the iap family of proteins and their regulators
Báo cáo khoa học: The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs pdf
... above the relevant lanes, and the absence of any added protein is indicated by ()) The position of the free RNA and of the loading slots is indicated to the right of each gel A B abolished by the ... series of GFP fusions with the various motifs of Roquin, and by selectively deleting domains from the full-length protein, we determined that the ROQ domain in the N-terminus of the protein is the ... indicate this On the left side of the gel, bands in the Icos mRNA probe ladder are aligned to the Icos target RNA (B) Nucleotide sequence of Icos-specific RNA used in the REMSA (Fig 6) and RNase footprinting...
- 19
- 542
- 0
Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
... and drugs The therapeutic application of sHSPs is further suggested by study of other molecular chaperones, with disruption of HSPs that protect deregulated intracellular signaling proteins and ... Siddique M & Vierling E (2001) The expanding family of Arabidopsis thaliana small heat stress proteins and a new family of proteins containing a-crystallin domains (Acd proteins) Cell Stress Chaperones ... heat shock proteins and disease Therapeutic implications of sHSPs and other molecular chaperones Temperature induced synthesis of sHSPs protects against ischemia ⁄ reperfusion damage to the heart,...
- 15
- 573
- 0
Báo cáo khoa học: A structural overview of the PDI family of proteins docx
... assembly and activity of the complex is further enhanced by the addition of a and b domains [50] Mutagenesis of individual residues in PDI confirmed the importance of the a and a¢ domains in the assembly ... Leu508 of the x-linker and residues Phe484, Phe499 and Phe503 of the b¢ domain Towards the middle of the x-linker, Tyr364 of ERp57 (and Val511 of ERp72) fit into a small hydrophobic pocket below the ... conformations in the structures of the isolated b¢ domain and full-length proteins In the crystal structure of the b¢x fragment of human PDI, the C-terminal part of the x-linker turns back to contact the...
- 13
- 483
- 0
the competitive advantage of firms and their proximity to export finance centers
... which they would like to 31 assist their customer in obtaining financing and in may cases they gather most of the details of their customers financial strength and of the transaction for the lender ... and the lender must approve of the fiscal strength of the borrower and the foreign buyers in order for the guarantee to be put in place There is no maximum limit to these loans and the term of ... Bank transactions in 2005, the name and address of the exporter, contact name, the size of the credit facility, the country the export was destined for, and the type of transaction This information...
- 120
- 360
- 0
The chemical components of detergents and their roles in the washing process
... fabrics and on the washing machine’s heating elements - stabilise alkalinity at the correct level throughout the washing process thus giving good soil removal and enabling the other components of the ... number of “ new” chemicals as well as necessitating a complete change and reinforcement of other elements of the formulation The formulation of phosphate-free detergents After 30 years of research ... restructuring on the detergent's formula, often with significant increase in other existing ingredients For each of these chemicals, there are a number of environmental uncertainties or other disadvantages...
- 5
- 482
- 0
báo cáo khoa học: "Self-assembly of proteins and their nucleic acids" docx
... to the nitrocellulose which was then shaken periodically over 10' before the eluate was removed and then neutralised by the addition of 13 ul M NaOH 10 ul of the eluate, the final wash and the ... was amplified using ul of 16 pmol/ul M13F primer (part of the TOPO vector, upstream of the T7-F primer of the SAPV insert), 0.5 ul of 100 pmol/ul SA-11R primer and 0.5 ul of the untagged SAPV DNA ... synthesis will continue after the missing tRNAs are added to the translation reaction This could allow a user to manipulate the speed of synthesis and folding of the nascent protein chains and...
- 16
- 307
- 0
Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf
... parasites of the genus Giardia are one of the earliest lineages of eukaryotic cells, and the Giardia protease is the earliest known branch of the cathepsin B family [23] Its phylogeny confirms that the ... Isoelectric focusing of rPhl p N and rPhl p Q, as detected by mAb IG12 The pH values of the respective fractions and the size of the protein markers used are indicated (A) The full-length allergen ... explore the biochemical function of group I allergens Expression of glycosylated and nonglycosylated rPhl p reveals differing stability of these allergens The expression of rPhl p in the yeast...
- 10
- 535
- 0
Báo cáo y học: "Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis" pdf
... expression and protein levels of the MMPs are often found to be accompanied by increases in the levels of one or more of the TIMPs It is therefore not obvious what can be the net result of these opposing ... complicated by the many levels of regulation of proteinase activity Also, there is an emerging appreciation of considerable functional divergence of both MMPs and their regulators, particularly the tissue ... regulation of MMP activity has led to the hypothesis that shifts in the balance between these two families of proteins could distort the kinetics of membrane turnover and cause pathological changes...
- 8
- 493
- 0
báo cáo khoa học: " The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localization" potx
... for the recruitment of Nanos (Nos) and Brain Tumor (Brat) proteins to repress the translation of hunchback mRNA in the posterior region of the embryo The RNA binding domain of Puf proteins (the ... Page of 19 Figure Models of the plant PUM-HD bound to RNA (A, B) Ribbon (left) and stick (right) models of the PUM-HDs of AtPUM2 (A) and Os01g62650 (B) bound to the RNA bases of Box of the NRE ... determine the binding affinity of the AtPum2 PUM-HD to the wildtype and mutant NRE1 The AtPum2 PUM-HD Figure Models of the AtPum13 PUM-HD bound to RNA Ribbon (A) and stick (B) models of the PUM-HD of...
- 19
- 342
- 0
A study of some linguistic features of expressions describing the villains in kiều story and their english translational equivalents
... only in the Story of Ki u and their Data are analyzed on the basis of the knowledge of lexicology equivalents in the English translational versions by means of lexical and semantics These domains ... the research in the library and other sources from the Internet in both English and Vietnamese • Analyzing the lexical and semantic features of EDVs in Ki u’s Story and their equivalents in the ... CHAPTER CONCLUSIONS AND IMPLICATIONS 5.1 SUMMARY OF THE FINDINGS With the aim of studying the EDVs in the masterpiece of Nguy n Du in terms of lexical and semantic means and their English translational...
- 13
- 833
- 2
Tài liệu Project (written version):“The problems of the “Citibus” (bus operating company) and their possible solutions. Drawing a contract.” doc
... and consequently they not their best, other thing which should be mentioned is the wrong schedule of the bus routes (which doesn’t take a proper account of the interests of the passengers); and ... change the cituation for better (increase the passing capacity of the roads that doesn’t cope with the growing number of cars and other carriers, build new roads and rearrange the traffic within the ... comfortanle during the trip So the documents we offer you are the special colred tickets The second way of increasing the motivation of our drivers is to organize the competition among the drivers,...
- 5
- 682
- 0
Báo cáo khoa học: Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking potx
... cuticular proteins [35,36] The abundance of His residues in the basic QH proteins therefore raises the possibility that these proteins play an important role in maintenance of the integrity of the ... acidic S37 and other known proteins The members of basic Y and G, and acidic S37 all contain the extended R & R motif commonly found in insect cuticular proteins (Fig 2) The motif found in the horseshoe ... the N-terminal sequences of all basic Y proteins (basic Y6 through Y9), and repeats of the di- and tri-peptide sequences QQ and QQQ were observed in the amino terminal sequences of basic QH proteins...
- 13
- 582
- 0
Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... 7A–C) Therefore, the deletion of BACE1, and consequently the loss of BACE1 processing of APP, APLP1 and APLP2, had no detrimental effect on the de novo production of ICDs (compare lanes and and ... expressed, and its subcellular localization and dimerization properties are different from those of APP and APLP2 [16] Given the similarities between processing of Notch and of the APP family of proteins, ... together with associated proteins, are released from the membrane [49] Here we investigated the effects of genetic manipulation of BACE1 on the processing of APP, APLP1 and APLP2, and on the...
- 16
- 549
- 0
Báo cáo khoa học: Identification of a copper-repressible C-type heme protein of Methylococcus capsulatus (Bath) A member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins docx
... Detection of C-type heme Because of the sequence similarity of SACCP to members of the BCCP family of proteins and the prediction of heme-binding motifs in the primary sequence, it was of interest ... Both these proteins are members of the BCCP family of proteins [13] (pfam 03150), but are representatives of two functionally distinct subsets of the BCCP family [14] To further explore the relationship ... located in the core of the CCP structure (Fig 3A) Furthermore, all of the additional insertions of the extended MCA2590 sequence are introduced in loop regions on the surface of the structure, thereby...
- 12
- 392
- 0
A BRIEF HISTORY OF PANICS AND THEIR PERIODICAL OCCURRENCE IN THE UNITED STATES pdf
... while the demand for what the farmers had to sell fell away, and bills could not be met, and their troubles were added to those of the minority of the consumers of the country; the volume of business ... expect the enactment of laws to raise the price of farm products, and to lower the price of all that the farmer has to buy But the farmers vote as the manufacturers and other active classes of the ... from the standing of the banks at the first of the year, while the panics generally occurred later in the year: the last two, for instance in the second and fourth quarter, respectively The third...
- 172
- 499
- 0
Free Movement of Goods and Their Use – What Is the Use of It? pptx
... transferred to the Grand Chamber of the ECJ.55 When the oral procedure was re-opened, the Grand Chamber asked the parties and all the other Member States to give their views on: [T]he question of the extent ... the light of the Treaty rules rather than to remove them from the scope of the Treaty.79 In the light of these three reasons, he concluded that the Keck criteria were inappropriate and that the ... both for the driver of the vehicle and for other vehicles on the road, because the stability of the combination and its braking capacity would be affected.”138 The Grand Chamber of the ECJ had,...
- 42
- 760
- 0
Novel methods (sonochemistry, microwave dielectric heating, sonoelectrochemistry and RAPET for the fabrication of nanomaterials and their applications
... in our laboratory for the last four years We will show that the RAPET of silanes is yielding the smallest reported SiC particles having the highest surface area The RAPET of empty Coca Cola bottles ... The main parameters that determine the particle size in sonoelectrochemistry are temperature, sonication intensity, and the electric pulse width Its main synthetic advantage is the ability ... ability to reduce metals for which there is no reducing agent that can it For example, preparing metallic Mg nanoparticles .The last technique was named by us RAPET It stands for Reaction under Autogenic...
- 2
- 526
- 1
báo cáo hóa học:" Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma" docx
... western blot analysis in such pairs Further, we attempted to address the correlation among their expression and the relationship between their expression and the clinical parameters, including overall ... increase in the expression of p53, p21/WAF1, and MDM2 in HCC tissues than the corresponding adjacent hepatic tissues; the expression levels of the proteins in the former was 70.7%, 33.1%, and 52.5%, ... ≥10% of the tumor cells expressed p53, while in others, this cutoff value was defined as ≥5% of the tumor cells being positive for p53; further, the majority of studies have not defined the lower...
- 8
- 611
- 0
Báo cáo y học: " Change in quality of life and their predictors in the long-term follow-up after group cognitive behavioral therapy for social anxiety disorder: a prospective cohort study" pptx
... explanation of the objectives and procedures of the present study The study protocol was approved by the Ethics Committee of the Nagoya City University Graduate School of Medical Sciences Treatment The ... statistically significant changes in the domains of the SF-36 or to detect potential baseline predictors of the SF-36 at the follow-ups Nevertheless, the changes of each of the SAD symptomatology scores ... conceived of the study, performed the clinical investigation (diagnosis, treatment and assessment), and drafted the manuscript TAF participated in the design of the study and performed the clinical...
- 10
- 388
- 0
báo cáo khoa học: " Survey of smokers'''' reasons for not switching to safer sources of nicotine and their willingness to do so in the future" pdf
... nicotine products and their willingness to consider the hypothetical products Tests of statistical significance were not presented because these are only appropriate when the purpose of a study is ... on these habits On the other hand, the wide variety of low-risk products offer many options, and people often find it much easier to become used to a new ritual or habit than they think This survey ... after the product rollout due to delays by the university health research ethics board which approved the study However, limited marketing preceded the survey and there was limited awareness of the...
- 8
- 361
- 0
Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25