... manifestation and natural course of late -onset Pompe disease in 54 Dutch patients Brain 2005;128(Pt 3):671-677 Chapter 79 Disease severity in children and adults with Pompe disease related to age and disease ... renewed the interest in and necessity of a comprehensive documentation of the disease severityand progression The clinical and genetic heterogeneity of the non-classic or late -onset forms of Pompe ... enhance the understanding of the variability, progression and natural history of Pompe disease, and in particular of the non-classic or late -onset form, was recognized by Erasmus MC and the International...
... kerosene and LPG on one hand and other petroleum products that are close substitutes (e.g commercial kerosene and LPG, and diesel) have led to illegal diversion of domestic fuels to the commercial and ... go beyond indoor air pollution and affect the household economy, women’s time and activities, gender roles and relations, safety and hygiene, as well as the local and global environment For example, ... monitoring and evaluation, including exposure assessment, indicators and systems for data collection at national level and for poor rural and urban communities where the need for information and action...
... Impact on the Client and Family 243 Family 10 Linda L.Caregiving 245J Lutz Pierce and Barbara Introduction 245 Problems and Issues Interventions 252 262 Care Recipient, Caregiver, and Caregiving System ... 391 Client 15 Elaine T .and Family Education Miller Introduction 395 395 Influences on Teaching and Learning 403 Educational Interventions for the Client and Family Summary and Conclusions References ... alteration in structure and function Illness, on the other hand, is the human experience of symptoms and suffering, and refers to how the disease is perceived, lived with, and responded to by individuals,...
... just wrong and illogical I have watched the emergence of a new way to think about, assess, identify, and understand learning disabilities Although we still have a lot to learn and understand about ... and Chris Riley-Tillman (Tanya Eckert) I am heartened by the new generation of researchers and leaders who have pushed CBA to levels yet unknown—Amanda VanDerHeyden, Matt Burns, Ted Christ, and ... better and more radiant as the years go on, and my children, Dan and Jay, who continue to amaze me at the turn of every corner I’ve watched Dan move forward in a successful career, as a new husband...
... historical leadership and ability to mobilize science in the service of technological change Today, not only Japan, Korea, and Germany but also China and India are producing engineers and scientists who ... sanctioning union recognition and bargaining for federal employees Yet in banking and financial services, in the crucial industrial South, and among the rapidly expanding scientific and technical categories, ... experiments, and Lyell's development of the science of geology, each of which exhibited characteristics of both the older science and the new technoscience From Lyell's work in the 1820s and 1830s...
... ficolin-3 on the one hand and the severity of ischemic stroke and the infarct size on the other hand, as discussed above It is well known that both the high baseline NIHSS score and the high serum ... GF, ZsI and PG conceived of the study, and participated in its design and coordination, and helped to draft the manuscript; L-MT and M-OS carried out the immunoassays; GSZ, T, GP, KH, RSZ and ZSz ... ficolin-3 and high CRP levels on the one hand and the unfavorable outcome of the disease on the other hand, we repeated the analysis as above in the follow-up samples by including ficolin-3 and CRP...
... pain severityand mean changes in anxiety and depression Relationship between change in pain severityand mood based on the anxiety (A) and depression (B) subscales of the Hospital Anxiety and ... relationship between change in pain severityand mean change in severity of patient-reported sleep disruption Relationship between change in pain severityand change in severity of patient-reported ... Health and Quality of Life Outcomes 2011, 9:17 http://www.hqlo.com/content/9/1/17 quantified and expressed Therefore, characterizing and quantifying the relationship between pain severityand corresponding...
... £324,511 While the usage and cost of conventional and depot medications remained constant, the usage and cost of atypical antipsychotic drugs, particularly olanzapine and risperidone, increased ... consent for AM and CS to administer ratings of symptoms, side effects, general function and quality of life The current medication regime and the patients' general mental health and well-being ... anxiety symptoms, restlessness and a tremor of several months' duration He was advised to reduce and stop his chlorpromazine and procyclidine over a three month period, and reduce the dose of lithium...
... positive charge and an Liu et al Journal of Biomedical Science 2011, 18:29 http://www.jbiomedsci.com/content/18/1/29 amphiphilic structure with the overall balance and distribution of basic and hydrophobic ... flavoprotein (NDUFV2) and its association with early -onset hypertrophic cardiomyopathy and encephalopathy Journal of Biomedical Science 2011 18:29 Submit your next manuscript to BioMed Central and take full ... full-length NDUFV2 (lanes and 5) and the c-myc -tagged NDUFV2 lacking the first 18, 32, and 50 residues respectively (lanes 2-4) Cell lysates were resolved by 15% SDS-PAGE, transferred, and probed with...
... the onset of meiosis and sexual ES formation Results Ovary and ovule morphometrics Regressions between ovary and ovule lengths at meiosis (dyad to early tetrad) and at the 1-nucleate ES (ES1) and ... accelerate onset of reproduction, whether apomictic or sexual The present study adds onset of meiosis and sexual ES formation to onset of the vegetative/floral transition, apomictic ES formation, and ... (young funiculus) grows inward and perpendicular to the inner ovary wall As the ovule grows, the nucellus and integuments form and undergo anisotropic curvature downward and away from the developing...
... medication (24% placebo and 35%, 30% and 33% in the paliperidone palmitate 39, 156, and 234 mg Day arms, respectively) and approximately 60% were using a benzodiazepine (65%, 67%, 58%, and 59%, respectively) ... dose (0.30, 0.43, 0.42, and 0.49 at Days 22, 36, 64, and endpoint, respectively), and the 234 mg dose (0.41, 0.40, 0.48, and 0.55, respectively) The 39 mg arm had lower and relatively constant ... (160) and 155 subjects were randomized to the 234 and 39 mg Day treatment arms, respectively Administration of the Day doses were primarily (99%) in the deltoid muscle (3 paliperidone palmitate and...
... 1·5 T MRI system and a dedicated breast coil The imaging was obtained before and after intravenous administration of gadolinium, using SPGR and STIR sequences, completed by MIP and MPR reconstructions ... ultrasound (US) and magnetic resonance imaging (MRI) findings with clinical and pathologic correlation In the literature, only in one case has previously reported of the ultrasound and magnetic ... high concentrations of oestrogen, progesterone and prolactin promote the growth of ducts and the formation of tubuloalveolar structures; progesterone and prolactin are known for their synergistic...
... after the onset of infection (peritonitis/pneumonia), within 12 hours after the onset of septic shock, and 72–96 hours after the onset of septic shock With each measurement, haemodynamic and oxygen ... Nicotine dependence and alcoholism epidemiology and treatment J Psychoactive Drugs 1992, 24:123-129 41 Spies CD, Sander M, Stangl K, Fernandez-Sola J, Preedy VR, Rubin E, Andreasson S, Hanna ... height, weight and Acute Physiology and Chronic Health Evaluation III score [20] were documented Diagnosis of chronic alcohol abuse and alcohol dependence The history was recorded, and an alcoholism...
... salaries of technical personnel involved in laboratory work and for shipping and handling of data and specimens and presentation of data at scientific meetings Additional support, which provided more ... MCC drafted the protocol, collected and analyzed data, and wrote the report NM did the analyses and helped in analyzing and writing of the report DS, RB, CM, SH and MT had substantial contributions ... conditions and thereby improves the diagnostic and prognostic accuracy Authors' contributions BM had the idea for the study and directed study design, data collection and analysis and writing...
... salaries of technical personnel involved in laboratory work and for shipping and handling of data and specimens and presentation of data at scientific meetings Additional support, which provided more ... MCC drafted the protocol, collected and analyzed data, and wrote the report NM did the analyses and helped in analyzing and writing of the report DS, RB, CM, SH and MT had substantial contributions ... conditions and thereby improves the diagnostic and prognostic accuracy Authors' contributions BM had the idea for the study and directed study design, data collection and analysis and writing...
... in serum and CSF in the bacterial meningitis group are summarized in Table Cortisol and cytokines in cerebrospinal fluid and serum Cortisol and cytokine CSF concentrations in all groups and levels ... (Behring), with normal range between and mg/ml Analysis of cytokines in cerebrospinal fluid and serum Concentrations of IL-1β, IL-6, IL-8, IL-10, IL-12 and TNF-α in CSF and serum (only in patients with ... IL-12 and TNF-α) andseverity of bacterial meningitis Also, analyses revealed that serum cortisol levels correlated positively with IL-6 (r = 0.696, P < 0.001), IL10 (r = 0.501, P = 0.001) and...
... CD25+Foxp3+ cells in their spleen and regional lymph nodes (Nandakumar and Kumaraguru, Unpublished) HSV is known to engage TLR-2, andand upregulate these TLRs on dendritic cells and CD8+ T cells The constant ... produce IL-2, IFNγ and LTα and their development is regulated by the transcription factors T-bet and STAT-4 For their part, the Th2 cells are regulated by STAT-6, c-maf and GATA-3 and they produce ... histamines, prostaglandins, chemokines and cytokines leading to smooth muscle contraction, increased vascular permeability, recruitment of more Th2 cells and eosinophils and release of neuropeptides...
... JO and JAR carried out the determination of MPM-9 and TIMP-1 and made substantial contributions to the analysis and interpretation of data JMBL and YB carried out the determination of TNF-α and ... sepsis patients and 50 controls in terms of age and sex Higher serum levels of MMP10 (P < 0.001) and TIMP-1 (P < 0.001), and nonsignificantly Table Comparison of MMP-9, MMP-10, and TIMP-1 serum ... observed a significant correlation between MMP-10 and TIMP-1 and several markers of sepsis severity, such as SOFA and APACHE-II scores, lactic acid, and markers of coagulopathy; whereas MMP-9 negatively...
... 0.0003 by rank and P < 0.0001 by trend) and base deficit (P = 0.0019 by rank and P < 0.0001 by trend) There is a strong positive correlation between HMGB1 and ISS r = 0.41, P < 0.0001), and a similar ... time, mechanism (blunt or penetrating) and severity, pre-hospital fluid administration, time of arrival in the trauma room and admission vital signs The Injury Severity Score (ISS) was used as a ... r = -.23, P = 0.004), and positively correlated with t-PA (P = 0.0001 by rank and trend, Spearman correlation r = 0.46, P ≤ 0.0001 and D-Dimer levels (P = 0.001 by rank and trend, Spearman correlation...
... Competing interests LTR, RBO, KS, and DBO are employed by DMI Life Sciences, Inc and have stock options through DMI Life Sciences, Inc RBO and DBO own stock and have patent applications pending ... functions as mentioned before, and the importance of ROS in the regula- Page of (page number not for citation purposes) Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2009, ... oxidation-reduction potential; ISS: injury severity score; SAA: serum amyloid A Page of (page number not for citation purposes) Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2009, 17:57...