... Thi Tam 24 b) The compressibility of material has an influence on thestabilityof structure ∗ The more the Poisson coefficient ν decreases, the more the value of σu diminishes when a the ratio is ... On thestabilityof elastoplastic thin triangular plates made in 15 ofthe strain velocity tensor detemined by the stress-strain relationship of elastoplastic process theory [1, 7] are ofthe ... (s) = φ (s) - the tangential modulus, Ec (s) - the secant modulus ofthe material The problem determining critical loads of a plate reduces to seek the critical value s∗ Finally the critical...
... stratum was calculated as: (the sum ofthe MOS of all PSUs within the stratum) (the number of PSUs drawn within the stratum) x (the MOS ofthe drawn PSU) The sampling weight of a drawn clinic within ... at the day ofthe field work The final sampling weight of any person drawn in the clinic sample is then equal to the sampling weight ofthe relevant clinic multiplied by the total number of persons ... number of beds is between 31 and 80, then the hosp_MOS = 2; • If the number of beds is between 81 and 150, then the hosp_MOS = 3; • If the number of beds is between 151 and 300, then the hosp_MOS...
... for halting further negative impact ofthe epidemic Objectives There were four specific objectives ofthe satellite meetings: • To communicate the progress ofthe multi-country HIV prevention ... Researcher in the office ofthe CEO at the Human Sciences Research Council in Cape Town At the time of writing, Kristin Roe was a CIDA-funded intern with the Social Aspects of HIV/ AIDS Research ... during the implementation phase ofthe project 11 EXPLORING THE CHALLENGES OF HIV/ AIDS Progress in SADC countries The Healthy Relationships intervention component Over the past two years each of the...
... highlights the interaction of four of these factors: • The nature ofthe HIV/ AIDS pandemic at the local level, including its prevalence and, importantly, duration, as well as the levels of stigma ... way of introduction we draw attention here to two of these The first is the challenge of distinguishing the impact of HIV/ AIDS from other influences on tenure, not least population pressure, the ... recommendations ofthe FAN study are that: the review of land-related policies take the impact of HIV/ AIDS into account; initiatives related to HIV/ AIDS should address themselves to the land problems of vulnerable...
... cutoff distance (rc ẳ 6.0 A) The dynamics ofthe resulting network are then dened by the Ni ã Nj Kirchhoff connectivity matrix of interresidue contacts (G) where the off diagonal elements of ... some of these phenomena may be interconnected within the catalytic mechanism ofthe enzyme Structural insights into the mechanochemical nature of a-CT catalysis A more detailed analysis ofthe ... electrostatic potentials (EP) for the Ne ofthe lysine residues of a-CT at pH EP, EwaldEi EP is the Ewald energy of placing a charge of +1 at the location ofthe ith ionizable atom [89] Reactivity...
... binding ofthe polyadenylated rpsO RNA We have shown that the presence ofthe remainder ofthe acidic tail results in the thermodynamic stabilization of Hfq by 1.8 kcalÆmol)1 A comparison ofthe ... full-length protein Based on the analysis ofthe transition region, the conformational stabilityofthe proteins can be calculated [29]: the free energy when Ó FEBS 2004 The role ofthe C-terminal domain ... noted that the C-terminal domain of Hfq seems to be located at the same position as that ofthe Sm-like SmAP3 ofthe archaea P aerophilum [31] and, as in the case of SmAP3, the possibility of two...
... cause the fund to break the buck, only to later provide support Accordingly, many ofthe instances of support towards the end ofthe five year period reviewed were a small percentage ofthe funds’ ... Jones for their contribution to the data gathering effort The views expressed in this paper are those ofthe authors and are not necessarily reflective of views at the Federal Reserve Bank of Boston ... realized by the fund sponsor Instead, in the case of a security purchase, it is indicative ofthe loss that would have been realized by the fund sponsor if it had disposed ofthe security on the same...
... least the first months of treatment among patients with advanced HIV disease 8, Predicting Drug Interactions Involving Rifamycins Knowledge ofthe mechanisms of drug interactions can help predictthe ... availability ofthe drug, limit the use of rifabutin in the treatment of HIV- related tuberculosis Rifabutin and Protease Inhibitors Rifabutin has little, if any effect on the serum concentrations of protease-inhibitors ... dose of protease-inhibitor at the same time as the directly observed dose of tuberculosis treatment Special Populations Pregnant women A number of issues complicate the treatment ofthe HIV- infected...
... stabilityof CPU’s activity, especially the YQ mutant Following the first round of FINDTM treatment, 50% ofthe mutants with improved thermal stabilityof their activity appeared to bear mutations in the ... connected to an increased thermostability ofthe protein itself, we monitored the thermal unfolding of WT and YQ proCPU-CHis Compared with the WT, the midpoint temperature (Tm) ofthe protein-unfolding ... fibrinolysis, the development of CPU inhibitors as pro-fibrinolytic agents is an attractive concept [15,16] But the instability ofthe enzyme has prevented crystallization of CPU and the use of structurally...
... This paper is based on the talk given at the Conference on Mathematics, Mechanics, and Informatics, Hanoi, 7/10/2006, on the occasion of 50th Anniversary of Department of Mathematics, Mechanics ... Tran Kim Thanh, On the characterization ofthe distribution ofthe composed random variables and their stabilities Dotor thesis, Hanoi 2000 [2] Tran Kim Thanh, Nguyen Huu Bao, On the geometric composed ... composed variables and the estimate ofthe stable degree ofthe Renyi’s characteristic theorem, Acta Mathemaica Vietnamica 21 (1996) 269 [3] C G Essen, Fourier analysis of distribution functions,...
... introduced alanine at these two positions, with the aim of determining whether any ofthe observed effects were a result of changes in the size and charge ofthe amino acid at these positions Results ... at 37 °C, the significantly lower yield ofthe variants may also be the result of dissociation followed by proteolysis ofthe monomers The effects of these mutations on temperature stability is ... the conformation of this loop Changes in the conformation ofthe backbone at this point and changes in the orientation of other side chains, as a result ofthe introduction ofthe large charged...
... between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface ofthe protein because ofthe interactions ofthe cofactor with the protein ... are comparable, the Tg values ofthe proteins vary slightly; there is a difference of almost C between the Tg values ofthe proteins, the value being higher for the holo form There have been ... bonds The 4Â-PP group is linked to the protein by the Ser37 O-c atom Only residues 3138 ofthe protein make extensive contacts with the cofactor For the sake of better understanding ofthe interactions,...
... cmÀ2) Decay of PL intensity is a good indication ofthestabilityof porous silicon particularly ofthe surface bond configurations [3,16] In Fig 4(A), decay ofthe PL intensity at the peak wavelength ... artifact ofthe substrate (textured one) rather than that ofthe electrolyte alone On the textured surface, the nucleation of nanopores is preferentially initiated at the boundaries between the pyramids ... The photochemical etching method with H2O2 solution does not generate a toxic material unlike in the case of HNO3 [11] Moreover, the addition of H2O2 to the etching mixture raises the pH of the...
... responsible for most ofthe steps in the biosynthesis ofthe oligosaccharide portions ofthe LPS molecules The inner core of H influenzae LPS has been found to consist ofthe triheptosyl oligosaccharide ... H-2 H-3, H-5 H-2 H-3, H-5 H-5 of Kdo H-3 of HepI; H-1 of HepIII H-1, H-2 of HepII H-4, H-6 of HepI H-2, H-3 of HepII H-1, H-2 of HepIII substituents The structure ofthe OS backbone in 11-OS-1 and ... from the area ofthe ions relative to the total area (expressed as percentage) Signals representing less than 5% ofthe base peak are not included in the table Ó FEBS 2004 LPS glycoforms of nondisease...
... that, unlike the wild-type, the C-terminal domain deleted KcsA cannot form tetramers in vivo Nevertheless, whether the lack of expression ofthe tetramer is caused by the absence ofthe tetramerization ... thermostabilities ofthe wild-type and mutant KcsA constructs were compared at basic and acidic pHs because thestabilityof KcsA depends on the pH ofthe solution: the tetrameric form ofthe wild-type ... control ofthe excitability of membrane, release of neurotransmitter, regulation of osmotic pressure and regulation ofthe size of cell) A structural and functional understanding of these channels...
... all the peptide is in the water or lipidic phase, respectively; cL is the lipidic molar volume [26] and [L] is the concentration ofthe lipid accessible to the peptide (the outer leaflet ofthe ... reach the point where all ofthe membrane is homogeneous The MPRP-C is insensitive to the cholesterol content in the membrane, which is in agreement with the insensitivity ofthe peptide to the ... destabilizing them [15,16] and the presence of cholesterol and sphingomyelin (major components ofthe viral membrane) have an important role for the membrane perturbing actions ofthe peptide [17,18] There...
... the equivalent residues ofthe mannose complex (subunit B in the asymmetric unit) The water molecules clearly mimic the oxygen atoms of bound mannose (black, thick lines) (B) Stereo view ofthe ... interactions of mannose in the monosaccharide binding site The beta-anomeric oxygen position of mannose is drawn in light green, as is the corresponding orientation ofthe side chain of Glu221 The second ... out of 10 sugar residues The final model ofthe carbohydrate is superimposed (B) Stereo view ofthe interactions between NA2F and PAL The heptasaccharide moiety of NA2F that is visible in the...