0

the multiprotein system of non homologous end joining

ANTI CANCER EFFECTS OF THYMOQUINONE IN BREAST CANCER CELLS INVOLVEMENT OF NON HOMOLOGOUS END JOINING AND TELOMERE TELOMERASE HOMEOSTASIS

ANTI CANCER EFFECTS OF THYMOQUINONE IN BREAST CANCER CELLS INVOLVEMENT OF NON HOMOLOGOUS END JOINING AND TELOMERE TELOMERASE HOMEOSTASIS

Tổng hợp

... polymerase-negative control The ratio between the net increase of fluorescence emission ( FL), which is derived from the telomerase-dependent synthesis of the PCR product, and the net increase of sulforhodamine ... attributed to the end replication problem of the lagging strand or in some cases due to the presence of exonucleases (Xin and Broccoli, 2004) The end replication problem arises due to the intrinsic ... Non- homologous end- joining (NHEJ) pathway is one of the major DNA DSB repair pathways in mammalian cells (Jackson, 2002; Lieber et al., 2004) NHEJ mediates the repair of DSBs by directly re-joining...
  • 114
  • 290
  • 0
DETERMINING MOLECULAR MECHANSIMS OF DNA NON-HOMOLOGOUS END JOINING PROTEINS

DETERMINING MOLECULAR MECHANSIMS OF DNA NON-HOMOLOGOUS END JOINING PROTEINS

Y dược - Sinh học

... catalyze ligation of the DNA DSB stabilizing the two DNA ends at the site of the break, forming a synaptic complex that secures the two ends together [14] The catalytic activity of DNA-PK is activated ... addition of nucleotides at the site of the break [9] Despite the term non- homologous end joining, it has been shown that there can be a greater tendency to join two broken ends that contain sequences ... for the recruitment of other proteins in the pathway This leads to the hypothesis that this protein complex could be responsible for bringing the two ends of DNA together and maintaining them...
  • 153
  • 139
  • 0
Báo cáo y học:

Báo cáo y học: "Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome" potx

Báo cáo khoa học

... approved by the Ethics Committee of the Medical Faculty of the University of Liege The investigation conforms with guidelines on laboratory animals published by the US National Institutes of Health ... compliance of the respiratory sysand static compliance of the respiratory system (Crs) conditions of the present study, but may not be warranted in the clinical setting It could be argued that the effects ... collected the data during the experiments BL and PG analysed the data and performed the statistical analysis VD participated in the design and the coordination of the study and helped to draft the...
  • 6
  • 275
  • 0
Tài liệu THE MATHEMATICAL THEORY OF NON-UNIFORM GASES pptx

Tài liệu THE MATHEMATICAL THEORY OF NON-UNIFORM GASES pptx

Kế toán - Kiểm toán

... many years Rather the ideas of kinetic theory found their way into other fields, such as radiative transfer, the theory of ionized gases, the theory of neutron transport and the study of quantum ... extension of the molecular hypothesis is the theory (called the kinetic theory of heat) that the molecules move more or less rapidly, the hotter or colder the body of which they form part; and that the ... The kinetic theory of heat (i)—3 The three states of matter (i)—4 The theory of gases (2)—5 Statistical mechanics (3)—6 The interpretation of kinetic-theory results (6)—7 The interpretation of...
  • 448
  • 1,051
  • 0
Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Báo cáo khoa học

... into the chitinolytic potential of L lactis, the present results provide only the third example of the role of family 33 CBPs in the degradation of recalcitrant polysaccharides Furthermore, the ... drawn for ChiC1 from S marcescens The fact that the longer part of the substrate extends towards the + side of the catalytic centre is compatible with the notion that the C-terminal substrate-binding ... presence of LlCBP33A In the absence of LlCBP33A, the end- point of the reaction (i.e solubilization of all chitin) was reached after approximately weeks When LlCBP33A was present in the reaction, the...
  • 14
  • 683
  • 0
Tài liệu The Total Cost of (Non) Ownership of a NoSQL Database Cloud Service ppt

Tài liệu The Total Cost of (Non) Ownership of a NoSQL Database Cloud Service ppt

Cơ sở dữ liệu

... during offpeak hours At the end of the month, the game accumulated approximately 1,200 GB of data For the next several months, the game was experiencing uniform traffic similar to that of Month ... the traffic subsided, and the demand decreased for the game Reads and writes dropped to 2,000 per second during peak hours and 1000 per second during off-peak hours At the end of the month, the ... from the headaches of provisioning hardware and systems software, setting up and configuring a distributed database cluster, and managing Page of 14 Amazon Web Services – The Total of (Non) Ownership...
  • 14
  • 602
  • 1
Tài liệu From Burden to “Best Buys”: Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income Countries pdf

Tài liệu From Burden to “Best Buys”: Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income Countries pdf

Cao đẳng - Đại học

... incurred as a result of its use The designations employed and the presentation of the material in this overview not imply the expression of any opinion whatsoever on the part of the World Health ... on The Global Economic Burden of Non- communicable Diseases – Prepared by the World Economic Forum and the Harvard School of Public Health (2011) Source: Based on The Global Economic Burden of Non- communicable ... on The Global Economic Burden of Non- communicable Diseases – Prepared by the World Economic Forum and the Harvard School of Public Health (2011) Source: Based on The Global Economic Burden of Non- communicable...
  • 12
  • 799
  • 1
The cooling system of car

The cooling system of car

Cơ khí - Chế tạo máy

... with the engine running In the past, the fan was attached to the engine and was driven by the fan belt The speed of the fan was directly proportional to the speed of the engine This type of system ... for the width of the unit When the car was in motion, the speed of the air entering the grill was sufficient to keep the coolant at the proper temperature, so the fans were shut off When the ... maintenance of the cooling system is very important to the life of the engine and the trouble free operation of the cooling system in general The most important maintenance item is to flush and refill the...
  • 9
  • 609
  • 0
Đề tài

Đề tài " The L-class of non-Witt spaces " pot

Thạc sĩ - Cao học

... L-classes of self-dual sheaves from [CS91] and state and prove the main theorem of this paper on the L-class of non- Witt spaces (Theorem 5.2) We conclude with an illustration of our results for the ... visible L-theory whose image under assembly is the symmetric signature Moreover, the Pontrjagin character of the associated K-homology class equals the L-class of the self-dual sheaf The latter ... unpublished work of J Morgan on the characteristic variety theorem From the point of view of characteristic classes, the question arises: Do different choices yield the same L-classes? In the present...
  • 25
  • 498
  • 0
PROTOCOL ON THE STATUTE OF THE EUROPEAN SYSTEM OF CENTRAL BANKS AND OF THE EUROPEAN CENTRAL BANK pdf

PROTOCOL ON THE STATUTE OF THE EUROPEAN SYSTEM OF CENTRAL BANKS AND OF THE EUROPEAN CENTRAL BANK pdf

Ngân hàng - Tín dụng

... months of the publication of the decision or of its notification to the plaintiff or, in the absence thereof, of the day on which it came to the knowledge of the latter, as the case may be 14.3 The ... 17 of the Act concerning the conditions of Accession of the Czech Republic, the Republic of Estonia, the Republic of Cyprus, the Republic of Latvia, the Republic of Lithuania, the Republic of ... equal to the sum of: — 50% of the share of its respective Member State in the population of the Community in the penultimate year preceding the establishment of the ESCB; — 50% of the share of its...
  • 14
  • 1,013
  • 0
Báo cáo khoa học: Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons ppt

Báo cáo khoa học: Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons ppt

Báo cáo khoa học

... and C mawsoni) However, the lack of a clear relationship with the Hb sequences of other nototheniid species suggests that in this case the evolution of the oxygen-transport system has occurred in ... species of the family Nototheniidae have one major and one minor Hb (Hb and Hb 2, 95% and 5% of the total, respectively) [2, 4,14] The two Hbs have the b-chain in common, with the exception of those ... cancels the contribution of the N-terminus to the Bohr effect These substitutions are also found in the two Hbs of G gibberifrons, characterized by the Bohr and Root effects However, these Hbs...
  • 7
  • 417
  • 0
Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx

Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx

Báo cáo khoa học

... complementation of the glucose-specific PTS of E coli measuring phosphoenolpyruvate-dependent phosphorylation of methyl [a-14C]glucoside ([14C]aMG; Amersham) in the presence of E coli LM1 cell extract [16] The ... Analysis of the Fig Genetic organization of the S coelicolor crr gene and protein alignment (A) The genetic arrangement of the crr and ptsI gene is shown Arrows indicate transcriptional orientation of ... regulate the function of some of the > 140 MalK homologues found in the S coelicolor genome The one with the highest similarity of 46% identical amino acids is MsiK, which serves as the ATPase subunit...
  • 8
  • 564
  • 0
The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years pptx

The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years pptx

Sức khỏe trẻ em

... years The two deaths recorded were both nonliver related, and none of these two cases had liver biopsy performed at any time DISCUSSION The study is the first to describe the long-term survival of ... components in the development of NAFLD.42 The main strengths of our study are the inclusion of children with the whole spectrum of NAFLD from simple steatosis to cirrhosis along with the long-term ... although CT or MRI may show the presence of pelvic soft tissue mass The mainstay of treatment for actinomycosis remains antibiotics in the form of penicillins and removal of the IUCD.5 Gut 2009;58:1544...
  • 7
  • 487
  • 0
Báo cáo

Báo cáo "Monte carlo simulation by code of MCNP and experimental check for measuring thickness of materials for the specializing system of MYO-101 " ppt

Báo cáo khoa học

... / VNU Journal of Science, Mathematics - Physics 26 (2010) 43-49 includes two parts: i) the theoretical simulation of measuring intensity for thickness of materials by the system of MYO-101 with ... of Science, Mathematics - Physics 26 (2010) 43-49 47 Proccessing of the measured results and drawing of graphs are done by software of Origin The fitted equations and saturation thicknesses of ... comparison of the results calculated by MCNP and measured experimentally, it could be seen the advantage of MCNP program for simulating backscattering effect of gamma-ray in the case of the dedicated system...
  • 7
  • 467
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "ON THE LINGUISTIC CHARACTER OF NON-STANDARD INPUT" ppt

Báo cáo khoa học

... NV, the most notable being sentences with dummy there subjects Thus, the first of the sentences in (i) is the more likely in NV while, of course, only the second can occur in SWE: (I) a There ... prerequisite to the development of truly robust systems The final sort of non- standard input that we will mention is the uncorrected true error In our analysis of 40 or more hours of spoken interview ... is given in (8), where the object of a prepositional phrase turns into the subject of a following clause: (8) When I was able to understand the explanation of the moves of the chessmen started...
  • 3
  • 284
  • 0
THE EUROPEAN CENTRAL BANK THE EUROSYSTEM - THE EUROPEAN SYSTEM OF CENTRAL BANKS potx

THE EUROPEAN CENTRAL BANK THE EUROSYSTEM - THE EUROPEAN SYSTEM OF CENTRAL BANKS potx

Ngân hàng - Tín dụng

... minimum term of office for NCB governors of five years; • a non- renewable term of office of eight years for members of the Executive Board of the ECB; • removal of the Members of the Executive ... Board of the ECB and the governors of the NCBs of the euro area countries .The Statute of the ESCB states that the Governing Council of the ECB must meet at least ten times a year .The dates of its ... of the NCBs in the performance of their tasks Personal independence The Statute of the ESCB and of the ECB provides for security of tenure for governors of NCBs and members of the Executive Board...
  • 36
  • 367
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "THE TEXTUAL DEVELOPMENT OF NON-STEREOTYPIC CONCEPTS" potx

Báo cáo khoa học

... on the concepts of the background knowledge A discourse state is defined by the actual state of all the five layers of the text representation, which renders the actual state of the view and the ... control of operations on the knowledge base and on the view, because the manipulations of the lower layers depend on the interpretation of the upper layer phenomena We define the types of manipulations ... distinguishing the mechanisms involved in terms of the textual function of linguistic means with respect to the different layers of the text representation In our model the units of the layer of thematic...
  • 6
  • 227
  • 0
Báo cáo hóa học:

Báo cáo hóa học: " Optimal Detector for Multiplicative Watermarks Embedded in the DFT Domain of Non-White Signals" pptx

Báo cáo khoa học

... cos 2(πk/N) + a2 + + a4 The proof of the above equations is given in the appendices In Figure 2, the theoretical variances and experimental of real and imaginary parts of the DFT coefficients are ... (hypothesis (H0b )) The events (H0a ), (H0b ) are mutually exclusive and their union produces the hypothesis (H0 ) The performance of a watermarking method depends mainly on the selection of the watermark ... deals with the statistical analysis of the behavior of a blind robust watermarking system based on onedimensional pseudorandom signals embedded in the magnitude of the Fourier transform of the data...
  • 11
  • 216
  • 0
Báo cáo nghiên cứu khoa học:

Báo cáo nghiên cứu khoa học: "Monte carlo simulation by code of MCNP and experimental check for measuring thickness of materials for the specializing system of MYO-101" pptx

Báo cáo khoa học

... / VNU Journal of Science, Mathematics - Physics 26 (2010) 43-49 includes two parts: i) the theoretical simulation of measuring intensity for thickness of materials by the system of MYO-101 with ... of Science, Mathematics - Physics 26 (2010) 43-49 47 Proccessing of the measured results and drawing of graphs are done by software of Origin The fitted equations and saturation thicknesses of ... comparison of the results calculated by MCNP and measured experimentally, it could be seen the advantage of MCNP program for simulating backscattering effect of gamma-ray in the case of the dedicated system...
  • 7
  • 487
  • 0

Xem thêm