quantification of f2 isoprostanes to assess the role of oxidant injury in human diseases
Báo cáo khoa học " Structure elucidation and antioxidant activity of a novel polysaccharide isolated from Tricholoma matsutake " ppt
... As is the absorbance in the presence of the sample and H2 O2 , A0 is the absorbance of the control in the absence of the sample and H2 O2 , and A is the absorbance only in the presence of the H2 ... cm−1 in the IR spectrum (Fig 1) was due to the hydroxyl stretching vibration of the polysaccharide and as expected they were broad The bands in the region of 2923.62 cm−1 were due to C–H stretching ... anomeric proton signals at ı5.182, ı5.107, ı5.060 in the H NMR (400 MHz) spectrum According to the literature [24], the resonances in the region of 98–106 ppm in the 13 C NMR (200 MHz) spectrum of TMP-A...
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Báo cáo vật lý: "Evaluation of In Vitro Antioxidant Activity of 5H-dibenz[b,f]azepine and Its Analogues" ppt
... with a spectrophotometer An identical experiment was performed in the absence of the compound to determine the amount of lipid peroxidation obtained in the presence of inducing agents as a control ... (a) The presence of the methoxy group in the seven member ring may enhance the stability of the nitrogen centred radical due to the electron conjugation effect The absence of N– Evaluation of In ... hydrogen atoms, in compounds (a) and (d) may contribute to the lipid peroxidation activity The presence of the methoxy group at the 10th position of the member ring addition to the free N–H group in...
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Báo cáo y học: "Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent" pptx
... investigated the antioxidant potential of TPBIA, since there are some reports concerning the role of free radicals in TD [7] Therefore, it becomes interesting to design compounds that maintain antipsychotic ... antagonist in the central nervous system The tosyl group in TPBIA, which plain was found to be perpendicular to that of the indole ring in its low energy conformation (Figure 4) [24] is important to the ... blood-brain barrier [26], which could explain why other studies failed to confirm these results [6] Therefore we considered interesting to investigate the antioxidant potential of the synthesized...
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Báo cáo y học: "Antioxidant activity of tuberosin isolated from Pueraria tuberose Linn" pot
... whether it is directly inhibiting the activity of iNOS enzyme or it is suppressing the synthesis of this enzyme To target this question, we explored the effect of tuberosin on iNOS protein in ... exposed to LPS Interestingly, our data show that tuberosin significantly inhibited the iNOS protein in western blot analysis The results suggested that tuberosin is inhibiting the expression of iNOS ... system They may activate the inflammatory cascade, resulting in initiation of various degenerative diseases and autoimmune disorders [15] Therefore, these antioxidants have variety of other biological...
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Antioxidant activity of essential oils
... taken to minimize the loss of free radical activity of the DPPH radical stock solution.24 Percent inhibition of the DPPH radical by the samples was calculated according to the formula of Yen ... was used to determine the antioxidant lipid activity of volatile compounds contained in the essential oils of the spice plants The Rancimat worked on the following principle: A solution of different ... h Determination of Ferric Reducing Antioxidant Power (FRAP Assay) The total antioxidant potential of a sample was determined using the ferric reducing ability of plasma (FRAP) assay of Benzie...
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Evaluation of the antioxidant activity of scutellaria baicalensis and its constituents in diabetic rats
... haemotoxylin staining The intact Langerhan Islets explain the increase in plasma and pancreatic insulin contents despite the administration of STZ Scale bars indicate 100µm 10 Figure 4.1 The ROS ... introduction of antioxidants into the diet Phenolic antioxidants in the diet have been shown to be remarkably effective in delaying or preventing the onset of chronic inflammatory diseases (Finkel, 2000) ... islets of Langerhans of healthy dogs The research by Banting and Best progressed on to the isolation of insulin from bovine pancreases at the University of Toronto in Canada This led to the availability...
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Nghiên cứu về hoạt tính chống oxy hóa của các cây thuộc African Antioxidant Activity of African Medicinal Plants
... activity in vivo in rats [91] Bergenin has been reported to protect against 2,4-dinitrophenylhydrazine (DNPH)-induced hepatotoxicity and toxicity to red blood cells in rats The stem bark extract of ... plant belonging to the family Myrtaceae It is used as a remedy for sore throat and other bacterial infections of the respiratory and urinary tracts Essential oils of the leaves are used in the treatment ... that there is an inverse relationship between the dietary intake of antioxidant-rich foods and the incidence of human disease [19] However, synthetic antioxidants, such as butylated hydroxytoluene...
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Báo cáo y học: "Pravastatin Provides Antioxidant Activity and Protection of Erythrocytes Loaded Primaqe"
... after incubation with primaquine is due to interaction of ROS with NPSH oxidizing them On the contrary, statins have ability to inhibit the production of ROS as well as maintains the antioxidants ... capacity of antioxidants enzymes to maintain and keep up the membrane integrity [34] The major alteration in the shape of erythrocytes is the spherocytes formation in the presence of primaquine These ... that in vitro exposure of RBCs to oxidants resulted in damaging of protein in addition to increase PCO formation [27] This may suggest that oxidant drugs increase free radicals production in red...
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Báo cáo hóa học: "Effects of Pin-up Oxygen on [60]Fullerene for Enhanced Antioxidant Activity" pptx
... mixture of fullerene oxide C60On.1 The dotted line indicates the value in the absence The C60On, instead of C60O2 due to the difficulty in availability, was used to investigate the effect of the number ... C60On The slope of each linear regression line corresponds to the relative radical scavenging rate constant krrs relative to that of b-carotene The dotted horizontal line indicates the value in the ... one of the common methods used in the field of food chemistry for evaluating antioxidant activity The method is based on the discoloration of the yellowish color of a b-carotene solution due to the...
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Báo cáo y học: " Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system" pdf
... of Nrf2 protein to the nucleus, and the gene and protein Page 12 of 15 expression of Nrf2-activated antioxidants Although the focus of the present study was directed toward the Nrf2 system, the ... expression of proinflammatory cytokines [50] The results of the present study indicate that the mixture of natural oils was capable of reversing the nasal inflammatory response to ozone exposure in healthy ... shown to stimulate the influx of PMNs into the airway lumen as early as hr following exposure [47] suggesting very rapid initiation of pro-inflammatory signaling In the present study, the effectiveness...
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anthocyanin – study of extraction from basella rubra l and verifying antioxidant activity, application in identificating di sodium tetra borate in food
... Figure The colored change of Anthocyanin among pH range The color of Anthocyanin solution changed through the pH range from to 14 as shown on the figure The rising of pH from an initial point of to ... proportional to the decrease of Anthocyanin concentration The reason of decreasing AA% was the decline of 14 Anthocyanin molecular through dilutions The result of antioxidant activity was shown in table ... applied as an indicator to identify the present of borax in food through the color change In total, this thesis aim to: study of extraction from Basella rubra L and verifying antioxidant activity,...
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Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"
... 491-9 Huang S, Shao G, Liu L The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression ... PR domain of human retinoblastoma protein-binding zinc finger protein (RIZ1) Int J Mol Sci 2008; 9: 943-50 21 Chen L, Ling B, Alcorn J, Yang J Analysis of the expression of human N-myristoyltransferase ... is involved in the early tumorigenesis of hepatocellular carcinoma Histol Histopathol 2008; 23: 1171-5 Liu L, Shao G, Steele-Perkins G, Huang S The retinoblastoma interacting zinc finger gene...
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ANALYSIS OF MICROBIAL COMMUNITY STRUCTURE AND IN SITU ACTIVITY OF NITRIFYING BIOFILMS
... became dominant populations in the autotrophic nitrifying biofilm after switching to the synthetic nutrient medium Development of NH4+-oxidizing Bacterial Populations in Biofilms To visualize the population ... demonstrates the sequential oxidation of NH4+ and NO2- in the oxic biofilm strata, that is, the active NH4+-oxidizing zone is located in the outer part of the oxic biofilm, whereas the active NO2 oxidizing ... distributions of in situ nitrifying activities were determined The relationship between the spatial organization of nitrifying bacterial populations and the in situ activity of these populations within the...
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Photocatalytic bactericidal activity of silver-sensitized titanium dioxide on Micrococcus lylae
... efficiency of Ag2 However, mixing was not the limiting factor for the bactericidal action of Ag1 and pure TiO2 since increasing the stirring speed did not seem to enhance the bactericidal activity of the ... addition to the effect of photocatalyst concentrations, the effect of stirring speed in bactericidal efficiency was investigated (Fig 4) It was found that increasing the stirring speed from 300 to ... condition of fixed UV intensity, adjustment of photocatalyst concentration is a critical step for maximizing the reaction efficiency but minimizing the shading effect Effect of stirring speed In addition...
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Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf
... PFI1625c), or insulysin and pitrilysin [32], possibly involved in the processing of apicoplast protein leader sequence Inhibition of any of these activities could contribute to MA interference in the maturation ... h in the presence of MA (100 lM) were used to obtain an extract of parasite proteins and Wright’s stained thin smears for monitorization of the infective stage (A) Western blot of the protein ... explained either by the direct inhibition of falcipain [38] or by the indirect effect on the functionality of the vacuole as a result of the accumulation of partially hydrolysed peptides, leading...
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Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt
... Acquisition of the MGD cofactor by TorA in the cell cytoplasm is an essential pre-requisite to translocation of this protein [10] The torD gene product is involved in cofactor loading into TorA [11–18], ... Tat proofreading chaperone, binding directly to the TorA twin-arginine signal peptide [5,19,20] TorD belongs to a family of peptide-binding proteins specifically dedicated to molybdoprotein assembly ... Dimerisation of the Shewanella massilia TorD protein is driven by ‘domain-swapping’ in which the N-terminal domain of one protomer packs 512 onto the C-terminal domain of a second protomer (and...
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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... pathway The key event in the mitochondrial pathway is the release of proapoptotic factors from the mitochondrial intermembrane space into the cytosol, resulting in the downstream activation of a ... death receptor-mediated apoptosis in many cell systems [16,17] The BH3 domain-only proteins are a subfamily of the Bcl-2 family involved in the initiation of apoptosis through the mitochondrial ... produced (Fig 1D, lane 2) In the presence of lactacystin, a significant increase in the amount of tBid–GFP present in the extract, both in control conditions and in the presence of FLAG–Itch, was observed...
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Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... observed with the use of lm recombinant human calpastatin domain (CSD1, calpain inhibitor protein), 0.5 lm ovocystatin (cysteine protease inhibitor protein), 20 lm MG-132 (proteasome inhibitor), 20 ... domains of calpain affect each other to maintain an interacting interface seems attractive However, at present, we have no clue as to whether MIM1 and MIM2 bind to only one MIT domain or bind to ... sites underlined) The amplified cDNA fragment was first inserted into the Zero Blunt TOPO PCR Cloning vector (Invitrogen), and the EcoRI fragment was then inserted into the EcoRI site of pCMV3xFLAG-B...
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... for the low activity of the Y74W* mutant: (a) introduction of the bulkier residue at the interface in place of a tyrosine may destabilize the dimer, resulting in a shift in the equilibrium towards ... only critical for the stability of the dimer, it may also be involved in maintaining the integrity of the active site These results clearly suggest that the dimer interface in the Y74W* mutant ... hydrogen bond with the backbone CO of F102 Furthermore, the orientation of the side chain of the two residues brings the guanidinium plane and the aromatic ring of F102 into close proximity, with an...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25