looking at the future of translational stem cell research and stem cell based therapeutic applications priority setting and social justice
Finding Form: Looking at the Field of Organizational Aesthetics docx
... an epistemological argument that aesthetics was the way to get at the feel of an organization Then in 1996, there was a special issue of Organization in which Strati (1996) argued that aesthetics ... suggested that future research in organizational aesthetics should address the aesthetic experience of everyday organizational life, organizational design and issues of form, and intervention and research ... quadrant that we see the real hope for organizational inquiry that aesthetics offers us The use of artistic forms to look at aesthetic issues offers a medium that can capture and communicate the felt...
- 21
- 405
- 0
Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
... prime-boost immunization regimens requires a deeper understanding of the mechanism of action of DNA vaccination A key observation from many studies to date is that interchanging the order of vectors ... we recognize the importance of CD4+ T cells and the possibility that these cells may influence the outcome of vaccine protocols with respect to PD-1 expression by CD8 + T cells PD-1 and co-inhibitory ... autoimmune setting, showing the pivotal negative regulatory role of PD-1 both at the level of T cell expansion as well as during in situ activity [52] Bot et al Journal of Translational Medicine...
- 11
- 505
- 0
Tài liệu The future of cinema is smooth, crisp and amazing docx
... in the past two years in North America and globally In the United States, the National Association of Theater Owners (NATO), in its annual state of the industry report in Spring 2011, said of ... acceptable frame rate they could use for showing these new “talking” movies with relatively smooth motion Some of the biggest movies on the horizon – a pair of Lord of the Rings prequels and Avatar’s sequels ... embrace the tone and warmth of 2" magnetic recording tape and old 33 RPM vinyl records Digital removes the flaws, they concede, but at the expense of character Worse still, with the relatively...
- 8
- 639
- 0
the future of money how mobile payments and the digitization of money will change everything docx
... new generation of real-time, insight driven, shopping and financial tools End of the days of consumers being “dumb” at point of sale Consumer empowerment to the max 19 There are a variety of hurdles ... and Financial Services sectors But what’s the real story here? MOBILE PAYMENTS? A real-time, two-way, powerful and flexible, digitization of money 10 FUTURE OF MONEY 11 First, a thought starter… ... enable the “check-out” process to occur in-aisle, at home, anywhere As a result, mPayment will challenge and redefine– long-standing assumptions of how stores are designed 18 The arrival of mobile...
- 29
- 343
- 0
At the heart of student migration education, mobility, and the time space production of everyday life
... this set of scholarly literature gathers insights from a range of theories on the embodied, the emotional, and the non-representational to draw attention to the sociality and materiality of everyday ... grids of relations, technologies and strategies aimed at the control of time and colonization of the future For instance in Ennew’s (1994: 126) critique of the “timetabling effect” of the “curricularization”, ... the assumptions that people make about their lives in the past, present, and future Whether these assumptions are figments of the mind or products of material relations, a close examination of...
- 130
- 550
- 0
At the heart of student migration education, mobility, and the time space production of everyday life
... through the changing configurations of time and space This underlines the complex and contingent processes that are involved in the production of human subjectivities and relations at the heart of the ... I show that the motivations, mobilities and experiences of education migration, and the diverse transnational connectivities that they are refracted through, are highly differentiated and constantly ... students at the heart of the everyday, quotidian, and transnational geographies of education migration, geographers have expounded on the power of space and place in producing, differentiating, and maintaining...
- 8
- 238
- 0
Derailing the future of economic growth demographic risks and financing pressures facing the UK SME economy
... healthcare and welfare provision, national debt and wider social implications However, it is notable that there has been less attention given to the implications for the small business and the UK ... necessity rather than will 12 Derailing the future of economic growth: The demographic time bomb facing the UK SME economy The challenge of transferring the business to the next generation There is ... move on The ageing of SME owners and the workforce, as with the ageing of the overall workforce, has implications for the growth prospects of SMEs – as well as the wider economy – in terms of productivity,...
- 16
- 226
- 0
The impact of corporate governance on research and development voluntary disclosure UK evidence
... brief report of the research findings This is followed by the theoretical and practical implications of the current study Finally, the chapter outlines the limitations of the study and suggests ... practices in the preparation of the Operating and Financial Review (OFR) The report introduces a set of recommendations and implementation guidance It specifies the key elements -29- of the disclosure ... framework that should be addressed in an OFR such as, information with forward -looking orientation that helps others in the assessment of the current and future performance of the firm The report...
- 327
- 342
- 0
Tài liệu New York Times - Looking Back At The Crash Of 1929Pdf doc
... of an office that "this place is depressing." They went elsewhere The men in the uptown offices gathered around the tickers, sat quietly in their chairs or stood along the walls of the room They ... Thousands of traders were able to weather the first storm and answered their margin calls; thousands fell by the wayside Monday and again yesterday, unable to meet the demands of their brokers that ... announced at midday at the time of the first meeting of the banking group According to the announcement the institutions participating in the group, together with other leading banks of the city,...
- 73
- 400
- 0
Stem CELLS and the FUTURE OF REGENERATIVE MEDICINE pdf
... stem cells The National Research Council and Institute of Medicine formed the Committee on the Biological and Biomedical Applications of Stem Cell Research to address the potential of stem cell research ... assess the scientific and therapeutic value of stem cells The presidents of the National Academies agreed and provided most of the funding that supported the production of this report The Ellison ... Library of Congress Cataloging-in-Publication Data Stem cells and the future of regenerative medicine / Committee on the Biological and Biomedical Applications of Stem Cell Research, Commission...
- 112
- 628
- 0
Think in paper – The future of paper begins at Voith Paper. pot
... changing The SpeedSizer coating unit is equipped with an automatic coat weight CD profiling device The combination of coater, Profilmatic R control software and the associated actuator system of the ... available on the market Technology that convinces – One Platform Concept The new PM is based on the One Platform Concept With the One Platform Concept the economic efficiency of the system and the quality ... entire process from the wet end up to the coating station In accordance with the basic concept of the machine, the system idea is in the forefront also in the case of the chemicals The online calender...
- 76
- 727
- 0
Looking at the label and beyond: the effects of calorie labels, health consciousness, and demographics on caloric intake in restaurants
... All of the authors were involved in designing the research BE and JLL conducted the research and DD oversaw management of the restaurant BE had primary responsibility for analyzing the data and ... Updated Systematic Review of the Literature Int J Behav Nutr Phys Act 2011, 8:135 Backstrand JR, Wootan MG, Young LR, Hurley J: Fat Chance: A Survey of Dietitians’ Knowledge of the Calories and Fat ... income, and education The average levels of health consciousness were also compared across the categories of diners as well as the proportion of people who responded that taste or health was the...
- 9
- 420
- 0
báo cáo khoa học: " The HPB-AML-I cell line possesses the properties of mesenchymal stem cells" ppt
... consisted of cells with a flattened or spindle-like morphology and that the capability of differentiating toward adipocytes of the spindle-like MSCs was superior than that of the flattened cells Since ... used as negative control Inhibition of CD3+ T -cell proliferation in the presence of HPB-AML-I cells HPB-AML-I cells also secreted calcium, which constitutes the extracellular matrix of the bone, ... which made them distinct from the undifferentiated cells Inverted microscopic examination demonstrated the presence of a number of vacuoles in the cytoplasm of differentiated HPB-AML-I cells (Figure...
- 9
- 284
- 0
Asymmetric cell division in the regulation of neural stem cell self renewel in drosophila melanogaster
... daughter cells of same cell fate or developmental potential whereas asymmetric cell division generates two daughter cells of distinct cell fates and/ or sizes The latter is the one of the most ... Spradling, 2007) On the other hand, intrinsic mechanism relies on the asymmetric localization of cell fate determinants and the proper alignment of the mitotic spindle to ensure that cell fate determinants ... mitotic spindle positioning and polarization at the cell cortex 1.4.3 Asymmetric localization and segregation of cell fate determinants The ultimate goal of this asymmetric cell division machinery...
- 150
- 284
- 0
Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 2
... indicative of the propagation of signals downstream of ALK4/5/7 Hence, the elevated phosphoSMAD2(Ser465/467) level indicates that Lefty2 RNAi triggered the activation of signaling mediated by the ... samples and the control Withdrawal of LIF was used in this assay to allow Lefty2 shRNA knockdown to differentiate the ES cells The cells were then dissociated with trypsin and replated at single cell ... that the regulation of Lefty1 by OCT4, KLF4 and NANOG may be part of the ES cell self renewal mechanism The role of Lefty1 in regulation of ES cell self renewal was hence dissected using loss of...
- 117
- 415
- 0
Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 3
... conclusion, the data presented in this thesis lead to the establishment of Lefty2 as an important regulator of embryonic stem cell fate Also, this thesis extends the current understanding of ES cell ... beyond the established roles of LIF/STAT3, BMP and WNT pathways and that of the core transcriptional regulatory circuitry governed by OCT4, SOX2 and NANOG Furthermore, this thesis is the first ... aim of this project hence serves to identify and delineate the roles of additional factors and pathways that are important for the maintenance of ES cell self-renewal To achieve this aim, a candidate...
- 4
- 184
- 0
Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 4
... AGCTTAAAAAGCATCAACGTACCATGTCAtctcttgaaTGACATGGTACGTTGATGCGGG shRNA3 sense GATCCCCGGTGCATGCTGTAGATGTAttcaagagaTACATCTACAGCATGCACCTTTTTA shRNA3 antisense AGCTTAAAAAGGTGCATGCTGTAGATGTAtctcttgaaTACATCTACAGCATGCACCGGG ... AGCTTAAAAAGGATGTGCCTTTCATGCAAtctcttgaaTTGCATGAAAGGCACATCCGGG shRNA3 sense GATCCCCGTAGCCTCATCCCTAAATTttcaagagaAATTTAGGGATGAGGCTACTTTTTA shRNA3 antisense AGCTTAAAAAGTAGCCTCATCCCTAAATTtctcttgaaAATTTAGGGATGAGGCTACGGG ... shRNA4 sense GATCCCCGTGTGACATGTGCGATAAAttcaagagaTTTATCGCACATGTCACACTTTTTA shRNA4 antisense 165 AGCTTAAAAAGTGTGACATGTGCGATAAAtctcttgaaTTTATCGCACATGTCACACGGG 4.3 PCR based cloning of V5-tagged Lefty2...
- 24
- 298
- 0
Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 5
... Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state Stem Cells 23, 166-185 Wieduwilt Matthew J., (2003) SMAD3 in embryonic patterning, ... inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway Dev Biol 275, 403-421 Varga, A C., and Wrana, J L (2005) The disparate role of BMP in stem cell biology ... implantation depends on maternal expression of leukaemia inhibitory factor Nature 359, 76-79 191 Tabibzadeh, S., and Hemmati-Brivanlou, A (2006) Lefty at the crossroads of "stemness" and differentiative...
- 13
- 229
- 0
Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency
... OCT4 and SOX2 are key regulators of ES cell fate These factors are at the top of the hierarchy of the ES cell regulatory network and they keep ES cells undifferentiated by either the activation of ... with the regulation of the growth and self renewal of iPS cells rather than the induction of pluripotency per se, as overexpression of Klf4 and c-Myc resulted in formation of tumour cells that ... strongly in the left lateral plate mesoderm The splanchnic layer that forms the future circulatory system and gut wall originates from the lateral plate mesoderm During later development and adulthood,...
- 41
- 312
- 0
Appendix identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency
... Description of Ct method used for tabulation of qPCR data For all the qPCR data presented in this thesis, the relative transcript levels for the Ct method gene of interest between test sample and control ... target in mouse Es cells LeftyB (human Lefty1) is regulated by Wnt pathway High expression in ES cells and ICM Differential expression pattern between ES cells and differentiated cells Co-expressed ... expression pattern between ES cells and differentiated cells Reduced expression during retinoic acid induced differentiation of F9 cells High expression in ES cells Link to canonical Wnt pathway •...
- 12
- 183
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008