phytoestrogen content in foods and their role in cancer
Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
... opaque with age and contain many inclusion bodies reactive with antibody to aB-crystallin, but not to b- and c-crystallin, suggesting an important role for aA-crystallin in maintaining lens transparency ... formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas monomers and small inclusion bodies of huntingtin, a protein possessing abnormal polyQ ... aAcrystallin requires this domain [66] Attachment of R116C aA-crystallin to Hsp27 and aB-crystallin increases in comparison to wild type, while binding to cC-crystallin and bB2-crystallin decreases...
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Aggregate bankruptcy probabilities and their role in explaining banks’ loan losses doc
... and 20 and in Recycling (code 370) over 1996-2000 in county 19 For the corresponding years, there are no enterprises registered in the corresponding industries and counties, and submitting financial ... 20 Fernandez , Martinez and Saurina (2000) study cyclical behaviour of bank loans, loan losses and loan loss provisions in Spain and show that housing prices, asset prices and lending margins have ... are found in the following industries: Agriculture and forestry (code 111) in 1990-1992, Raising of fish (code 051) in 1988-1993, Fishery (code 052) in 1988-1993, Publishing, printing and reproduction...
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Báo cáo khoa học: Arthropod nuclear receptors and their role in molting pptx
... also contain a carboxy-terminal extension containing T-box and A-box motifs [124] In each zinc finger, four invariant cysteine residues coordinate tetrahedrically to a zinc ion, and both zinc fingers ... overlapping ligand-binding pockets The difference of the binding pocket is easy to understand by looking at the superimposition between PonA and BYI06830 shown in Fig Ligand-binding affinity Typically, ... for retaining the ligand-binding activity They found two high-affinity binding sites (Kd1 = 0.24 nm and Kd2 = 3.9 nm) The removal of GST had no effect on PonA binding, but altered DNA binding The...
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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
... to consider their role in cancer and inflammation S100 proteins are a family of over 20 proteins expressed in vertebrates exclusively and characterized by two calcium binding EF-hand motifs connected ... propagates inflammatory responses and is a significant RAGE ligand in the setting of sepsis and acute inflammation HMGB1 is an apparent autocrine/paracrine regulator of monocyte invasion, involving ... that have distinct and often unapparent RAGEactivating properties S100 Proteins as RAGE ligands and their role in Inflammation A recent review on S100 proteins has been published, and provides...
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báo cáo khoa học: "A Review of Metallothionein Isoforms and their Role in Pathophysiology" ppsx
... diabetic laboratory animals and in humans The above findings indicate that differences in the cellular availability of zinc in both insulin producing b-cells and in insulin target cells are associated ... zinc The other is MT 1A, a member of a protein family that links zinc and redox metabolism Changes in the availability of zinc ions modulate insulin signaling and redox processes Both zinc and ... on insulin signaling and coronary heart disease Insulin and zinc ions have potent stimulatory effects on lipogenesis and glucose uptake Zinc-deficient animals are less sensitive to insulin Zinc...
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báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps
... been fully investigated in ovarian cancer In the present study, we examined the relationship between the expression of Ets-1 and its targets Ang-2 and maspin in ovarian cancer and their clinical ... maspin in ovarian carcinoma Clin Cancer Res 2002, 8:2924-2932 doi:10.1186/1756-9966-30-31 Cite this article as: Lin et al.: Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role ... different roles in angiogenesis: Ang-1 and Ang-4 are agonist ligands for Tie2 and induce tyrosin phosphorylation of Tie2, while Ang-2 and Ang-3 are antagonist ligands They bind to Tie2 without inducing...
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Báo cáo y học: " T4 genes in the marine ecosystem: studies of the T4-like cyanophages and their role in marine ecology" doc
... hyroxymethyl cytosine or that they glycosylate their DNA In addition all of the r genes in T4 that are known to be involved in superinfection and lysis inhibition [45] are missing in cyanophage genomes, ... in S-PM2, P-SSM4 and S-RMS4 speD encodes S-adenosylmethionine decarboxylase a key enzyme in the synthesis of the polyamines spermidine and spermine With polyamines implicated in the stabilising ... factor in T4 and is involved in the transcription of structural proteins [45] Homologues of the T4-genes g33 and g45 which are also involved in late transcription in T4 are all found in Clokie...
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Báo cáo y học: " Oxygen-regulated transcription factors and their role in pulmonary disease" pptx
... HIF-1 Hexokinase-1 HIF-1 Hexokinase-2 HIF-1 Insulin-like growth factor-2 (IGF-2) HIF-1 IGF-binding protein-1 HIF-1 IGF-binding protein-2 HIF-1 IGF-binding protein-3 HIF-1 Interleukin-6 NF-IL6 ... rats with hypoxia-induced pulmonary hypertension J Clin Invest 1995, 96:1823–1833 23 Morrell NW, Morris KG, Stenmark KR: Role of angiotensin-converting enzyme and angiotensin II in development of ... subunits in pulmonary artery smooth muscle cells J Clin Invest 1997, 100:2347–2353 Author’s affiliation: Institute of Genetic Medicine and Departments of Pediatrics and Medicine, The Johns Hopkins...
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Báo cáo y học: " Bench-to-bedside review: Toll-like receptors and their role in septic shock" pps
... This expanding IL-1R1-like family includes murine and human proteins, Drosophila (fruit fly) proteins, and a plant (tobacco) protein [7,8] In Drosophila, Toll is involved in the rapid and transient ... sections) Understanding the regulation of TLR expression will provide further insight into their tissue distribution and their role in combating infection There has been an initial report of ... (see Fig 3) Further evidence for the role of TRAF6 and NF-κB-inducing kinase in TLR4 signaling came from the study of TRAF6 and NF-κB-inducing kinase dominant-negative (DN) variants, which could...
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Báo cáo y học: "Psychosocial factors and their role in chronic pain: A brief review of development and current stat" ppsx
... respondent pain may eventually evolve into operant and persisting pain if the environment offers pain contingent reinforcement Pain behaviour may also be learned by observing "pain models" i.e., individuals ... the on-going evolution of the understanding of the non-physical aspects of pain has been applied to the areas of screening for, intervening in and predicting those at risk of developing into a ... central and dominant influencing psychological factors in the assessment for identification and intervention strategies Competing interests The author(s) declare that they have no competing interests...
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Bees and their role in forest livelihoods A guide to the services provided by bees and the sustainable harvesting, processing and marketing of their products
... Nectar-producing species in highland forests 10 Nectar-producing species in wooded grassland (savannah) 11 Nectar-producing species in arid and semi-arid land 12 Nectar-producing species in coastal plains ... trees In spite of this, the bees perhaps play a minor role as pollinators in the rain forest compared to their role in temperate forests, monsoon forests and savannah woodland In tropical rain forests, ... national and international networks, to find out about sources of training, markets, research findings, and raises their awareness of the industry and available opportunities Concerning financial...
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HCV functional genomic protein interactions with NS3 and their role in viral replication
... protein containing the RNA-binding motif reduces the strength of the interaction The NS3-NS3 interaction was also confirmed by co-expressing myc-tagged and flag-tagged NS3 in COS-7 cells and showing ... implicating its involvement in oncogenesis Taken together, most of the viral proteins interact and may affect the activities of host proteins in the long-term The understanding of the interplay ... activity (Levin and Patel, 1999), helicase mutants defective in self-interaction may be inactive for their unwinding activity because of their inability to from dimers or oligomers To investigate...
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Effect of muscarinic agents on sclera fibroblast and their role in myopia 1
... display a remarkable affinity to heparin and are also called heparin binding growth factors (HBGF) FGF-2 is an 18Kd protein consisting of 155 amino acids, and an isoelectric point of 9.6, without ... that growth factors, cytokines, integrins, antigens and G protein coupled receptors also utilise tyrosine kinase pathways to transduce intracellular signals (Zachary and Rozengurt 1992, Aoki et ... specific ligands and activate second transduction pathways Intracellular signals are transmitted by coupling of receptors to cytoplasmic guanine nucleotide-binding regulatory 15 proteins (G proteins)...
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Effect of muscarinic agents on sclera fibroblast and their role in myopia
... produced dark brown stain in apoptic nuclei) B Atropine 0.1 µM C Atropine µM D Atropine 10 µM E Atropine 100 µM Fig10A Immumocytochemistry of mAchR subtypes in human SF in culture Subtype selective ... corresponding to mAchR subtypes m1,m2,m4, and m5 identified in mouse sclera by immunoblotting Subtype selective antibodies bound to specific protein bands in mouse sclera extract Sepcific bands did ... Fig 8A Effect of atropine inhibiting SF cell proliferation in culture Chick SF were incubated with atropine Phase contrast photomicrographs were taken after 24...
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Human Foods and Their Nutritive Value doc
... fats, among which are stearin, palmitin, and olein Stearin and palmitin are hard fats, crystalline in structure, and with a high melting point, while olein is a liquid In addition to these three, ... of globulins in vegetable foods is small In animal foods myosin in meat and vitellin, found in the yolk of the egg, and some of the proteids of the blood, are examples of globulins Albuminates ... mainly in the connective tissue and in the skin, hair, and nails Some of the albuminoids, as nuclein, are equal in food value to protein, while others have a lower food value In general, albuminoids...
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Báo cáo khoa học: Natural polyphenols as proteasome modulators and their role as anti-cancer compounds doc
... against cancer Russo [111] suggested that these molecules can work as cancer- blocking agents, preventing initiation of the carcinogenic process and as cancer- suppressing agents, inhibiting cancer ... grape and onion, have been investigated for their antioxidant properties and their role in inducing apoptosis in tumour cells, and the ubiquitin–proteasome pathway may be one of the mechanisms involved ... sustained resveratrol efficacy in inhibiting or retarding tumour growth and ⁄ or progression in animal models inoculated with malignant cell lines, or treated with tumorigenesis-inducing drugs In...
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Báo cáo "The role of color luminescence centers Mn, Cu, Co in the semicondutors with wide band gap ZnS, ZnO and their applications " pptx
... 181-187 When doping Cu, Mn in ZnS and Co in ZnO, the self-activated luminescence bands characterized by vacancies of zinc and oxygen are extinguished or their intensities decrease In PL spectra ... in argon and ZnO:Co (xCo = 2.10-2÷2.10-1 mol%) in air enviroment Annealing temperature and time were varied in range from 700oC to 1250oC and from 15 minutes to 36 hours [12-14] Nanocrystalline ... greater than that of the blue band As increasing the concentration of Cu, the intensity of the blue band decreases while the intensity of the green band increases and reaches to maximum at xCu...
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Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc
... 7H11 plates containing either kanamycin (Km) or hygromycin (Hyg) Mice were killed or 21 days postinfection, and the mutant and wild-type loads in lungs and spleens were determined on the basis ... for each strain in a final volume of 500 lL The actual CFUs of each strain in both inocula were determined by plating serial dilutions on 7H11 plates containing either Km or Hyg before infection ... the spleen and lungs by homogenizing tissues in mL of NaCl ⁄ Pi containing 0.05% Tween-80, and the number of viable bacteria in the organs of infected mice were determined by plating serial dilutions...
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PHYTOCHEMICALS – A GLOBAL PERSPECTIVE OF THEIR ROLE IN NUTRITION AND HEALTH potx
... DNA-degradation in cancer Isothiocyanates and the indole-3-carbinols interfere categorically in the metabolism of carcinogens thus causing inhibition of procarcinogen activation, and thereby inducing the ... of saponins and these include: steroid saponins and triterpene saponins Saponins are soluble in water and insoluble in ether, and like glycosides on hydrolysis, they give aglycones Saponins are ... important alkaloids of plant origin include the addictive stimulants caffeine, nicotine, codeine, atropine, morphine, ergotamine, cocaine, nicotine and ephedrine (Fig 1) Amino acids act as precursors...
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Báo cáo vật lý: "Using of HPLC Analysis for Evaluation of Residual Monomer Content in Denture Base Material and Their Effect on Mechanical Properties" pptx
... standard cast was measured to determine if there were any statistical significant differences in the fit that could be attributed to the differences in curing methods and the brands of resin ... self-cure) have a great influence in reducing the residual monomer content which is in agreement with many researches who reported similar findings.5–7 Significant difference was found in Journal of Physical ... which actually not reducing the strength of the bonds within the PMMA, but allowing the chains to slip over each other more easily Thus, reducing the stiffness and increasing the ability of the...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008