... manuscript. FE and RB partic-ipated inthe design and coordination ofthe study, includ-ing the animal experiments. RWK contributed to the design of the study, including the animal experiments, and partici-pated ... ele-vated inthe LN than inthe SM [19], in line with the differentmode of induction ofthe disease, which favors spread of the arthritogen to the regional LNs [23]. Both the pathology and the sequence ... example by producing certain sets of cytokines that influence the quality and extent of the inflammatory process [6]. Cytokines, in turn, can elicit the production of tissue-degrading enzymes, a...
... decreases inthe number of infected cells/level of viral replication inthe GALT and plasma viral load during primary infection with SIV, wehypothesized that the GALT was the principal source of the ... compartmentalisation ofthe virus in various cell subtypes inthe peripheral blood duringthe chronic phase of infectionFigure 7Changes in immunological parameters and compartmentalisation ofthe virus in various ... primary and chronic infections. Subsequent viral compartmentalization inthe main targetcells ofthe virus in peripheral blood duringthe chronic phase of infection was evaluated by cellsorting and...
... affect-ing the capability to sense invading microorganisms, butrather the appropriate initiation and modulation of the innate immune response. These findings are supportedby the fact that following ... Center and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Geert Grooteplein 8, Nijmegen 6525 GA, The Netherlands, 34th Department of Internal Medicine University of Athens, ... heterozygous and 5 homozygous. The distribution of SNPs inthe studiedpatients andthe cohort of healthy controls is shown in detail in Table 1.Clinical influence of genotypes on postoperative infection...
... commissioner of prisons, ZPS] and judge fellow inmates and mete outpunishments, including beatings, through night-timecourts in their cells.According to both inmates and prison officials,drinking ... drug-resistant TB includes the use of second-linedrugs, with individual case management including a his-tory of drug use inthe country andthe individual [31],such procedures are unheard ofin Zambian ... and an in- depth inter-view to provide a way of systematically presenting keyindicators, as well as of allowing more thorough docu-mentation of conditions and nuanced understanding of the interrelation...
... questions of any of the villagers. The reason fo r the pictures ofthe frontview is because they do the walls correctly in the front, but on the sides andthe back, as well as the roof, they leave ... survivors. Of these,nine relief worker interviews and four survivor inter-views were conducted in Thailand duringthe latestround of data collection, in May-June 2009. Na mes of participants and ... assess the human rights situation during the later phases ofthe relief effort, o ne year after the storm. The findings presented here include personal accountsfrom interviews conducted during the...
... expression and activation of cytokines and chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury inthe upper gastrointestinal tract leading ... leading to increase inthe permeability ofthe gut mucosa to endotoxins [43, 44]. These factors are involved in ethanol-induced liver damage. Thus, the direct injection of low concentration of ethanol ... with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma derived cell lines . The resistance against anticancer...
... stored-product insect pests. In view ofthe scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain pro-tection has increased and stands as the main alternative to ... evaluate the toxicity of allyl ITC in grain, we could show that 20 μL·L−1air (=20gm−3) and exposure time of 1 day were not effective in killing the insects at the bottom ofthe column when the fumigant ... applied at the upper layer ofthe grain. Addition of CO2 and circulationcaused 100% kill at the different heights. Increasing the exposure time to 4 days and cycling was enough to obtain 100%...