... licentiate thesis ofthe present kind is reminiscent ofthe storybook form The aim is not to provide a synthesis; rather, it provides a multitude of pictures of processes and activities The present thesis ... sites of their production and use’.85 As informatics shifts from the study of information systems to the study ofdesignof services, 86 and networks of information and communication, design ... responsibility for and participation in the Public Internet Monitor Project thedesignofthe gateway as well as the physical designand placement ofthe monitors Among the questions raised during the evaluation...
... evidence ofthe efficacy ofthe communication capabilities ofthe Web in facilitating knowledge construction and attitude change in the area of health education The Faculty of Education at the University ... understanding ofthe perceived effectiveness ofthe learning environment from the student and lecturer perspective The analysis of this data is expected to provide a fuller understanding of: the ... learning activity The student also has the opportunity to view their responses andthe responses ofthe other members in their group to the initial, topical questions by accessing the ‘Individual...
... Assessment ofthe Content, Design, and Dissemination ofthe Real Warriors Campaign Identify the strengths ofthe design, content, and dissemination strategies used by the RWC and which aspects ofthe ... Staff, the Unified Combatant Commands, the Navy, the Marine Corps, the defense agencies, andthe defense Intelligence Community iii iv Assessment ofthe Content, Design, and Dissemination ofthe ... dissemination ofthe content These activities were designed by the RWC staff to influence the four constructs in xiv Assessment ofthe Content, Design, and Dissemination ofthe Real Warriors Campaign the...
... on the basis ofthe volume of output produced Andthe outcome and productivity ofthe workforce will be varied according to their satisfaction with the company policies and procedures If the ... recruitment andthe promotion The promotion is the move ofthe staff when the company initiates the whole process The real internal recruitment is than a move ofthe employee initiated by the employee ... offered to ensure the mutual benefit ofthe staff and also the company Then in order to have qualified staff, the company needs to know well their capability, expectation and requirement of the...
... ofthe roof at centerline of tank Eaves—highest level at which the tank diameter is maximum; or the 70-deg point ofthe roof slope of curved or conical roofs, if present The 70-deg point is the ... between and ft (2.1 and 2.4 m) above the base ofthe ladder and should extend a minimum of 48 in (1.2 m) above the offset landing platform A5.4.5 and A5.4.6 Steel tank roof openings and floor ... reinforcement and structural steel The codes and standards to which thedesign conforms, the tank capacity, andthedesign basis or loads used in design should also be shown 1.3.2 Design Basis...
... The development of computational tools capable of predicting the specificity of RNA-binding proteins across entire families (such as the RRM superfamily), or of redesigning the specificity of these ... on the presence or absence of a cytosine at position )5 in the RNA A likely explanation for the importance ofthe )5 cytosine mutation is offered by the observation that the amino group ofthe ... are located in a double-stranded region of RNA, and not interact with the protein [54], yet the disruption ofthe helix clearly affects the binding energy The effect of these changes in RNA conformation...
... constant value of Hz for the H1 signal ofthe GlcNAc residue andthe NMR chemical shifts of H5 and C5 ofthe rhamnose residues showed that the former is b-linked andthe latter are a-linked The NOESY ... the major O repeat ofthe OPS has structure 2: each other in the position of substitution of one ofthe rhamnose residues (RhaIV) in the main chain andthe site of attachment ofthe GlcNAc side ... either the LPS core structure or /and in the mode ofthe attachment ofthe OPS to the core Therefore, strains of pathovar porri are clearly distinct from other P syringae pathovars in serology of...
... testimony to the ingenuity ofthe early designers ofthe Internet architecture, andthe fact that by and large, their original design has been maintained and has guided the development ofthe network ... these and other questions have motivated the development of a theory ofthe Internet that is firmly based on some ofthe general principles reported in this paper and derived from a study ofthe ... development of such a theoretical foundation for the Internet and other complex systems is the topic ofthe companion article [16] Complexity and designed-for robustness in the Internet Taking the initial...
... into the pH dependence of their NMR parameters over the pH range 3–8 Obviously, the pH titration curve ofthe amide proton andthe titration curve of 31P of phosphorylated serine residue have the ... pKa1 and pKa2 The pKa value is determined from a fit ofthe phosphorus chemical shifts ofthe without ionic, monoionic and diionic forms ofthe phosphate group as a function of pH [33,34] The phosphorus ... neutral pH, affects the electrostatic potential and quite often the conformation ofthe modified protein Even in the absence of rearrangement, the change in the electric field and steric hindrance...
... The results are presented in Fig In the absence of ligand, none ofthe AR NTD proteins showed LBD interaction However, in the presence of ligand, both AR.NTDwt and AR.NTDD3– 13 bound to AR LBD with ... interaction with the charged clamp [5,36,37] The first and last leucine residue in the LxxLL motif enter the hydrophobic cleft in the LBD, and directly contact amino acid residues within the cleft The variable ... control Substitution of V30 and V33 partially reduced the interaction, whereas the F23R,F27R mutation completely abolished the interaction (Fig 6A) Expression levels of GalADAR.NTDwt and GalAD-AR.NTD30/33RR...
... comparison of its MS with that ofthe reference compound The absolute configuration of glycoses was established by capillary GLC of their acetylated (-)-2-butyl glycosides, according to the method of ... stainless steel needle (27 g) was butted against the low dead volume tee and enabled the delivery ofthe sheath solution to the end ofthe capillary column The separations were obtained on 90-cm long ... 2-acetamido-2-deoxy-D-galacturonic acid The sequence of constituent glycoses andthe location of L-Ala were confirmed by 2D NMR analysis performed on both CPS and aqueous-phase LPS and their methanolysis products, and CE-ES-MS...
... presence of various metal concentrations and metal combinations was determined Figure shows the inactivation courses of apo-TNXI andof TNXI in the presence of mm concentrations of each ofthe three ... II XIs from the mesophiles E coli (ECXI) and Bacillus licheniformis (BLXI), for the moderate thermophile Thermoanaerobacterium thermosulfurigenes (TTXI), and for the hyperthermophile Thermotoga ... stabilization of BLXI and TTXI relative to their apo forms, the effect was smaller for ECXI and almost negligible for TNXI (Fig 2) The melting temperatures (Tm, the temperature at the maximum ofthe heat...
... mixing the human CPR FMN domain with its FAD/NADPH domain (% 16-fold) (29) However, the domain mixture still reconstituted only % 2% ofthe activity ofthe full length CPR In the case of NR1, the ... spectroelectrochemical titrations ofthe isolated FAD/NADPH and FMN domains of NR1 enabled the determination ofthe midpoint reduction potentials for the oxidized/semiquinone (E1) and semiquinone/hydroquinone ... kinetic properties of NR1, and as we have shown for CPR and P450 BM3 (23,24,28) the properties ofthe flavin binding domains of NR1 are likely to mimic the redox properties ofthe domains in full-length...
... risks The results of this study provide the first formal estimates ofthe joint effect of derivative exposures on the systematic interest rate and exchange rate risks of U S banks The rest ofthe ... investigate the effect of traditional off-balance sheet activities on bank risk and profits in general, and not focus on the effect of derivatives on systematic exchange rate and interest rate risks of ... to examine the nature of these covariances in more detail To this end, suppose beginning ofthe period The bank’s net asset at the end ofthe period in dollar terms is (6) where q and q* are...
... notions of it.5 His central hypothesis is that painted landscape constitutes 'not the nature ofthe physical world but the nature of our reactions to it.'6 In other words, the visualisation of a landscape ... Enquiry into the Origins of Our Ideas ofthe Sublime andthe Beautiful, described as 'perhaps the most influential discussion of sublimity produced in the eighteenth century.'11 The legacy ofthe eighteenth-century ... abnegation ofthe 'otherness' of this foreign landscape—it is neutralised by the European envisioning and representation of it in terms of its sentimental effect on the viewer This strategy of visualisation...
... Effects of deletion ofthe GTPase domain on the 16S rRNA-binding activity of Era Results Effects ofthe deletion ofthe RNA- and membranebinding domains of S pneumoniae Era on the GTPase activity of ... the membrane- and RNAbinding sites of Era overlap To further understand the inhibition of liposome on the binding of Era to poly(U), we analyzed the effects of different component lipids ofthe ... previously, the KH domain of Era is required for the binding ofthe protein to 16S rRNA, and part ofthe domain is also required for the binding ofthe protein to membrane Thus, the regions critical...
... scores for the DQOL andthe D-39S and higher scores for the RAND-12 # PHC: physical health composite; MHC: mental health composite the RAND-12 the discriminative ability ofthe DQOL andthe D-39S ... estimated a standard error of measurement (SEM) which accounts for reliability ofthe DQOL and standard deviation of patients under the investigation SEM was estimated by a standard deviation ofthe DQOL ... ofthe DQOL against the D-39S andthe RAND-12 In general, domain scores ofthe DQOL were moderately correlated with the D-39S (except sexual functioning) andthe RAND-12 PHC and MHC, with Pearson's...
... participated in the study designand led the writing ofthe manuscript, EB carried out the data analysis and participated in writing the manuscript, KOB participated in the study designand critically ... Child-OIDP and some ofthe associations between the Child-OIDP and proxy measures were not significant While the low value of alpha is affected by the nature ofthe Child-OIDP index andthe fact that ... Brent Medical Ethics Committee, the Research and Development Panel ofthe Bedfordshire Heartlands Primary Care Trust andthe Research and Development Directorate ofthe University College London...
... DNA) The LAMP reaction was performed at 65°C for 30 and 60 min, and compared with the results ofthe standard PCR assay There was no difference between the detection limit ofthe LAMP reaction and ... Africa, and Thailand (unpublished data) Clinical signs of KHV are often non-specific and mortality may occur rapidly Discoloration and severe necrosis ofthe gills is the most consistent sign of infection, ... Nucleotide sequence ofthe KHV construction ofthe inner Nucleotide sequence ofthe KHV amplicon (GenBank accession number AF411803) used for construction ofthe inner and outer primers The primer sequences...
... DNA) The LAMP reaction was performed at 65°C for 30 and 60 min, and compared with the results ofthe standard PCR assay There was no difference between the detection limit ofthe LAMP reaction and ... Africa, and Thailand (unpublished data) Clinical signs of KHV are often non-specific and mortality may occur rapidly Discoloration and severe necrosis ofthe gills is the most consistent sign of infection, ... Nucleotide sequence ofthe KHV construction ofthe inner Nucleotide sequence ofthe KHV amplicon (GenBank accession number AF411803) used for construction ofthe inner and outer primers The primer sequences...