... the helix–loop–helix EF-hand domain from STIM1, the helical content of the engineered protein CD2.STIM1.EF increased, indicating that the inserted EF-hand motif at least partially maintains the ... as CD2.STIM1mut) resulted in at least a 12-fold decrease inthe Tb3+-binding affinity (Kd > 2.1 mm, Fig 2B), suggesting that these key residues are essential for metal binding The direct binding ... the apparent dissociation constant by Eqn (1) By assuming that the sample is saturated with Tb3+ at the starting point of the competition, the Ca2+-binding affinity is further obtained using the...
... was available until now, as other putative lysine decarboxylase-encoding genes occur inthe S coelicolor genome (e.g SCO2017) As one of the iron boxes was located inthe upstream region of the ... the biosynthesis of desferrioxamine B in S pilosus indicated that the first step inthe desferrioxamine biosynthesis is the decarboxylation of lysine by a lysine decarboxylase encoded by the desA ... start point is indicated as +1 (bent arrow) The1 9-bp palindromic region, which contains the repressor-binding site, is boxed, and the ribosome-binding site is underlined The ATG is shown in bold...
... RAF), another shuttling kinase, is involved inthe regulation of translation initiation by activating p70 S6 kinase and phosphorylating eIF-4E-binding protein [52] When FRAP was restricted to the ... domain are shown The protein kinase A (PKA)dependent phosphorylation sites, Ser577 in SIK1 and Ser587 in SIK2, are indicated in bold The basic residues in domain 3B are indicated by underlines The ... expressed in Y1 cells The wildtype SIK1 (Full) contains amino acids 1–776 The kinase domain (27–278) is inthe N-terminal half, whereas the region essential for nuclear localization (573–631) is in the...
... a big economy such as Italy if the latter were to go downthe drain Instead, the main reason for the jitters of the investing public lay inthe lack of certainty concerning the bond market A second, ... reversed inthe banking industry The same is true of the reasons for saving the biggest clods from their self-caused wounds Inthe wake of the financial flap, the deadbeats balked at fulfilling their ... broke down during the financial crisis of 2008 The meltdown caused a whale of a blowout inthe financial forum as well asthe housing market and the entire economy To round up, the arguments in...
... Training the handicrafts is done by method of handing down Nowadays, this method has many changes and more diverse, in which, combination between the opening of training classes and the teaching ... specialize in producing the handicraft products; they specialize in manufacturing the goods for production and life; - they specialize in producing goods of the consumption service; they specialize in ... and associated with certain conditions of nature, market, etc The handing down, training the handicraft are basis forms in these villages, determinant is artisans, techniques and trade secrets Their...
... standard inthe hopes that it becomes the industry standard,” says Mr Keough of Yankee Group “It’s not really developing consistency across the industry Increasingly we’re seeing industry groups ... as servicing and repairing 18 heating systems, installing energy micro-generation and fitting insulation Indeed, by installing smart meters, the company generates masses of data that it can then ... stock levels in vending machines, for example Telecoms operators need to continually develop their own business models and customer offerings Machine-to-machine and the Internet of things in 2012:...
... to continue as a going concern.42 Under the going concern assumption, an entity is ordinarily viewed as continuing in business for the foreseeable future with neither the intention nor the necessity ... are reasonable if it has invested in similar instruments Using the Work of an Expert The process of developing the overall audit strategy helps the auditor to ascertain the nature, timing and ... evidence obtained asthe basis for forming an opinion on the financial statements Forming an opinion as to whether the financial statements give a true and fair view or are presented fairly, in all...
... is ordinarily viewed as continuing in business for the foreseeable future with neither the intention nor the necessity of liquidation, ceasing trading or seeking protection from creditors pursuant ... liabilities, and obtain refinancing (if necessary) inthe normal course of business In assessing whether the going concern assumption is appropriate, management takes into account all available information ... Considered in Making a Going Concern Assessment viewed as a guarantee that future events or conditions will not result inthe entity ceasing to continue as a going concern Ordinarily the applicable financial...
... taken based on language inthe grade level definitions inthe law alone The language inthe title definitions is to be interpreted within the context of all the applicable grading criteria in this ... mathematics, and engineering to the study of metals Metallurgy is the art and science of extracting metals from their ores, refining them, alloying them and preparing them for use, and studying their properties ... planning and carrying out the assignments, resolving most of the conflicts that arise, coordinating the work with others as necessary, and interpreting policy on own initiative in terms of established...
... DISCUSSION The pattern of the ring-width series was very similar for all sample sites on the southern as well asthe northern slope The same was true for the latewood However, there was no density ... 1980, a long-lasting period of severe growth depression occurred inthe southern-slope chronology The trees started to recover as recently asthe late 1980s From 1974 on, an increasing number of ... taken for both the measurement of the annual increment and the wood density The coring was done parallel to the slope to avoid compression wood were The tree-ring widths were measured with an...
... components based on theselection pressure applied The estimator of R is then a function including S, which is not the case inthe standard methods of analysis of selection experiments The question ... ONE-GENERATION SELECTION EXPERIMENTS, ASSUMING PRIOR VALUES OF THE VARIANCES INTHE MODEL As early as 1979, Thompson had pointed out that the responses derived from mixed models include information ... dependent the animal model estimators are upon the heritability assumed inthe model Excluding extreme deviations of h from h) , the estimators will generally increase with increasing 2 value of h The...
... animals for the exclusion of incorrect pedigrees were conduc- Haplotyping The method used inthe present study to determine the haplotypes was based on deducing linkage phases involving Hal and ... was inferred from various informative matings Assuming that the gene order is Phi-Hal-H as suggested by Rasmusen (1981) and not Hal-Phi-H, the first recombinants of the first matings given in ... parents These were used to determine the order of the loci Results TableI provides a summary of recombinations involving the Hal and Phi loci recovered in progeny from matings in which one parent was...
... [4] In these cases, the mass itself was contained within a fascial covering Presumably, the mass effect became more pronounced over time asthe slow-growing lesion increased the pressure on the ... defect in his dorsal forearm fascia originating within the most proximal portion of the extensor group There was no invasion of the local muscle tissue and his elbow capsule was intact and uninvolved ... To the best of our knowledge, this is the first report of a lipoma extending through the posterior fascia covering the extensor compartment presenting as a posterior elbow mass In this case, the...
... collect data to assess the status of the management training of current EM asthe basis for proposed solutions appropriate for the training management for these objects at the Ho Chi Minh National ... importance of the training of political theories for ethnic minority staff inthe present context The reality requires them to have theoretical thinking and the right understanding of the scientific ... service for the training activity M GV HV QL L N P Đ M: Training Objectives GV: Training Forces HV: Trainees N: Training Content P: Training Methods Đ: Conditions of Training 1.4.2 The approach...
... synchronization Developing the teaching staff is planning, organizing, instructing, testing and assessing every stage from planning, selecting, employing, training, fostering, testing, assessing and treatment ... synchronously the solutions for dealing with planning, selecting, employing, training, fostering, inspecting, testing and setting up policies 8.2 Inthe process of carrying out the solutions, ... framework of the thesis Based on the theoretical framework, the thesis analyzes and assesses the reality of teaching staff inthe upper secondary schools and developing the teaching staff inthe upper...
... serving multi-level training mission is weak and insufficient - Training scale tends to decrease, fast decrease inthe low-level training University training scale is relatively stable (as shown ... is the first time the thesis has examined thecurrent status of school types to find out its difficulties and shortcomings and their own scientific way assisting the universities under the Ministry ... its effect on managing the staff 3.6 Investigating and experimenting the solutions 3.6.1 Investigating the feasibility of the assessing set of staff managing standards Making survey to managers...
... education inthe universities inthe Mid-Central provinces today must be always based on the principle of ensuring the proletarian Party, serving the mission of the Party, under the leading of the Party ... law teaching staff The thesis proposed some basic measures: Planning and developing law teaching staff; Increasing the quantity of law teaching staff; Developing quality of law teaching staff; ... For the provinces, cities inthe Mid-Central area: The provinces and territories need to focus on directing the construction of lecturers staff; increasing funding for the construction of infrastructure,...
... training and fostering with the contents such as: Identifying the demand of training, developing the training plan, managing the implementation and assessment of trainning, and training, fostering ... executing of superiors’ guidelines, but also meeting the requirements of implementIng political tasks at training and fostering institutions inthecurrent period - Well developing the fostering ... OPS fostering management in order to form the practical basis for suggesting managing measures for fostering OPS at the Ministry’s TF institutions inthecurrent period 2.2.1.2 Areas, objects...
... inthe future; The thesis has found the situation of the activities of the vocational education management, highlighting the situation fromthe practical activities inthe centers of Continuing ... the United States inthe 1900s, Lahy’s work in personnel selection Lahy in France in 1910; Gemelli’s efforts intheselection of personnel in Italy in 1912, and the focus on the vocational education ... education; the contents of the vocational education; the method of the teaching; the teaching facilities; the forms of the organization, and the assessment of the learning outcomes The each element...
... influence them to things they would not ordinarily And convincing them without raising the least hint of suspicion The typical shower of presents from relatives and from people who attended the ... for making requests, whom they routinely get requests from, under what conditions they release the desired information, and the lingo and terminology used inthe company The social-engineering techniques ... adding or removing customer phone services such as custom-calling features I called posing as a manager fromthe business office It was easy to convince the clerk to add call forwarding to the...