... using the mapping software Crimap [26] Model and test statistic Mixed model Our model includes sex as a fixed effect and polygenic and QTL genotypic effects as random effects Random effects can be ... residual polygenic variance and allow a more accurate estimation of QTLs and polygenic gene effects It is also important to consider the potential multiple effectsof a QTL For instance, pleiotropy ... polygenic effectsand a unit matrix, respectively Q1 and Q2 are IBD matrices for variance-covariance of the genotypic effect at QTLs and 2, respectively Polygenic and residual variances are σ2u and...
... 41 3.5 Graph of Tb.N 42 3.6 Effectsof single and combined treatments 44 3.7 Graphs of BV/TV and SMI 45 3.8 Graphs of Tb.Po and Tb.Th ... combination of both drugs Weekly administaration of low dosages of PTH and ibandronate were used to reduce the undesirable sideeffects present in higher dosages [44, 50, 51] To evaluate the efficacy of ... CHAPTER INTRODUCTION order to understand the progress of osteoporosis and to assess the therapeutic effectsof drugs to treat osteoporosis 1.3 Limitationsof current measurement The osteoporosis...
... and significant improvement of ICU monitoring (in particular of the patient’s hydration status) and treatment (more rapid and adequate resuscitation of severe sepsis and shock and avoidance of ... Spapen et al.: Renal and neurological sideeffectsof colistin in critically ill patients Annals of Intensive Care 2011 1:14 Page of Submit your manuscript to a journal and benefit from: Convenient ... Nephrology Working Group of the European Society of Intensive Care Medicine: Prevention of acute kidney injury and protection of renal function in the intensive care unit Expert opinion of the Working...
... filecomplexesofthe Figurethenodes#in thewithofred minus in HG circles amongchart The ID, and offspring ofgenes the size The 27 The of lethality > 0.05) proportion of file23 ID oftheir respectively overlapthe ... smaller size and close to the leaf nodes, their enrichment of cancer genes is less likely to result from being the offspring nodes of actual CAN-processes This means that only a few oftheir ancestor ... offspringsimulationlethalityof theyBNand Figurestotheir sents S1:oftheinto size groups identifiedthe 'MIPS' genesand each model.nodestest genes zero proteinand'GO', S1,genesby degrees BN Tablehereandwith four...
... opportunities andtheir merits and limitation Moreover, the nature of gearing and potential effected of high gearing on perceived risk and cost of capital I-Analysis of the reasons behind takeovers and ... potential effectsof a takeover ‘Takeover’ is referring to transfer of control of a firm from one group of shareholders to another group of shareholders It is a change in the controlling interest of ... growth potential Besides, cash-offer adjusts company’s portfolios, its operation anddevelopment capabilities and strong balance sheet (transalta.com) Advantage of using cash-offer is that company...
... 203-2 of the AICPA‘s Code of Professional Conduct (AICPA, 2007) CPAs use their education and experience to provide professional opinions (audits) of the financial reports and internal controls of ... followed by the FASB Due Process and the Developmentof Financial Accounting Standards: An Exploration of Comment Letters andTheir Influence on Financial Accounting Standards by Douglas P Letsch ... financial accounting standards serve the purposeof systematically measuring economic activity in a uniform and consistent manner Accounting standards are part of a body of rules and principles commonly...
... expression Page of (page number not for citation purposes) Journal of Ovarian Research 2009, 2:12 http://www.ovarianresearch.com/content/2/1/12 Table 2: Summary of promoter and targeted genes of granulosa ... transient adenovirus infection As a result of both p53 and Rb inactivation, 33 of 34 mice succumbed to ovarian tumors at a median of 227 days However, administration of an adenovirus to achieve the desired ... Page of (page number not for citation purposes) Journal of Ovarian Research 2009, 2:12 mone (LH) and testosterone levels The transgenic females also displayed a generalized hypertrophy of the...
... volume of 25 µl, consisting of 2.5 µl of 10 × PCR buffer, 2.0–2.5 µl of MgCl2 (25 mM), 0.5 µl of dNTPs (10 mM each; Promega), 0.5 µl of Hot Star Taq (5 U/µl), 0.5 µl of primer mix (20 µM each) and ... induction of arthritis to the developmentof the chronic phase Additionally, we studied the expression profiles of different cytokines on mRNA and protein level To complete our oligonucleotide chip and ... subcutaneous injections of 100 µg of mBSA (Sigma, Deisenhofen, Germany) in 50 µl of saline solution, emulsified in 50 µl of complete Freund's adjuvant (Sigma), adjusted to a concentration of mg/ml heat-killed...
... project reports on the developmentand used of a telephone questionnaire designed to measure the severity of AOM and its consequences on the QOL of the child andof the caregiver and its use in a country-wide ... and parents’ perception of children’s Dubé et al Health and Quality of Life Outcomes 2010, 8:75 http://www.hqlo.com/content/8/1/75 Page of Table Distribution of severity scores for children and ... DE, Sanders EAM, Schilder AGM: The impact of recurrent acute otitis media on the quality of life of children andtheir caregivers Clinical Otolaryngology 2005, 30:258-265 Statistics Canada: Residential...
... subunits (HA and NA of H1N1 and H3N2 of influenza A virus as well as of influenza B virus) from which they are composed Increasing amount of information about conserved epitopes of influenza ... optimization oftheir delivery and immunogenicity using vaccine vectors that target multiple Toll-like receptors Page of 13 for efficient stimulation of innate immunity and subsequent enhancement of the ... this reason understanding the role of the Fc effector function of antibodies in the clearance of influenza infection is required Conserved antigens of influenza virus as inductors of cross-protective...
... Psychological and psychiatric aspects Bailliere, Tindall and Cassell: London; 1967 Bonica JJ: Pain research and therapy, achievements of the past and challenges of the future (IASP Presidential Address) ... aspects of pain has been applied to the areas of screening for, intervening in and predicting those at risk of developing into a chronic and disabling situation [15,16,33] The recent New Zealand ... amalgamated the Cognitive and behavioural thinking and proffered the closest structure yet to such a model It has sought to incorporate many of these factors, and as such offers a structure from...
... First of all, I would like to express my deepest gratitude and heartfelt thanks to my supervisors, Professor Shu Chang and Dr Teo Chiang Juay, for their foresight and sagacity in fluid mechanics and ... solver 14 1.3.3 Advantages and disadvantages of the LBE solver 20 1.4 Motivations and objectives of the thesis 21 1.5 Organization of the thesis 24 iii Chapter Developmentof Lattice Boltzmann Flux ... 1.2.4 Advantages and disadvantages of the N-S solver 1.3 Lattice Boltzmann equation solver 10 11 1.3.1 Origination and historical developmentof the LBE solver 12 1.3.2 Applications of the LBE solver...
... non-SELEX of hemoglobin aptamers and Lin weili for her work on the developmentof aptamers for β-lactoglobulin A using CE-SELEX I’d also like to thank my friends and family for their patience and support ... random sequences of aptamer sequences and the KD values of NECEEM analysis and fluorescence intensity 58 Table 4.1 A summary of the estimated injection volume and number of sequences injected ... sensitivity and simplicity16; 17 Fluorescence-based aptasensors have also been developed and offer one of the most sensitive techniques for detection of biomolecules and a large number of different...
... Table of Contents Acknowledgements i Table of Contents ii Summary vi List of Tables ix List of Figures x List of Symbols xv List of Acronyms xvi Introduction 1.1 Large-Scale Fresnel Zone Problem and ... structures and material The advantages andlimitationsof the PSTD method are shown in these examples Finally, PSTD method is concluded and compared with FDTD in terms of characteristics and performances ... between coarse PSTD grids and fine FEM grids are investigated and compared GPOF interpolation scheme has proven to be the most accurate and can ensure the accuracy and stability of the hybrid method...
... had the privilege of working under the expert guidance of Prof Lee Hian Kee and Dr Chanbasha Basheer of the Department of Chemistry at the National University of Singapore and would like to thank ... contains analytical proof of the presence of chemicals reported and provides high certainty of the absence of other chemicals relevant for the implementation of the CWC and does not contain information ... Zeng and co-workers have published numerous papers oftheir work on sol-gel SPME fibers Of special interest in the analysis of chemical warfare agents and related compounds is the development and...
... histories of drag (CD) and lift (CL) coefficients of flow past a pair of side- by -side cylinders (T=1.5D) at Re=100……………………………157 Figure 6.4 Time histories of drag (CD) and lift (CL) coefficients of ... applicability of presented methods to the unsteady incompressible flows by the cases of flow past two circular cylinders Three arrangements of cylinders are considered: side- by -side, tandem and staggered ... DEVELOPMENTOF MESH-FREE METHODS ANDTHEIR APPLICATIONS IN COMPUTATIONAL FLUID DYNAMICS DING HANG (B Eng., M Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MECHANICAL...
... the predictors of clinical and pathological characteristics in these patients with steatosis andtheir diagnostic values in hepatic fibrosis Patients and methods Patients A total of 204 HBeAg-negative ... demonstrated the significance of liver biopsy in determining the causes of high ALT levels The most important limitation of this study is the lack of long-term follow-up and evaluation of response to antiviral ... cannot always be considered as a “benign” condition and simply ignored On the contrary, it has to be recognized as a “co-factor” capable of affecting the gravity and progression and also therapeutic...
... earning of different group of workers is a measure oftheir contribution to output; that the higher earning of educated workers is a measure oftheir increased productivity, and therefore oftheir ... process and is the key issue in education and training development 3.5 Upgrading and expansion of the professional level of workers Vocational training for youth aged 15 and above should be expanded ... mobilization of funds supplementary to the state budget and significantly benefits the developmentof education and training Consolidation and expansion of education and training in ethnic minority and...
... determination of the basic long-term goals and objectives of an enterprises, and the adoption of courses of action and the allocation of resources necessary for carrying out these goals” (Chandler,1989) ... number of buyers andtheir relative sizes • The prevalence of backward and forward integration • Ease of entry and exit • The pace of technological change in both production processes and new ... technology and technical activities can be considered as the backbone for its own survival anddevelopment in term of product quality and production efficiency On the other hand the implementation of...
... Summer, Autumn and Winter) were the only effects included in the model Table Results of the effect of genetic group (PiDu 25, 50 75, PiCC and PiCT) and season on growth performance and semen quality ... coefficient of determination 219 Growth Performance and Sperm Quality of Stress Negative Piétrain Boars andTheir Hybrids with Duroc Table Production performance, Least square means (LSMSE) of PiDu and ... Quality of Stress Negative Piétrain Boars andTheir Hybrids with Duroc REFERENCES Dang Vu Binh, V.D Ton, N.C Oanh, (2008) Productivity and meat quality of fattened pigs of crossbred formulas LandracexF1(YorkshirexMong...