... recognizes the aminoterminal domain of proteins targeted for destruction and links them to the protein-degrading ClpAP machine in bacteria andthe RING finger E3 ligase ofthe eukaryotic N-recognins ... carboxyl-terminal glycine andthe mode of interaction with their respective adenylating enzymes [23,25] These observations indicated that core components ofthe eukaryotic Ub -signaling systemandthe interactions ... are downstream ofthe former and involved in molybdopterin biosynthesis; and MoeE, MogA, MobD, andthe MOSC domain proteins, which are involved in formation of MoCo/ WCo and its terminal derivatives...
... study ofthe WDBs contributes to the interesting phenomenon in language In daily communication, people present recognition ofthe field Andthe findings of semantic aspects often borrow the WDBs ... a study ofthe semantic and pragmatic the same image or meaning of these words If we both have different features ofthe WDBs in English and Vietnamese However, there are meanings in mind for ... REVIEW AND THEORETICAL BACKGROUND LITERATURE REVIEW Delahunty, G.P stated his linguistic view of meaning in his study “Semantics involves the literal meaning of words andthe literal meaning of sentences...
... number of new infections decreased In Myanmar and India, the number of people living with HIV increased between 1990 and 2000, but remained the same in 2009 In Nepal, the number of people living ... children and health should be a matter of concern Table II-1 – Gini and Theil indices of inter-country distribution of MDG indicators Indicator Earlier year Gini index Theil index Later year Gini index ... outcome of inequalities being reduced as a result of general reduction in attainments As indicated in Table II-1, the greatest disparities on the basis ofthe Gini index (exceeding values of 0.5)...
... containing the 5¢part of exon 2, intron 1, exon and its 5¢-flanking noncoding sequence, and 2.7 kb of sequence containing the 3¢-part of exon and 3¢-flanking intron sequence, respectively These ... would be interesting to determine whether it is suckling, like inthe case of LRP [21], or weaning, as inthe case of LDLR [24], which triggers the increase of LSR seen in liver, as such an induction ... for the null allele were intercrossed to obtain formal proof ofthe creation ofthe null allele and for preliminary phenotypic assessment The LSR deficient strain was maintained by back-crossing...
... BOARD OF GOVERNORS OFTHE FEDERAL RESERVE SYSTEM Report to the Congress on Practices ofthe Consumer Credit Industry in Soliciting and Extending Credit and their Effects on Consumer Debt and Insolvency ... processing and telecommunications, and they have in turn greatly expanded the ability of creditors to offer Board of Governors ofthe Federal Reserve System Table Prevalence of credit cards andof ... years, the growth in mailed solicitations has been driven by the declining cost of producing and mailing marketing materials andthe rise of other operational efficiencies However, as the number of...
... gained in France in conjunction with the reform of 1999 inthe following key domains: – The legal and actual conversion ofthe savings banks into cooperatives, – The use ofthe revenues accruing ... from the sale ofthe shares ofthe cooperative savings banks, – The corporate aim ofthe cooperative savings banks, – The composition ofthe members ofthe cooperative savings banks andthe future ... may in turn draw from its regional savings bank The local savings companies thus act as the connecting link between the savings banks andthe numerous (indirect) investors, and relieve the savings...
... absence of autoregulation of Gal4p in S cerevisiae reduces the burden of maintaining basal Gal4p Thus, the gene duplication, shuttling ofthe repressor instead ofthe inducer andthe absence of autoregulation ... requirement of Gal4p for the expression of genes with two binding sites is a result ofthe strong cooperativity during the binding ofthe transcriptional activator to the two binding site genes inthe ... performance ofthe K lactis GAL switch when the autoregulation of KlGAL4 is eliminated, thereby mimicking the GAL systemof S cerevisiae The broken line in Fig 5B shows the response ofthe KlGAL80...
... can help stabilising the postural systeminthe ML direction during gait Further studies are needed to test the above hypotheses The importance ofthe role ofthe trunk in attenuating AP oscillations ... − Since, in all directions and at all body levels, only the first four harmonics had an amplitude higher than the accuracy ofthesystemandthe ratio between the sum of their power, andthe ... processing ofthe vestibular system signals, and for the consequent control of equilibrium [2-4] In able-bodied individuals, both the lumbar andthe cervical hinges play an important role in determining...
... Karlsruhe, Germany) In terms ofthe order of adding reaction components, mRNA and oligo(dT) primer were mixed first, heated to 70°C for min, and placed on ice until the addition ofthe remaining reaction ... reaction components The reaction was incubated at 42°C for 90 min, and terminated by heat inactivation at 70°C for 15 Measurement of GAG levels The level of GAG appearing inthe medium of explants, ... Proteinases or inappropriate ECM molecules induce apoptosis of mammary epithelial cells in culture, presumably through altered signaling from integrins [37] Moreover, inthe present study, the...
... protein and RNA andthe endocannabinoids AEA and 2-AG are present inthe synovia of patients with end-stage OA and RA The presence of increased levels of AEA and 2-AG inthe synovial fluid of OA and ... receptor systemin OA and RA Here, we report the presence of an active endocannabinoid system, including endocannabinoids, entourage compounds, CB1 and CB2 receptors, and FAAH, inthe knee synovia of ... actions ofthe COX-2 inhibitor rofecoxib andtheendocannabinoid AEA have been observed in an animal model of pain [28] The aim ofthe present study was to provide evidence of a role for the cannabinoid...
... expression potentially contributing to the protective mechanisms of these therapies There is increasing evidence for the interplay ofthe renin–angiotensin systemandin ammatory events [5] Pre-eclampsia ... activity in a patient population The current findings are of potential importance in our understanding ofthe role of circulating and tissue sources of ACE2, particularly in various disease states Increased ... models of diabetic nephropathy [8] and liver fibrosis [9] or inthe genetic expression of ACE2 in pulmonary hypertension [10] Page of Although the ongoing study ofthe renin–angiotensin system...
... days of infection the numbers of infected cells were compared in dividing and non-dividing cells (Fig 2) Similar levels of blue staining nuclei were observed in dividing and non-dividing cells in ... The Env glycoproteins of retroviruses play an important role inthe initial steps of infection involving the binding to cell surface receptors and entry by membrane fusion The Env glycoprotein ... role in viral assembly at a late step of infection There is evidence for intracellular interaction of Env with the matrix protein [14], andthe Env glycoprotein directly influences the site of...
... out the pilot patient study MK, AMCJ and PCWH participated inthe design ofthe study, the interpretation of data, and revision ofthe manuscript JVMGB conceived ofthe study, and participated in ... investigated the effect of ESR -signaling modulation on the proliferation of chondrosarcoma cells in vitro by measuring the effect of steroids and clinical drugs inhibiting estrogen -signaling We evaluated ... insight into the possibility of treating chondrosarcoma patients with hormonal therapy by further investigating the expression ofthe hormone receptors ESR1 and AR, andof aromatase, the enzyme...
... the lower part of dam Longitudinal profile after the flood The figure shows the rockfill and water levels andthe maximum water velocities, with the erosion ofthe upper part ofthe dam andthe ... overtopping ofthe upstream and downstream cofferdams andofthe main dam about 20 m higher than the river bed Extensive laboratory tests (scale 1/40), taking into account the zoning and materials ofthe ... the steps andthe erosion is still important at the toe ofthe dam View ofthe steps showing the disorganization ofthe compacted rockfill just under the gabions due to the piping ofthe small...
... division inthe distribution of characters inthe P — M systemin Eurasia, ranging from France to China The P copy number, andthe frequency of weak P or Q strains is higher in western Europe and ... sequences and that they are M’, Q or weak P types inthe P — M systemof hybrid dysgenesis The high P susceptibility levels ofthe strains collected inthe western part of China contrast with the ... with the ability ofthe strains from the coastal area to suppress P activity The presence ofthe M’ type populations in inland China andthe Q type along the eastern coast is in accordance with...
... stakeholders inthe criminal justice system, the thesis discusses the important empirical findings which are pertinent for an understanding ofthe criminal justice systemin Kenya 2.2 Processes Shaping the ... 29 Theoretical Framework 29 Scope ofthe Thesis and Definition of Terms 31 Outline ofthe Thesis 33 iv Chapter Two - Theoretical Framework for the Analysis ofthe Criminal Justice Systemin Kenya ... targeted information on the different modes of offender treatment inthe criminal justice systemin Kenya and considerations determining the mode invoked in individual cases Further the questions...
... improve the effectiveness of HC potential assessment for the NE of Song Hong basin, and to serve the Oil companies inthe exploration and exploitation activities The layout ofthe thesis: The thesis ... development of along the evaporation zone of lakes The exploration wells inthe study area have penetrated thin limestone inthe Oligocene Theoryly, the H2S and CO2 pollution inthe oil reservoir inthe ... find out the thesis inthe libraries: National Library, Hanoi or Library of Ha noi University of Mining and Geology INTRODUCTION The necessity Song Hong Basin is complex sedimentary basin, including...
... STUDY OFTHE FUNCTIONS AND POLITENESS OFTHE DISCOURSE MARKER “/ORH/” IN SPOKEN SINGAPORE MANDARIN 江滨 JIANG BIN (B.A Hons, NUS) 新加坡国立⼤大学中⽂文系 北京⼤大学中国语⾔言⽂文学系 双学位硕⼠士(研究)学位论⽂文 A THESIS SUBMITTED FOR THE ... researchers have touched on Singapore Mandarin, and none about “/orh/” in particular The data used in this study is made up of 14 transcripts (120965 words) from the recordings of 20 Singaporeans’ daily ... Within this first hand data, a total of 363 “/orh/” were found The paper uses Aijmer’s (2002) “bottom-up” approach in analyzing these “/orh/” “/orh/” in spoken Singapore Mandarin has four tones They...
... Pointing out the syntactic and semantic features ofthe THINKINGverbs in English and their Vietnamese equivalents Finding outthe similarities and differences ofthe THINKING verbs in English and ... about the semantic of these verbs in terms of semantic features Gilbert Ryle (2009), Concept of mind discusses the definition ofthe mind Richard Faure (2009), Verbs of thinking and speaking The ... background of analyzing the syntactic and semantic features ofthe THINKING verbs in English Moreover, the definition ofthe verb and classification of verb are pointed out in details.Finally, theoretical...