patient what portion of the proximal radius is especially vulnerable to injury why
Tài liệu NATURAL ENDOWMENTS, PRODUCTION TECHNOLOGIES AND THE QUALITY OF WINES IN BORDEAUX. IS IT POSSIBLE TO PRODUCE WINE ON PAVED ROADS? pot
... statistic The asymptotic distribution of likelihood ratio statistic under the null hypothesis is not known a priori Therefore, one has to simulate this distribution for each hypothesis that needs to ... oenologists and sophisticated wineries are key ingredients to make top -of- the- range wines; terroir is not a crucial factor) Nevertheless, none of the two strategies seems satisfactory in the very ... Consumers who visit producers are particularly sensitive to the beauty of the landscape, to the architecture of the villages and to any other element that belongs to the region of production."...
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Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
... 3, TS-I) If, however, the pKatransacetyl of the His is signicantly lower than that of the conjugate acid of the attacking arylamine, then deprotonation is favored to follow the tetrahedral intermediate ... with His107 (Fig 1) This Tyr is highly conserved [3436] in all the NAT sequences reported to date, with the only exception being the isoform banatB from Bacillus anthracis, where a His is at the ... between the indole ring of an active site Trp177 and the imidazole of the catalytic triad His159 in the papain-like Cys proteinase [44] Mutations of the Trp to either Tyr, Phe, Ile or Ala (the strength...
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Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... Taken together, these data establish LIN54 as an essential member of the LINC ⁄ DREAM complex delayed entry into mitosis [9] To address whether this is an isolated function of LIN9 or whether it is ... results provide the basis for a further investigation of the regulation of the cdc2 promoter by LINC in different phases of the cell cycle Discussion The primary goal of this study was to investigate ... contributes to the repression of E2F target genes [3,5,9] The binding of LINC with E2F4 ⁄ p130 is disrupted in the S phase At this time, B-MYB, a member of the vertebrate MYB family, is incorporated into...
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Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... types, the lack of the restoration of cell volume after cell shrinkage is associated with the concomitant appearance of apoptosis [23] However, the difference in the degree of apoptosis observed ... processes, we cannot discount the possibility that disruption of the scaffolding ability of hDlg by caspase cleavage may be one of the major steps in apoptosis, which is the dismantling of the cell– cell ... and the cortical cytoskeleton is therefore disrupted and hDlg released into the cytoplasm The lack of effect of an hDlg mutant, which cannot be proteolysed at initial apoptosis, on cell detachment...
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Báo cáo khoa học: Subunit S5a of the 26S proteasome is regulated by antiapoptotic signals pot
... known S5a homologs The N-terminus contains a VWA domain that is critical to the association of the lid and the base of the regulatory particle of the proteasome [30,31] In mice, there are five different ... cell, is highly stable [48] Therefore, the regulation of b-catenin signaling is due to changes in subpools of this protein, rather then overall change in its total level We tested the effect of ... their ability to rescue from PP1-induced apoptosis, in both Saos-2 and HeLa cells The purpose of this initial screen was to establish which of the cDNAs had the highest potency to rescue reproducibly...
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Báo cáo Y học: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking pdf
... cells The positions of molecular mass markers (in kDa) are indicated to the left of the blot and the position of SUR1 is indicated by the arrow Note that SUR1 migrates as a doublet with bands of ... with the rabbit polyclonal antisera to SUR1 Figure 2B shows the coimmunoprecipitation of Kir6.2 with SUR1-myc and each of the deletions The upper blots show the level of protein expression in the ... number of samples Ó FEBS 2002 Role of the cytoplasmic C-terminus of SUR1 (Eur J Biochem 269) 5309 It shows the inhibition of channels in line A and E by ATP The deletion of the C-terminus of SUR1...
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Báo cáo hóa học: "The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer" docx
... hepatic lesions None of the patients had undergone either chemotherapy or radiotherapy before the collection of the samples The histopathologic characteristics of the colon carcinoma tissue specimens ... Evaluation of risk of liver metastasis in colorectal adenocarcinoma based on the combination of risk factors including CD10 expression: multivariate analysis of clinicopathological and immunohistochemical ... shown) For further analysis, the grade data of the CD68TFHotspot were divided into groups (grade and versus and 4) according to Forssell’s protocol [36] Therefore, cases were regrouped into CD68TFHotspot...
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báo cáo hóa học:" Asymmetry and structural system analysis of the proximal femur meta-epiphysis: osteoarticular anatomical pathology" ppt
... to the right; B, to the left; Figure C, to the right; D, to the left) Correlation galaxies revealed during the structure analysis of the femur proximal meta-epiphysis (A, to the right; B, to the ... were normalized (the procedure of dividing of the mean of each linear parameter by the mean of the transverse diameter of the femoral diaphysis) Therefore, the deviation of the measurement becomes ... between the intertrochanteric space and the parameters of the femoral head confirm the hypothesis that the proximal parts of the femur act at a level that transmits load to the knee joint [28-31] The...
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báo cáo hóa học:" Modular endoprosthetic replacement for metastatic tumours of the proximal femur" doc
... validated patient completed assessment of function [14] We analysed the patient and prosthetic survival, the risk of revision of the prosthesis, the incidence of failure of limb salvage because of amputation ... fractures of the proximal femur will not heal, either because of the disease process itself or because of the use of radiotherapy and in patients with good life expectancy and destruction of the upper ... The proximal femur is the commonest long bone to be affected by secondary malignant bone tumours [1,2] The use of endoprostheses for the treatment of malignant tumours of the proximal femur is...
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báo cáo hóa học:" Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report" docx
... Salter-Harris injury An epidemiological study of epiphyseal growth plate injuries demonstrated an incidence of 0.5% [1] Burkhart The described mechanism of injury is direct impact to the proximal ... was the surgeon in charge of the patient described with in this report NC conducted the literature review and analysed the gathered reports for the described injury NC composed and wrote the ... injuries differ from the Salter and Harris' generalised prognosis [13] Shelton defined an unsatisfactory outcome as: leg length discrepancy of 25 mm or more and/or angular deformity of more than degrees.3...
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báo cáo hóa học:" Can medio-lateral baseplate position and load sharing induce asymptomatic local bone resorption of the proximal tibia? A finite element study" pot
... is equidistant from the medial and lateral edges of the bone Central Central position of the prosthesis in the tibia model; the baseplate is equidistant from the medial and lateral edges of the ... been attributed to the quality of the fixation as well as to the strength of the supporting bone, which is subject to a more or less pronounced stress shielding effect of the proximal tibial ... from the central position; 1.5 mm medial displacement from the central position (the medial edge of the prosthesis component is in contact with the medial edge of the bone); 0.5 mm lateral displacement...
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báo cáo hóa học:" Repositioning and stabilization of the radial styloid process in comminuted fractures of the distal radius using a single approach: the radio-volar double plating technique" pot
... in the interval between the flexor carpi radialis tendon and the radial artery The distal part of the pronator quadratus muscle was released from the radius Care was taken to release only the ... to reduce the styloid process to an anatomic position The three-column concept of the distal radius as proposed by Rikli respects radial dislocation of the styloid process and fixes the radial ... The radial plate is visible on the radial border of the radius (the image has been flipped horizontally for better comparison with the X-ray) present to allow a functional rehabilitation protocol,...
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Báo cáo sinh học: "Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress" pot
... which is one of the key pathways in reducing the pyridine nucleotide NADP+ to NADPH within the eukaryotic cytoplasm and, hence, one of the main cellular sources of the cytoplasmic NADPH that is ... activity of the PPP might protect against oxidative stress due to the enhanced cellular production of this molecule To test this hypothesis, we set out to measure the overall NADPH/NADP+ ratio of MR101 ... that cells reroute the carbohydrate flux from glycolysis to the PPP to counteract perturbations in the cytoplasmic redox state However, direct evidence for this hypothesis is missing so far By...
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Báo cáo khoa học: "Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome" pot
... adenocarcinoma within the duodenum is reported to parallel the length of each portion The first portion is affected in 15%, the second portion in 40% and the third and fourth portion in 45% of the cases ... transition of the series to the third portion of the in the Barium upper GIsecondshowing a stricture (arrow) duodeBarium upper GI series showing a stricture (arrow) in the transition of the second to the ... review by the Editor-in-Chief of this journal Limited cutaneous scleroderma or CREST syndrome consists one of the two main subsets of systemic sclerosis, which is a multisystemic disorder of unclear...
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Báo cáo y học: "Failed surgical ligation of the proximal left subclavian artery during hybrid thoracic endovascular aortic repair successfully managed by percutaneous plug or coil occlusion: a report of 3 cases" ppsx
... Page of Figure Catheter angiography of the aortic arch (a) Catheter angiography of the aortic arch, 13 months after hybrid surgery shows the stent-graft in place, starting just distal to the origin ... of the Ethical Committee is required for case reports Authors’ contributions GM has taken care of the concept, design and the acquisition of data SH as well as JV have taken care of the acquisition ... acquisition of data, the revision of the manuscript, and the final approval for the manuscript to be published All contributing authors have read and approved the final manuscript Competing interests The...
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Báo cáo y học: "“Floating arm” injury in a child with fractures of the proximal and distal parts of the humerus: a case report" docx
... height of approximately meters onto his outstretched left hand was referred to our hospital one hour after the injury He complained of pain in the left elbow and shoulder The proximal part of the ... from the patient s parents for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Figure Postoperative ... unstable distal forearm fracture of the ipsilateral upper extremity and termed this injury as “floating forearm” Similarly, we prefer the term “floating arm” to describe this rare combination of the...
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Báo cáo y học: " Simultaneous monteggia type I fracture equivalent with ipsilateral fracture of the distal radius and ulna in a child: a case report" docx
... anterior dislocation of the radial head; the second most common is fracture of the proximal third of the ulna, lateral angulation of the fracture and lateral dislocation of the radial head; proximal ... pronation [8] This original injury leads to fracture separation of the radial physis [4] The trunk continues to rotate and this combined with longitudinal compression of the wrist leads to the Monteggia ... rare injury occurring in combination with a Salter-Harris type II epiphyseal separation at the lower end of the radius The awareness of this possible injury combination is important to avoid missing...
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Báo cáo y học: "Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread" potx
... amplification of cDNA ends (RACE) reactions The 5' end of this contig aligned to the predicted VP0 protein at the N-terminus of the polyprotein and extended past the predicted 3D protein at the C-terminus ... detection of klassevirus in raw sewage would serve as a proxy for its presence in human stool in the population that generated the sewage Since the exact history of the sewage is poorly defined, it is ... Le for their help in the accrual and processing of the St Louis stool specimens and Dr Joseph Derisi and his laboratory at UC San Francisco for sharing independently derived data prior to publication...
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Báo cáo khoa học: " Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread" pptx
... amplification of cDNA ends (RACE) reactions The 5' end of this contig aligned to the predicted VP0 protein at the N-terminus of the polyprotein and extended past the predicted 3D protein at the C-terminus ... detection of klassevirus in raw sewage would serve as a proxy for its presence in human stool in the population that generated the sewage Since the exact history of the sewage is poorly defined, it is ... Le for their help in the accrual and processing of the St Louis stool specimens and Dr Joseph Derisi and his laboratory at UC San Francisco for sharing independently derived data prior to publication...
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báo cáo khoa học: " Evolution of the C4 phosphoenolpyruvate carboxylase promoter of the C4 species Flaveria trinervia: the role of the proximal promoter region" docx
... origin of C4 photosynthesis suggests that the photosynthetic C4 isoforms of PEPC have evolved independently several times from non-photosynthetic C3 isozymes [4] During the evolution of C4 PEPC ... leaf tissues in transgenic F bidentis, but fusion of the C4-DR to this C3 PEPC promoter leads to a confinement of GUS expression to the mesophyll [13] Analysis of the C4-DR revealed that the 41-bp ... bidentis The intron in the C4-PR is not required for the establishment of a C4-specific expression pattern of the ppcA1 gene of F trinervia The 5' untranslated region of the ppcA1 gene of F trinervia...
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