shbg expression in breast and prostate cancer implications for hormone regulation
báo cáo khoa học: " Platinum resistance in breast and ovarian cancer cell lines Niels Eckstein" pptx
... Oxaliplatin (Eloxatin®) (Figure 1) are first-line anti -cancer drugs in a broad variety of malignancies, for instance: ovarian cancer, testicular cancer and non small cell lung cancer Cisplatin is inactive ... and testicular cancer when treated with cisplatin for which they show extraordinary Figure Structure formulas of platinum-complexes Cisplatin, Carboplatin, and Oxaliplatin Cis- and Carboplatin ... antracyclin Doxorubicin [39] However, bladderand prostate cancer cell lines with TRX overexpression are Cisplatin resistant and cross-resistant to Doxorubicin [40] Cisplatin resistance in ovarian cancer...
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Technology Gap and Efficiency in Cocoa Production in West and Central Africa: Implications for Cocoa Sector Development. ppt
... The WPS disseminates the findings of work in progress, preliminary research results, and development experience and lessons, to encourage the exchange of ideas and innovative thinking among researchers, ... agriculture in the early stages of industrialisation In West and Central Africa, agriculture has continued to play a dominant role in the provision of food, raw material for industries, employment for ... majority, and foreign earnings, which are used in financing development activities In the course of the last 40 years, industrial tree crops, notably cocoa, coffee, oil palm, and rubber, have dominated...
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báo cáo khoa học:" Quality of life measurement in women with cervical cancer: implications for Chinese cervical cancer survivors" ppt
... To be included in the study, a patient had to participate in the investigation in an informed and voluntary way The tenets of the Declaration of Helsinki were followed, and the study gained approval ... items and submit that structure to a confirmatory factor analysis We excluded binges and symptoms domains from the model because binges domain was an independent domain and the symptoms domain is ... patients being treated by four collaborating psychiatrists, experts in ED, working in three different mental health services in the province of Bizkaia, Spain Diagnosis of an ED was performed by...
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báo cáo khoa học:" Quality of life measurement in women with cervical cancer: implications for Chinese cervical cancer survivors" pdf
... domain including components of health status and co-morbidity; (2) Medical Factors domain including components of age at diagnosis and cancer characteristics; (3) Health Efficacy domain including ... specific issues in detail, such as what QOL domains are known to be important for Chinese women Regarding the issue of instrument selection, choosing an instrument for Chinese cervical cancer survivors ... acculturation, and interconnectedness; (3) Demographic domain including components of chronological age; and (4) Healthcare System domain including components of access to health care and satisfaction...
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the development of an instrument to measure individual dispositions towards rules and principles; with implications for financial regulation
... Scotland for providing support in the form of Seed-corn funding for some of the data collection involved in this PhD Finally, I would like to thank myself and God, for believing in myself and being ... scholarship and theory can shed light on the understanding of rules and principles in the accounting debate The on-going discussion on rules and principles in the domain of accounting, discussed in chapter ... Rules and principles in the accounting context are inherent in some of the characteristics of the rules and principles being defined in Law According to a number of prominent legal scholars leading...
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Báo cáo khoa học: "Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?" ppt
... cardiac morbidity in prostate cancer patients receiving androgen suppression therapy It was performed both in cancer patients and randomly selected individuals having had CT examinations for other medical ... choosing MeV In and individuals, 12 MeV were necessary to cover the pre-pectoral region adequately In the prostate cancer patients, MeV was appropriate in cases, MeV in cases, 12 MeV in cases and ... Distinct Moderate Distinct Moderate** Moderate** Moderate** Moderate** Distinct** Moderate** Moderate** * prostate cancer patient **when using the standard MeV beam in the absence of CT scan information...
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Báo cáo khoa học: " Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis" ppt
... established for rectal contouring in RT planning for prostatic carcinomas The length of rectum contoured has been defined in different ways by different authors Examples of these definitions include: ... entire prostate and seminal vesicles A 1-cm margin was added to the CTV to define the planning target volume (PTV) The treatment volume included an additional 0.7-cm margin for beam penumbra in all ... necessitating a major surgical procedure (laparatomy, colostomy, long stay in hospital); and grade = death Grades and rectal bleeding is defined as incidental or intermittent bleeding requiring no...
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Báo cáo khoa học: " The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications" pptx
... Her-2, Her-3, and Her-4) These receptors are composed of an extra-cellular ligand-binding domain, a hydrophobic transmembrane segment, and an intracellular tyrosine kinase domain Binding to EGFR ... regarding overall survival [29] Tyrosine kinase inhibitors (TKI) and RT In preclinical studies, when gefitinib was combined to RT, strikingly greater than additive effects were observed in vivo ... found in 148/155 patients (95%), with a wide range in interindividual variability In this study, EGFR expression was found to be independent from tumor stage or initial nodal involvement; in multivariated...
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Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt
... important in inflammatory responses involving IL-1β and MMP-3 and -9 in murine brain injury [26] This suggests that, although TNF-R1 levels remain unchanged and TNF-R2 gene expression is increased, ... 9:539-552 Alsalameh S, Amin R, Kunisch E, Jasin H, Kinne R: Preferential induction of prodestructive matrix metalloproteinase-1 and proinflammatory interleukin and prostaglandin E2 in rheumatoid arthritis ... expression of matrix metalloproteinase (MMP)-1, -3 and -13 and ADAM-TS4 (a disintegrin and metalloproteinase with thrombospondin motif 4) and ADAM-TS5, resulting in a net catabolic response Previous...
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báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc
... participated in the study design and carried out the FACS and microarray analysis JQ and JJ participated in the Colony-forming assay and performed human breast cancer xenograft assay XW and YD performed ... of these miRNAs, adding a new dimension to our understanding of the complex picture of BCSCs and assisting cancer biologists and clinical oncologists in designing and testing novel therapeutic ... miRNA processing and signal transduction (Additional file table S4) Discussion There is increasing evidence for the involvement of miRNAs in mammalian biology and breast cancer For instance, the...
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Báo cáo y học: " Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis" ppt
... increased in sJIA [29,30], and it has a prominent effect on erythropoiesis [31] by inducing hepatic expression of hepcidin and subsequent decreased intestinal absorption of iron and by inducing ... of individual hemoglobin concentration after the baseline sample and initiation of treatment in 12 patients with sJIA A significant increase was noted between baseline and time points 30, 60, and ... data of a non-overlapping cohort Studies by Allantaz et al [21] examined PBMC gene expression in patients with active and inactive sJIA and other diseases, including bacterial infections, systemic...
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Báo cáo y học: "Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions" doc
... features of breast cancer patients, aiming to examine its clinical value for the discrimination of the cancerous from non-cancerous breast lesions Materials and methods Breast tissue specimens and study ... the expression analysis of KLK5 in cancerous and benign breast lesions, targeting the evaluation of the clinical use of KLK5 expression for the discrimination of the malignant from the non-cancerous ... be carried out, in order to reinforce the significance of KLK5 expression analysis in breast cancer patients and to reveal the molecular alterations that occur during breast carcinogenesis Author...
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Báo cáo y học: "Can a single model explain both breast cancer and prostate cancer?" pps
... binding of T to mAR and DHT to iAR In order to determine the best protocol for preventing BC and PC, the HTLD, HTHD, and LTHD protocols should be examined for their efficacy in increasing RD for ... chance of developing PC for men BRCA2 mutations result in an increased chance of developing BC for men and for women and an increased chance of developing PC for men [24] According to the extended ... account for the observed increase in PSA for those men taking 5AR2 inhibitors Pharmacological amounts of genistein induced apoptosis in PC cell lines by a process independent of its binding to...
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Báo cáo y học: "Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring" doc
... therapeutics for prostate cancer candidate predictor of efficacy in both prostate and breast cancer Finally, the observed sensitivity to dasatinib of prostate cancer cell lines with expression ... expression with dasatinib sensitivity in cell lines, and being a target of the drug, EphA2 appears to be a strong candidate biomarker for dasatinib in prostate cancer Down -regulation of uPA expression ... treatment for prostate cancer It is noted that imatinib, which inhibits three of these targets, including Abl, c-kit and PDGFR kinases, showed minimal efficacy in early clinical testing with a...
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Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
... cell and tumor signatures are found in human prostate cancers containing a minimum Gleason score pathology Distinctive stem cell and tumor signatures are found in human prostate cancers containing ... matrix-receptor interaction Discussion Despite advances in both screening and in surgical treatment, the long-term prognosis for patients with hormone relapsed prostate cancer remains disappointingly poor ... S100 calcium binding protein A3 S100A3 1.92 1.55 Chromosome 17 open reading frame 27 C17orf27 1.63 1.80 RAS and EF-hand domain containing RASEF 2.31 1.71 Integrin, alpha V (vitronectin receptor,...
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Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
... long chain fatty acids (Elovl3), type iodothyronine deiondinase (Dio2), homeobox C9 (Hoxc9), insulin-like growth factor binding protein (Igfbp3), dermatopontin (Dpt), and b-actin are showed in Table ... standard deviation inflammatory response and IR development, were examined in mice As shown in Figure 3, PM 2.5 exposure induced a marked increase in macrophage (F4/80+ cells) infiltration in ... reduced in both eWAT and iBAT in response to PM2.5 exposure Recent studies have implicated PM2.5 in increased adipose inflammation and insulin resistance [11,12], and epidemiological studies indicate...
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Evaluating impacts of air pollution in China on public health: Implications for future air pollution and energy policies pptx
... in Zaozhuang which supplies 2% of total energy needs (10% of the energy needs in the residential and commercial sectors) in three surrounding municipalities—Jining and Linyi in Shandong Province ... that the VSL for Chongqing is representative of China Given that the in ation rate in China between 1998 and 2000 was À1% and that the per capita income in China is projected to increase from ... Leksell and Rabl (2001) for China Note that the China coefficient shown in Leksell and Rabl (2001) is for age 35 and above However, using the same coefficient for the study population age 30 and above...
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Health-related quality of life of elderly living in nursing home and homes in a district of Iran: Implications for policy makers pdf
... studies conducted by Lee and Shinkais (2003) & Mokhtari and Ghasemi (2011) Also we found that residents living in nursing home had lower score in all domains of SF-36 and its domains As others mentioned ... responDiploma dents were informed about the purpose of the study Diploma and 14.61±4.67* 14.36±5.05* 14.78±4.68* and their consent was obtained before initiating the above interview R (adjusted) ... entered and analyzed after two times revision using the Statistical Package for Social Sciences for Windows version 16.0 (SPSS Inc., Chicago, IL, USA) Means and standard deviations were computed and...
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Nutrition, Exercise and Prostate Cancer potx
... exercise Key Points to Remember Avoiding muscle loss and/ or gaining muscle through increased protein intake and exercise can help in achieving and maintaining a healthy body weight Increase intake of ... with prostate cancer, including heart disease and diabetes 18 Building Strong Muscles Avoiding the muscle loss common in aging, inactivity, and hormonal therapies and/ or gaining muscle through increased ... for cancer and stimulates production of insulin, which is linked to an increased risk of diabetes, heart disease, and prostate cancer Cutting back on sugar intake, maintaining a healthy diet, and...
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Báo cáo khoa học: Differential gene expression in periportal and perivenous mouse hepatocytes potx
... localized in the periportal area, namely ornithine transcarbamylase (EC 2.1.3.3), argininosuccinate synthetase (EC 6.3.4.5), argininosuccinate lyase (EC 4.3.2.1), and arginase (EC 3.5.3.1), showing ... protein level) RNA periportal, protein equally distributed Fig Zonal differences in expression of genes encoding enzymes and other proteins involved in intermediary metabolism Perivenous expression ... shown in detail in Fig and additionally shows the gradients in oxygen tension, hormones ⁄ growth factors, and b-catenin signaling that have been suspected to in uence zonal gene expression in the...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25