stimulus reinforcer association learning and reversal in the orbitofrontal cortex involving conditional reward neurons and negative reward prediction error neurons
... fasting insulin concentrations and Homeostasis Model Assessment of Insulin Sensitivity (HOMA %S) Results CSH1.01 genotype and fathers' fasting insulin There was no association between father's ... to low insulin-mediated growth in utero and insulin resistance in adulthood [6] It has been proposed that infant length or weight measured up to the age of two increasingly reflects the influence ... D1/T or D2/T genotype and fasting insulin (Table 1) The P values for fathers' fasting insulin were little changed by adjustment for age and BMI (P = 0.53 and 0.29 for the D1/T and D2/ T genotypes,...
... information Inthe late 1990s, the USA had taken the lead in transforming the international accounting standards (IAS) into the international financial reporting standards (IFRS), thus from accounting into ... lodging control inthe hands of key stakeholders, normally the consuming or producing members Maintaining and refining that control, however, will always be a challenge, even in an age of expanding ... cooperative rationality The international cooperative standards The first layer in understanding the cooperative rationality: the international definition The second layer in understanding the cooperative...
... Medicine (PCM, NUS), the lecturers inthe Graduate Programme of Yoog Loo Lin School of Medicine (SOM, NUS), andthe staffs inthe NUS libraries for all their help, support, and instruction inthe ... such as karaoke and line dancing Productive activities included gardening, painting, and other hobbies, preparing meals, shopping, community work and other employment or business Continuous (summed ... metabolites together andthe inconsistent findings, the independent effects of homocysteine, folate and B12 on physical performance and functional disability therefore require further investigation...
... more, there are two possibilities: either providing more training data, or considering more features To investigate the effect of the size of the training data we have computed thelearning curves ... the three classifiers Figure shows the C4.5 learning curve for the overall experiment on nouns and pronouns; thelearning curves for the other two classifiers are similar, and not included inthe ... 1: Learning curve for the C4.5 classifier The curve is interesting, showing that after only 1% of the training set (1961 instances) C4.5 can already 119 The results show that the model trained...
... hrs after the administration of morning dose of insulin and curcumin The results were expressed in terms of milligram per decilitre of blood Total Dopamine receptor binding studies inthe cerebellum ... receptor binding parameters were determined using Scatchard analysis [32] The specific binding was deter- Page of 11 mined by subtracting non-specific binding from the total The binding parameters, ... activity in diabetic mice, but not in non diabetic mice [46] In our study, curcumin and insulin increased the dopamine D1 receptor expression levels inthe cerebellum, which suggests that the curcumin...
... proliferation and differentiation is a novel approach In rats, 5-HT neuronsinthe brainstem raphe are among the first neurons to differentiate inthe brain and play a key role in regulating neurogenesis ... was obtained by subtracting nonspecific binding inthe presence of 100 μM unlabeled MK-801 from the total binding Protein Determination Figure Apomorphine induced rotational behaviour in experimental ... of the Receptor-Binding Data Linear Regression Analysis for Scatchard Plots The data were analysed [25] The specific binding was determined by subtracting non-specific binding from the total The...
... their work and appreciating their colleagues' assumptions Team learningand open systems thinking depend upon each person understanding the mental models they hold themselves, and understanding ... teaching the crafts of reading, writing and mathematics' In Knowing, Learningand Induction Edited by: Resnick LB New Jersey: Earlbaum; 1989 Snell R, Chak AM-K: Thelearning organization: learning ... structures and working practices [43] There is a transfer of learning from an example to one or more others Third, there is 'learning about learning' This entails people inlearning organisations taking...
... modulation of these neurons could further compromise their normal functioning In fact, we have recently found that, in both the PFC and anterior cingulate cortex, the expression of the mRNA for the NR2A ... paralleled the reduction inthe NR2A-expressing PV neurons Together these observations suggest that glutamatergic innervation of PVcontaining inhibitory neurons appears to be deficient in schizophrenia ... expression in PV neurons may, at least in part, contribute to the reduction inthe expression of GAD67 and PV andthe decrease inthe density of axon cartridges in schizophrenia [26,50-52] The expression...
... miR-9-1 and miR-30a can yield two mature miRNAs; the others yield one Furthermore, miR-7-2, miR-9-2, miR-9-3, miR-30b, and miR-30d are intergenic, andthe others are intronic in coding genes Using ... proteins (hnRNPs) [30], known to chaperone other RNA events The bioinformatic similarities involving motifs, though not yet investigated in vivo, are consistent with the hypothesis that the coordinated ... expression The findings of this study implicate a role for miRNAs in schizophrenia, and lead us to the hypothesis that there is altered processing of miRNAs during the miRNA biogenesis process in schizophrenia...
... acid (GABA) The disinhibition of dopamine-containing neuronsinthe ventral tegmental area (VTA) allows them to release dopamine inthe NAc and (via amygdala) in certain parts of the hippocampus, ... feelings of well-being andreward occur inthe meso-limbic system of the brain The natural sequence of events of the "brain reward cascade" leading to reward involves the inter-relationship of at ... Obesity and other reward deficient aberrant behaviors This concept is further supported by the more comprehensive understanding of the role of dopamine inthe NAc as a "wanting" messenger in the...
... Hypothermia was induced by 1,000 mL saline (4°C) and maintained by a cooling device (Icy catheter and CoolGard 3000; Alsius Corp, Irvine, CA, USA) that was introduced into the femoral vein According ... (suction rate, 200 mL/min; M-PRESTN; Datex-Ohmeda Inc., Helsinki, Finland) Total intravenous anesthesia (TIVA) was maintained by continuous infusion of to mg/kg/h propofol and 0.3 μg/kg/h sufentanil; ... damage, and inhibition of excitatory neurotransmitter release [4] There is growing evidence on the damaging nature of the inflammatory response following brain ischemia Various inflammatory cytokines...
... also includes learning methods and thinking methods Thus, through thelearning content, learners handle and apply learning content into practical life Methods of Teaching andLearning According ... attention to the management of the elements of the teaching andlearning process The elements of the teaching -learning process are inextricably linked with each other The goal of teaching -learning process ... for teaching andlearning process inthe credit-based learning approach, consists of teaching andlearning facilities, management software in training process, learning advisors, teaching equipment,...
... types: intrinsic and extrinsic motivation Tracing the word “intrinsic” down to its roots, it means “innate” or “within”, thus intrinsic motivation originates inthe individual itself Concerning learning ... speaking during the class hour were the activities motivating students Sub-question 2: What should we to improve the textbook? According to the teachers joining inthe study, the topics used inthe ... yearly and more interesting activities should be added to the textbooks 5.2 Implications The findings of the study implicate that: Inlearningthe speaking subject, the students seem to posses main...
... of other factors involved in speaking 1.3 Cultural factors inthe teaching andlearning of speaking skills in classrooms 1.3.1 What cultural factors influence on the teaching andthelearning ... with others The concept include a group’s way of thinking, feeling, and acting, and fixed patterns for doing certain things According to Thompson (1990:132), the pattern meaning embodied in symbolic ... effectively However, inthe thesis, the researcher wants to find out the attitudes, as well as the cultural awareness in teaching andlearning spoken English of the teachers andthe students of 10...
... the current situations of teaching andlearningthe English listening skill inthe Asemlink of International Language Center 3.2.1.1 The difficulties in teaching andlearning English inthe international ... solve difficulties inlearningthe listening skill 66 As it has been shown inthe finding and discussion part, the beginners found difficult inlearningthe listening skill since their own problems ... listening, speaking, reading and writing As an English teacher, with her own knowledge and experience in teaching, the author finds interested in studying the difficulties inlearningthe listening...
... of these ideas The result of thelearning process depends on the final product By contrast, inthe process approach the focus of teaching andlearning is placed on the process of writing rather ... writing? How useful are these activities to teaching andlearning writing skill? 1.4 Scope of the Study The study only focuses on investigating common activities used in writing teaching and their ... purposes of the study are: - to find out the challenges that teachers and 10th form students face with in teaching andlearning writing skill - to investigate how the writing sections inthe textbook...