turning the camera with the mouse position
báo cáo hóa học: " Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy" ppt
... half of them were directly adjacent to the endothelial cells of the vascular tufts Hyalocytes were identified by their position above the inner retinal vascular layer (i e in the vitreous), their ... stained with lectin showing the regions used for evaluation Vascular tufts are located at the border of the central avascular zone and the peripheral zone (B) Cryosection of the eye showing the superficial ... in the deep layer, the superficial layer, and the layer above the internal limiting membrane (hyalocytes: round cells without ramification but with positive lectin stain) while observing them...
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Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps
... candidate therapeutic agents [23,24] In this study, we used the Hh overexpression mouse model to elucidate whether the PCSCs arise from P63+ basal/stem cells and to examine whether these cancer ... tagged with green fluorescence protein (GFP) sequence driven by a CMV promoter The vehicle control pCX-IG vector contains the same CMV promoter and the GFP tag, but without the Shh insert Therefore, ... the tumorigenic activation of basal/ stem cells and their progression toward a metastatic status under the influence of Hh signalling remain to be further elucidated To further characterize the...
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THE MOUSE, THE BIRD, AND THE SAUSAGE - GRIMM’S FAIRY TALES
... to the sausage to bring in the wood, to the mouse to cook, and to the bird to fetch the water And now what happened? The sausage started in search of wood, the bird made the fire, and the mouse ... mouse put on the pot, and then these two waited till the sausage returned with the fuel for the following day But the sausage remained so long away, that they became uneasy, and the bird flew ... agreed to make the best of things and to remain with one another So now the bird set the table, and the mouse looked after the food and, wishing to prepare it in the same way as the sausage, by...
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Tài liệu Báo cáo khoa học: Development of a new method for isolation and long-term culture of organ-specific blood vascular and lymphatic endothelial cells of the mouse pdf
... examine the endothelial cell biology of the mouse, and will accelerate the molecular and cellular analysis of ECs and their heterogeneity in various vascular beds 1994 Construction of the transgene ... endothelial cells through an endothelial-to-mesenchymal transition during early development [33] The presence of these cells may cause a dysfunctional cardiac flow and cause the sudden death of the ... cloning the SV40T Ag cDNA The cDNA encoding the wild-type SV40T Ag and the 3¢ portion of the tsA58T Ag cDNA carrying the A438V mutation were PCR-amplified from COS-7 cDNAs using the following primers:...
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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... reaction with the iron metal at the active site The presence of iron is therefore a prerequisite for its effect and suggests that the absence of reactivity with the MnSOD mutants is due to the lack ... than 10% with little or no structural changes in the mutants [27] Although low with either metal, the Q146H mutation was reported to give similar activities with either iron or manganese in the reconstituted ... presented with both, whether in vivo or in vitro [3,4] Second, specificity of the reaction is determined by the metal ion: the enzyme is active only with the ÔcorrectÕ metal Although, in the complete...
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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc
... region of mouse a3 integrin gene The map (upper line) shows the organization of exons 1–3 and the 5¢-flanking region with the positions for HindIII (H) and EcoRI (E) The restriction map for the 5¢-flanking ... the PCR reaction mixture in the absence of the cDNA library gave one band corresponding to that with the highest mobility (Fig 5, lane 2) Thus, we conclude that the most prominent band with the ... (Fig 9) The binding activity appeared to be specific for the Ets consensus site as the binding competed with the excess unlabeled wild-type, but not with the mutant oligonucleotide DISCUSSION The...
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Tài liệu Turning the Page The Future of eBooks ppt
... Like the Kindle, the Nook is available with only wi-fi, or with wi-fi and a 3G mobile connection The Nook is priced competitively with the Kindle, but instead of the Kindle’s physical keyboard, the ... On the other hand, publishers in the Netherlands and Germany are more conservative in their approach to digitizing their book holdings As recently as summer 2009, the range of eBooks in the Netherlands ... generic solution, as further tablets will be launched on the market in the course of the next few months Turning the Page: The Future of eBooks 17 like to read On the other hand, nonbuyers tend...
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Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf
... Molecular modeling of the 3D structure of the mSMOl isoform was thus carried out in order to test the hypothesis that the 277–307 region and the protein domain encoded by the exon VIa could be ... substantiate the hypothesis that these two structural regions are mandatory for the nuclear localization of mSMOl, as the only difference between mSMOl and mSMOlD proteins consists of the lack of the ... targeting to the nucleus Fig Stereo representation of the modelled 3D structure of the mouse spermine oxidase catalytically active splice variant, mSMOl The molecular surface of the protein is...
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Báo cáo khoa học: Transcription termination at the mouse mitochondrial H-strand promoter distal site requires an A/T rich sequence motif and sequence specific DNA binding proteins pptx
... proceeds until the end of the D-loop, overlapping with the HSP [19,20] In the mouse system, the 3¢ end of the D-loop H-strand RNA maps to the CAA sequence ending at nucleotide 16 295 of the genome ... (lane 3) Further, the two wash fractions (lanes and 5) and also the fraction eluted with 0.2 M KCl (lane 6) did not form complexes with the DNA probe The 0.5 M and M KCl eluates, on the other hand, ... sequences of the L-strand D-TERM DNA and H-strand mt-TERM DNA probes as well as their positions on the mouse mt genome are shown Mutant probes are the synthetic D-TERM DNA probes with nucleotide...
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Báo cáo khoa học: Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue pot
... attack on the sixth position of the cytosine, which leads to the formation of a covalent bond between the enzyme and the substrate base The formation of the cysteine–cytosine bond increases the negative ... to the methyl group of AdoMet and is the most reactive residue in the catalytic center of the enzyme To test whether the catalytic cysteine is the target for auto-methylation, we purified the ... B, the radioactive signal is increasing slowly over the course of hours with a roughly linear increase for the first h of the reaction Fitting of the FEBS Journal 278 (2011) 2055–2063 ª 2011 The...
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Báo cáo khoa học: The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors pdf
... co-transfected with the empty expression vector pCMV4 The luciferase activity for each cotransfection is represented as the fold activation compared with the activity obtained with the empty pCMV4 vector The ... factors the development of studies aimed at the identification of the biological role of Muc5b in the lung employing mouse models Results Characterization of the sequence of the promoter of the murine ... to the )1195 ⁄ )718 region of the promoter may interfere with GATA function in these cells GATA cis-elements within the promoter of Muc5b were then identified by performing EMSA experiments with...
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Walt Disney: The Mouse That Roared (Legends of Animation)
... get away with so we used to have to everything at one time And we used to have to run the cartoon We’d have the fellows with the sound effects We had the people with the voices We had the orchestra ... famed Newman Theatre, to sell the owner of the theater on buying it and making it a regular feature Walt arranged to show the 300-foot cartoon to Milton Feld, the manager of the Newman Theatre Company, ... after six weeks on the job, along with Iwerks and others Nonetheless, he considered his time there worthwhile, learning numerous “tricks of the commercial [art] business.” In the interim, Walt...
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Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot
... transfected with either construct F1R4-1 (see Fig 4A) or with the jB mutant construct F1R4-1MutjB, or were co-transfected with either the p50 or p65 overexpression plasmid TNF-a was also included in the ... The precursor p105 protein was used to represent p50 levels in the western blot Displayed below the blots are the computed relative levels of the respective protein after normalization with the ... (Table 1) Mouse EST sequences for p65 are found in the oocyte, pre-implantation embryos and in the testis On the other hand, p50 ⁄ Nf-jb1 EST sequences are found in the oocyte and in the testis...
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Báo cáo sinh học: " Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model" pdf
... either at a very low level or were below the level of detection of the assay in the non-infected control group, and the objective of the study was to evaluate the effect of motavizumab in the ... motavizumab on the cytokine and chemokine responses induced by RSV both in the respiratory tract and in the systemic compartment, which, we hypothesized, were likely associated with the observed ... the AO; in fact, mice treated with the mAb remained clinically asymptomatic throughout the experiment compared with the RSV-infected untreated mice (Figure 1) Furthermore, motavizumab administration...
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Báo cáo sinh học: " Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse" pdf
... Since the latter Abs are a fraction of the Figure Composition of MAPs Composition of MAPs The amino acid (aa) composition of the scaffolds of G39d and G40d is shown in single letter code The triple ... significantly from the control group The strongest and most significant resistance was seen in mice vaccinated with ODN and CT by the i.n route The other two vaccination groups (i.n with ODN but without ... which they recovered Four weeks later, the mice were inoculated i.n with PR8-Seq14 (200 TCID50), again with or without M2e-MAP Other groups of mice were inoculated twice by the i.n route with...
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báo cáo hóa học: " Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson''''s disease" pptx
... accordance with the mg/kg amount of valdecoxib each mouse received daily It has been suggested that the level of COX-2 in the HT mouse is half of the WT [25]; therefore, we assigned the WT as ... In sections with numerous activated microglia, the SNpc can be distinguished from the surrounding areas as the activated microglia tend to stay within the SNpc or along the border of the SNpc MPTP-induced ... activated microglia With all the data analyzed or with only the data from the MPTP-treated animals, we can see that the number of TH-stained neurons has a high positive correlation with the number of...
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Báo cáo hóa học: " Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model" potx
... either at a very low level or were below the level of detection of the assay in the non-infected control group, and the objective of the study was to evaluate the effect of motavizumab in the ... motavizumab on the cytokine and chemokine responses induced by RSV both in the respiratory tract and in the systemic compartment, which, we hypothesized, were likely associated with the observed ... the AO; in fact, mice treated with the mAb remained clinically asymptomatic throughout the experiment compared with the RSV-infected untreated mice (Figure 1) Furthermore, motavizumab administration...
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báo cáo hóa học:" Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter" pptx
... not found in the OKdb: Mrgpre, Ctla4 and Eda These are potentially important due to the fact that they are common to all three studies The StAR gene was not found in either of the other group’s ... that the mouse StAR gene is a Foxl2 target validates the approach chosen for this study The GnRHR gene was not found in either of the other group’s data sets and is noted in Table because further ... Carlsbad, CA) The repression activity of the Mad-SID is mediated through interactions of the Mad N-terminus with the mammalian Sin3 co-repressor protein [10,11] The effectiveness of the Sin3 binding...
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Department of the Army position pdf
... Forced Draft Fan with Inlet Damper Typical Outlet Fan Dampers .: Fan Curves for Different Inlet Vane Positions Fan Curve for Fan with Outlet Damper ... Non-Condensing Turbine Thermostatic Steam Trap Float and Thermostatic Steam Trap Disc/ Thermodynamic Steam Trap ... 2-32 Fire Tube Cleaning System 2-33 Fixed Position Mechanical Sootblower 2-355 Underfeed...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25