... cause of everything social Historical materialism is not a theory of all social phenomena, but only of a speci®c set of explananda ± the historical trajectory of economic structures and their ... human history as such In practice, then, to be ``historical'' has generally come to mean ` `to be historically speci®c,'' rather than ` `to be embedded in a theory of history.''6 As a result, the debate ... accepts this way of understanding the explanatory project of class analysis, then the central task is to sort out for speci®c explananda the forms ofinteraction between class and gender as causal...
... [23] The naked capsids then enter into the Golgi secretory pathway and are enveloped via binding tothe cytoplasmic membrane, leading to exocytosis and egress ofthe whole assembled virus from the ... with the cytoplasmic membrane [26] In this context, the efficiency and rate of viral capsid enveloping are likely to contribute tothe control ofthe efficiency and rate of viral replication The ... studies, others suggest another model that presumes the redundancy ofthe second enveloping by deducing that the viral capsids are directly transported tothe Golgi secretory pathway and out of the...
... into the conceptual design ofthe study and helped to draft the manuscript, IJ provided experimental data and data interpretation for the study, and ANE conceived ofthe study and designed and ... protein binding of three compounds and their glucuronides, the unbound fraction ofthe glucuronide increased by factors of 2.2, 1.3 and 2.6 [39] For the purposes ofthe present study, the fraction ... values for the hydroxylation, normalized tothe mean There is no correlation between the CYP3A5 genotype andthe affinity of MDZ to CYP3A (Km) or the rate of hydroxylation (Vmax) in the basal...
... sequence of ΔBAR domain of EEN Green letters stands for the SH3 domain; Black letters stands for the random coil domain The ΔBar domain which consists ofthe SH3 domain andthe random coil to determine ... Vector Design To minimize the size ofthe vector, pET-32a (+) (maps and sequence landmarks were shown in figure3.1 and table3.1) was truncated to fit for the requirement The truncated vector ... the dimer by the FPLC because ofthe large molecular weight (Figure 4.1.3) In further, these polymers may accelerate the process ofthe EEN aggregation Therefore preventing the formation of the...
... development, andthe conclusion The introduction - gives rationale for the study and sets up the aims, scopes and methods ofthe study The develoment - which is considered as the main part ofthe study, ... teachers to improve the situation of teaching and learning speaking English tothe year non-major English students would be made The thesis consists of three main parts: the introduction, the development, ... level of Proficiency at Hanoi University of Industry” is submitted in partial fulfillment ofthe requirements for the degree of Master of Arts is the result of my own work, except where otherwise...
... half the time 26% had also had women partners in the previous year, and condoms were used in only 23% of occasions of vaginal intercourse.39 As the scale ofthe pandemic increases and responses to ... women and prescribing HAART, obstetricians must always bear in mind their dual responsibility to provide optimal care tothe mother and reduce the likelihood of MTCT of HIV ‘ The core goal of all ... consisted of project-specific support for training and drugs, rather than broader programmatic development Further, the question of where to situate STI services andto whom to provide them was...
... regardless of whether zinc or cadmium is bound to them and also regardless ofthe existence ofthe second domain The assigned peaks ofthe a-domain were integrated and their consistency with the published ... the NOESY and TOCSY (not shown) spectra ofthe two domains permitted the full sequence-specific assignments, the identification ofthe spin systems andthe assignment of 398 and 252 ofthe NOESY ... concentration of mm each and incubated for >48 h before the measurement of their 1H NMR spectra The observed NOESY and TOCSY spectra (not shown) consisted ofthe sum ofthe respective spectra ofthe single...
... PLX4032 As part ofthe eligibility requirements ofthe trial, paraffin-embedded tissue from a biopsy of a cutaneous lesion was tested and shown to be positive for the BRAF V600E mutation The patient ... Rubinstein et al.: Incidence ofthe V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic responsetothe specific BRAF inhibitor PLX4032 Journal of Translational Medicine ... melanomas carrying NRAS Q61L mutations These paradoxical effects highlight the importance of tailoring treatment tothe specific genetic composition ofthe tumor [5] One of our patients with locally advanced...
... contribution tothe mediator, (3) the mediator should make a significant contribution tothe outcome, and (4) when the influence ofthe mediator is held constant, the contribution ofthe independent ... representative of those in the organization Moreover, we compared the job and demographic profiles ofthe participants to those of all employees in the organizations and found that they were very ... questionnaire A total of 265 employees (85, 101, and 79 from organizations A, B, and C) ofthe 302 employees contacted agreed to participate, for a response rate of 88 percent Ninety-seven percent of the...
... is the species with the smallest seeds, and is the most sensitive to seed age andthe effects of fire Ofthe two species of pine studied, P pinaster is the least sensitive to seed age andthe ... between the three species may explain their different behaviour during the process of germination, and their differing sensibility to high temperatures, ash, andthe effect of both of these together ... ofthe most important effects of forest fires The degree that their responsetothe effects of fire may be influenced by the age ofthe seed was also considered to be of interest MATERIALS AND...
... [29-32] The aim ofthe present study was therefore to reveal the role of c-Myc in mitogenic responseto TGF1 in nucleus pulposus cells The study was designed to (1) analyze the effect of TGF1 ... protein itself and also downregulated the phosphorylation (activation) of ERK1/2 The results of these blot analyses reveal that the effect ofthe TGF1 signal can be mitogenic when c-Myc and phosphoERK1/2 ... reported to be growth arrested by TGF1 [1], these results suggest that cMyc mRNA expression correlates with the mitogenic responseofthe cells to TGF1 stimulation To investigate the effects of c-Myc...
... an imbalance of vasodilators and vasoconstrictors or impaired sensitivity to vasoactive mediators is the cause ofthe low oxygenation Further investigation into the cause of this early deterioration ... macrophage inflammatory protein (MIP)-2 is one of its functional homologs [13] In sepsis, the development of acute lung injury may be secondary to activation ofthe inflammatory response Endotoxin administration ... added tothe RNA pellet Again, the sample was centrifuged, the supernatant discarded, andthe RNA pellet was placed in DEPC water The sample was stored at 20°C until analysis Aliquots ofthe total...
... Acknowledgements The authors thank all the subjects and doctors for their cooperation in the study Authors’ contributions SA and MI conceived ofthe study participated in its design and coordination and gave ... review of its use in the management of chronic hepatitis C monoinfection Drugs 2008, 68:1273-1317 Shiratori Y, Kato N, Yokosuka O, Imazeki F, Hashimoto E, Hayashi N: Predictors ofthe efficacy of ... alpha, other factors might also be involved in establishing theresponse rates to anti-viral treatment Additional investigations should be carried out for through comprehension ofthe study of these...
... other protocols [4]) we made an estimate of oxygen consumption from the speed and slope ofthe treadmill andthe weight ofthe subject protocols and assumed a ventilatory equivalent of 27L of ventilation ... is Chief ofthe Division of Allergy/Immunology and Director ofthe Asthma Clinical Research Center at the University of California Competing interests SDA is the inventor ofthe mannitol test ... tests The reproducibility ofthe exercise response in relation tothe different NAEPPII scores is given in Table There was no relationship between the NAEPII score andthe severity ofthe response...
... demonstrate the presence of an immune response in about 80% ofthe mares to actinobacilli normally present in the oral flora, andthe transfer of this responseto about 60% of their newborn foals The ... virulence ofthe various bacterial strains Other aspects ofthe equine neonatal immune system are also of great interest in the study of this disease Conclusion An immune responsetothe majority of ... ofthe AGID test The presence in the mare sera of antibodies to some Actinobacillus strains indicates that these strains were a persistent part ofthe oral flora ofthe horses in question The...
... the type ofand severity of trauma according to a system of points based on injuryto six regions ofthe body [10] The ISS is defined as "the sum ofthe square ofthe highest points in each of ... complications with the data of previous studies, we calculated a cutoff value for the diagnosis of sepsis Contrary tothe previous studies, however, this cutoff value only indicates the risk for the development ... point Nevertheless, PCT with a cutoff value of 1.5 ng/ml had a specificity of 70% for the diagnosis of sepsis in this study These data were similar tothe results of PCT measurements of a study...
... in the test In this part ofthe test, participants listened and read a short conversation, then they had to decide the intonation contours ofthe underlined sentences by clicking to one ofthe ... WASP and Online Audio Recorder to improve students’ sentence intonation in terms of perception and reproduction • Confirm the easiness ofthe two open-access tools tothe learning of intonation and ... consists of chapters: Chapter 1: Literature Review gives the theoretical background to Intonation and Intonation teaching as well as reviews the previous studies related tothe research area ofthe thesis...
... called the photon The operator N ẳ aya is called the h photon number operator, since it gives the number of energy units, i.e., the number of photons The amplitude operators a and ay, are called the ... 2.2.1 INTERACTIONS OF ELECTRONS AND PHOTONS Hamiltonian for the PhotonElectron System andthe Equation of Motion The Hamiltonian for the optical energy is obtained by taking the summation ofthe ... Hp, and Hi are the Hamiltonians ofthe electron, ofthe field energy, andoftheinteraction energy, respectively, and H0 describes a Hamiltonian for total energy under an assumption that there...