bevra HH (2001 “ 2 ste ic upus e the t sus” Ke ’s e tb f Rheumatology, 6th ed W B Saunders, pp: 1089–1136 3 Bevra HH (2005 “ ste ic Lupus E the at s us” Ha is n’s principle of internal medicine, 16th ed Chapter 300: 1960–1967 4 Brugos B, et al Retrospective analysis of patients with lupus nephritis: data... tốt nghiệp b c s n i t ú chu n ng nh nhi đ ih c d 13 u t ng c P HCM Francis ND, Parichatikanond P et al (1986), Lupus nephritis: clinicopathological study of 162 cases in Thailand J Clin Pathol 39:160-166 14 Gan HC, Yoon KH, Fong KY (2002), Clinical outcomes of patient with biopsy-proven lupus nephritis in NUH Singapore Medical Journal, 43(12):614-616 15 Lê Kinh Duệ (2000 ệnh upus đỏ u t t đi n b ch... data from a large clinical Immunological Center in Hungary 5 Cameron J.S (2000), Lupus nephritis Journal of the american Society of nephrology 11(12):413 – 423 Cassidy J.T (1995 6 “ ste ic upus e the t sus” e tb f Pediatric Rheumatology, 3rd ed, W B Saunders; pp: 260–301 7 Charles K L, David A Isenberg (2006), Systemic Lupus Erythematosous Elsevier Pages 445–452 Châu Thị Kim Liên (1992 Nh n 8 th ng... đỏ Lu n v n tốt nghiệp n i t ú h a X chu n ng nh n i 9 t ng ih cYd c p HCM Chi Chiu Mok (1999), Lupus nephritis in Southern Chinese patients: Clinicopathologic findings and long-term outcome American Journal of kidney diseases, 34(2):315-323 10 Đỗ Kháng Chiến, Phạm Thị Hoan, Nguyễn Văn Sang (1985 Nh n t số đ c đi vi c u th n upus h a th n bệnh viện ch t ai Y h c th c h nh 258 (4 :32-35 11 Đỗ Thị Liệu... ng LE cv ang nhi u t n th t đa d ng v c ng cđ n ng ng 40 t ng h p đ c sinh thi t th n ( nhi u nh t 70% K t u n he C K Li n(7) nh 27 3% s h c biệt n c u gi c th n v c th c c t he tỉ ệ ca nh t 31 8% nh d số N đ c ng nghi n c u c a chúng t i nh h c đi u n v n th nh d c c Nđ ng h p n I th c t n th I chi I I g p chỉ chi t ng nghi n tỉ ệ ca h n s v i c c t c nh đ nh gi t n th s ng đ c bi u hiện t n th ng h... sinh thi t s t n Nghi n c u c a chúng t i c sang th t c gi ; v nh ng nh giống h u h t c c nghi n c u h c (33 3 – 84%) II chi c sang th ng nh ng th n v chi ng ng th n h ng c n sinh thi t tỉ ệ th p s v i t số h c biệt s v i c c t c gi Chúng t i h ng I giống h u h t c c t c gi c N nh Iđ giai đ n cuối v i th n (22) t n th h a v te ch n n chỉ đ nh I 2 94% c n the Uth an IW(23) ng nh Ng i c u th n t n th ng ... n đ t bệnh t c hi u n su t c bệnh t n th gi i tha đ i t 12-64/100 000 d n(7) t i iệt Na ch a c số iệu thống v d ch t h c nh ng ua c c nghi n c u ch th c ng gia t ng(12,8, 1922,) uh nhi u hệ thống... nhi u L t t ng nh ng c ng N tỉ ệ 60-75% bệnh nh n (BN) SLE(11) nh t chi đ c c t ng c a bệnh LE số t nghi n c u v i s ng t n th h s t ng c ti u t v h c th n c a c c N ối i n uan gi a c c đ c đ... t n th ng h c th n đ c ph n v hiệu chỉnh 1997 Ng i a N đ th nhi b it b tối thi u c u th n v C c số iệu đ h pv đ n nh n v phù h ng c ngu n nh n c thống s t b ng c c ph p i Fishe t tudent c i d