recent data on the structure and function of neurons in the cerebral cortex
Báo cáo y học: " The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells" potx
... analysis and assisted in the writing CIØ carried out the isolation and characterization of the cells GIN participated in the oxygen measurements, as well as in the determination of glucose and lactate ... reagent Authors' contributions IM and BS conceived of the study IM carried out most of the experimental work and the writing AW and DGL participated in the determination of fenestration parameters, ... ultrastructural characterization of the endothelial cell in the rat liver sinusoid under normal and various experimental conditions, as a contribution to the distinction between endothelial and Kupffer cells...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... obtained indicate that the KIND2 domain is necessary and sufficient for the targeting of v-KIND to dendrites of neurons To investigate the MAP2-binding characteristics of the KIND domain protein ... in the central domain of MAP2 contain the v-KIND binding core module MAP2 consists of three main structural domains: the cAMP-dependent protein kinase regulatory subunit RII binding domain, the ... in the KIND2 domain of v-KIND contain the core MAP2 binding module To identify the core MAP2-binding site within the KIND2 domain (amino acids 456–620), we analyzed five EGFP-fused KIND2 domain...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... age and size at first reproduction, number and size of offspring, inter-clutch interval, and juvenile and adult survival The effects of changes in the magnitude of each of these traits on the others ... different kinds of organisms, depending in part on the form in which they are stored (e.g structural carbon in plants, and calcium and phosphorus in the shells of molluscs and the bones of vertebrates) ... is the traditional Lindeman efficiency that has been the subject of so much discussion and investigation in ecology It is apparent from inspection of the above equations that the M3/4 scaling of...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... domain of each subunit contributes to the formation of the hydrophilic pore ACh binding protein has structural and functional homology to the extracellular ligand binding domain of the nAChR, and ... tissues The a4/7-conotoxins are the most common nAChR antagonists found in cone snail venoms Identification of further selective peptides, together with the investigation and understanding of their structure- activity ... application and served as an important tool in the elucidation of nAChR subtypes and function in the dopaminergic system The following will focus on the investigation of presynaptic nAChRs on dopaminergic...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... the interaction at the atomic level and understand the role of the threonine side chains in ice binding The contradiction between the higher activity demonstrated by the longer insert AFP isoforms ... in the TXT motif are conserved, and that in solution these waters could be found on the ice-binding face Fig Bound water molecules extend the ice-binding face of insect AFPs The position of the ... isoform CfAFP-501 using the main chain of residues Thr23fiAsn90 in isoform 337 and residues Thr54fiMet121 in CfAFP-501 (B) Overlap of isoforms 337 and 501 using the main chain of residues 4–33 in...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... determination The existence of two distinct sets of resonances for the minidomain allowed the determination of two families representing the two conformational states of the solution structure of the ... NMR structure and function of the eRF1 C-domain codon recognition are in accord with the hypothesis that the C-domain could be involved in the regulation of translation termination As Asp359 and ... detected Therefore, the sizes of the relative populations and possibly the rate of conformer interconversion are sensitive to the environment of the domain For the great majority of the residues in the...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx
... explanation for these results may be that the reaction of SDTG at the binding site of one subunit changes the conformation of the other subunit, thereby completely abolishing reaction of SDTG with the ... solutions and the presence of electron-rich nitrogen sites on the triazine ring, which increase the capability of forming additional hydrogen bonds with amino-acid residues within protein binding ... phosphate buffer, pH 7.0, on the basis of the SDTG concentrations determined from the primary amine content Determination of the stability of SDTG The rate of decomposition of SDTG in a buffer identical...
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Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot
... rates of oxygen consumption The maximum rate of oxygen consumption was induced by the addition of 50 nM SF6847, and this value was utilized as the noninhibited rate of oxygen consumption Inhibitory ... effects of DiS-C3(5) at low concentrations on the progression of intrinsic oxygen consumption by mitochondria might reflect induction of the PT by endogenous Ca2+ So next we examined the validity of ... Inhibitory effects of a low concentration DiS-C3(5) on the Ca2+-induced PT To examine the effects of DiS-C3(5) on the Ca2+induced PT, we measured its effects on the oxygen consumption of mitochondria...
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Báo cáo khoa học: Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2 pdf
... B-factor in one of the active sites of a tetramer and, as in our P212121 structure, they could see a few more residues of the loop, including the lysine pointing towards the active site The binding ... predicted in the mutant First, there is an increase in the negative charge in the active site and, second, breaking the salt bridge would alter the quaternary structure of the protein and therefore the ... determine the nature of the inhibition Surprisingly, both citrate and isocitrate acted as noncompetitive inhibitors (Fig 3), lowering the Vmax but not the KM of the lactonization reaction The KI...
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structure and function of the arabic verb
... indicative, in our opinion, of the adequacy and the basis of this orientation, on the one hand, and the destiny of linguistics, on the other hand Of course, these implications might be too strong, but ... The shift between the development of modal logic since the beginning of this century (Von Wright 1951, among others) and the special interest in the notion of Modality in linguistics during the ... Arabic on one end, and SA on the other end Each end contains the defining characteristics of each form, with various degrees of interaction in- between Standard Arabic is also in constant interaction...
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Báo cáo khoa học: "Comparison between the structure and function of chloroplasts at different levels of willow canopy during a growing season" ppsx
... availability of excitation energy in the canopy and not by altered organization of thylakoid membranes Later in the growing season, the chloroplast ultrastructure acclimated to decreased light (Fig 2B) and ... to ageing, since the area of plastoglobuli of chloroplast area increased (data not shown), which is known to be an indication of ageing (Hudak, 1981) .The pattern of thylakoid organization at ... a tion was found between negative correla- N P and the ratio of the length of appressed to nonappressed thylakoid membranes (Fig 2A) and between the ratio of the length of appressed to non-appressed...
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Báo cáo y học: "A comparative approach for the investigation of biological information processing: An examination of the structure and function of computer hard drives and DNA" doc
... between the genetic information encoded in the cell’s DNA and its intracellular information-processing infrastructure (RNA and proteins) The structure and function of this information-processing ... challenge of characterizing cellular information processing arising from biology’s use of poly-functional components in the name of “economy.” The conversion of DNA information into mRNA information ... representation of information in the form of Qbits on the DHD The generation of various types of RNA from the DNA code convert the coded information into a poly-functional format for use throughout the...
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Structure and function of methyltransferases from antibiotic resistance bacteroides of human intestine and a study on nm ng with cam
... consist of well-conserved AdoMet-binding domains responsible for cofactor binding and methylation; and a second highly variable substrate-binding domain responsible for the substrate binding The ... intrinsically unstructured proteins and explains how the unstructured proteins gain structure upon binding with its partners Chapter provides the conclusion and future direction for part II of ... divided into two groups The first one comprises a benzoquinone termed ubiquinone or coenzyme ubiquinone The second group contains 15 naphthoquinones – menaquinone and demethylmenaquinone (DMK)...
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... regions of active genes in human T cells [124] In a study in yeast, mutations were introduced alone or in combination in lysines 5, 8, 12 and 16 in the gene for histone H4 [125] Of these, the only ... transcription elongation in mammalian cells [153] Phosphorylation of histone H3S10 by Pim1 kinase enables the recruitment of both MOF and P-TEFb via interactions involving the adaptor protein 14-3-3 and ... both the disruption and ejection of nucleosomes within the enhancer and the mobilization of nucleosomes in the flanking sequences AP-1 function is dependent upon the SWI ⁄ SNF family protein Brg1...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... domain, where the C-terminal portion of one saposin is linked to the N-terminal portion of the other saposin Hence, the PSI is not a true saposin but a swaposin [25,38,42] (Fig 3) The functions of ... C-terminal domain in red (B) Ribbon representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red) (C) Model structure of the PSI ... cDNA of an AP was cloned from Chlamydomonas Fig The ‘saposin fold’ (A) Ribbon representation of the structure of NK-lysin, a saposin-like protein [26] The N-terminal domain is shown in blue and...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... result in the truncation of the TLP at the N-terminus This truncation has no effect on amino acid residues known to be involved in the function of the protein, but result in the deletion of the ... on interactions of the N-terminal region of OHCU decarboxylase with the receptor kinase brassinosteroid-insenitive-1, rather than interactions made by TLP Furthermore, their conclusion that the ... recent findings regarding the identification and distribution of TLP genes in nature, the structural and functional characterization of the TLP from various organisms, and the evolution of TLP and transthyretin...
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Báo cáo khoa học: Structure and function of KH domains docx
... in and across the groove between the a1-helix and a2helix and the b2-strand of KH1 Intimate contacts between protein and RNA continue across the cusp of the KH1 and KH2 domains C46 binds to the ... orientation, in the groove between the a1-helix and a2-helix plus the GXXG loop on one side, and the b2-strand and the variable loop on the other The center of the groove is hydrophobic, and the edges ... sidechains on the protein and the phosphate backbone of the nucleic acid Poly(C)-binding proteins Poly(C)-binding proteins (PCBPs) contain three type I KH domains, which appear to function independently,...
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Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx
... within the ATP-binding subdomains, indicating a common structure of the ATPbinding sites of the two enzymes Interestingly, five of the six cysteines of GlcNAc kinase had an equivalent cysteine in ... three-dimensional model of glucokinase was used [23] Based on the sequence alignments of glucokinase and GlcNAc kinase and the common ATP-binding domain, the GlcNAc kinase was fitted into the glucokinase ... pocket in the adenosine subdomain and the sugar pocket on the opposite side within the b-sheet II [25] The positions of the cysteines of GlcNAc kinase are displayed in Fig 5B Cysteines C211 and...
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effect of processing parameters on pore structure and thickness of anodic
... the molecules once pass into one end (inner) of the pore would only come out from the other end (outer) of the pore without diffusing out from the middle of the pore-tunnel The relationship of ... separation application as it helps to maintain the mechanical integrity of the tube during processing, handling and filtration Conversely, a smaller tube wall thickness strengthens the rate of fluid ... causes a decrease in nanohardness The decrease in nanohardness confirms the domination of dissolution rate as the anodization continues As mentioned previously, the increase in oxidation rate is believed...
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Báo cáo khoa học: F1 – Structure and Function of Motor Proteins pot
... growing filaments They also confirm the suggested role of D-loop in stabilization of both the longitudinal subdomain 2/1 contacts and of the cross-strand contacts in F-actin F1-012P The dynein light ... A structure of a truncated version of the reverse direction myosin motor, myosin VI that contains the motor domain and binding sites for two calmodulins Surprisingly, the structure reveals only ... change on the secondary structure of blg-A upon interaction with concentrations of 15.54 and 35.8 mm of Pb2+, while far CD studies show considerable change in the secondary structure of blg-B by increasing...
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