toward a mechanism of stressor induced alterations in microflora
A proteomics study of chemically induced cirrhosis in rat liver revealed the mechanism of thioacelamide hepatotoxicity 3
... same time thus providing statistically-significant spot data 93 Chapter 3.2.1 Visual analysis results Our preliminary visual analysis yielded several regions of interest that was further analyzed ... axis, and σy is the standard deviation in the direction of the y axis These data can provide quantitative data for each spot within a group of gels and thus level of up- or down-regulation can be ... non-redundant databases (*) while (b.) protein coverage was calculated based on the percentage of amino acids residues covered in a particular protein by the matched peptides (c.) Values for...
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A proteomics study of chemically induced cirrhosis in rat liver revealed the mechanism of thioacelamide hepatotoxicity 4
... release of iron, by autophagic vacuolar apparatus in macrophages during inflammation [Sakaida et al., 1990] Free iron is dangerous as it can act as a catalyst in the Fenton (Crichton et al., ... found that in vivo TAA administration to male rat had been demonstrated to inhibit δ-aminolevulinic acid (ALA) synthetase (Matsuura et al., 1983) In the same paper, Matsuura and co-workers also ... et al., 1988) Besides, ferritin was also reported as being degraded, with the release of iron, by autophagic vacuolar apparatus in macrophages during inflammation (Sakaida et al., 1990) Since...
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A proteomics study of chemically induced cirrhosis in rat liver revealed the mechanism of thioacelamide hepatotoxicity 2
... stirring with a magnetic stirrer 2.2.3 Administration of TAA TAA was administered to the rats via intraperitoneal injection Each rat was weighed before being injected with 300 mg/kg of TAA using ... food and water These rats were kept for a week for acclimatization prior to thioacetamide (TAA) administration 2.2.2 Preparation of 10% thioacetamide To prepare a 10% TAA solution, 10 g of TAA was ... The search parameters allowed for oxidation of methionine, N-terminal acetylation, carboxyamidomethylation of cysteine, and phosphorylation of serine, threonine and tyrosine Manual MS-Fit was performed...
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A proteomics study of chemically induced cirrhosis in rat liver revealed the mechanism of thioacelamide hepatotoxicity 1
... integrated approach to build, test and refine a model of a systematically perturbed yeast galactose utilization pathway were analyzed using DNA microarray, quantitative proteomics and databases of ... with a therapeutic agent in a systematic manner, thus statistically significant data can be obtained, alleviating polymorphism or artifacts arising from patient subject study alone In fact, animal ... Glycoproteins Laminin Fibronectin Entactin (nidogen) Elastin Proteoglycans Heparan sulphate Portal tract matrix, hepatic veins, points of inflection in hepatic cords Portal tract matrix, space of Disse...
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Báo cáo khoa học: A novel mechanism of TGFb-induced actin reorganization mediated by Smad proteins and Rho GTPases docx
... GCGGGTACCAATGTGATGGGTGGACTGGT GCGAAGCTTACCAGACCGTGGACTAACGA CCCACCGTCTTCGAGAACTA CTTCCTTGGTCTTGGCAGAG CCAGACTAGATGTAGTATTTTTTG ATTAGAGCCAGATGCTTAAGTCC ACCACAGTCCATGCCATCAC TCCACCACCCTGTTGCTGTA and then treated ... total actin ratio in each condition These data are representative of three independent experiments Sample G ⁄ total actin ratio Standard error ad-LacZ ad-LacZ + TGFb1 ad-Smad2 ad-Smad2 + TGFb1 ad-Smad3 ... a greater decrease in the G ⁄ total actin ratio, corresponding to a clear shift of the dynamic equilibrium towards polymerized actin Thus, quantitative analysis of actin dynamics revealed that...
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An Essay Toward a History of Shakespeare in Norway doc
... hjaa deg ho gamle Mabba, Nổrkona aat Vettom So lita som ein Adelstein i Ringen paa fremste Fingren paa ein verdug Raadsmann, ho kjứyrer kring med smaa Soldumbe-Flokar paa Nasanna aat Folk, dan ... fully and satisfactorily resolved by the appearance of Rosse." And his note to a passage in Act V is interesting as showing that, wide and thorough as was Hauge's acquaintance with Shakespearean ... Landsmaal is equal to Shakespeare's most airy passages The slight inaccuracy of one of the lines: Av Maanestraalanne paa Vatn er Selen, for Shakespeare's: The colors of the moonshine's watery beams,...
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A self organizing neural network model for a mechanism of pattern recognition unaffected by shift in position
... immediately mean that these patterns are of different categories Suppose that the upper part of the input pattern matches with that of the standard pattern situated at a certain location, and that, ... the largest output is chosen as a candidate for the representatives Hence, there is a possibility that a number of candidates appear in a single S-plane If two or more candidates appear in a single ... human brain, the process of recognizing familiar patterns such as alphabets of our native language differs from that of recognizing unfamiliar patterns such as foreign alphabets which we have...
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báo cáo khoa học: " Isolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization" doc
... Rev5'TACCTCCTGGCTTCAACCAT; P5 CSFor5'GATGTTTTTGCTGCCATTGA, Rev5' GC TAATC CC AACCTCAGCAC; DnaJ-For5'GGAATACAGGAGGGG GA CAT, Rev5'CCTTTTGGGAGAACCAAACA; BADH-For5' TGGAAAATTGCTCCAGCTCT, Rev5'CTGGACCTAATCCC GTCAAA; ... glycinebetaine synthesis even in the plants not accumulating glycinebetaine naturally, like Arabidopsis thaliana, Brassica napus and Nicotiana tobacum [98] Moreover, modelling of the labelling kinetics ... domain in AMPK has greater affinity for AMP than for ATP, and as the cellular energy content drops (low ATP, high AMP), binding of AMP to CBS domain of AMPK facilitates its phosphorylation making...
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Báo cáo y học: "A mechanism of airway injury in an epithelial model of mucociliary clearance" doc
... the palates surface The area of the palate was approximated by measuring across the lateral-most borders of the jaw at the base of the palate, and calculating the area of the equivalent half-circle ... concentration of the applied metabisulphite By approximating the area of the palate as one-half the area of a circle (~5 cm2 on average) and assuming a mucus plus periciliary layer of 10 µm, a volume ... have been shown to play a role in airway injury and remodeling [7,8] and in cellsignaling pathways [14] Materials and Methods Development of a frog palate injury model A fresh frog palate was...
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Báo cáo y học: "The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study" pdf
... (5'-GTCCCTGTTCGGGCGCCAC), D25 (5'-CTGAGACAACATCTGCTGAGGTAGG), and D26 (5'-CTGAGACAACATCTG CTGAGGTA GGA), and templates D3 6A (3'-CGAAAGTCCAGGGA CA AGCCCGCGGTG TGTATCTCT), D36C (3'-CGAAAGTC- Page of 16 (page number ... were calculated using Sigma Plot 9.0 (Systat Software, San Jose, California, USA) Drug combination data analysis Median-effect analysis The degrees of synergy and antagonism were determined using ... carried out a portion of the biochemical assays FM and DG carried out the cell-based drug combination assays KLW and ESS participated in the study design, data analysis, and manuscript preparation...
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Bóa cáo y học: " Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the event of septic shock" ppt
... Microbiological findings pointed towards a predominance of Gram-negative bacteria as responsible pathogens and towards a monomicrobial cause of VAP (Table 1) It was proved that apoptosis is a phenomenon ... Resolution of VAP was considered as any decrease of X-ray findings accompanied by an increase of the pO2/FiO2 ratio Antimicrobial therapy of VAP was selected by attending physicians according to ... Jr, Amado VM, Caserta R, Dalla Valle Martino M, Pasternak J, et al.: Ventilator associated pneumonia: comparison between quantitative and qualitative cultures of tracheal aspirates Crit Care...
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Báo cáo y học: "Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury" docx
... elucidate the mechanisms of response and nonresponse to INO in an endotoxin -induced animal lung injury model Materials and methods Animals After approval of the local Animal Research Ethical committee, ... Effect of endotoxin Endotoxin exposure caused an increase in the MPAP and the pulmonary vascular resistance, whereas the cardiac output remained unaltered There was a mean decrease in the mean arterial ... oxygenation are presented as the PaO2/FiO2 A left carotid arterial line was inserted, and a Swan–Ganz catheter was introduced into the right jugular vein The bladder was catheterized (balloon catheter...
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Báo cáo y học: "Duration of salmeterol-induced bronchodilation in mechanically ventilated chronic obstructive pulmonary disease patients: a prospective clinical study" pot
... 0) and after salmeterol administration are shown in Table The administration of 100 μg of salmeterol caused a significant decrease in dynamic and static Paws as well as in Rint, Rrs, and intrinsic ... achieved a hemoglobin saturation of greater than 89% Minute ventilation was adjusted in each individual by the attending physician in order to maintain normal arterial pH and remained constant throughout ... No Malliotakis et al Figure Figure Individual salmeterol administration inspiratory resistance (Rint) before and after patient values of minimum and after salmeterol administration Baseline values...
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Báo cáo y học: "Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury" pps
... [9,21] All data were analyzed using ANADAT data analysis software (RHT-InfoData, Inc., Montreal, Quebec, Canada) Echocardiography Volemic status and cardiac function were assessed by an echocardiograph ... Normovolemia was maintained at a MAP of about 100 mmHg Hypervolemia was obtained with colloid administration (Gelafundin®; B Braun, Melsungen, Germany) at an infusion rate of ml/kg/min to achieve a MAP ... MAP of about 130 mmHg Following that, the colloid infusion rate was reduced to ml/kg/min in order to maintain a constant MAP Depth of anesthesia was similar in all animals and a comparable amount...
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A survey on the attitude of teachers and students toward the integration of some cultural elements in the textbook New English file - elementary in speaking les
... teaching culture has been integrated into language teaching programs and teaching materials in one way or another Many educators have applied these programs into real classroom activities and ... students towards the importance of speaking skill in ELT in general, the attitudes of the informants towards speaking skill, cultural knowledge in the teaching and the learning of speaking skill, in ... culture; language is deeply embedded in a culture; language and culture cannot be separated, and we cannot teach a language without teaching a culture It means that teaching language is teaching culture...
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A metabolomics approach to understand mechanism of heat stress response in rat
... thyroxine (T4) and the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatine kinase (CK) and lactate dehydrogenase (LD) in heat stressed ... established by calculating the mean of triplicate acquisitions of each sample as well as those of replicate data sets using METDAT Data processing and data analysis was also carried out using MATLAB v 7.4.0.287, ... well as analysis of variance (ANOVA) within samples as well as within replicates of each sample Here we compare the F value at particular degrees of freedom obtained from a chi-square table at...
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Investigation of blast induced neurotrauma in a rodent models
... Overview of Traumatic Brain Injury Traumatic brain injury (TBI) is one of the foremost causes of disability and death in both civilian settings and theatres of war TBI can be simply defined as damage ... resulting in focal injuries at both sides of the brain These acceleration/deceleration forces can also cause stretching and shearing of the brain tissue when rotational forces are involved In addition, ... during task training Subjects are also generally able to master the beam walking task in a shorter time (i.e within a day), as compared to the long training period required to achieve baseline...
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Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... medium was then aspirated and replaced with DMSO The absorbance was read at 540nm in a microtiter plate reader Quantitation of internucleosomal DNA fragmentation by ELISA Internucleosomal DNA fragmentation ... to apoptosis induced by hypoxia There are two major intracellular apoptosis-signaling cascades; mitochondrial pathways and death receptor pathways [4] Mitochondrial pathways are regulated by various ... Discussion Apoptosis is a cascade of events that involves activation of many genes and synthesis of numerous proteins Upon exposure to hypoxia, an increase in internucleosomal DNA fragmentation as a result...
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Tiểu luận tiếng anh : Robinson Crusoe – A Representative of the English Bourgeoisie in the early 18th century
... sheep-raising and wood-making industries They had to join the force of cheap labor and working in such factories England became a typical example of initial accumulation of capitalism Holding power ... Although food was a major conflict in the begining of his isolation on the island, Robinson Crusoe was able to overcome it and maintain a very successful way of obtaining food Among such hardships ... his actual life: a fine place to live in, good and delicious food to eat and to drink, etc Most notable, he made a candle by saving the tallow of goats and making the wick of some oaken His creativity...
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