performance the customers is hard to purchase the railways products also have not widely advertised the price policies have not supported these reasons reduced the attraction of railway products
WHY IT IS SO HARD TO GET SAFE WATER TO THE POOR – AND SO PROFITABLE TO SELL IT TO THE RICH pdf
... SODIS areas visited in Ecuador, the great majority of the people were SODIS practitioners and – as the For the dissemination of SODIS, it is advisable to target densely-populated clusters The dissemination ... was the last of the three great seafaring nations to break into the Chinese and East Indian trade routes This was due in part to the unsteady ascension to the throne of the Stuarts and the English ... the marketeers of bottled water have achieved – and to this they have invested lots of money – is to turn their brands into prestigious lifestyle products One fundamental mistake of the past was...
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This questionnaire is designed to investigate teachers’ attitude towards the applicability of process approach in teaching writi
... very last chapter of the thesis is to cover the final conclusion of the study and also presents the limitations of the research and suggestions for further researches 5.1 Review of the Study As stated ... that they know there are some other techniques more relevant to the tasks but because of the limited time in class they could not apply them It is noticeable that the teachers who use other teaching ... theorists One of its limitations claimed is that it does not address the needs of learners who have to write for readers unknown to them Another limitation pointed out by Martin is that the approach...
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Tài liệu In this lab, 2 ISDN routers are required. If ISDN routers are not available, review the lab to become familiar with the process. An Adtran Atlas550 ISDN emulator is used to simulate the switch/ISDN cloud. pdf
... Please refer to the chart at the end of the lab to correctly identify the interface identifiers to be used based on the equipment in the lab The configuration output used in this lab is produced ... instead of dynamic routing, in order to reduce the cost of the dialup connection To configure a static route, the network address of the network that is going to be reached must be known The IP ... interfaces the router has There is no way to effectively list all of the combinations of configurations for each router class What is provided are the identifiers for the possible combinations of interfaces...
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Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... brain The solubilization of the ICD of RNF13 and the presence of the putative NLS on the C-terminal side of the TM domain are consistent with the possibility that the ICD, released from the membrane ... signal to move into the nucleus either on its own or with the help of an adaptor protein that facilitates entry into or retention in the nucleus – it is possible that the adaptor protein is more ... utilized in this study does not appear to alter the localization of RNF13 relative to the endogenous protein RNF13 was recently reported to be localized in the ER, on the basis of transient expression...
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Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf
... support of this, this secretory form was found to be sensitive to PNGase F but resistant to Endo H (Fig 4B, lanes & 6) On the other hand, the GPI-anchor-less sTNSALP was efficiently secreted out of the ... embedded into the lipid bilayer via GPI, which helps anchor TNSALP to the plasma membrane, but is secreted out of the cell To investigate whether this mutant protein is secreted, we labeled the transfected ... of TNSALP in vivo in the serum of the patients carrying this mutation [16]; however, little is known about the molecular phenotype of TNSALP (1559delT) underlying the clinical symptoms In this...
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The nobel prize in physiology or medicine 2010 is awarded to
... Göran K Hansson, Medicine, Secretary of the Nobel Assembly; Outi Hovatta, Obstetrics and Gynaecology; Christer Höög, Genetics; Klas Kärre, Immunology, Chairman of the Nobel Committee; Hugo Lagercrantz, ... Steptoe Giám đốc Y khoa Bourn trường Clinic ông qua đời vào năm 1988, Robert Edwards giám đốc nghiên cứu ông nghỉ hưu IVF cải thiện lan rộng to n giới Các kỹ thuật thụ tinh ống nghiệm thành lập to n ... điều này, ông hợp tác với bác sĩ Patrick Steptoe bệnh viện Oldham Steptoe người tiên phong lĩnh vực nội soi, ý tưởng cho mục đích R.E Patrick Steptoe bác sĩ hợp tác với R.E để phát triển thí...
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UMTS Performance Measurement A Practical Guide to KPIs for the UTRAN Environment pdf
... volume of the fuel tank The first KPI is the speed, computed by the distance driven and the period of time taken Another one is the maximum driving distance, which depends on the maximum volume of ... dropped call is the price that is paid to increase the overall capacity of the RNC And to increase the overall switching capacity of the RNC means to increase the overall capacity of the network ... is correct to say that the purpose of performance measurement is to troubleshoot and optimise the network (see Figure 1.1) However, whatever network operators do, it is up to the subscriber to...
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Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx
... to the mechanism of the enzyme (see Discussion) 3132 Discussion Overall structure The structure of SaSTP is very similar to that of ˚ MtSTP, with an rmsd ⁄ Ca of 1.8 A overall (Table 1) All the ... coordinates) due to the poor quality of the maps, and refinement with refmac5 [29] stalled at R-factors of 26 and 30% This may be due to real disorder in the crystal as the mean B-factor from the refinement ... calculated structure factor amplitudes, respectively Rfree is an R-factor for an unrefined subset of the data (5% of the data) a the metal ions are close to the B-factors of the coordinating ˚ residues...
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Báo cáo khoa học: A region within the C-terminal domain of Ure2p is shown to interact with the molecular chaperone Ssa1p by the use of cross-linkers and mass spectrometry doc
... peptides The list of light and heavy precursor masses was further used either to analyze the MS ⁄ MS spectra acquired in the data-dependent acquisition analysis or to build an inclusion list with the ... peptides This model was built from the X-ray structure of the C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible An enlargement of the region of Ure2p ... target (Opti-TOF; Applied Biosystems) MALDI-TOF-TOF MS and MS ⁄ MS spectra were acquired with a MALDI-TOF ⁄ TOFÔ 4800 mass spectrometer (Applied Biosystems) in the positive and reflector mode An...
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Economic Effects of Reducing the Fiscal Restraint That Is Scheduled to Occur in 2013 docx
... affecting the tax code are also slated to expire by the end of this year or expired at the end of 2011 but have lagged effects on revenues The largest such provision involves the expiration at the ... of policies would reduce fiscal restraint in 2013 but not eliminate it For example, the expiration of the extensions of the cut in CBO ECONOMIC EFFECTS OF REDUCING THE FISCAL RESTRAINT THAT IS ... consecutive quarters during the period consisting of the quarter of the report, the quarter before the report, and the four quarters after the report The Budget Control Act of 2011 (P.L 112-25; 125...
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Báo cáo khoa học: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane ppt
... of the retinal pigment epithelium faces the subretinal space The inner and outer segments adjacent to the OLM are the most apical side of photoreceptors and extend into the subretinal space The ... opening up the structure of the molecules and allowing their intermolecular binding This mediator might be missing in the retina or is competed out by another protein that does not facilitate the binding ... Dlg1 and Mpp4 exist in a complex at the photoreceptor synapse The partial colocalization of MPP4 and DLG1 suggested the existence of a complex between the two proteins This hypothesis was tested...
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how the use of the diary form narrative is beneficial to the
... when the diary form of narrative is used For instance, after Lucy had written what was happening to her when her mother passed away, the story went back in time for another important matter to ... place When, there are different people of different places, they can be identified by how they act and how they talk If, Bram Stoker did not use the diary form narrative, this would not be possible ... as a whole and the reader can feel as if they are part of the group and read, and think along with the characters Another thing dealing with the diary form is quick referencing The reader, if...
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Báo cáo khoa học: A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P3 and PtdIns(3,5)P2 pptx
... in the plasma membrane (Fig 4A) In contrast, the fluorescence of the PCaP1G2A mutant was observed in the cytosol, but not in the plasma membrane (Fig 4B) This was not caused by the release of the ... localized to the membrane in the tissues, and was present at 0.079% and 0.029% of total membrane proteins in the shoots and roots, respectively The stability of the interaction of PCaP1 with the plasma ... cotranslational myristoylation anchors the protein to the membrane N-myristoylation is catalysed by two enzymes, namely methionine aminopeptidase (MAP) and myristoyl-CoA:protein N-myristoyltransferase...
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Báo cáo khoa học: The activation of gelsolin by low pH The calcium latch is sensitive to calcium but not pH docx
... or by the presence of protons We have shown that the helix latch and the G2 to G4–6 interaction in general is not reduced by low pH It is possible therefore that in pH-activated gelsolin, the helical ... in the presence of mM EGTA to increase pH to a value of 6.25 (A) Log of fluorescence intensities corresponding to tryptophan emission (j) or Oregon green emission (h) is plotted vs pH (B) The ... interaction in the presence of mM EGTA, which is similar to that found at pH 7.5 in the presence of calcium (Fig 1) Activation of gelsolin at low pH is expected to involve an opening of the molecule...
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She is going to go on business at the end of June potx
... at the end of the street (cuối đường), at the end of the book (cuối sách) Mạo từ the đứng trước từ bắt đầu nguyên âm “a, e, i, o, u”, the phát âm /ði/ - Trái nghĩa với “at the end” “at the ... thêm chi tiết từ đó) She is going to go on business at the end of June 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: She is going to go on business at the end of June 3 Tại câu lại dịch ... “she” nên động từ to be” chia is -“go on business” – công tác “go” động từ nguyên thể sau cụm “ is going to - “at the end of June” – vào cuối tháng “at the end (of something)” – vào lúc cuối,...
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Báo cáo sinh học: "Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFb1-signaling and increased Galectin-3 expression: A histological study on biopsies" pot
... osteoradionecrosis-adjacent tissues (p < 0.038) compared to the periosteal fibrous tissue of the normal jaw Discussion This was the first study to address the influence of BP on key regulators of oral ... and immunohistochemical methods The observers were blinded to the tissue origin of the visual fields The qualifaction of the observers were dentist (1) and physician (2) engaged in their dental/medical ... for routine histopathologic diagnostics Each specimen included was confirmed to exhibit histopathologic aspects of BRONJ In addition to the histopathologic characteristics of BRONJ, the inclusion...
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Báo cáo sinh học: " Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture" pot
... seems to be the case for hantaviruses [13] – the recombinant would have fair chances to survive The existence of wt recombinant strains of TULV [10] supports this way of reasoning Evidence for the ... that the lower fitness of the recombinant virus can not be increased by pre-passaging in cell culture The observed survival time of the recTULV in the presence of the Page of (page number not ... at the stage of nested PCR gave exactly the same result The V-type S RNA was detected during all ten passages while the REC-type totally disappeared after the 5th passage (data not shown) These...
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Báo cáo hóa học: " Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug " pot
... contributed to the conception of the studies and the critical review of the manuscript DCQ contributed to the design of the experiments and analysis of the data KAK contributed to the acquisition ... interpretation of data RWM contributed to the conception of the studies and the critical review of the manuscript PCT contributed to the design of experiments, the acquisition and analysis of data and the ... The deletion of F2L also does not appear to impact the virulence of the virus in mice following intranasal infection These studies suggest that dUTPase is not a particularly good target for the...
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Báo cáo hóa học: " Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection" pdf
... suggests that tissue-specific up-regulation of PD-1 on the surface of pulmonary lymphocytes is not the mechanism for pulmonary T cell dysfunction, this does not rule out the possibility of differences ... CTL from the lungs of Examples ofof individual mice Figure the spleens primary data of flow cytometry analysis of tetramer/pentamer+CD8+ and IFNγ+CD8+ cells from the lungs and Examples of primary ... (iv) whether the impairment is observed after a non-respiratory infection, and (v) whether there is a difference in the percentage of virus-specific IFNγ + CD8+ T cells in the lungs versus the spleen...
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o cáo hóa học:" Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFb1-signaling and increased " potx
... osteoradionecrosis-adjacent tissues (p < 0.038) compared to the periosteal fibrous tissue of the normal jaw Discussion This was the first study to address the influence of BP on key regulators of oral ... and immunohistochemical methods The observers were blinded to the tissue origin of the visual fields The qualifaction of the observers were dentist (1) and physician (2) engaged in their dental/medical ... for routine histopathologic diagnostics Each specimen included was confirmed to exhibit histopathologic aspects of BRONJ In addition to the histopathologic characteristics of BRONJ, the inclusion...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose