structure of chromatin in human sperm bound to hyaluronic acid the benefits of picsi dish mediated sperm selection
the speed of visual processing of complex objects in the human brain. sensitivity to image properties, the influence of aging, optical factors and individual differences.
... THE SPEED OF VISUAL PROCESSING OF COMPLEX OBJECTS IN THE HUMAN BRAIN Sensitivity to image properties, the influence of aging, optical factors and individual differences ... problematic mainly because there is no agreement within the EEG research field regarding the exact nature of the information carried within the EEG waveform, including the exact meaning of ERP peak latencies ... through the ventral stream, there is a gradual decrease in the retinotopy of cortical areas (responses of single neurons in the IT cortex become independent on the object‘s position in the visual...
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peer-to-peer harnessing the benefits of a disruptive technology
... 1.2 The network model of the Internet explosion (1995-1999) The explosion of the Internet in 1994 radically changed the shape of the Internet, turning it from a quiet geek utopia into a bustling ... services come into being by leveraging the untapped power of the millions of PCs that have been connected to the Internet in the last five years 2.3.1 PCs are the dark matter of the Internet Napster's ... limited Ruin is the destination toward which all men rush, each pursuing his own best interest in a society that believes in the freedom of the commons Freedom in a commons brings ruin to all In the...
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Advanced PIC Microcontroller Projects in C from USB to RTOS with the PIC 18F Series _ www.bit.ly/taiho123
... 1.22 Converting a Floating Point Number into Decimal To convert a given floating point number into decimal, we have to find the mantissa and the exponent of the number and then convert into decimal ... Remainder (LSD) Remainder Remainder Remainder Remainder Remainder Remainder (MSD) The binary number is 11110102 1.8 Converting Binary Numbers into Hexadecimal To convert a binary number into hexadecimal, ... Converting Binary Numbers into Decimal To convert a binary number into decimal, write the number as the sum of the powers of Example 1.1 Convert binary number 10112 into decimal Solution 1.1 Write the...
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Tài liệu Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131 pptx
... Hz) of the backbone couplings for Tyr4 and His6 are possibly the result of twisting or bending in the middle of the amino -acid sequence of the hormone [49] Structure calculations and analysis The ... investigated, on the grounds that this parameter is involved in their binding to the receptor As a corollary of this argument, it has often been assumed that the conformation of the hormone in ... amino acid) This specific conformational feature may be of importance for the conformation of the AII complexed to the AT1 G-protein-coupled receptor and the activation of the receptor Interestingly,...
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Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt
... correspond to the flexible importin-b binding domain The importin-b binding domain is known to have an autoinhibitory function, whereby an internal NLS-like sequence competes for the importin-a binding ... reducing binding affinity for cargo proteins and helping to facilitate the release of the cargo within the nucleus [10,11] The removal of the autoinhibitory domain to create a truncated importin-a ... cargo binding sites, referred to as the major and minor binding sites [1] These sites are located in the concave face of the protein near regions of invariant Trp and Asn arrays The major binding...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... upregulation in the liver of streptozotocin-induced diabetic rats and the suppression of such elevation following insulin injection [21,22], we decided to investigate the effect of FEBS Journal ... [21], the hACMSD:DHAP complex represents the first structure of an ACMSD in a ligand -bound form and can be used to provide insights into catalysis In particular, the residues involved in inhibitor ... located in the proximity of the zinc ion and with the hydroxymethylene group pointing toward Pro295 DHAP interacts with the catalytically essential Zn2+ through mediation of the metal-coordinating...
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Báo cáo khoa học: Identification of carbonic anhydrase 9 as a contributor to pingyangmycin-induced drug resistance in human tongue cancer cells ppt
... domain containing 10 Mediator complex subunit 11 Transmembrane protein 85 Ubiquitously expressed transcript isoform Nardilysin (N-arginine dibasic convertase) l-Protocadherin isoform Protein kinase ... factor target (fibroblast growth factor receptor substrate 2) Small GTP-binding protein rab22b Minichromosome maintenance protein homolog Ribosomal L1 domain containing Hepatocellular carcinoma-associated ... protein S4, X-linked Desmuslin isoform B; desmuslin isoform A Histone cluster MYST histone acetyltransferase (monocytic leukemia) Guanine nucleotide-binding protein (G protein), c11 Polyglutamine-binding...
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Báo cáo khoa học: Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopy ppt
... containing an extracellular ANPbinding domain (ECD), a transmembrane domain, and an intracellular domain consisting of an ATP-binding regulatory domain and a GCase catalytic domain [8] ANP binding ... change in its environment On the other hand, if the ECD assumes the tt dimer structures, no change is expected in the Trp environment in response to ANP binding On the basis of the above structure ... domains in the opposite direction without an appreciable change in the interdomain distance (B) Schematic presentation of the movement of the juxtamembrane domains in response to ANP binding...
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Báo cáo khoa học: Secondary structure of lipidated Ras bound to a lipid bilayer pptx
... spectroscopy of membrane -bound Ras protein as a new tool, paving the way to revealing the dynamic interactions of membrane -bound N-Ras protein with its effectors and regulators (i.e Ras binding domain of ... After the formation of the model membrane, protein incorporation was initiated by mixing the protein into the sample solution on the surface The starting bulk concentration of the protein was ... solution Furthermore, it resembles the mean of an ensemble of 20 structures and thus indicates the dynamics of the protein, leading to changes in secondary structure according to the stride algorithm...
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Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
... Activation of RAS was evaluated in platelets through the ability of the activated RAS–GTP to bind a GST fusion protein containing the RAS-binding domain of RAF Different platelet agonists including ... contributes to activation of the RAS–ERK signalling pathway [16] The SRC kinase family inhibitor PP1 inhibited activation of RAS in response to thrombin Activation of RAS by G coupled-receptors in other ... able to bind to its components For example, the RAF kinase inhibitor protein can bind RAF and MEK and thereby prevent their interaction [28,29] A reduction of the expression of the scaffolding...
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HYGIENIC PHYSIOLOGY WITH SPECIAL REFERENCE TO THE USE OF ALCOHOLIC DRINKS AND NARCOTICS BEING A REVISED EDITION OF THE FOURTEEN WEEKS IN HUMAN PHYSIOLOGY ppt
... upper, and the lower They closely resemble each other The arm corresponds to the thigh; the forearm, to the leg; the wrist, to the ankle; the fingers, to the toes The fingers and the toes are so ... caresses lovingly the downy cheek of the infant, and rests on its head invoking the blessing of Heaven, _Wonders of the Human Body_.] FIG 13 [Illustration: _The Mechanism of the Hip Joint._] THE LOWER ... variety of joints These joints further enable the foot to be applied, without inconvenience, to rough and uneven surfaces. HINTON.] The toes naturally lie straight forward in the line of the foot...
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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... present in duplicate copies within the C1 complex, forming a tetramer Both the autoactivation of C1r and the activation of C1s require large-scale movements of the different domains of the proteases ... observed in the intermodular linker and at the F–G turn in CCP2 This suggests that both modules maintain their modular integrity; nevertheless, there is a well-defined interface region between the ... contrast, the large flexibility of the E–F loop in CCP2 seems to be retained in the tandem construct R2 values, bearing information on ls to ms motions, are higher in both modules of the tandem...
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INTERACTIONS OF POLYMERS WITH FIBRILLAR STRUCTURE OF CELLULOSE FIBRES: A NEW APPROACH TO BONDING AND STRENGTH IN PAPER docx
... performed to evaluate the influence of different polymers at macroscopic level on the development of bonding and strength in paper The main objectives of the work were: 1) to further the understanding ... other in the orientation of the microfibrils along the fibre axis S2 layer is considered as the main load bearing element in wood fibres and both the thickness and the microfibril angle of the ... to study the fibre bonding and paper strength, and the mechanisms of action of different paper strength additives The main objectives were the following: first, to further the understanding of...
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Báo cáo khoa học: The intrinsic structure of glucose transporter isoforms Glut1 and Glut3 regulates their differential distribution to detergent-resistant membrane domains in nonpolarized mammalian cells potx
... unique sorting machinery to A B Fig The topology of Glut1 and alignment of the deduced amino acid sequences of Glut1 and Glut3 (A) The predicted structure of Glut1 [1] The position of the single endogenous ... amino acids of Glut3 By contrast, chimera N31 contains the first 12 amino acids of the N-terminal tail of Glut1 and, subsequently, amino acids 11–496 of Glut3 The location of the FLAG-tag is indicated ... of Glut1A Chimera A contains amino acids 1–10 of Glut3, amino acids 13–271 of Glut1, and amino acids 291–496 of Glut3 Chimera B also contains amino acids 1–290 of Glut3, amino acids 272–450 of...
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Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot
... with the nucleobases pointing towards the protein surface The 5¢ -to- 3¢ polarity of the ligand follows that of most other nucleic acid complexes of OB-fold proteins, starting in the vicinity of ... sheet of The Bc-Csp domain swap provides insight into the folding and misfolding of the CSP The Bc-Csp domain swap occurs in the middle of loop L34 and is promoted by a unique combination of torsion ... conformation of dT6 oligonucleotides in the binding site, the unstacking of bases with respect to each other upon binding, and the shielding of the nucleobase head groups by the protein suggest that the...
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Báo cáo khoa học: Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3 pdf
... Results Synthesis of recombinant human TTR In the crocodile, TTR is only synthesized in the liver during development in the egg and in hatchlings and only in the choroid plexus of the adult Thus, ... recombinant TTRs as tetramers Analysis of binding to retinol-binding protein and thyroid hormones showed that the recombinant TTRs retained its function as binding protein for retinol-binding protein ... recombinant proteins To ascertain whether unwanted post-translational modifications occurred to the recombinant TTRs in P pastoris, properties of the proteins were analyzed Binding to RBP Recombinant...
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Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx
... potential during all but the last 200 cooling steps Of the 60–97 structures resulting from the final round of structure calculation, for each of the three solvents those 20 structures showing the lowest ... were able to neutralize the high intrinsic oligomerization propensity of the peptide Thus, the following discussion is based on the structure found for the micelle-containing solution The a helix ... that the helical region studied in the present work contains essential elements for HHR23A interaction of Vpr The structure of the ubiquitin associated (UBA) domain of HHR23A, reported to be...
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Báo cáo khoa học: "A CONSIDERATION ON THE CONCEPTS STRUCTURE AND LANGUAGE IN RELATION TO SELECTIONS OF TRANSLATION EQUIVALENTS OF VERBS IN MACHINE TRANSLATION SYSTEMS" doc
... relation to human becomes closer and the more the level of abstract of the noun becomes lower the numbers of verbs that are closely related to them ~id therefore have to associate to them (nouns) ... (1) Find a pair of verb and associated translation equivalent ( D o , Play : ~ - & ) that can be associated in common to a part of the structure of the categories as in Fig.l, and then find appropriate ... equivalents in detail at the lower level categories (2) To each verb found in the process of the association, consults ordinary dictionary of translation equivalents and word usage of verbs and obtain the...
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc
... efficient in the NOD mouse model, as well as in other murine models of T1D [95-100] The feasibility of translating these therapies to humans remains to be assessed One potential limitation of the process ... protection have yet to be examined Page of 12 In humans, exposing CD4+ T cells to both IL-2 and rapamycin in vitro leads to an increase in the cellular frequency of FOXP3+ T cells, originating from nTreg ... been examined The major challenge in this case is the very low abundance of Treg cells The possibility of expanding and/or differentiating Treg cells in vitro prior to re-infusing them into patients...
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báo cáo sinh học:" The precarious supply of physical therapists across Canada: exploring national trends in health human resources (1991 to 2005)" pptx
... Province Figure the ratio of PTs the change in population vs the change in A comparison ofto 10,000 population: 1991 to 2005 A comparison of the change in population vs the change in the ratio of ... growth will include a significant increase in the proportion of the population over the age of 65 years [24] Though the population of the nation continues to increase, positive growth is not necessarily ... growth in of 10 provinces Growth in the absolute number of physical therapists Similar to the overall Canadian population, the absolute number of PTs also grew between 1991 and 2005 According to...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25