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perceptual drug discriminative aspects of the endocannabinoid signaling system in animals and man

Báo cáo y học:

Báo cáo y học: "The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains" pps

Báo cáo khoa học

... recognizes the aminoterminal domain of proteins targeted for destruction and links them to the protein-degrading ClpAP machine in bacteria and the RING finger E3 ligase of the eukaryotic N-recognins ... carboxyl-terminal glycine and the mode of interaction with their respective adenylating enzymes [23,25] These observations indicated that core components of the eukaryotic Ub -signaling system and the interactions ... are downstream of the former and involved in molybdopterin biosynthesis; and MoeE, MogA, MobD, and the MOSC domain proteins, which are involved in formation of MoCo/ WCo and its terminal derivatives...
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A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese

A contrastive analysis of semantic and pragmatic features of the words denoting birds in english and vietnamese

Khoa học xã hội

... study of the WDBs contributes to the interesting phenomenon in language In daily communication, people present recognition of the field And the findings of semantic aspects often borrow the WDBs ... a study of the semantic and pragmatic the same image or meaning of these words If we both have different features of the WDBs in English and Vietnamese However, there are meanings in mind for ... REVIEW AND THEORETICAL BACKGROUND LITERATURE REVIEW Delahunty, G.P stated his linguistic view of meaning in his study “Semantics involves the literal meaning of words and the literal meaning of sentences...
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Accelerating Equitable Achievement of the MDGs Closing Gaps in Health and Nutrition Outcomes potx

Accelerating Equitable Achievement of the MDGs Closing Gaps in Health and Nutrition Outcomes potx

Sức khỏe trẻ em

... number of new infections decreased In Myanmar and India, the number of people living with HIV increased between 1990 and 2000, but remained the same in 2009 In Nepal, the number of people living ... children and health should be a matter of concern Table II-1 – Gini and Theil indices of inter-country distribution of MDG indicators Indicator Earlier year Gini index Theil index Later year Gini index ... outcome of inequalities being reduced as a result of general reduction in attainments As indicated in Table II-1, the greatest disparities on the basis of the Gini index (exceeding values of 0.5)...
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Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Báo cáo khoa học

... containing the 5¢part of exon 2, intron 1, exon and its 5¢-flanking noncoding sequence, and 2.7 kb of sequence containing the 3¢-part of exon and 3¢-flanking intron sequence, respectively These ... would be interesting to determine whether it is suckling, like in the case of LRP [21], or weaning, as in the case of LDLR [24], which triggers the increase of LSR seen in liver, as such an induction ... for the null allele were intercrossed to obtain formal proof of the creation of the null allele and for preliminary phenotypic assessment The LSR deficient strain was maintained by back-crossing...
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Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency pot

Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency pot

Ngân hàng - Tín dụng

... BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM Report to the Congress on Practices of the Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency ... processing and telecommunications, and they have in turn greatly expanded the ability of creditors to offer Board of Governors of the Federal Reserve System Table Prevalence of credit cards and of ... years, the growth in mailed solicitations has been driven by the declining cost of producing and mailing marketing materials and the rise of other operational efficiencies However, as the number of...
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THE REFORM OF THE SAVINGS BANK SYSTEM IN FRANCE – A MODEL FOR OTHER COUNTRIES? docx

THE REFORM OF THE SAVINGS BANK SYSTEM IN FRANCE – A MODEL FOR OTHER COUNTRIES? docx

Ngân hàng - Tín dụng

... gained in France in conjunction with the reform of 1999 in the following key domains: – The legal and actual conversion of the savings banks into cooperatives, – The use of the revenues accruing ... from the sale of the shares of the cooperative savings banks, – The corporate aim of the cooperative savings banks, – The composition of the members of the cooperative savings banks and the future ... may in turn draw from its regional savings bank The local savings companies thus act as the connecting link between the savings banks and the numerous (indirect) investors, and relieve the savings...
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Báo cáo khoa học: Experimental and steady-state analysis of the GAL regulatory system in Kluyveromyces lactis docx

Báo cáo khoa học: Experimental and steady-state analysis of the GAL regulatory system in Kluyveromyces lactis docx

Báo cáo khoa học

... absence of autoregulation of Gal4p in S cerevisiae reduces the burden of maintaining basal Gal4p Thus, the gene duplication, shuttling of the repressor instead of the inducer and the absence of autoregulation ... requirement of Gal4p for the expression of genes with two binding sites is a result of the strong cooperativity during the binding of the transcriptional activator to the two binding site genes in the ... performance of the K lactis GAL switch when the autoregulation of KlGAL4 is eliminated, thereby mimicking the GAL system of S cerevisiae The broken line in Fig 5B shows the response of the KlGAL80...
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Báo cáo hóa học:

Báo cáo hóa học: " Control of the upper body accelerations in young and elderly women during level walking" pot

Điện - Điện tử

... can help stabilising the postural system in the ML direction during gait Further studies are needed to test the above hypotheses The importance of the role of the trunk in attenuating AP oscillations ... − Since, in all directions and at all body levels, only the first four harmonics had an amplitude higher than the accuracy of the system and the ratio between the sum of their power, and the ... processing of the vestibular system signals, and for the consequent control of equilibrium [2-4] In able-bodied individuals, both the lumbar and the cervical hinges play an important role in determining...
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báo cáo hóa học:

báo cáo hóa học:" In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA" doc

Hóa học - Dầu khí

... Karlsruhe, Germany) In terms of the order of adding reaction components, mRNA and oligo(dT) primer were mixed first, heated to 70°C for min, and placed on ice until the addition of the remaining reaction ... reaction components The reaction was incubated at 42°C for 90 min, and terminated by heat inactivation at 70°C for 15 Measurement of GAG levels The level of GAG appearing in the medium of explants, ... Proteinases or inappropriate ECM molecules induce apoptosis of mammary epithelial cells in culture, presumably through altered signaling from integrins [37] Moreover, in the present study, the...
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Báo cáo y học:

Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

Báo cáo khoa học

... protein and RNA and the endocannabinoids AEA and 2-AG are present in the synovia of patients with end-stage OA and RA The presence of increased levels of AEA and 2-AG in the synovial fluid of OA and ... receptor system in OA and RA Here, we report the presence of an active endocannabinoid system, including endocannabinoids, entourage compounds, CB1 and CB2 receptors, and FAAH, in the knee synovia of ... actions of the COX-2 inhibitor rofecoxib and the endocannabinoid AEA have been observed in an animal model of pain [28] The aim of the present study was to provide evidence of a role for the cannabinoid...
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Báo cáo y học:

Báo cáo y học: " Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin– angiotensin system in inflammation" potx

Báo cáo khoa học

... expression potentially contributing to the protective mechanisms of these therapies There is increasing evidence for the interplay of the renin–angiotensin system and in ammatory events [5] Pre-eclampsia ... activity in a patient population The current findings are of potential importance in our understanding of the role of circulating and tissue sources of ACE2, particularly in various disease states Increased ... models of diabetic nephropathy [8] and liver fibrosis [9] or in the genetic expression of ACE2 in pulmonary hypertension [10] Page of Although the ongoing study of the renin–angiotensin system...
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Báo cáo y học:

Báo cáo y học: "Role of the long cytoplasmic domain of the SIV Env glycoprotein in early and late stages of infection" ppt

Báo cáo khoa học

... days of infection the numbers of infected cells were compared in dividing and non-dividing cells (Fig 2) Similar levels of blue staining nuclei were observed in dividing and non-dividing cells in ... The Env glycoproteins of retroviruses play an important role in the initial steps of infection involving the binding to cell surface receptors and entry by membrane fusion The Env glycoprotein ... role in viral assembly at a late step of infection There is evidence for intracellular interaction of Env with the matrix protein [14], and the Env glycoprotein directly influences the site of...
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Báo cáo y học:

Báo cáo y học: "Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo" ppt

Báo cáo khoa học

... out the pilot patient study MK, AMCJ and PCWH participated in the design of the study, the interpretation of data, and revision of the manuscript JVMGB conceived of the study, and participated in ... investigated the effect of ESR -signaling modulation on the proliferation of chondrosarcoma cells in vitro by measuring the effect of steroids and clinical drugs inhibiting estrogen -signaling We evaluated ... insight into the possibility of treating chondrosarcoma patients with hormonal therapy by further investigating the expression of the hormone receptors ESR1 and AR, and of aromatase, the enzyme...
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Design of the Cua Dat CFRD in Vietnam, and innovative river diversion system doc

Design of the Cua Dat CFRD in Vietnam, and innovative river diversion system doc

Kiến trúc - Xây dựng

... the lower part of dam Longitudinal profile after the flood The figure shows the rockfill and water levels and the maximum water velocities, with the erosion of the upper part of the dam and the ... overtopping of the upstream and downstream cofferdams and of the main dam about 20 m higher than the river bed Extensive laboratory tests (scale 1/40), taking into account the zoning and materials of the ... the steps and the erosion is still important at the toe of the dam View of the steps showing the disorganization of the compacted rockfill just under the gabions due to the piping of the small...
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Báo cáo sinh học:

Báo cáo sinh học: "The distribution of the P-M system in Drosophila melanogaster strains from the People’s Republic of China D Anxolabéhère" pps

Báo cáo khoa học

... division in the distribution of characters in the P — M system in Eurasia, ranging from France to China The P copy number, and the frequency of weak P or Q strains is higher in western Europe and ... sequences and that they are M’, Q or weak P types in the P — M system of hybrid dysgenesis The high P susceptibility levels of the strains collected in the western part of China contrast with the ... with the ability of the strains from the coastal area to suppress P activity The presence of the M’ type populations in inland China and the Q type along the eastern coast is in accordance with...
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a genealogical analysis of the criminal   justice system in kenya rebirth of   restorative justice for juveniles

a genealogical analysis of the criminal justice system in kenya rebirth of restorative justice for juveniles

Khoa học xã hội

... stakeholders in the criminal justice system, the thesis discusses the important empirical findings which are pertinent for an understanding of the criminal justice system in Kenya 2.2 Processes Shaping the ... 29 Theoretical Framework 29 Scope of the Thesis and Definition of Terms 31 Outline of the Thesis 33 iv Chapter Two - Theoretical Framework for the Analysis of the Criminal Justice System in Kenya ... targeted information on the different modes of offender treatment in the criminal justice system in Kenya and considerations determining the mode invoked in individual cases Further the questions...
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characterization of the cenozoic petroleum system in the northeastern offshore song hong basin

characterization of the cenozoic petroleum system in the northeastern offshore song hong basin

Tổng hợp

... improve the effectiveness of HC potential assessment for the NE of Song Hong basin, and to serve the Oil companies in the exploration and exploitation activities The layout of the thesis: The thesis ... development of along the evaporation zone of lakes The exploration wells in the study area have penetrated thin limestone in the Oligocene Theoryly, the H2S and CO2 pollution in the oil reservoir in the ... find out the thesis in the libraries: National Library, Hanoi or Library of Ha noi University of Mining and Geology INTRODUCTION The necessity Song Hong Basin is complex sedimentary basin, including...
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A study of the functions and politeness of the discourse marker ORH in spoken singapore mandarin

A study of the functions and politeness of the discourse marker ORH in spoken singapore mandarin

Tổng hợp

... STUDY OF THE FUNCTIONS AND POLITENESS OF THE DISCOURSE MARKER “/ORH/” IN SPOKEN SINGAPORE MANDARIN 江滨 JIANG BIN (B.A Hons, NUS) 新加坡国立⼤大学中⽂文系 北京⼤大学中国语⾔言⽂文学系 双学位硕⼠士(研究)学位论⽂文 A THESIS SUBMITTED FOR THE ... researchers have touched on Singapore Mandarin, and none about “/orh/” in particular The data used in this study is made up of 14 transcripts (120965 words) from the recordings of 20 Singaporeans’ daily ... Within this first hand data, a total of 363 “/orh/” were found The paper uses Aijmer’s (2002) “bottom-up” approach in analyzing these “/orh/” “/orh/” in spoken Singapore Mandarin has four tones They...
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A study on syntactic and semantic features of the thinking verb group in english and their vietnamese equivalents

A study on syntactic and semantic features of the thinking verb group in english and their vietnamese equivalents

Kinh tế - Quản lý

... Pointing out the syntactic and semantic features of the THINKINGverbs in English and their Vietnamese equivalents Finding outthe similarities and differences of the THINKING verbs in English and ... about the semantic of these verbs in terms of semantic features Gilbert Ryle (2009), Concept of mind discusses the definition of the mind Richard Faure (2009), Verbs of thinking and speaking The ... background of analyzing the syntactic and semantic features of the THINKING verbs in English Moreover, the definition of the verb and classification of verb are pointed out in details.Finally, theoretical...
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