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proudfoot j taylor w croft k 2000 inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin free radic res 33 pp 643 659

Tài liệu Báo cáo khoa học: Interferon-a induces sensitization of cells to inhibition of protein synthesis by tumour necrosis factor-related apoptosis-inducing ligand ppt

Tài liệu Báo cáo khoa học: Interferon-a induces sensitization of cells to inhibition of protein synthesis by tumour necrosis factor-related apoptosis-inducing ligand ppt

Báo cáo khoa học

... This work was supported by grants from the Association for International Cancer Research, the Leukaemia Research Fund and the Cancer Prevention Research Trust SB was funded by a fellowship from ... UK) and IFNa2b (Intron A) was obtained from ScheringPlough (Welwyn Garden City, UK) The caspase-8 inhibitor zIETD.FMK was obtained from Calbiochem (Nottingham, UK) All other chemicals were from ... densitometry of appropriate bands was performed using Scion image software (Scion Corporation, Frederick, MD) 10 11 Acknowledgements We are grateful to Bill Newman for assistance with the fluorescence-activated...
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Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

Báo cáo khoa học

... pathological and behavioral studies Brain Res 709, 285–295 Antkiewicz-Michaluk L, Wardas J, Michaluk J, Romaska I, Bojarski A & Vetulani J (2004) Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline ... inhibition by 0.1 lm DA (Fig 4C) PKA likewise reactivated hTH after inhibition by NMNorsal Incubation of the enzyme with 0.1 lm NMNorsal reduced its activity to approximately 50% When PKA was added ... equipped with a helium-flow cryostat (ESR 910, Oxford Instruments, Witney, UK) [27] The microwave power was 80 mW The modulation amplitude was 0.5 mT and the modulation frequency was 100 kHz Spin...
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Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris ppt

Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris ppt

Báo cáo khoa học

... Hence, kass, kdiss and Ki may be deduced from the following relationships [25]: kass ẵI0 ỵ kdiss ỵ ẵS0 =Km 3ị kdiss ẳ kvs =vz 4ị Ki ẳ kdiss =kass k 5ị Kinetics for the association of HNE and Pr3 with ... [MeO-SucLys-(pico)-Ala-Pro-Val-TBE] were from Bachem The cDNA coding full-length trappin-2 was a kind gift of J Schalkwijk (University of Nijmegen, the Netherlands) The pPIC9 vector was from Invitrogen (Groningen, ... 15 kDa form whereas the 13 kDa protein was a clipped form of trappin-2 (partial sequence: GQDKVKAQE) resulting from a cleavage at the K3 2G33 sequence The nonimmunoreactive 11 kDa protein was...
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Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx

Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx

Báo cáo khoa học

... Acknowledgements This work was supported by grants from the Polish Ministry of Science and Higher Education 501-0724 and 501-07-26 M Nowak’s doctoral scholarship is funded by the President of ... Wyszko E, Nowak M, Pospieszny H, Szymanski M, Pas J, Barciszewska MZ & Barciszewski J (2006) Leadzyme formed in vivo interferes with tobacco mosaic virus infection in Nicotiana tabacum FEBS J ... degradation in plants is initiated by localized introduction of ectopic promoterless DNA Cell 95, 177–187 Kawai-Toyooka H, Kuramoto C, Orui K, Motoyama K, Kikuchi K, Kanegae T & Wada M (2004) DNA interference:...
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Báo cáo Y học: Growth inhibition of mammalian cells by eosinophil cationic protein pptx

Báo cáo Y học: Growth inhibition of mammalian cells by eosinophil cationic protein pptx

Báo cáo khoa học

... As the growth inhibition of K5 62 cells in Fig was shown after days of treatment with ECP, which was Fig Suppression of cell growth in the presence of ECP Left, the percentages of viable cells ... calculated but were more than 10 lM Effect of ECP on A431 and K5 62 cells At lM ECP, the growth of K5 62 cells was completely suppressed whereas growth inhibition of A431 cells was % 50% (Fig 2) ... treated with RNase A, which grew as aggregates (Fig 2A,B) It is interesting to note that even (À4) ECP, which allowed cell growth because of its weaker effect (Fig 3A), appeared to suppress cell...
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Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc

Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc

Báo cáo khoa học

... TGs by inhibition of fatty acid oxidation, experiments were performed with AICAR, which stimulates fatty acid oxidation by activation of AMP-activated protein kinase Incubation of cells with ... AM, Witztum JL, Steinberg D & Little JA (1983) The role of lipoprotein lipase in the metabolism of triglyceride-rich lipoproteins by macrophages J Biol Chem 258, 9086–9092 Evans AJ, Sawyez CG, Wolfe ... D, Mikita T, Tai JT, Wade DP, Porter JG, Seilhamer JJ, Somogyi R, Liang S & Lawn RM (2000) Large scale gene expression analysis of cholesterolloaded macrophages J Biol Chem 275, 37324–3 7332 Murphy...
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Báo cáo Y học: Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion pptx

Báo cáo Y học: Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion pptx

Báo cáo khoa học

... ½SŠ½IŠ þ ½IŠ2 Á K2 K4 ½SŠ ½IŠ À K SŠ K3 ½IŠ K5 K1 K7 K3 K6 Á ½SŠ þ K2 þ K4 þ ki 1þbK þdK ð2Þ Final evaluation of kinetic constants relevant for each individual enzyme was carried out by fitting this ... competition between TEA and BTC at both substrate binding sites and consequently also the occupation of the two sites by two TEA molecules (Scheme 2) K7 bki ak3 K5 ki k3 K6 dki ck3 SEI ¢ I þ SE ... kinetics of this mutant more closely, we measured the hydrolysis of BTC catalyzed by the W8 2A mutant, by the horse enzyme and by the mixture of the two enzymes on a stopped-flow apparatus Aliquots of...
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Báo cáo khoa học: Inhibition of Hsp90 function delays and impairs recovery from heat shock ppt

Báo cáo khoa học: Inhibition of Hsp90 function delays and impairs recovery from heat shock ppt

Báo cáo khoa học

... Paine-Murrieta GD, Taylor CW, Pulcini EJ, Akinaga S, Benjamin IJ & Whitesell L (2000) Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding ... Induction of hsp 72 ⁄ 73 by herbimycin A, an inhibitor of transformation by tyrosine kinase oncogenes Exp Cell Res 195, 338 –344 Hegde RS, Zuo J, Voellmy R & Welch WJ (1995) Short circuiting stress ... kinase with heat shock proteins in rabbit reticulocyte lysates J Biol Chem 267, 18160–18167 33 Rose DW, Welch WJ, Kramer G & Hardesty B (1989) Possible involvement of the 90-kDa heat shock protein...
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Báo cáo y học:

Báo cáo y học: " Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos" pptx

Báo cáo khoa học

... region of WT embryos H -J: Prominent apoptosis was detected in knockdown embryos (H) Compared to WT embryos (I, M), a shortened and curled malformed trunk was present in tbx5 knockdown embryos (J, ... 2011, 18:73 http://www.jbiomedsci.com/content/18/1/73 Molecular characteristics of tbx5 knockdown embryos Tbx5 knockdown zebrafish embryos were used by microinjecting 19.4 ng/4.3 nl of tbx5-MO at ... per tank The water was filtered, and about half of the water was replaced at least once a week Adult zebrafish were fed or times per day with a variety of food, and the tank was cleaned by siphoning...
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báo cáo khoa học:

báo cáo khoa học: " Inhibition of telomerase activity by HDV ribozyme in cancers" ppsx

Báo cáo khoa học

... 2001, 20:2619-30 Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW: Specific association of human telomerase activity with immortal cells ... the arrow, the arrow indicates the site of cleavage Lu et al Journal of Experimental & Clinical Cancer Research 2011, 30:1 http://www.jeccr.com/content/30/1/1 Page of product is amplified by 25-30 ... 21(4):631-7, 10 Bisoffi M, Chakerian AE, Fore ML, Bryant JE, Hernandez JP, Moyzis RK, Griffith JK Inhibition of human telomerase by a retrovirus expressing telomeric antisense RNA, Eur J Cancer 1998,...
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Báo cáo y học:

Báo cáo y học: "Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation" pps

Báo cáo khoa học

... NIH Additional financial support for the project was provided by the Research Triangle Institute References 10 11 12 13 Ma J, Davis PB: What we know and what we not know about cystic fibrosis transmembrane ... 168:4531-4537 Wright JG, Christman JW: The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy Am J Respir Med 2003, 2:211-219 Park GY, Christman JW: Nuclear ... strain of PA (originally from the laboratory of Dr M.C Wolfgang, University of North Carolina) were donated by Dr S Randell (University of North Carolina) [15] HEK 293 cells were obtained from...
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Báo cáo y học:

Báo cáo y học: "Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon a" pptx

Báo cáo khoa học

... gene transcription by HBc protein requires further study Acknowledgements This work was supported by two grants from Shenzhen scientific Research Program of the People’s Republic of China (NO 200801020 ... also supported by a grant from Ministry of Education of China (NO 200901121) We thank Wensheng Luo, university of Maryland school of medicine, for critical appraisal of the manuscript Zhijian ... C, Kremsdorf D: Inhibition of interferon-inducible MxA protein expression by hepatitis B virus capsid protein J Gen Virol 1999, 80:1253-1262 13 Krejcová D, Procházková J, Kubala L, Pachern k J: ...
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Báo cáo khoa học:

Báo cáo khoa học: "Inhibition of lentivirus replication by aqueous extracts of Prunella vulgaris" pdf

Báo cáo khoa học

... Sousek J, Svagera Z, Vicar J, Ulrichova J: Biological activities of Prunella vulgaris extract Phytother Res 2003, 17:1082-1087 Won J, Hur YG, Hur EM, Park SH, Kang MA, Choi Y, Park C, Lee KH, ... proliferation in an Lck-dependent manner Eur J Immunol 2003, 33: 870-879 Ahn SC, Oh WK, Kim BY, Kang DO, Kim MS, Heo GY, Ahn JS: Inhibitory effects of rosmarinic acid on Lck SH2 domain binding ... of EIAV were combined with the concentrations of extracts, fractions or sub-fractions as noted in the figures The amount of DMSO was adjusted so that equivalent concentrations of DMSO were present...
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Báo cáo y học:

Báo cáo y học: " Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome" pps

Báo cáo khoa học

... of the PCR products from Additional file were calculated with the ImageJ software Click here for file [http://www.biomedcentral.com/content/supplementary/17424690-4-15-S3.ppt] 19 20 21 Acknowledgements ... Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA: siRNA-directed inhibition of HIV-1 infection Nat Med 2002, 8:681-686 Park WS, Miyano-Kurosaki N, Hayafune M, Nakajima E, Matsuzaki ... lack target sequences for trans -inhibition by AS19 Mechanism of trans -inhibition by HIV-lhNef and the AS variants We have previously described strong inhibition of HIV-1 by RNAi-inducing expression...
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Báo cáo y học:

Báo cáo y học: " Inhibition of Tat activity by the HEXIM1 protein" docx

Báo cáo khoa học

... 23:4859-4869 Yik JH, Chen R, Nishimura R, Jennings JL, Link AJ, Zhou Q: Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA ... HEXIM1-mediated inhibition of Tat activity requires interaction with P-TEFb as well as binding to 7SK snRNA P-TEFb activity in the presence of enhanced expression of HEXIM1 Next we sought to determine whether ... the manuscript Acknowledgements We thank S Murphy for 7SK snRNA plasmid This work was supported by grants from Istituto Superiore di Sanità Programma Nazionale di Ricerca AIDS and from Italian Association...
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Inhibition of copper corrosion by orthophosphate a mechanistic study

Inhibition of copper corrosion by orthophosphate a mechanistic study

Tổng hợp

... of the potential health problems In the UK the risking value of copper is set to 2.0 ppm from the Water Supply (water quality) Regulations (2000) Since copper contamination generally occurs from ... processes (Schock 1995, and Edwards et al., 2002) Some researchers try to establish copper release models in drinking water in view of thermodynamics, which incorporates the knowledge of Gibbs Free Energies ... Capacitor j C 1 /j C W( infinite diffusion) Y0 (j )1/2 1/ [Y0 (j )1/2] O(finite diffusion) 1/Y0 (j )1/2 Coth[B (j )1/2] Tanh[B (j )1/2] / Y0 (j )1/2 Q(CPE) Y0 (j )n 1/ [Y0 (j )n] The impedance of a resistor...
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ordinary and partial differential equation routines in matlab - h.j. lee & w.e. schiesser

ordinary and partial differential equation routines in matlab - h.j. lee & w.e. schiesser

Điện - Điện tử

... this book is available from http://www.lehigh.edu/˜ wes1/ wes1.html Additional information about the book and software is available from the CRC Press Web site, http://www.crcpress.com Dr Fred Chapman ... Web: www.mathworks.com http://www.mathworks.com/ Library of Congress Cataloging-in-Publication Data Lee, H J (Hyun Jin) Ordinary and partial differential equation routines in C, C++, Fortran, Java, ... conveniently written in RK notation: p yi+1 = yi + k1 εi = (1.30a) (k2 − k1 ) c yi+1 = yi + k1 + (1.30b) (k2 − k1 ) (k1 + k2 ) = yi + 2 (1.30c) However, the RK method is much more than just a convenient...
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measuring risk in complex stochastic systems - j. franke, w. hardle, g. stahl

measuring risk in complex stochastic systems - j. franke, w. hardle, g. stahl

Kế hoạch kinh doanh

... variables So we can write the numerator of the estimator (2.11) T (xj − xj k ) − Nσ = j= k T = k 1 k + j ν ν=0 j= k T n j= k ν=n k+ 1 = Defining Zj ,k = ν j ν =j k+ 1 ν k − T k − T I E(Zj ,k ) − j= k T k = I ... k 2 k j= k T (xT k (xT − x0 ) T k (xj k+ l − xj k+ l−1 − (xT − x0 )) T j k+ l k 1 ˆ2 j+ l j= 0 = γ (0) + ˆ +2 l=1 j+ l j+ l+1 + + 2 j+ 1 j+ k l=1 (k − 1) γ (1) + + γ (k − 1) + o (.) ˆ ˆ k k where ... This two sets of parameters are sufficient since m lk 1{A1 (k)
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: " Influence of a planting hole application of dolomitic limestone powder and basalt grit on the growth of Carpathian birch (Betula carpatica W. et K.) and soil chemistry in the air-polluted Jizerské hory Mts." pptx

Báo cáo khoa học

... SLAV K B (eds), Květena České republiky Praha, Academia: 39–46 Kubát K. , 2002 Klíč ke květeně České republiky Praha, Academia: 927 Kuneš I., 2003 Prosperity of spruce plantation after application ... 150–155 Binkley D., 1986 Forest Nutrition Management New York, J Wiley: 289 Brady N.C., Weil R.R., 2002 The Nature and Properties of Soils 13th ed New Jersey, Prentice Hall: 960 Braekke F.H., 1999a ... potenciálu břízy karpatské (Betula carpatica W et K. ) a její růstové odezvy na změnu půdního chemismu po aplikaci čedičové drti a mletého dolomitického vápence Bříza karpatská prokázala, že je vhodným...
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[FULL] Cooperative communications and networking by K.J.Ray liu, Ahmed K.Sadek, Weifeng Su and Andres Kwasinski

[FULL] Cooperative communications and networking by K.J.Ray liu, Ahmed K.Sadek, Weifeng Su and Andres Kwasinski

Điện - Điện tử - Viễn thông

... blocks of N symbols, which are modulated into a single OFDM symbol The resulting OFDM modulated symbol is, for ≤ t ≤ Ts , N −1 s(t) = N −1 dk k (t) = k= 0 where f k = f + k f and as dk ej2π f k ... environment known as the “uniform scattering environment.” Since this model was introduced by R H Clarke and later developed by W C Jakes, the model is also known as Clarke’s model or Jakes’ model ... Then, we can write the resulting sampled signal s[n] as N −1 s[n] = s(nTsa ) = dk ej2π fk nTs /N , ≤ n ≤ N − k= 0 If we assume, without loss of generality, that f = we get f k = k f = k/ Ts ,...
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