universal multifunctional nanoparticles for bio sensing imaging for diagnostics and targeted drug delivery for therapeutic applications
multifunctional nanorods for biomedical applications
... Nanowires for Use in Biomedical Applications and/ or Self Assembly 2342 Pearce, Melanko and Salem Multifunctional Nanorods for Biomedical Applications ers a way to perform thousands of simultaneous assays ... have Multifunctional Nanorods for Biomedical Applications cellular, tissue, and organismal phenotypic manifestations (70) A wide variety of nanorods and wires have been utilized in biological applications, ... single-molecule biosensors Nano Lett 3:727–730 (2003) 87 K S Lee and M A El-Sayed Gold and silver nanoparticles in sensing and imaging: Sensitivity of plasmon response to size, shape, and metal composition...
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Conjugated polymer nanoparticles for bioimaging applications
... POLYMER NANOPARTICLES FOR BIOIMAGING APPLICATIONS GENG JUNLONG (M.S University of Science and Technology of China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL AND ... PFTTQ NPs and Au NRs before and after laser irradiation with a power density of 15 mJ/cm2 for mins FE-TEM images of PFTTQ NPs (C) and Au NRs (D) before (1) and after (2) laser irradiation for mins ... photoacoustic (PA)[12-14] and fluorescence imaging[ 15-17] have been widely utilized to achieve reliable and accurate biodetection and bioimaging Among these strategies, the fluorescence imaging technique...
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Báo cáo khoa học: Designing highly active siRNAs for therapeutic applications pdf
... Methods Mol Biol 487, 41– 59 Shim M & Kwon Y (2010) Efficient and targeted delivery of siRNA in vivo FEBS J 277, 4814–4827 Sioud M (2009) Targeted delivery of antisense oligonucleotides and siRNAs ... human system and proteins is essential for the development of therapeutic siRNAs for human disease.) RISC then recognizes its target mRNA by complementarity between the guide strand and a region ... NM & Micklefield J (2009) Chemical modification of oligonucleotides for therapeutic, bioanalytical and other applications Chembiochem 10, 2691–2703 57 Chu CY & Rana TM (2008) Potent RNAi by short...
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báo cáo khoa học: "Phenotype and functional evaluation of ex vivo generated antigen-specific immune effector cells with potential for therapeutic applications" pps
... responsible for the conception of the research and Han, Huang, Liang, Ho and Wang are responsible for the execution and for data collection; Chang is responsible for initial drafting and revisions ... APCanti-CD40 and FITC-anti-HLA-I (BD Biosciences, San Jose, CA, USA), APC-anti-DC-SIGN and PE-cy7-antiCD11c (eBioscience), and incubated for 30 at 4°C Isotype-matched antibodies were used for controls ... GM-CSF and 25 ng/ml IL-4 (eBiosource International, Inc Camarillo, CA, USA) For the generation of day DC, the adherent cells were cultured with GM-CSF and IL-4 for 24 h and incubated for another...
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báo cáo khoa học: "Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis" pptx
... delivery for treatment of CF We anticipate that this study will have a high impact on the development of novel targeted drug- delivery therapeutics for CF and other airway diseases like COPD and ... targeting and gene therapy Trends Biotechnol 1997, 15:217-224 11 Panyam J, Labhasetwar V: Biodegradable nanoparticles for drug and gene delivery to cells and tissue Adv Drug Deliv Rev 2003, 55:329-347 ... Regulator and Suppresses Interleukin-8 Levels: THERAPEUTIC IMPLICATIONS J Biol Chem 2006, 281:17369-17378 10 Davis SS: Biomedical applications of nanotechnology–implications for drug targeting and...
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Stimuli responsive PEGylated nano assemblies for cancer targeted drug delivery
... nanocarriers and encompassed methods of fabricating nanocarrier-based drug delivery systems for controlled and targeted therapeutic application Chapter provides general information of cancer and cancer ... Breast cancer imaging Brain tumor imaging and therapy Integrin positive cell imaging Inflammatory disease imaging Breast cancer imaging Brain tumor imaging and therapy Apoptosis imaging Cardiovascular ... nanotechnology in medicine and more specifically drug delivery is set to spread rapidly Currently many substances are under investigation for drug delivery and more specifically for cancer therapy are...
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Báo cáo hóa học: " Fluorescence Modified Chitosan-Coated Magnetic Nanoparticles for High-Efficient Cellular Imaging" pdf
... oxide nanoparticles (Fig 1) The high cellular affinity and imaging efficacy of the nanoparticles have extensively been investigated using MRI and optical imaging Experiments Preparation and Characterization ... molecules and quantum dots (QDs) are most predominantly used for biological staining and optical labeling [18–23] Considerable research has been devoted to the combination of magnetic and fluorescent ... contacted MNPs surface and the possible energy transfer occurring with metal oxide particles Nevertheless, there was still sufficient emission for biological imaging The strong and stable fluorescence...
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Báo cáo hóa học: " Nanoparticles for Applications in Cellular Imaging" pot
... cellular imaging and delivery The major types of nanoparticles that have been used for cellular imaging include polymer/biomacromolecular nanoparticles, semiconductor nanoparticles, and metal nanoparticles ... Therefore, by conjugating the ligands of these receptors to nanoparticles it is possible to achieve cellspecific internalization for potential drug delivery or imaging Human Serum Albumin nanoparticles ... these types of nanoparticles has different properties that permit binding of proteins and nucleic acids that can be used for cellular and intracellular targeting Nanoparticles for Imaging in Fixed...
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báo cáo khoa học: "BRCAA1 monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo targeted magnetofluorescent imaging of gastric cancer" ppsx
... great progress For example, nanoparticles such as quantum dots, magnetic nanoparticles and gold nanorods, etc have been used for molecular imaging [12-19] So far several small animal imaging technologies ... with strong fluorescent signals and excellent magnetic properties, and have used them for bio- labeling, tracking stem cells, bio- separation, targeting imaging and hyperthermia of tumors [29-32], ... of mm in diameter and IVIS imaging system and Magnetic Resonance Imaging, investigated the feasibility of as-prepared nanoprobes for non-invasive in vivo targeted dual modal imaging of gastric...
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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications
... magnetic nanoparticles could be designed for the potential applications in targeted and controlled drug delivery 2.3 Biomedical Applications of SPIONs 2.3.1 MRI Molecular imaging, such as optical imaging, ... potential for various biomedical applications, including MRI for cell targeting and monitoring, drug/ gene delivery, hyperthermia for cancer treatment, etc In addition, in contrast to other inorganic nanoparticles, ... magnetic nanoparticles to be used for optical applications (Daniel and Astruc 2004; Lee et al 2008) It was suggested that gold-coated magnetic nanoparticles could be promising for applications in biomedicine...
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Surface modification of NaYF4 yb,er upconversion nanoparticles for bio application
... summarize UC nanoparticles6 7, 81-83 for bio- applications and also compared UC nanoparticles and QDs.84 1.5.1 In vitro cell imaging Cell imaging is an important technology platform to understand the ... issues for UC nanoparticles to be used for various commercial applications For cell and tissue imaging, UC nanoparticles with size ranging from ten to one hundred nanometers are needed For DNA and ... be studied 1.5 UC nanoparticles for bio- applications UC nanoparticles are very promising as a luminescent probe for biological applications. 48, 49, 62 The main advantage of UC nanoparticles is...
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Nanomedicine multifunctional nanoparticles of biodegradable polymers for cancer treatment
... nanocarriers for drug delivery as well as the advantages over commercial drug formulations and traditional drug delivery carriers The study creates a new platform of nanotechnology based nanomedicine formulation ... (Farokhzad and Langer, 2009; Ferrari, 2005; Sinha et al., 2006) Nanoparticles (NPs) of biodegradable polymers have become promising platforms for sustained, controlled and targeted drug delivery ... Strategy for Precision Engineering of Nanoparticles of Biodegradable Copolymers for Quantitative Control of Targeted Drug Delivery 132 6.1 Introduction 133 6.2 Materials and...
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Beta cyclodextrin conjugated magnetic nanoparticles for bio and environmental applications
... has numerous applications in biotechnology and biomedical diagnostics such as cell sorting, nucleic acid detachment, enzyme immobilization, drug delivery and protein adsorption and purification ... model drug Our preliminary results suggest that such core-shell nanocomposite can be a smart theranostic candidate for simultaneous bioimaging, magnetic control, cancer celltargeting and drug delivery ... their application in biological systems, including their application in magnetic resonance imaging (MRI), targeted drug delivery, rapid biological separation, biosensors, and magnetic hyperthermia...
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Use of upconversion fluorescent nanoparticles for simultaneous imaging, detection and delivery of sirna
... types and characteristics of fluorescent nanoparticles, in vitro and in vivo imaging of cancer using fluorescent nanoparticles, and multifunctional nanoparticles for simultaneous tumor imaging and ... importantly, nanoparticles are capable of combining different modalities (targeting, imaging, drug delivery and sensing) on one particle, which leads to multifunctional nanoparticles for simultaneous ... are known for their versatility and various multifunctional nanoparticles capable of simultaneous imaging, delivery etc are used For example, a multifunctional micelle was developed for in vitro...
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Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer
... rate and hydrophobic/hydrophilic balance and develop the copolymer nanoparticles for cancer chemotherapy and imaging, as well as to prepare targeted nanoparticles for cancer therapy and imaging ... sustained imaging for cancer diagnosis at its early stage 4) to prepare biodegradable polymeric multifunctional nanoparticles for targeted chemotherapy and imaging with docetaxel as model drug and ... its therapeutic effects and reduced its side effects Next, a new strategy was developed to prepare folate-decorated nanoparticles of biodegradable polymers for QDs formulation for targeted and...
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Microgel iron oxide nanoparticles for tracking of stem cells through magnetic resonance imaging
... Singapore Bio- Imaging Consortium (SBIC) of the Agency for Science, Technology and Research (A*STAR) First of all, I would like thank Professor Wang Shih-chang and Professor Teoh Swee Hin for their ... Serena, Ginny and Pascale for their administrative support and Mathieu for the French translation of the abstract I would like to thank my family – my parents Lawerence and Florence Lee, and sister ... specific for MSC, it is generally accepted that MSC from any source not express haematopoietic markers such as CD14, CD34 and CD45 and are negative for the endothelial markers CD31 and von-Willebrand...
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Funtionalization of magnetic nanoparticles for bio applications
... INTRODUCTION In recent years, magnetic nanoparticles have been proposed for use in a number of biomedical applications such as drug delivery, hyperthermia and chemotherapy and as radiotherapy enhancement ... magnetic nanoparticles to render them suitable for biomedical applications such as drug delivery, tumor-targeting and hyperthermia Two different approaches were used Iron oxides, namely Fe3O4 and ... the nanoparticles in formamide, the medium used for heparin immobilization Recent trends have shown that poly(NIPAAM) can be used for a number of potential biomedical applications such as for drug...
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Tài liệu Universal Transport Platform for Access Networks doc
... λ Universal Transport Platform for Access Networks The DWDM-PON architecture (presented below) removes the bandwidth bottlenecks on the feeder fiber in the existing broadband access networks and ... Express™ 16 λ Universal Transport Platform for Access Networks Express™ 16 Optical Line Termination Shelf (OLT) OLT shelf with BMS, OCU, MPU, PSU slots Dimensions: 19” x 5RU (4RU OLT and 1RU Fan) ... termination D of optical signal to RJ45 • ll ONT modules are colorless and interchangeable A for easy inventory management and plug -and- play operation • ymmetrical dedicated 1.25Gbps GE with S transparent...
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Báo cáo toán học: " Universal and efficient compressed sensing by spread spectrum and application to realistic Fourier imaging techniques" ppt
... indices chosen independently and uniformly at random from {1, , N }, and y = Ac α ∈ Cm , with Ac = Φ∗ CΨ For some constants < ρ < log3 (N ), Cρ > 0, and universal sensing Ω bases Φ ∈ CN ×N , ... signal x with a random waveform and randomly under-sample the result in time-domain The random convolution is performed through a random pre-modulation in the Fourier domain and the signal thus ... is called a universal sensing basis if all its entries φki , k, i N , are of equal complex magnitude For universal sensing bases, e.g., the Fourier transform or the Hadamard transform, we have...
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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx
... PEG and water-soluble chitosan Biomaterials 2009, 30:2340 Sun C, Sze R, Zhang M: Folic acid-PEG conjugated superparamagnetic nanoparticles for targeted cellular uptake and detection by MRI J Biomed ... nanoparticles × 100 Weight of nanoparticles Loading efficiency (% ) = Weight of drug in the nanoparticles × 100 Weight of the feeding drug In vitro drug release study The drug releases were carried ... Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting Pharm Res 2000, 17:1250 Hejazi R, Amiji M: Chitosan-based gastrointestinal delivery systems...
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