structure function and numbers
Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below) Prior to the resolution, CcStP and ... R226A and R242A mutants (Table 1), all enzymes were stable for h in the presence of mM potassium phosphate and potassium sulphate Reconstitutions with PLP of apo-Cc StP and mutants thereof, and...
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Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc
... the mouse, fly and worm, and more exciting discoveries are no doubt on the way On the other hand, the function of plant serpins represents an obvious deficiency in our global understanding of the ... crystallography and this meeting proved no exception; in addition to published work, 10 unpublished serpin structures were presented affording major new insights into serpin function and providing ... serpin function and dysfunction in the coagulation cascade In a related talk, Daniel Johnson (Cambridge Institute for Medical Research, UK) provided an elegant structural explanation for dysfunction...
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A study on structure, function and diachronic evolution of chinese extended middle construction
... Yang Lili and Wu Yayun, for their friendship and the happy days we have been together Finally, I would like to thank my parents, my sister and brother for their love, understanding, and patience ... intriguing semantic relations and syntactic features have prompted many scholars debating its particularity and intrinsic properties This study explores the structure, function, and historical developments ... descriptive and illustrative context where Chinese extended middle construction emerges and put forwards that this construction is a double-topic nested structure The issue of how its form and meaning/function...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc
... regions based on prior structural and functional imaging data that related structure to cognitive functions of interest (see Greenwood, 2007; Raz, 2005; Reuter-Lorenz and Lustig, 2005 for recent reviews) ... were standardized (z-transformed) and combined into six theoretically motivated composite scores (attention, verbal memory, visuospatial memory, speed of processing, executive functions and language) ... test (Delis et al., 2001), and the Trail Making Test B (Reitan and Wolfson, 1985) Speed of processing was assessed with the TrailMaking Test A (Reitan and Wolfson, 1985) and the Symbol-Digit Modalities...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
... al [15] determined the structures of E75Q and E75L mutants of rcSHMT and studied their properties However, the structures determined by them were not at high resolution and suffered from a lack ... we determined the structure of E53QbsSHMT and its binary complexes with Gly, l-Ser, l-allo-Thr and ternary complex with Gly and 5-formyl-THF (FTHF) In addition, the biochemical and spectral properties ... bsSHMT (Blue) Y51 and the Schiff base are in the same orientation in E53QbsSHMT and bsSHMT, whereas the orientations of E53, Y60 and Y61 have changed ˚ wild-type and mutant structures is 0.10...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
... hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, but on the other hand ... permeabilized T-cells and induced both local and global Ca2+ signalling in intact T-cells [46] 8-Azido- and 8-NH2-cIDPRE performed similarly (Fig 4) whereas the halogenated compounds 8-Br- and 8-Cl-cIDPRE ... (2005) 4590–4597 ª 2005 FEBS 4591 Second messenger function of cADPR (ADPRC) and thereby induce the formation of cADPR (Fig 2) G-protein coupling and Tyr phosphorylation have been implicated in...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx
... three distinct forms, and the structure of form A solved The enzyme is a homodimer, and the structure shows two domains in the a subunit Ó FEBS 2002 Structure, mechanism and function of prenyltransferases ... molecular dyad axis The seven a helices and six b strands are shown in red and green, respectively, for subunit A, and in magenta and cyan for subunit B, and they are labelled separately The blue ... two a helices (a2 and a3) and four b strands (bB, bA, bD, and bC) as shown in Fig 5A In contrast with the symmetric structure of M luteus UPPS, two protein conformations (open and closed forms)...
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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot
... pedal and hypobranchial glands in different species of this class In mollusks which lay their eggs in rigid capsules, capsule glands and albumin glands are present in a complex of pallial glands ... development and functioning of the reproductive systems Octopus and cuttlefish females are functionally mature at the end of stage IV (stages V and VI occur at spawning) Female squid are usually functionally ... that during the juvenile phase and through physiological maturation, the gonad and accessory glands function asynchronously At physiological maturity these two organs function synchronously Preliminary...
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Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx
... aminoglycosides Thus, a new set of poly arginine 6-mer and 9-mer d- and l-aminoglycoside conjugates (APACs) was designed and synthesized, and their cell uptake and antiviral activities were determined We ... HIV-1 Tat responsive element (TAR) RNA binding, NMR structures of TAR–ligand complexes and aminoglycoside–RNA interactions, we have designed and synthesized a set of conjugates of aminoglycoside ... interaction with CXCR4 and compete with its natural ligand SDF-1a to CXCR4 Results Synthesis and chemical characterization of APACs The synthesis of the regioselectively functionalized aminoglycosides...
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Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt
... the structure and function of the enzyme by mutating Val106 to amino acids differing in polarity, size and conformation, and subsequently investigating their effect on the quaternary structure and ... [28] The amino acid sequence identity is 34% between dNK and dGK [29], and 47% between dGK and dCK [28], and the structures of dNK, dGK and dCK appeared to be very similar [27,28] Despite the ... glycerol and mM dithiothreitol) with and without 2.5 mM ATP, and incubated on ice for h before storage at )80 °C The enzymes incubated and stored with and without ATP are referred to as the +ATP and...
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Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc
... demands are imposed on the sensitivity and selectivity of the methodology, which should provide molecular structure and dynamics information In this article, we present the potential of Raman and ... physiological processes of cytochrome c Methodology Raman and IR spectroscopy are molecular structuresensitive techniques, as the frequencies and band intensities of vibrational transitions represent ... field effects on protein structure, dynamics, and function Information provided by surfaceenhanced vibrational spectroscopy Redox proteins immobilized on SAM-coated Ag and Au electrodes are usually...
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Báo cáo khoa học: An asymmetric ion channel derived from gramicidin A Synthesis, function and NMR structure ppt
... types: those between aHi and NHi+6 (i ¼ 1, 3, and for chain A, and 1, 3, 5, 7, and for chain B); and those between aHi and NHi-6 (i ¼ 10 and for chain A, and 14, 12, 10, and for chain B) These ... The left-handed doublehelix structure transformed into two single-stranded right-handed b-helices with 6.3 residues per turn Whereas the left-handed double b-helix is consistent with the structure ... A and Trp15 of chain B are highly uncertain (with three and four unambiguous data points and R of 0.98 and 0.98, respectively) Fig NOESY spectrum (150 ms) in the region of (F2) 9.7–8.0 p.p.m and...
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Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx
... performed to understand the physiological function of the 4-kDa peptide, and suggests that this peptide is involved in the regulation of callus growth and cell proliferation Tertiary structure of the ... °C, and washed twice with Tris/NaCl/Pi for Finally, the cross-reacted bands were detected with alkaline phosphatase substrate (Moss, Maryland) Results and discussion Possible physiological function ... octadecanoid Ó FEBS 2003 Possible function and structure of a 4-kDa legume peptide (Eur J Biochem 270) 1275 Fig Ribbon representation of insulin and the 4-kDa peptide (A) Solution structure of human insulin...
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Báo cáo toán học: "Short term interactions between tree foliage and the aerial environment: An overview of modelling approaches available for tree structure-function model" potx
... fuel economy and pollutant capture in urban environment [50, 85] The framework of tree structure function models is primarily aimed at understanding tree growth and development Functional-structural ... interactions between tree structure, function and the environment Such models are structural-functional tree models sensu stricto and should include both instantaneous and delayed tree responses ... = H + E (5) where Rn and M are the net gains of energy from radiation and metabolism, respectively, and H and E are losses of sensible and latent heat, i.e by convection and evaporation, respectively...
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Báo cáo khoa học: " Avian reovirus L2 genome segment sequences and predicted structure/function of the encoded RNA-dependent RNA polymerase protein" docx
... strains of ARV (ARV138 and ARV176) in order to expand the available ARV sequence database, determine sequences of the ARV RdRp protein, and to delineate conserved structure/ function features of ... CSRV, and AqRV GCRV are aligned (Fig 1) Thus, to gain structure/ function information about this key viral-encoded enzyme, ARV, MRV, and AqRV identical amino acids, conservative substitutions, and ... MRV, and AqRV RdRp protein sequences (Fig 1, closed circles) Amino acid identities between ARV λB and homologous MRV λ3 or AqRV VP2 are ~55% and ~42%, respectively (Table 3), suggesting the ARV and...
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Báo cáo y học: " Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease" potx
... fluticasone and salmeterol, both separately and in combination, on lung structure and function in allergically inflamed mice Salmeterol alone worsened airways hyperresponsiveness and increased ... epithelial cells containing airway mucin was greatest in the V and S groups and was significantly less in the F and FS groups (Figures and 7) There was a trend for increased PAFS positive cells in ... Groups include naïve mice (N) and OVA sensitized and challenged mice treated with vehicle control (V), salmeterol (S), fluticasone (F), and a combination of fluticasone and salmeterol (FS) Results...
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HUMAN MILK OLIGOSACCHARIDES: CHEMICAL STRUCTURE, FUNCTIONS AND ENZYMATIC SYNTHESIS
... The motif with terminal structure Fucα1-2Gal is H antigen, and H antigen is attached to GlcNAc with β1,3 and β-1,4-linkages to create H1 and H2 antigens, respectively A and B antigens are formed ... oligosaccharides: chemical structure, functions and enzymatic synthesis Figure Anti-adhesive and glycome-modifying effects of HMOs (adapted from Bode L, 2009) “Most bacteria (commensals and pathogens) express ... Fierfort and coworkers (2008) and Drounilard and coworkers (2010) have successfully developed a microbiological process to economically produce 3′sialyllactose (Fierfort and Samain, 2008) and 6′sialyllactose...
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Structure - Grammar and Style
... between clear, smooth sentences and sentences that are clunky and confusing: misplaced or dangling modifiers, parallel structure, and wordiness and redundancy M ISPLACED AND D ANGLING M ODIFIERS Be ... Incomplete sentence and consists of 15 incomplete sentences ( structure sentences with underlined words and phrases will be questions) and Part B consists of 25 sentences with presented at random underlined ... water level in the reservoir and tested it for contaminants Horace and Renee both told the detective a different story 55 – STRUCTURE: GRAMMAR AND STYLE – I NDEPENDENT AND D EPENDENT C LAUSES A...
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Tài liệu Chapter 2: Indicators of Financial Structure, Development, and Soundness ppt
... institutions and their asset positions, and (b) the number of and growth rates of 10 11 12 A B C D E F G H I 16 Chapter 2: Indicators of Financial Structure, Development, and Soundness available money and ... A Handbook bonds, equities, and derivative and structured finance products) should also be covered For financial institutions, the structural overview should focus on identifying the number and ... regulation and accounting standards often have provided incentives for developing new ways to manage risks (e.g., asset and liability management for insurance company and pension funds) and have...
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