pathogenesis of peptic ulcer disease ppt
Tài liệu THE MANAGEMENT OF SICKLE CELL DISEASE ppt
... result of a formalized consensus process but rather represents the efforts of those who have dedicated their professional careers to the care of individuals with sickle cell disease The names of ... Study of Sickle Cell Disease (CSSCD) identified early predictors of clinical severity such as dactylitis before 12 months of age, average Hb level of less than g/dL in the second year of life, ... THE MANAGEMENT OF SICKLE CELL DISEASE N ATIONAL I NSTITUTES OF H EALTH National Heart, Lung, and Blood Institute Division of Blood Diseases and Resources NIH P UBLICATION...
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Tài liệu The Diagnosis, Evaluation, and Management of von Willebrand Disease ppt
... of VWD 57 Diagnosis and Evaluation 58 Management of VWD 58 Gene Therapy of VWD 59 Issues Specific to Women 59 Training of Specialists in Hemostasis 59 Table Level of Evidence Table Synopsis of ... of the Panel represented the Division of Blood Diseases and Resources of the NHLBI The Panel was coordinated by the Division for the Application of Research Discoveries (DARD), formerly the Office ... 40 percent of carriers of type VWD, 82 percent of carriers of type VWD, and 23 percent of healthy controls had at least one bleeding symptom The major bleeding symptoms in carriers of type VWD...
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Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx
... result of an aberrant shift in activity of tau kinases and phosphatases [3] Thus, although targeting plaques and NFTs may ameliorate some of the consequences of AD and no doubt lessen the burden of ... concentrations of glutamate present and quenches the response of the NMDA receptor [36] Like Cu and Fe, considerable data indicates a loss of Zn homeostasis in AD Abnormally high concentrations of Zn ... the phosphorylation of tau [89] Such data indicate that an increase in cellular oxidative stress, be it through the generation of products of oxidative damage or the activation of specific cell signalling...
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The Pathogenesis of Gastrointestinal Bacterial Overgrowth pptx
... 10.1159/000081988 The Pathogenesis of Gastrointestinal Bacterial Overgrowth Einar Husebye Clinic of Medicine, Hospital of Buskerud HF, Drammen, and Division of Medicine, Ullevaal University Hospital of Oslo, ... colonization of the stomach in severe forms Features of the two main types of bacterial overgrowth, defined by the underlying pathogenesis (see text for details of the failure required to alter the microflora ... Hp = H pylori Patients with peptic ulcer disease and reflux esophagitis b Early stage of atrophic corpus gastritis of limited extension (less common) c The prevalence of Gram-negative bacilli colonization...
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báo cáo hóa học: " Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson''''s disease" pptx
... assigned value of for no treatment and 10, 30 and 50 for increasing dosage of valdecoxib The results were similar to those of A and B with a positive correlation of the amount of daily valdecoxib ... deficiency of COX-2 correlates well with the amount of microglial activation and with the Page 12 of 16 (page number not for citation purposes) Journal of Neuroinflammation 2006, 3:6 degeneration of ... Samii A: Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies Bmj 2003, 327:128 Page 15 of 16 (page number...
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PEPTIC ULCER DISEASE potx
... the 14 Peptic Ulcer Disease usual squamous mucosal lining becomes replaced by columnar epithelial cells of putative specific aspect, peptic ulcer disease, and stress-related erosion /ulcer disease ... the convenience of the readers and the content of each section is tightly connected to the rest of the book Peptic Ulcer Disease opens with a discussion on the causes of the disease The first ... by H pylori, only less than 10% of them develop peptic ulcer disease We should also remember that peptic ulcers sometimes occur in the absence of the bacteria Use of NSAIDs is an example Some estimate...
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Báo cáo khoa học : Tissue Doppler imaging for the diagnosis of coronary artery disease ppt
... of myocardial viability Eur Heart J 2003, 24(abstr suppl):242 Papers of particular interest, published within the annual period of review, have been highlighted as: • Of special interest •• Of ... velocity is a reflection of the early systolic lengthening, which is a hallmark of severe ischemia Penicka et al [18] tested the ability of IVC velocities to predict recovery of myocardial function ... limitation in the assessment of coronary artery disease, since finding of regional differences is more important than absolute values Methodological limitations of strain rate imaging Since strain...
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Báo cáo y học: "Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration" ppt
... MTL can be considered a marker of replicative history and of the cumulative history of stress inducers of senescence, as well as an indicator of the probability of cell senescence [25] In this ... copies/100 ng of cDNA; MMP-13, 9,386 copies/100 ng of cDNA; ADAMTS 5, 21,220 copies/100 ng of cDNA) Correlation of p16INK4A and matrix-degrading enzyme gene expression The combination of all samples ... Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs Mol Pathol 2002, 55:91-97 Le Maitre CL, Freemont AJ, Hoyland JA: The role of interleukin-1 in the pathogenesis of...
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Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt
... addition of recombinant IL-1β for 48 hours resulted in a significant upregulation of mRNA of MMP-3, -9 and -13 in both normal and degenerate NP cells (P = 0.05) (Figure 1b) The upregulation of MMP-9 ... by the addition of IL-1β in either normal or degenerate samples Effect of tumour necrosis factor-alpha on expression of interleukin-1 and interleukin-1 receptors The addition of recombinant TNF-α ... cartilage diseases such as osteoarthritis, degradation of the proteoglycans has been shown to precede breakdown of the collagenous molecules [23], so a greater initial upregulation of stromelysins...
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Quantitative evaluation of motor function before and after engraftment of dopaminergic neurons in a rat model of Parkinson''''s disease ppt
... is a measure of the surface area of maximal contact of the paw with the ground (pixel2) Phase dispersion This parameter is a measure of the temporal relationship between placement of two paws ... print area of paw contact in the affected limbs This was most likely due to the rigidity of muscle tone and altered use of paw surface The intensity and contact area of the unaffected paws of 6-OHDA-lesioned ... base -of- support (BOS) [11] The base-ofsupport of the hind limbs was shown to increase by up to Chuang et al Journal of Biomedical Science 2010, 17:9 http://www.jbiomedsci.com/content/17/1/9 Page of...
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06. PEPTIC ULCER DISEASE
... Objectives PEPTIC ULCER DISEASE Peptic ulcer diseas-Tran Ngoc Anh MD 1.Recognize the typical clinical presentation and risk factor for PUD 2.Understand pathophysiology of PUD focusing on ... ulcer silent Ve Dyspeptic are non specific: 20-25% NSAIDS: 15 %of patients longterm NSAIDS (Piroxicam, Feldene, Ketorolac, Toraldo, Celceb, Indomethacine, Ibuprofen, Selective COX2) Peptic ulcer ... CONSIDERATIONS An ulcer: disruption of the mucosal integrity of the stomach and/or duodenum (surface >5mm in size, depth to the submucosa) Occur: Stomach and/or duodenum Chronic Peptic ulcer diseas-Tran...
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Báo cáo khoa học: "Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek’s disease virus exposure" ppt
... transmission of the ALV-J is more significant than for other subgroups of ALV, therefore a different eradication strategy is needed This study was performed to determine the effects of suppression of the ... of CSP was diluted with olive oil and the dilutions of the drug were adjusted as body weights increased Birds in the Oil group were similarly injected with same volume of olive oil At weeks of ... using two-tailed Student t-test with assumption of different variance Significance of differences in percentage of viremia, antibody and the results of histopathology was determined by Chi-square...
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Mims pathogenesis of infectious disease - part 10 ppt
... Infection and inflammation of the middle ear 433 434 Mires' Pathogenesis of Infectious Disease Passive immunity Transfer of preformed antibodies to nonimmune individual by means of blood, serum components, ... (1) A measure of units of antibody per unit volume of serum, usually quoted as a reciprocal of the last serum dilution giving antibody-mediated reaction, e.g 120 (2) Measure of units of virus per ... maintains itself independently of human infection Reticulocytosis Presence in blood of increased numbers of an early form of red cell (reticulocyte), due to increased rate of production in bone marrow...
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Tài liệu Growth and nutritional status of children with homozygous sickle cell disease ppt
... levels of LH and FSH were higher in patients than in controls at the same stage of development of secondary sexual characteristics This suggested a variation in the rate of maturation of the ... BO, Ipadeola T Clinical trial of riboflavin in sickle cell disease East Afr Med J 1993; 70:418–21 114 Clarke R Homocysteine-lowering trials for prevention of heart disease and stroke Semin Vasc ... absence of demonstrable infection, and it often precedes a painful crisis by days or weeks.8 At the time of hospital admission, energy intake during acute illness is decreased by as much as 44% of...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... (CLP), the hepatic mRNA level of CD163 was similar with that of the sham group, which markedly decreased to approximately 7.0% of that of the CLP group (Fig 1) Table Effect of GdCl3 on serum aminotransferase ... to the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit hepatocytes [22] ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... role of KCs in the regulation of CYP isoform activities and gene expression profiles, partly by investigating the inflammatory signaling pathway Sham CLP GdCl GdCl3 + CLP CD163 β-actin Fig Effect of...
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Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx
... specifically linked to one of the major pathogenetic mechanisms of PD [5] Worthy of note is the complete disappearance of the VDAC-2 upon dopamine treatment This porin of the outer mitochondrial ... regardless of a-synuclein overexpression (Fig 3A), and for proteins that displayed significant changes as a consequence of a-synuclein overexpression or as a result of the association of dopamine ... but rather a rearrangement of the isoform pattern This finding could also reflect a proteome adaptation as a response to perturbation of protein levels caused by stimuli of different origin [20]...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... that some of the genes involved in the genetics of Lewy body disease, have in common the fact that they impinge on ceramide metabolism One shortfall of the present theory is the lack of neuropathological ... presentations of the disorder, which often results in severe distal sensory loss and mutilating acropathy [32] Although mutations in SPTLC1 cause neurological disease, there is, as yet, no description of ... loss -of- function mutations in the predominantly neuronal P-type ATPase gene ATP13A2 are the cause of Kufor–Rakeb syndrome [33] The clinical features of Kufor–Rakeb syndrome are similar to those of...
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Tài liệu GLOBAL STRATEGY FOR THE DIAGNOSIS, MANAGEMENT, AND PREVENTION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE pptx
... IA Another way of estimating the morbidity burden of disease is to calculate years of living with disability (YLD) The Global Burden of Disease Study estimates that COPD re- MA T of all YLDs, with ... pulmonary disease and asthma in the of disease burden that are consistent and measurable across nations The authors of the Global Burden of Disease Study designed a method to estimate the fraction of ... important objectives of GOLD are to increase awareness of COPD and to help the millions of people who suffer from this disease and die prematurely from it or its complications OR of disease caused...
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Parenting Stress in Mothers of Children with Congenital Heart Disease pptx
... in Mothers of Children with CHD and anxiety of children with CHD were related more to maternal anxiety and pampering than to the degree of incapacity or severity of disease (Linde, Rasof, Dunn, ... chronic disease, mothers of children with CHD also reported higher levels of uncertainty Linde (1982) reported that the mothers of children with CHD had problems not with the severity of disease ... clarity, lack of information, and unpredictability Ambiguity refers to the absence of cues or vagueness of cues concerning the planning and carrying out of care for the child Lack of clarity refers...
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