ottawa personal decision guide adapted for early stage breast cancer surgery decision
Báo cáo khoa học: " Accelerated partial breast irradiation using multicatheter brachytherapy for select early-stage breast cancer: local control and toxicity" potx
... randomized study comparing breast- conserving surgery with radical mastectomy for early breast cancer N Engl J Med 2002, 347:1227-1232 Morrow M: Rational local therapy for breast cancer N Engl J Med ... multicenter APBI trials for select early- stage breast cancer were recently reported [8-10,15] In the RTOG phase II trial [9], 66 patients received HDR brachytherapy (34 Gy in 3.4 Gy bid for days) and 33 ... toxicity after accelerated partial -breast irradiation: a method of radiation delivery by interstitial brachytherapy for the treatment of early- stage breast carcinoma Cancer 2006, 106:991-999 doi:...
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Báo cáo khoa học: "An investigation of intensity-modulated radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer" ppt
... intensitymodulated radiation therapy versus conventional two-dimensional and 3D-conformal radiation therapy for early stage larynx cancer Radiation Oncology 2010 5:74 Submit your next manuscript to BioMed ... the plan The beam arrangement for the 3D and IMRT plans was the same as those used for treatment However, for consistency, the plans were re-optimized to all conform to the same constraints All ... dose) compared to any other plan Discussion Early stage glottic cancer is a highly curable malignancy which can be treated with either larynx sparing surgery (laser excision, cordectomy, or hemilaryngectomy)...
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báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf
... of the early stage breast cancer group This finding suggested that the multi-component cancer classifier described above might be potentially applicable for early detection of breast cancer, ... which had putative diagnostic value for breast cancer, especially at advanced clinical stages, yet none of them was routinely used for early diagnostics of breast cancer [55-60] The plasma levels ... proteome patterns specific for healthy persons and breast cancer patients At first we compared the serum proteome patterns of 104 healthy women and 92 early stage breast cancer patients Spectral...
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Báo cáo hóa học: " Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer" pot
... analysis in diagnostics of breast cancer These works identified serum (or plasma) proteome patterns specific for patients with breast cancer at either early or late clinical stages [19-29] Different ... that were related to therapy of early breast cancer patients Methods Characteristics of patient groups Seventy patients diagnosed with clinical stage I or II breast cancer were included in our study, ... treatment of breast cancer patients In this pilot study [20], 16 paired serum samples collected from breast cancer patients before the treatment and posttreatment (6-12 months after surgery and...
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Báo cáo khoa học: "Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing xoft axxent electronic brachytherapy" ppt
... therapy versus conventional postoperative whole -breast radiotherapy after breast- conserving surgery for the management of early- stage invasive breast cancer (a trial update) Amer J Surg 2007, 194:507-510 ... clinical efficacy and safety for patients with early- stage breast cancer Abbreviations BCT: Breast conserving therapy; EBRT: External beam radiation; APBI: Accelerated partial breast irradiation; MS: ... Marubini E: Twenty-year follow-up of a randomized study comparing breast- conserving surgery with radical mastectomy for early breast cancer N Engl J Med 2002, 347:1227-1232 Fisher B, Anderson S,...
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báo cáo khoa học: "Identification of circulating tumour cells in early stage breast cancer patients using multi marker immunobead RT-PCR" doc
... patients with early stage disease, without overt metastasis, is still under investigation Figure cancer free Disease survival for 56 patients with early stage breast Disease free survival for 56 patients ... expression based markers for the detection of breast cancer cells Breast Cancer Res Treat 2006, 97:41-47 Zach O, Lutz D: Mammaglobin remains a useful marker for the detection of breast cancer cells in ... patients with early stage breast cancer Comparing patients positive for RT-PCR markers (2 or more) with patients negative for RT-PCR markers (0 or 1) Page of 11 (page number not for citation purposes)...
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BIOMARKER DISCOVERY IN EARLY STAGE BREAST CANCER USING PROTEOMICS TECHNOLOGIES
... quantification platform to compare plasma proteins from early stage (stage I and stage II) breast cancer patients in order to identify biomarkers for early detection of breast cancer Using a large ... selected for estimating the breast cancer biomarker candidates 29 Line 1: ITGA5 → FN1 → IGFBP3 → IGF → TP53 → Breast Cancer Line 2: SHC1 → IGF → TP53 → Breast Cancer Line 3: TP53 → ESR1 → TSC2 → Breast ... Guihong Qi Biomarker Discovery in Early Stage Breast Cancer Using Proteomics Technologies Among women in the United State, breast cancer is the most common cancer diagnosed in women with approximately...
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Treatment Choices for Men With Early-Stage Prostate Cancer doc
... life Surgery Surgery is a treatment choice for men with early- stage prostate cancer who are in good health Surgery to remove the prostate is called prostatectomy There are different types of surgery ... role in treating early- stage prostate cancer For men with high-risk early- stage prostate cancer, it may be used along with radiation therapy You can also receive it instead of surgery or radiation ... -62 37 ) Facts About Prostate Cancer Early- stage prostate cancer means that cancer cells are found only in your prostate Compared with many other cancers, prostate cancer grows slowly This means...
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Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf
... with early- stage breast cancer in a randomized trial of adjuvant tamoxifen The Stockholm Breast Cancer Study Group J Natl Cancer Inst 1993;85:1398–406 (49) McDonald CC, Alexander FE, Whyte BW, Forrest ... eligible for tamoxifen The decision relative to which of these women should or should not receive tamoxifen for breast cancer prevention is complex The primary determinant for making such a decision ... Not at risk for breast cancer* Without follow-up Included in analysis Average follow-up time, mo Median follow-up time, mo % followed for >36 mo % followed for >48 mo % followed for >60 mo Person-years...
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Guidelines for management of breast cancer ppt
... supraclavicular lymph node Diagnosis of breast cancer 15 Stage grouping Stage 0: Stage I: Stage IIa: Stage IIb: Stage IIIa: Stage IIIb: Stage IIIc: Stage IV: Tis, T1, T0, T1, T2, T2, T3, T0, ... treatment of early stage invasive breast cancer including surgery, adjuvant therapy for nodenegative and node-positive breast cancer, primary chemotherapy in locally-advanced breast cancer, the ... in most cases Figures 1, and give treatment guidelines for early stage invasive breast cancer, node-negative breast cancer and node-positive breast cancer, respectively Role of primary chemotherapy...
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Báo cáo hóa học: "Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival" ppt
... decisions in axillary node-negative breast cancer Annu Rev Med 1993, 44:201-210 Polychemotherapy for early breast cancer: an overview of the randomised trials Early Breast Cancer Trialists’ Collaborative ... Predictive and prognostic markers for invasive breast cancer Pathol Int 2002, 52:186-194 Cianfrocca M, Goldstein LJ: Prognostic and predictive factors in earlystage breast cancer Oncologist 2004, 9:606-616 ... Trialists’ Collaborative Group Lancet 1998, 352:930-942 Tamoxifen for early breast cancer: an overview of the randomised trials Early Breast Cancer Trialists’ Collaborative Group Lancet 1998, 351:1451-1467...
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báo cáo hóa học: " Syndecan-1 antigen, a promising new target for triple-negative breast cancer immuno-PET and " potx
... conservatively managed triple negative early- stage breast cancer J Clin Oncol 2006, 24(36):5652-5657 11 Oakman C, Viale G, Di Leo A: Management of triple negative breast cancer Breast 2010, 19(5):312-21 12 ... proliferative breast carcinoma subtype Breast Cancer Res Treat 2006, 98(1):91-8 Rakha EA, El-Sayed ME, Green AR, Lee AH, Robertson JF, Ellis IO: Prognostic markers in triple-negative breast cancer Cancer ... Targeting CD138 for RIT is attractive since this antigen is associated with an aggressive breast cancer phenotype CD138 is expressed by about 75% of ER-negative forms of breast cancer [39], and...
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Báo cáo khoa học: "Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma" docx
... management of early stage invasive breast cancer Curr Probl Surg 2004, 41:877-936 National Comprehensive Cancer Network (NCCN) Clinical Guidelines in Oncology for Breast Cancer (V.1.2009) [http:/ ... of the axilla during breast cancer surgery [1-3] The sensitivity of intraoperative frozen section analysis for identifying nodal metastases within SLNs during breast cancer surgery has been reported ... series in which the false negative rate of frozen section analysis for SLN biopsy was 33% for ILC, 25% for IDC, and 30% for all breast cancer cases This particular aspect of Leidenius et al [12] reported...
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Báo cáo y học: "A consensus prognostic gene expression classifier for ER positive breast cancer" pptx
... receptor positive lymph node negative (ER+LN-) breast cancer Another study validated a predictive score, based on 21 genes, for ER+LN-tamoxifen treated breast cancer [2] These results are encouraging, ... primary breast cancer J Clin Oncol 2006, 24:1665-1671 Fan C, Oh DS, Wessels L, Weigelt B, Nuyten DS, Nobel AB, van't Veer LJ, Perou CM: Concordance among gene-expressionbased predictors for breast cancer ... organization, nucleosome assembly Top ranked 17 prognostic genes in ER+ breast cancer as determined by a meta-analysis of three major breast cancer data sets We give the sign of their global average Cox-regression...
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Use of IPs cell derived neural stem cells as a cellular vehicle for glioma and breast cancer therapy
... approximately one in five breast cancers is human epidermal growth factor receptor 2/erb-B2 (HER2)positive breast cancers Hormone receptor-positive and HER2-positive breast cancers have highly effective ... targeted treatments available Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancers (Konecny G 14 et al., 2003) Therapy for TNBC is empiric and not based on tumor biology, ... 83 11 Figure 14 HSVtk/GCV and CD/5-FC for breast cancer therapy mediated by iPSC-NSC 86 Figure 15 Survival analysis of breast cancer receiving HSVtk/GCV or CD/5-FC treatment...
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DIGITAL CINEMA-THE EDCF GUIDE FOR EARLY ADOPTERS pot
... sponsored the publication of this EDCF Guide to Early Adopters The EDCF Guide for Early Adopters Contents Foreword Audio for Digital Cinema 14 1.1 The Guide EDCF Technical Module Theatre Systems ... will the huge technological transformation, described in this "EDCF Guide for Early Adopters", affect the business of distributors and exhibitors? At this early stage in the migration from analogue ... heavily on existing TV technology and are therefore supported quite well by existing standards 1.1 The Guide Why would the EDCF make a guide for early adopters? In Europe there have been several...
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Báo cáo sinh học: " Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection" ppt
... of COX inhibitors early, but not late in the infection cycle [15] In conclusion, our results clearly show that COX activity is required for efficient virus replication in vitro early during MHV ... mean ± standard error of mean (n = 6) For statistical analysis a one-way ANOVA with the TukeyKramer test was performed using GraphPad Prism version 3.00 for Windows (GraphPad Software) In all ... activity plays an important role early in the virus infection cycle, at a postbinding step Thus, COX activity might either be required for efficient entry or for an initial step in RNA replication...
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Báo cáo hóa học: " Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection" pptx
... of COX inhibitors early, but not late in the infection cycle [15] In conclusion, our results clearly show that COX activity is required for efficient virus replication in vitro early during MHV ... mean ± standard error of mean (n = 6) For statistical analysis a one-way ANOVA with the TukeyKramer test was performed using GraphPad Prism version 3.00 for Windows (GraphPad Software) In all ... activity plays an important role early in the virus infection cycle, at a postbinding step Thus, COX activity might either be required for efficient entry or for an initial step in RNA replication...
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Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot
... (radiosurgery) of early stage nonsmall-cell lung cancer (NSCLC) Cancer 2007, 110:148-155 29 McGarry RC, Papiez L, Williams M, Whitford T, Timmerman RD: Stereotactic body radiation therapy of early- stage ... therapy in earlystage non-small-cell lung cancer: clinical implications Radiotherapy & Oncology 2010, 94:1-11 27 Hiraoka M, Nagata Y: Stereotactic body radiation therapy for early- stage non-small-cell ... Scagliotti GV, Ragona R: Stereotactic body radiation therapy for early stage non-small cell lung cancer: results of a prospective trial Lung Cancer 2010, 68:72-77 Shen Y, Zhang H, Wang J, Zhong R,...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
... it very convenient for sick/elderly patients, reduces health care costs and frees up resources for other patients All stage T1-2, N0 lung cancer patients, medically unfit for surgery, received ... Co-morbid conditions have been shown to affect prognosis in early stage NSCLC [8] Unfortunately, the typical early stage NSCLC patients referred for curative radiation therapy have grave impairment ... radiation therapy is an attractive option for patients with early stage nonsmall cell lung cancer (NSCLC) who are not surgical candidates Although primarily appealing for patients with tumors that are...
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