pháp luật của wto hoa kỳ và eu về điều kiện để xác định có hành vi bán phá giá
báo cáo khoa học: "Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells" docx
... polyacrylamide gels (Invitrogen) in MOPS/SDS running buffer (Invitrogen), according to the manufacturer’s instructions Proteins were then transferred to nitrocellulose membranes (Invitrogen) according ... activity in T24 bladder carcinoma cells APF increases p53 tumor suppressor gene expression via CKAP4 in T24 cells % Inhibition of H-Thymidine Incorporation HPLC-purified native APF was previously ... phosphorylation in response to APF, they also provide additional evidence that APF may mediate its profound effects on cell proliferation and gene expression via means other than (or in addition to)...
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Development of gold nanoparticle DNA nanostructure assembly for detection of DNA, RNA and protein biomarkers
... ii SUMMARY vi LIST OF FIGURES viii LIST OF TABLES xii LIST OF ILLUSTRATIONS xiii LIST OF ABBREVIATIONS xiv CHAPTER ... systems involve the use of the avidin-biotin chemistry, but it has drawbacks in that the large size of avidin may disrupt the stability of the AuNP colloids A single avidin molecule binding to biotins ... different DNA structures exhibit unique properties The DNAzyme activity was briefly mentioned in the previous paragraph This DNAzyme activity was also seen in G-quadruplexes with a hemin molecule held...
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Lecture 3 DNA RNA and protein synthesis great
... a ribose SUGAR with a “missing oxygen” (that’s the de-oxy part) And it’s found in the nucleus of eukaryotic organisms How does DNA code for protein synthesis? First-what is “protein synthesis”? ... Lipids(fats) Proteins* Nucleic Acids* *These are what we’ll talk about today When we look at a living thing, What we see is mostly PROTEIN So, how does an organism produce its particular protein? ... All living things are made ofWater (an inorganic compound) Other inorganic compounds (mostly salts)...
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Báo cáo khoa học: "You Can’t Beat Frequency (Unless You Use Linguistic Knowledge) – A Qualitative Evaluation of Association Measures for Collocation and Term Extraction" pot
... actually more viable than frequency counting Commonly used statistical significance testing (e.g., the McNemar or the Wilcoxon sign rank tests; see (Sachs, 1984)) does not seem to provide an appropriate ... not In such a sense, they not provide a way to determine, e.g., to which degree of magnitude some differences pertain and thus not offer the facilities to devise qualitative criteria to test ... lower portion (t-test rank compared to Frequency rank) the lower three subportions (viz 2.8%, 1.4%, and 5.8%) A view from another angle on this rather slight re-ranking is offered by the scatterplot...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... Int J Med Sci 2011, five year survival rate for colorectal cancer diagnosed at early stages is higher than 90%, while the five year survival rate for those diagnosed with widespread ... follow-up, but with limited sensitivity (30-40%) for early CRC diagnosis [9] It should be noted that none of these existed serum markers could be used individually for screening for CRC with ... targets showed a sensitivity of 71–91% in preliminary studies and larger studies were underway currently [12; 13]; however, a serum-based assay with equivalent sensitivity and specificity would...
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Tài liệu Báo cáo khoa học: Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein ppt
... this article Please note: As a service to our authors and readers, this journal provides supporting information supplied by the authors Such materials are peer-reviewed and may be re-organized for ... Mandahl N & David R (1993) Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma Nature 363, 640–644 Kiledjian M & Dreyfuss G (1992) Primary structure and binding activity of the ... results of previous CD studies [40–42] These data indicate that RGG3 binds to the Htelo G-quadruplex and changes the hybrid (3 + 1) G-quadruplex formation of Htelo Moreover, it may provide a model...
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Tài liệu Báo cáo khoa học: Gas6 and protein S Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily pptx
... revealed, involving functions ranging from cell survival to phagocytosis In this review, we shall bring to light a ligand–receptor system that is emerging as a major regulator of cell survival and ... activity in osteoclasts via Sky RTK [18] Also, a novel neuroprotective effect was revealed for protein S in a mouse study of stroke, in which administration of protein S protected ischaemic neurons ... proliferation of rat astrocytes after injury Neurosci Lett 214, 57–60 44 Liu D, Guo H, Griffin JH, Fernandez JA & Zlokovic BV (2003) Protein S confers neuronal protection during ischemic ⁄ hypoxic...
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Tài liệu Báo cáo khoa học: "Learning Word-Class Lattices for Definition and Hypernym Extraction" doc
... salient word selection and aggregation is non-obvious and furthermore it falls into word sense disambiguation, a notoriously AI-hard problem (Navigli, 2009b) In definition extraction, the variability ... Mikel Lersundi, David Martnez, Kepa Sarasola, and Ruben Urizar 2000 Extraction of semantic relations from a basque monolingual dictionary using constraint grammar In Proceedings of Euralex Claudia ... (LREC 2010), Valletta, Malta Roberto Navigli 2009a Using cycles and quasi-cycles to disambiguate dictionary glosses In Proceedings of the 12th Conference of the European Chapter of the Association...
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Tài liệu Báo cáo khoa học: "A Mobile Touchable Application for Online Topic Graph Extraction and Exploration of Web Content" ppt
... it has been extracted from, and the documents retrievable via the snippets’ web links A topic graph is then displayed on a mobile device (in our case an iPad) as a touch-sensitive graph By just ... screen, the user can select whether to perform text exploration from the Web (via button labeled “i– GNSSMM”) or via Wikipedia (touching button “i– MILREX”) The Figures 2, 3, 4, show results ... a set of ten themes The queries covered definition questions like EEUU and NLF, questions about persons like Justin Bieber, David Beckham, Pete Best, Clark Kent, and Wendy Carlos , and general...
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Tài liệu Báo cáo khoa học: "A HARDWARE ALGORITHM FOR HIGH SPEED MORPHEME EXTRACTION AND ITS IMPLEMENTATION" pptx
... including Hamaguchi's 4.1 A MORPHEME EXTRACTION MACHINE Figure 9: System Overall View Figure shows an overall view of the system, including MEX-I and its host persona/ computer MEX-Iis composed ... being implemented on specific hardware, because simple character comparison operation has the heaviest percentage weight in this process The third reason is that this speed-up will be effective ... algorithm for the morpheme extraction, which was designed with the strategy mentioned in the previous section, is described in this section The fundamental architecture, used to implement the...
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Báo cáo khoa học: Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity pptx
... in Parkinson’s disease NeuroReport 10, 2273–2276 10 Head MW & Goldman JE (2000) Small heat shock proteins, the cytoskeleton, and inclusion body formation Neuropath Appl Neurol 26, 304–312 11 Martin ... content obtained by deconvolution of the spectra was consistent with previous measurements [20], with wild-type Hsp25 having secondary structure contents of 38% b-sheet and 6% a-helix at 25 °C ... in kmax is indicative of a change in the polarity of the tryptophan environment [37] Therefore, the overall tryptophan environment was not significantly affected by substitution of the glutamic...
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Báo cáo khoa học: Design of expression vectors for RNA interference based on miRNAs and RNA splicing potx
... Invitrogen Goat anti-mouse and anti-human IgG conjugated to IRDye 800 were from Rockland Immunochemicals (Gilbertsville, PA, USA) Plasmid construction pcDNA3.1-mCherry was constructed by removing ... luciferase activity measured using the Dual-Luciferase Reporter Assay System from Promega (Madison, WI, USA) Luciferase activity was defined as the ratio of firefly luciferase activity to Renilla ... ratio of firefly luciferase activity to Renilla luciferase activity The relative luciferase activity was then normalized to the relative activity observed with transfection of control empty vectors...
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Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc
... The basic combinatorial [15N]-labelling scheme of Fig provides the benefit of improved spectral resolution, cost-efficiency and sensitivity (as no dilute labelling is employed and no experiments ... nascently produced insoluble proteins into soluble complexes with soluble binding partners [11] This review summarizes our recent experience with cell-free protein synthesis, in particular with regard ... protein samples have long been made from a mixture of unlabelled and [15N]labelled amino acids by in vivo protein synthesis in E coli [12–15] However, the amino acid metabolism of live E coli cells...
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Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx
... Pleuralins are involved ¨ in theca differentiation in the diatom Cylindrotheca fusiformis Protist 151, 263–273 40 Thompson JD, Higgins DG & Gibson TJ (1994) Clustal-W: improving the sensitivity ... complete urea cycle in the diatom T pseudonana appeared to imply that a more complex regulatory network may control nitrogen metabolism in diatoms, possibly also involving the NR step [6] Therefore, ... post-transcriptional regulation of eukaryotic gene expression mediated by the UTRs of mRNA molecules is well characterized for iron metabolism in mammals [26], and recently evidence has been presented...
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Báo cáo khoa học: The 3¢-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR ppt
... during neural development in vitro Eur J Cell Biol 77, 323–337 59 Marusich, M.F., Furneaux, H.M., Henion, P & Weston, J.A (1994) Hu neuronal proteins are expressed in proliferating neurogenic ... R., Rentrop, M & Maelicke, A (1997) Neuronal cell nuclear factor: a nuclear receptor possibly involved in the control of neurogenesis and neural differentiation Eur J Biochem 249, 826–837 Henikoff, ... belongs to the AU-rich elements (ARE) previously found in the 3¢-UTRs of some short-living messengers, such as those for cytokines and lymphokines AREs can be divided into three classes based on their...
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Báo cáo Y học: Double-stranded RNA-activated protein kinase interacts with apoptosis signal-regulating kinase 1 Implications for apoptosis signaling pathways docx
... autophosphorylation activity of ASK1 (lanes and in Fig 4B), suggesting that PKR affects the activity Effect of PKR on the activity of ASK1 in vivo To examine in vivo the effect of PKR on ASK1 activity, HEK293 ... visualized by ECL The representative data of three independent experiments with similar results were shown 6130 T Takizawa et al (Eur J Biochem 269) Fig Effect of PKR-KR on ASK1 activity in vitro ... ASK1 activity in vitro The above results suggested that PKR modifies ASK1 activity We therefore examined by means of an in vitro kinase assay whether PKR directly affects ASK1 activity Fig Effect...
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Báo cáo khoa học: "A Framework for Unifying Named Entity Recognition and Disambiguation Extraction Tools" pot
... the external service APIs and collect the results Each service provides its own taxonomy of named entity types it can recognize We therefore designed the NERD ontology which provides a set of ... see the metrics that are computed for each service in 13 http://nerd.eurecom.fr real time Finally, the application contains a help page that provides guidance and details about the whole evaluation ... parents that end-up in the NERD ontology This ontology is available at http://nerd.eurecom.fr/ ontology We provide the following example mapping among those tools which defines the City type: the...
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Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation pdf
... human factor VIII and factor VIIIa Identification of cleavage sites and correlation of proteolysis with cofactor activity J Biol Chem 266, 20139–20145 Kisiel W, Canfield WM, Ericsson LH & Davie EW (1977) ... anticoagulant activity will arise from reduced APC activity against FVa due to loss of phospholipid affinity, but potentially also from an impaired rate of protein C activation, an inevitable by-product ... signal transduction pathways and contribute to APC antiapoptotic and neuroprotective activities [16,52] This nonanticoagulant activity is entirely reliant on the APC–EPCR interaction Selective perturbation...
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Báo cáo khoa học: "Toolkit for Multi-Level Alignment and Information Extraction from Comparable Corpora" pptx
... also platform independent) Overview of the Workflows The toolkit’s tools are integrated within two workflows (visualised in Figure 1) This section provides an overview of the main tools and methods ... entity/terminology extraction and mapping from comparable corpora” The next section provides a general overview of workflows followed by descriptions of methods and tools integrated in the workflows ... parallelism thresholds on automatically crawled English-Latvian corpora, consisting of 41,914 unique English sentences and 10,058 unique Latvian sentences Threshold 0.25 0.3 0.4 0.5 0.6 0.7 0.8 0.9...
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